Clinical trials: Lipids Metabolism
Testicular Cancer, Survivorship
Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors
Late subclinical cardiovascular disease in testicular cancer survivors exposed to cisplatin-based chemotherapy and bone marrow transplant
- Conditions
- Testicular Cancer, Survivorship, ASCVD, Coronary Artery Disease
- Trial name
- NCT05611307
- Testing
- Lipid profile, Coronary artery assessment, Hormone levels for hypogonadism
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Indiana University
Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors
Screening for Disorders of Lipid Metabolism and Familial Hyperlipidemia in Children and Adolescents With Increased Cardiovascular Risk Due to Chronic Diseases Such as Congenital Heart Disease, Chronic Inflammatory Bowel Disease, Celiac Disease and Rheumatic Disorders
Preventive measures are increasingly coming to the forefront of medicine. Many of these measures can be implemented as early as childhood and adolescence.
- Conditions
- Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors, Congenital Heart Disease, Inflammatory Bowel Disease (IBD)
- Trial name
- FAMELIPIDCHILD (NCT07716488)
- Testing
- blood test, questionaire
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- Alexandra Miriam Kiess
Severe Hypertriglyceridemia
To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia
To determine the effect of Pegozafermin on fasting serum triglyceride levels in subjects with Severe Hypertriglyceridemia (TG ≥500 to ≤2000 mg/dL) after 26 weeks of treatment.
- Trial name
- ENTRUST (NCT05852431)
- Testing
- Pegozafermin
- Where
- 177 sites in United States, Argentina and 18 more
- Volunteers
- 369 people
- Sponsor
- 89bio, Inc.
Prediabetes, Insulin Resistance
Food and Metabolism Study
In this study, Investigators are interested in looking at the influence of eating avocados regularly, which are rich in healthy fats, fibers, and unique carbohydrates, on triglyceride and glucose metabolism in people with…
- Conditions
- Prediabetes, Insulin Resistance, Triglycerides, Lipids Metabolism
- Trial name
- FAM (NCT07624500)
- Testing
- Avocado meal plan, Control meal plan
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Satiety, Appetite
A Study of NatureU Burn on Satiety in Healthy Adults
This single-center, single-blind, non-randomized crossover exploratory study evaluated the short-term effects of NatureU Burn on postprandial satiety in healthy adults.
- Conditions
- Satiety, Appetite, Food Intake, Fat Disorder
- Trial name
- NUBURN (NCT07597382)
- Testing
- Glucose Reference Food, NatureU Burn Plus Glucose
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- OmniSolutions Laboratory Holdings Limited
Lipid Disorders and Lipid Measurement
The Very Large Database of Lipids
Closer examination of granular lipid data in a large population offers numerous opportunities to generate new knowledge, ranging from studies examining concordance between commonly used lipid parameters to phenotypic…
- Trial name
- VLDL (NCT01698489)
- Where
- United States
- Volunteers
- 5,051,467 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cholesterol, Elevated, Hypercholesterolaemia
Impact of Phytosterol-Rich Extract on Lipid Profile
The aim of this randomized, parallel, two-arm, placebo-controlled, triple-blind clinical trial is to evaluate the efficacy of a phytosterol- and phytostanol-rich extract on lipid profile parameters in individuals with…
- Conditions
- Cholesterol, Elevated, Hypercholesterolaemia, Lipid Metabolism Disorders, Dyslipidemias
- Trial name
- NCT06657456
- Testing
- Phytosterol-rich extract
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Desirée Victoria Montesinos
Lipid Metabolism Disorders
Effect of Ilex Paraguariensis Harvest Time and Consumption Method of Processed Yerba Mate on the Lipid Profile
Introduction: This project studies the impact of Ilex paraguariensis harvest time, commonly known as yerba mate, and its consumption mode (mate, tereré, and mate/terere) on the lipid profile of consumers in the Department of…
- Trial name
- NCT06896175
- Testing
- Yerba mate consumption (Ilex paraguayensis) A, Yerba mate comsuption (ilex paraguayencis) B
- Where
- Paraguay
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Caaguazu
Obesity & Overweight, Metabolism Changes
Acute and Chronic Effects of Obesity
The goal of this study is to understand if there are differences in the fat, muscle and metabolism of individuals who developed obesity during childhood versus those who developed obesity in adulthood.
- Conditions
- Obesity & Overweight, Metabolism Changes, Lipid Metabolism
- Trial name
- ACEO (NCT07515547)
- Testing
- Weight loss
- Where
- 2 sites in Canada
- Volunteers
- 150 people
- Sponsor
- Concordia University, Montreal
Obesity, Disorder of Lipid Storage and Metabolism
Identification of Novel Skeletal Muscle-derived Factors That Promote Lipid Oxidation (Columbus)
The purpose of this study is to collect data to help researchers identify factors, such as certain proteins or genetic codes, that are secreted from muscle that are associated with the beneficial effects of exercise.
