Clinical trials: Lipedema
Lipedema
Building Lipedema Research Resources
Lipedema is a disease marked by subcutaneous adipose tissue accumulation in the lower extremities of females that is accompanied by somatic pain and edema.
- Trial name
- BRR (NCT06180850)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Williams Syndrome, Lipedema
Williams Syndrome Strength, Hormones, Activity & Adiposity, DNA Programming, Eating Study
Williams syndrome (WS) is a rare microdeletion genetic disorder that has a broad phenotype including many endocrine and metabolic abnormalities. Dr.
- Trial name
- SHAAPE (NCT03758651)
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Aerobic Exercise, Lipedema
Comparison of Different Exercise Protocols for Diagnosed With Lipedema
This study was designed to compare the effects of high-intensity interval training and moderate-intensity continuous training on functional capacity, muscle strength, and quality of life in patients with lipedema, and to…
- Trial name
- NCT07873541
- Testing
- High-Intensity Interval Aerobic Exercise Group, Moderate Intensity Continuous Group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Hitit University
Lipedema, Women
The Reliability and Validity of the Turkish Version of the LSQ
Abstract Background/ Aim: The aim of this study was to investigate the reliability and validity of the Turkish version of the Lipedema Screening Questionnaire (T-LSQ).
- Trial name
- LSQ (NCT07061808)
- Testing
- Lipedema Screening Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Gazi University
Lipedema, Osteoporosis
The Relationship Between Lipedema and Osteoporosis
The purpose of this study is to evaluate the relationship between lipedema and osteoporosis and to examine factors that may be associated with osteoporosis in individuals with lipedema.
- Trial name
- NCT07779603
- Testing
- DXA
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Assessment, Lipedema
Physical Therapy in Lipedema Surgery
The goal of this observational study or clinical trial is to know evaluate the effects of a modified Complete Decongestive Therapy protocol using the Godoy Method in the postoperative period following lipedema surgery.
- Conditions
- Assessment, Lipedema, Vascular Diseases, Dermatologic Complication
- Trial name
- NCT05966779
- Testing
- modified CDT physical therapy protocol, based on Godoy's Method
- Where
- Spain
- Volunteers
- 293 people
- Sponsor
- University of Alcala
Lipedema
Diathermy Effectiveness in Reducing Subcutaneous Adipose Tissue Affected by Lipedema
Diathermy, a therapy that uses deep heat to reach deep tissue layers, is known to induce the breaking down of fatty cells and fibrotic tissue. In lipedema, patients develop fibrosis of their subcutaneous adipose tissue.
- Trial name
- EDRTASAL (NCT05944796)
- Testing
- Diathermy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Camilo Jose Cela University
Lipedema
HYPOXI for Women With Lipedema
The proposed study is for women with lipedema, a painful fat disorder where fat cannot be lost from the legs and hips with diet and exercise.
- Trial name
- NCT03853083
- Testing
- Hypoxi Equipment, Recumbent Bicycle
- Volunteers
- 20 people
- Sponsor
- University of Arizona
Lipedema
Comparison of Complete Decongestive Therapy With Intermittent Pneumatic Compression for Treatment of Lipedema
Lipedema is a chronic, progressive and hereditary adipose tissue disorder characterized by an abnormal increase of subcutaneous adipose tissue, especially in the lower extremities.
- Trial name
- NCT03924999
- Testing
- Combined decongestive treatment (CDT) & Combined exercise, Intermittent pneumatic compression & Combined exercise, Combined exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Hitit University
Lipedema, Obesity
Comparison of Segmental Body Composition Characteristics in Lipedema and Obesity
The aim of this study is to compare the total and regional body composition characteristics of women with lipedema and women without lipedema who are matched for age and body mass index, as determined by the TANITA MC-580…
- Conditions
- Lipedema, Obesity, Body Mass Index, Bioelectrical Impedance Analysis
- Trial name
- NCT07878299
- Testing
- Bioelectrical Impedance Analysis, Numeric Rating Scale, Lower Extremity Functional Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Central Sensitization, Lipedema
The Impact of Metabolic Status on Pain and Central Sensitization in Women With Lipedema: A Cross-Sectional Observational Study
The aim of this study is to evaluate the effect of metabolic markers (HOMA-IR, triglyceride/HDL ratio, HbA1c, waist and hip circumference measurements, BMI, etc.) on pain and central sensitization in patients diagnosed with…
- Conditions
- Central Sensitization, Lipedema, Pain, HOMA-IR
- Trial name
- NCT07468097
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Marmara University
Lipedema, Hypermobility Syndrome (Disorder)
Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema
Lipedema is a chronic adipose tissue disorder that commonly leads to joint laxity, hypermobility, and functional limitations, yet its impact on foot morphology has not been systematically examined.
