Clinical trials: Lines Skin
Skin, Skin Microbiome
Examine Impact of Topical Application of Active Versus Placebo on the Skin Microbiome in Sensitive Skin.
The purpose of this study is to build insights to understand how the placebo and active impacts the skin microbiome in women with high skin sensitivity (SS10 > 13) and sun exposure.
- Conditions
- Skin, Skin Microbiome, Skin Microbiota, Skin Ageing
- Trial name
- SkinBiome (NCT07454525)
- Testing
- Active Cream
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Skin Aging
Proof of Concept Anti-ageing Clinical Study in Healthy Subjects
The objective of this POC clinical study is to evaluate the moisturising effects on fine lines and wrinkles, texture, barrier function, hydration and elasticity delivered by 4 weeks of twice daily application of the test product…
- Trial name
- NCT03180645
- Testing
- Test product (Moisturising cream), Positive control (Commercial market place moisturising cream), No treatment
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Skin Aging, Fine Lines of the Face and Neck
TEOSYAL RHA® 1 for Neck Lines, Perioral Lines and Smiling Lines
Prospective, low-interventional, multicentric, open-labelled study to assess the performance and safety of skin beautification treatment by TEOSYAL RHA® 1 for fine lines in the neck, perioral region, and smiling lines including…
- Trial name
- NCT05349799
- Testing
- TEOSYAL RHA® 1, TEOSYAL RHA® 1 and TEOSYAL® PureSense Redensity 1 (needle), TEOSYAL RHA® 1 and TEOSYAL® PureSense Redensity 1 (cannula)
- Where
- 4 sites in Spain
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Skin Aging of Face and Hands, Facial Wrinkles - Rough Texture - Hyperpigmentation
DMAE Oleate for Facial Skin Firmness and Fine Lines in Healthy Adults
This single-arm, cosmetic study will evaluate the efficacy of topical DMAE Oleate on facial skin firmness and lines/wrinkles in healthy adults.
- Conditions
- Skin Aging of Face and Hands, Facial Wrinkles - Rough Texture - Hyperpigmentation, Skin Laxity
- Trial name
- NCT07255560
- Testing
- Topical DMAE Oleate
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bionos Biotech S.L.
Female, Facial Skin
A Quantitative, Cross-Sectional and Observational Study to Characterize Age-Related Structural Changes in Facial Skin of Chinese Women Using Line-Field Confocal Optical Coherence Tomography (LC-OCT)
This is a single-center, non-interventional, observational, cross-sectional clinical study designed to quantitatively and qualitatively characterize skin properties in a cohort of 100 Chinese female Subjects aged 20 to 70 years.
- Trial name
- NCT07415798
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Periorbital Hyperpigmentation, Periorbital Edema
A 12 Week Study to Evaluate the Efficacy of an Eye Cream
This single center, open-label clinical study was conducted to assess the efficacy and tolerance of a topical eye cream when used over the course of 12 weeks by healthy women with moderate to severe under-eye dark circles…
- Conditions
- Periorbital Hyperpigmentation, Periorbital Edema, Fine Lines, Wrinkle
- Trial name
- NCT05807620
- Testing
- Gentle Cleansing Lotion, Facial Moisturizer, Sunscreen SPF 30
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Skin Aging, Skin Hydration
A Clinical Trial to Evaluate the Effects of Naila's Collagen Marine Plus Food Supplement on Skin Hydration, Elasticity, Fine Lines and Wrinkles, and Hair and Nail Health
This is a single-group, open-label, virtual (decentralized) clinical trial evaluating the effects of Naila's Collagen Marine Plus Food Supplement on skin hydration, elasticity, firmness, fine lines and wrinkles, and hair and nail…
- Conditions
- Skin Aging, Skin Hydration, Skin Elasticity, Fine Lines and Wrinkles
- Trial name
- NCT07746076
- Testing
- Naila's Collagen Marine Plus Food Supplement
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gulf Bird
Locally Recurrent and Metastatic Breast Cancer
Phase 2 Study of AMG 386 Plus Paclitaxel With or Without Bevacizumab as First Line Therapy in Her2-Negative Breast Cancer Patients
This is a phase 2, randomized, placebo controlled, multi-center study to estimate the treatment effect and evaluate the safety and tolerability of AMG 386 in combination with paclitaxel and paclitaxel/bevacizumab in the treatment…
- Trial name
- NCT00511459
- Testing
- AMG 386, Bevacizumab, Paclitaxel
- Where
- 77 sites in United States, Australia and 11 more
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Amgen
Skin Laxity, Skin Lines
Improved Skin Anti-aging Outcomes Associated With Collagen Fortified Consumption In 30 to 50-Year-old Women
The goal of this clinical trial is to study the efficacy of collagen supplement on the moisture content and elasticity. 70 participants of 30-50 years old women will be enrolled from two study sites and randomly assigned to use…
- Trial name
- NCT05670977
- Testing
- Study product plus collagen supplement, Study product without collagen supplement
- Where
- 2 sites in China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Guangdong HuaPeptides Biotechnology Co., Ltd.
Skin Manifestations
Tolerability and Efficacy of Anti-Aging Treatment Regimen in Subjects With Photodamage
The subjects will use the test skincare products. This is a full face, twice daily application study, with digital photos and expert grader evaluations at Baseline, 4 and 8 week periods.
- Trial name
- NCT02422836
- Testing
- Three Product Anti-Aging Treatment Regimen
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- US CosmeceuTechs, LLC
Skin Laxity, Skin Lines
The Efficacy of Amway Herbal Drink to Improve Skin Anti-aging
This goal of this two arms, randomized, double-blind controlled trial is to study whether Amway herbal drink could improve skin anti-aging in the middle-aged people of 30-60 years old. The main questions it aims to answer are: 1.
- Trial name
- NCT05986799
- Testing
- Amway Herbal Drink
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Amway (China) R&D Center
Prophylaxis Herpes Simplex
Humoral and Cellular Immune Response of Herpes Simplex (gD) Candidate Vaccines From 2 Different Cell Lines
The purpose of the study is to compare, in healthy HSV seronegative and HSV seropositive subjects, the humoral and cellular immune response of herpes simplex candidate vaccines containing gD from two different cell lines and…
- Trial name
- NCT00698490
- Testing
- Adjuvanted herpes simplex (gD) candidate vaccine GSK 208141, Herpes simplex virus containing gD-Alum
- Where
- Belgium
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Skin Aging on Face, Skin Care Dermocosmetics
Efficacy of Topical Niacinamide Riboside on the Signs of Facial Skin Aging
Niacinamide riboside (topical NR, also known as nicotinamide riboside) is an endogenous compound and a precursor (building block) to the essential cellular co-enzyme, nicotinamide adenine dinucleotide (NAD+).
- Conditions
- Skin Aging on Face, Skin Care Dermocosmetics, Skin Care, Fine Lines and Wrinkles
- Trial name
- NR-RADIANCE (NCT07774000)
- Testing
- Topical niacinamide riboside
- Where
- South Africa
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- ChromaDex, Inc.
Facial Wrinkles, Skin Aging
A Study to Evaluate the Safety and Effectiveness of the Cryo-Touch II Device for the Treatment of Forehead and/or Glabellar Lines
A prospective, non-randomized, multicenter study to evaluate the safety and effectiveness of the cryo-touch II device for the treatment of forehead and/or glabellar lines
- Trial name
- NCT01447342
- Testing
- Cryo-Touch II
- Where
- 3 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Skin Aging, Cheek Wrinkles
TCRM for Correction of Cheek Including Fine Lines
The purpose of this clinical study is to evaluate benefits and risks of injecting TCRM in the cheek including fine lines. The goal is to show that treatment with TCRM will result in correcting the cheek area including the fine…
- Trial name
- NCT07145905
- Testing
- TCRM
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Photoaging, Wrinkle
Same-Day Combination of VI Peel and Botox for Correction of Sun Damage, Fine Lines and Wrinkles
This study is being conducted to improve standards of care in the cosmetic treatment of sun damage, fine lines, and wrinkles. VI Peels® and Botox® have been used cosmetically to improve patient concerns as monotherapies.
- Conditions
- Photoaging, Wrinkle, Sun Damaged Skin
- Trial name
- NCT05162300
- Testing
- Same Day Intervention of VI Peel (Procedure) and Botulinum Toxin (Drug)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vitality Institute Medical Products
Skin
A Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Nutritional Supplement Lumenato and Its Impact on Skin Parameters in Healthy Female Subjects
The purpose of this study is to evaluate perceived changes in skin health and appearance after taking the study product daily for 12 weeks. The study product is a soft gel supplement containing tomato oil.
- Trial name
- NCT04356456
- Testing
- Lumenato
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- LycoRed Ltd.
Wrinkle, Photoaging
An Exploratory Investigation of a Novel Skincare Regimen
This trial will assess the effectiveness of the Aria Trio Complete Facial system in being able to reduce blemishes, lines, and wrinkles.
- Conditions
- Wrinkle, Photoaging, Acne, Skin Inflammation
- Trial name
- NCT05517720
- Testing
- Aria Trio complete Facial System
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Trophy Skin
Skin Cancer, Skin Condition
Non-Linear Imaging of Skin In Vivo
The overall objective of this study is to investigate the potential for the VIO System to display microscopic skin structure in people of different age, sex, race, and skin health.
- Conditions
- Skin Cancer, Skin Condition, Skin Diseases, Skin Lesion
- Trial name
- VISION (NCT05410964)
- Testing
- VIO System
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Enspectra Health
Fine Lines, Wrinkles
A Clinical Study Evaluating the Efficacy and Tolerability of a Topical Facial Treatment For Facial Rejuvenation
This single-center clinical trial was conducted to evaluate the efficacy and tolerability of a topical facial treatment when applied by a license esthetician in clinic in a series of 3 sessions with 1 month intervals, in…
- Conditions
- Fine Lines, Wrinkles, Laxity; Skin
- Trial name
- NCT06629792
- Testing
- Gentle Cleanser, Facial Moisturizer, sunscreen SPF 30
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Revision Skincare