- Conditions
- Obesity, Disorder of Lipid Storage and Metabolism, Lipid Metabolism Disorders, Metabolic Disorder
- Trial name
- Columbus (NCT01911091)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Obstructive Sleep Apnea, Fat Disorder
Metabolism and Sleep Apnea Treatment
The purpose of this research study is to see if obstructive sleep apnea (OSA) is associated with abnormalities in fat metabolism.
- Trial name
- MaST (NCT05539716)
- Testing
- PAP Therapy, Lifestyle Counseling Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Lipid Metabolism Disorders
The Genetic, Protein, and Lipid Basis of Variation in Cholesterol Efflux
The rationale of this research is that deep phenotyping of individuals at the extremes of cholesterol efflux will identify key determinants of efflux that are potential novel therapeutic targets to prevent or reverse…
- Trial name
- NCT04061018
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Lipid Metabolism Disorder
Multicomponent Intervention Study- Blood Donors With High Cholesterol
The purpose and objective of this study is to improve cholesterol treatment among blood donors with FH (Familial Hypercholesterolemia).
- Trial name
- DONATE-FH (NCT05693701)
- Testing
- Implementation Strategy Bundle, Usual care notification
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Texas Southwestern Medical Center
Lipid Disorder, Hypercholesterolemia
Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial
Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders (EMERALD) is a protocolized intervention based on American College of Cardiology/American Heart Association and US Preventive Services Task Force guidelines…
- Conditions
- Lipid Disorder, Hypercholesterolemia, Cardiovascular Diseases, Atherosclerosis
- Trial name
- EMERALD RCT (NCT06488105)
- Testing
- Statin (rosuvastatin 10 or 40 mg daily, depending on risk), Healthy Lifestyle Counseling, Outpatient Followup
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Wake Forest University Health Sciences
Healthy, Omega 3
Observing Metabolism of EPA With Consideration of Genetics And Sex
The goal of this clinical study is to learn how fast EPA is converted to other molecules, including DHA, with consideration of biological sex and genetics in healthy humans.
- Conditions
- Healthy, Omega 3, Metabolism, Lipids
- Trial name
- OMEGA (NCT06975241)
- Testing
- EPA 2.4g/day
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Homozygous Familial Hypercholesterolemia (HoFH), Major Adverse Cardiovascular Events (MACE)
Evaluation of the Effect of Lomitapide Treatment on Major Adverse Cardiovascular Events (MACE) in Patients With Homozygous Familial Hypercholesterolemia
This observational, multicenter, retrospective and prospective study aims to evaluate the effect of lomitapide treatment on Major Adverse Cardiovascular Events (MACE) in patients with Homozygous Familial Hypercholesterolemia…
- Conditions
- Homozygous Familial Hypercholesterolemia (HoFH), Major Adverse Cardiovascular Events (MACE), Dyslipidemia
- Trial name
- LILITH (NCT06832371)
- Where
- 30 sites in France, Greece and 3 more
- Volunteers
- 73 people
- Sponsor
- Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi)
Morbid Obesity, Type2diabetes
Comorbidities Resolution After MGB Surgery and Change in Body Composition
This observational study aims to learn about the correlation between the improving comorbidities associated with obesity after MGB (Mini-Gastric Bypass) surgery and changes in body composition in morbidly obese patients.
- Conditions
- Morbid Obesity, Type2diabetes, Sleep Apnea, Hypothyroidism
- Trial name
- MOGAMBO (NCT06015620)
- Testing
- Mini gastric bypass surgery
- Where
- India
- Volunteers
- 35 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Dyslipidemias
Statin-Intolerance Registry
The Statin-Intolerance Registry will characterize the patient population suffering from statin-intolerance which is a frequent but incompletely understood patient condition with important clinical implications for atherosclerotic…
- Trial name
- SIR (NCT04975594)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- University of Leipzig
HIV I Infection, Cardiovascular Risk Factor
Doravirine Versus Integrase Inhibitors on Backbone of Emtricitabine and Tenofovir Alafenamide in HIV
This research application will explore the impact of the Non-nucleoside reverse transcriptase inhibitor (NNRTI) doravirine in the setting of established Nucleoside reverse transcriptase inhibitors (NRTIs) backbone [Tenofovir…
- Conditions
- HIV I Infection, Cardiovascular Risk Factor, Lipid Metabolism Disorders
- Trial name
- NCT04820933
- Testing
- Doravirine 100 Mg
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of Texas Southwestern Medical Center
Diabetes Mellitus (Type 2), Inflammation
Probiotic Effects in Type 2 Diabetes
Adult-onset diabetes is a disease characterized by high blood glucose levels and is one of the leading causes of cardiovascular disease, blindness, end-stage renal failure, and hospitalization.
- Conditions
- Diabetes Mellitus (Type 2), Inflammation, Probiotics, Antioxidant Effect
- Trial name
- NCT07330388
- Testing
- Probiotic group
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Ege University