- Conditions
- Lipedema, Hypermobility Syndrome (Disorder), Pes Planus, Joint Hypermobility
- Trial name
- NCT07294014
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lipedema
The Relationship Between Central Sensitization, Pain, and Psychosocial Factors in Individuals With Lipedema
This cross-sectional study will include women aged 18-75 with clinically diagnosed lipedema and healthy controls. Sociodemographic and clinical data will be collected, and participants will complete the Central Sensitization…
- Trial name
- NCT07240285
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Lipedema
Extracorporeal Shock Wave Therapy in Patients With Lipedema
Lipedema is a chronic adipose tissue disorder characterized by pain, tenderness, disproportionate fat accumulation, and impaired quality of life.
- Trial name
- LIPO-ESWT (NCT07683559)
- Testing
- Extracorporeal Shock Wave Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atlas University
Lipedema
Effects of Intermittent Pneumatic Compression Therapy on Tissue Volume, Pain, and Quality of Life in Lipedema
Lipedema is an inflammatory and painful disease of subcutaneous adipose tissue (SAT) in women that is associated with vein disease and lymphedema. There is controversy on whether there is edema in lipedema.
- Trial name
- NCT06549738
- Testing
- Intermittent pneumatic compression therapy
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Lympha Press
Dercum's Disease
A Study to Evaluate the Efficacy and Safety of CBL-514 in Participants With Dercum's Disease Lipomas
This Phase 2 study will be an open-label and randomized study to assess the efficacy and safety of CBL-514 in participants with Dercum's Disease lipomas.
- Trial name
- NCT05387733
- Testing
- 10 mg CBL-514 per injection, 15 mg CBL-514 per injection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Caliway Biopharmaceuticals Co., Ltd.
Lipedema
Effect of Ketosis on Pain and Quality of Life in Patients With Lipedema
Lipedema is a female progressive fat disorder, characterized by a symmetrical increase in subcutaneous adipose tissue in the lower extremities with the exception of the waist.
- Trial name
- Lipodiet (NCT04632810)
- Testing
- Ketogenic low energy diet, non-ketogenic low energy diet
- Where
- 2 sites in Norway
- Volunteers
- 70 people
- Sponsor
- Helse Nord-Trøndelag HF
Pain, Lipedema
The Relationship of Shear Wave Elastography Findings With Pain Threshold and Quality of Life in Patients With Lipedema
The aim of this study is to evaluate the relationship between disease severity and subcutaneous tissue shearwave elastography findings with pain threshold and quality of life in patients diagnosed with lipedema.
- Trial name
- NCT06196619
- Testing
- SWE:B-mode ultrasound and subcutaneous elastic modulus with shear wave elastography at three level
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Lipedema
Adipose Cellular Kinetics of Lipedema
Lipedema is characterized by an abnormal deposition of adipose tissue, resulting in fluid accumulation, limb enlargement, and pain. Lipedema is often misdiagnosed as simply obesity.
- Trial name
- LIPEDEMA (NCT05394467)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Pennington Biomedical Research Center
Lipedema
Comparison of Triglyceride-Glucose Index and Atherogenic Indices Between Patients With Lipedema and Obese Controls
Women aged 18-75 years with a clinical diagnosis of lipedema and an obese control group will be included in the study. Sociodemographic and clinical data (age, height, weight, medications, etc.) of the participants will be…
- Trial name
- NCT07240298
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital