Clinical trials: Lipolysis
Healthy Volunteers
Thyroid and Fat Tissue Metabolism
This study will use a technique called microperfusion to examine how thyroid hormones are involved in fat metabolism. The thyroid gland produces two kinds of hormones: T3 and T4.
- Trial name
- NCT00312715
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Fat Burn
Effect of BTL-899 Device for Non-invasive Lipolysis on Human Upper Arms
This study will evaluate the clinical safety and the performance of the BTL-899 device during the treatment of upper arms.
- Trial name
- NCT04643275
- Testing
- BTL-899
- Where
- Bulgaria
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Sedentary Lifestyle
Changes in Serum Fibroblast Growth Factor 21 (FGF21) Levels Correlated With Exercise
We evaluated the effect of two weeks of intensive supervised physical activity in serum fibroblast growth factor 21 (FGF21) levels.
- Trial name
- NCT01512368
- Testing
- Supervised Exercising
- Where
- Mexico
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Fat Reduction
Non-Invasive Reduction of Abdominal Fat
This study is being performed to reduce unwanted abdominal fat using a new applicator for the Zeltiq System.
- Trial name
- JUNO (NCT01101997)
- Testing
- The Zeltiq System
- Where
- 5 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Insulin Resistance, Obesity & Overweight
Effects of Ketone Bodies on Insulin Sensitivity
KETO-SENSE is a clinical research study investigating how ketone bodies affect energy metabolism and insulin sensitivity in humans.
- Conditions
- Insulin Resistance, Obesity & Overweight, Energy Metabolism, Ketone Body Metabolism
- Trial name
- KETO-SENSE (NCT07359625)
- Testing
- Growth Hormone, Human, Oral ketone supplement (KetoAid®, KE4)
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Excessive Weight Gain
A Study of Niacin Regulation
Adults who gain most of their excess weight in the abdominal area typically do not respond to things that "turn off" fat cells the same way as lean people.
- Trial name
- NCT06175403
- Testing
- Niacin
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity, Diabetes
Endocrine Regulation of Lipolysis in Obesity and Diabetes
Adipose tissue (AT) dysfunction is a commonly observed feature of metabolic dysfunction in obesity and diabetes. An important characteristic when examining AT function is the capacity to break down stored lipids (i.e.
- Trial name
- ERLO (NCT02598544)
- Testing
- adipose tissue sampling
- Where
- 4 sites in Belgium, Netherlands
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Fat Burn
BTL-785F Device for Non-invasive Lipolysis and Circumference Reduction of the Abdomen
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with BTL-785-1 applicator for non-invasive lipolysis (breakdown of fat) of the abdomen and reduction in circumference of the…
- Trial name
- NCT04621019
- Testing
- BTL-785F
- Where
- 2 sites in Bulgaria
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Fat Reduction in the Upper Arm
Non-Invasive Reduction of Fat in the Arms With the CoolFlex Applicator
This study is being performed to reduce unwanted fat in the arm using a new applicator for the Zeltiq System.
- Trial name
- NCT01391923
- Testing
- The Zeltiq System
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Obesity, Abdominal
Microcurrent and Aerobic Exercise Effects in Abdominal Fat
The purpose of this study was to analyze microcurrent short term effects used with aerobic exercise on abdominal fat.
- Trial name
- NCT02110927
- Testing
- Transcutaneous microcurrent, Aerobic exercise
- Where
- Portugal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Type 2 Diabetes
Regulation of Tissue Lipolysis by Insulin in Type 2 Diabetes
Inadequate suppression of intramuscular and adipose tissue lipolysis, and consequent excessive delivery of fatty acids to ectopic tissues (e.g.
- Trial name
- NCT01680133
- Testing
- Hyperinsulinemic euglycemic clamp
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Body Fat Disorder
Pilot Study of CoolTXT for Non-Invasive Fat Reduction
This study is being performed to reduce unwanted fat, in various body areas, using a new applicator and control unit for Zeltiq.
- Trial name
- NCT01517646
- Testing
- The Zeltiq System
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Body Fat Disorder
Non-Invasive Reduction of Fat in the Flanks of Patients With Sharp Body Curvature
The purpose of this study is to evaluate the safety and efficacy of the ZELTIQ System and the CoolCurve+ applicator for non-invasive fat reduction in flanks for a patient population with sharp body curvature.
- Trial name
- NCT01600638
- Testing
- The Zeltiq System
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
LIPOLYSIS
Evaluation of the Safety and Efficacy of REBORN System for Lipolysis Treatment
The Lightfective ReBorn System is intended for non-invasive lipolysis of the flanks in individuals with a Body Mass Index (BMI) of 30 or less. The device is intended to affect the appearance of visible fat bulges in the flanks.
- Trial name
- NCT05507528
- Testing
- reborn treatment
- Where
- 3 sites in United States, Israel
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Lightfective Ltd
Obesity
Fat Perception in Humans (09-0873)
There are many substances naturally present in the mouth that may help us taste fat in food. Two of these substances (lipases and CD36) will be examined in this study.
- Trial name
- OT (NCT01128400)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Fat Disorder
Non-invasive Lipolysis and Improvement of Muscle Tone in Upper Arms
This study will evaluate the clinical efficacy and safety of the BTL-899 device for changes in subcutaneous fat tissue and muscle tissue of arms. The study is a prospective multi-center open-label single-arm study.
- Trial name
- NCT04596241
- Testing
- BTL-899
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Circumference Reduction of Abdomen
Trim II for Noninvasive Lipolysis and Circumference Reduction of Abdomen.
At least 90 female and male subjects, from 6 investigational sites, aged 18-70 seeking non-invasive lipolysis and circumference reduction of abdomen will be enrolled.
- Trial name
- NCT05398159
- Testing
- Trim II
- Where
- 5 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- InMode MD Ltd.
Body Fat
Performance Evaluation of the truSculpt Radiofrequency Device for Lipolysis of Abdominal Fat
Clinical Study to Evaluate the Performance the truSculpt Radiofrequency Device for Lipolysis of Abdominal Fat
- Trial name
- NCT03433417
- Testing
- Cutera truSculpt
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Obesity
The Role of Atrial Natriuretic Peptide in the Lipolytic Process: Effect of Obesity and Exercise
In the developing countries, obesity prevalence is on a dramatic rise. Obesity is related to co-morbidities and as a result, obesity significantly shortens life expectancy and lowers quality of life.
- Trial name
- BALO (NCT02418728)
- Testing
- subcutaneous adipose tissue microdialysis under local beta/alpha blockade
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Body Fat Disorder
Feasibility Study of a Belt Applicator
Evaluate the safety and feasibility of non-invasive fat reduction in the outer thigh with a belt applicator. Applicator design and treatment parameters will be evaluated.
- Trial name
- NCT01767142
- Testing
- The Zeltiq System with Modified Belt Applicator
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics