Clinical trials: Lithotripsy, Laser
Common Bile Duct Stone
Laser vs Electrohydraulic Lithotripsy for Difficult CBD Stones
Common bile duct (CBD) stones are a frequent condition that can lead to severe complications if not treated. The standard approach involves endoscopic retrograde cholangiopancreatography (ERCP) with sphincterotomy and stone…
- Trial name
- NCT07030829
- Testing
- Laser Lithotripsy, Electrohydraulic Lithotripsy
- Where
- 2 sites in Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Upper Ureteric Stones
Efficacy And Safety Of Antegrade Uretroscopic Lithotripsy Versus Retrograde Ureteroscopic Lithotripsy In The Treatment Of Upper Ureteric Stones Measuring > 10 mm In Maximum Dimension. A Randomized Comparative Study
This study aims to assess the efficacy and safety of antegrade flexible ureteroscopic lithotripsy in treating upper ureteric stones >10 mm in maximum dimension and impacted upper ureteric stones irrespective of size in comparison…
- Trial name
- mm millimeter (NCT07362784)
- Testing
- antegrade flexible ureteroscopy for group A, retrograde flexible ureteroscopy For group B
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Urinary Stones
Management of Fragments During Ureteroscopy
The purpose of this study is to study the outcome of patients after ureteroscopy in which all fragments remaining after holmium laser lithotripsy were retrieved compared to those where small, insignificant fragments were left for…
- Trial name
- NCT00637650
- Testing
- Ureteroscopy, Holmium Laser lithotripsy and active retrieval of fragments, Ureteroscopy, Holmium laser lithotripsy, no intent to retrieve any remaining fragment
- Where
- Israel
- Sponsor
- The Chaim Sheba Medical Center
Stone Clearance
Utilizing Holmium Laser for FURS Renal Stone Lithotripsy Comparing Stone Breaking vs. Stone Dusting Settings
Twenty (20) subjects presenting with a renal stone and candidates for FURS (flexible ureteroscopic renal surgery) will undergo a single FURS procedure for a kidney stone as part of the study, using the study device.
- Trial name
- NCT02683993
- Testing
- Lumenis Pulse 120H holmium laser system and 200 DFL ball tip fiber
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Boston Scientific Corporation
Pancreatitis, Chronic, Pancreatic Duct Stone
Comparison of Efficacy of ESWL and Laser Lithotripsy in Chronic Pancreatitis With ERCP
This study will compare the efficacy of ESWL and Laser Lithotripsy in the treatment of pancreatic duct stones with ERCP.
- Trial name
- NCT05326542
- Testing
- ESWL and ERCP, LL and ERCP
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Changhai Hospital
Thulium Fiber Laser, Fans
Fragmentation Vs Dusting With FANS for Renal Stones Less Than 2cm: A Randomized Controlled Study
The use of FANS has changed the operative landscape of RIRS by allowing continuous active suction-assisted clearance of ablated stone material in real time.
- Conditions
- Thulium Fiber Laser, Fans, Lithotripsy, Laser, Renal Stone
- Trial name
- NCT07639385
- Testing
- Dusting, Fragmentation
- Volunteers
- 86 people
- Sponsor
- Bir Hospital
Coronary Artery Disease, Coronary Artery Calcification
Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE)
The FRACTURE Trial is a prospective, non-randomized, single-arm, multicenter, interventional study in US and international centers.
- Trial name
- FRACTURE (NCT06181240)
- Testing
- Intravascular lithotripsy
- Where
- 46 sites in United States, Belgium and 5 more
- Volunteers
- 426 people
- Sponsor
- Bolt Medical
Bile Duct Stenosis
Extracorporeal Shock Wave Lithotripsy Using Latest Lithotripter and Laser Lithotripsy for Difficult Bile Duct Stones
When conventional endoscopic treatment of bile duct stones is impossible or fails, advanced endoscopy assisted lithotripsy can be performed by electrohydraulic lithotripsy (EHL), laser lithotripsy, or extracorporeal shock wave…
- Trial name
- NCT05888077
- Testing
- ESWL_LL
- Volunteers
- 450 people
- Sponsor
- Asian Institute of Gastroenterology, India
Kidney Stones
Laser Versus Ultrasonic Lithotripsy in Percutaneous Nephrolithotomy for Staghorn Stones
This study will be conducted to compare the results of Laser and ultrasonic lithotripsy in disintegration of staghorn stones during percutaneous nephrolithotomy.
- Trial name
- NCT01922414
- Testing
- Laser, Ultrasonic
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Urolithiasis
A Prospective Analysis of Thulium Fiber Laser Efficiency
Patients diagnosed with urolithiasis will be prospectively enrolled in this study. Preoperative diagnostic assessment will be performed using computed tomography (CT).
- Trial name
- NCT07566741
- Testing
- thulium fiber laser lithotripsy
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Bozok University
Nephrolithiasis, Lithotripsy, Laser
Comparison Between Ureterorenoscopy With Lithotripsy Alone Versus Combination With Hydrogel for Kidney Stone Removal
The incidence of kidney stones (urolithiasis) has surged in both developing and developed countries, affecting approximately 15% of the global population.
- Conditions
- Nephrolithiasis, Lithotripsy, Laser, Ureteroscopy
- Trial name
- NCT06469736
- Testing
- Standard of Care Ureterorenoscopy, Standard of Care Ureterorenoscopy with MediNiK
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Technical University of Munich
Nephrolithiasis
A Comparison of Ureteroscopic Treatment of Nephrolithiasis With and Without Moses Technology
Flexible ureteroscopy is characterized as first-line therapy for the treatment of renal stones < 2 cm in size. This involves passing a flexible endoscope into the renal pelvis through the urethra, bladder and ureter in a…
- Trial name
- NCT04505956
- Testing
- Holmium laser lithotripsy with Moses Technology, Holmium laser lithotripsy without Moses Technology
- Where
- 6 sites in United States
- Volunteers
- 171 people
- Sponsor
- Vanderbilt University Medical Center
Benign Prostate Hypertrophy(BPH), Renal Calculi
Stone and Laser Therapies Post-Market Study (SALT)
The objective of the SALT Study is to obtain post-market safety and device performance data for Boston Scientific's Stone and BPH study devices used during a diagnostic and/or therapeutic urinary tract procedure (e.g.…
- Conditions
- Benign Prostate Hypertrophy(BPH), Renal Calculi, Ureteral Stones, Kidney Stones, Calculi, Urinary
- Trial name
- SALT (NCT06982235)
- Testing
- Ureteroscope system, Laser system
- Where
- 5 sites in United States
- Volunteers
- 238 people
- Sponsor
- Boston Scientific Corporation
Kidney Stone, Ureter Stone
Long Pulse Versus Short Pulse Laser Dusting for Renal Stones
The purpose of this research study is to compare how well two treatments work for removing kidney stones. The two study groups include ureteroscopy with long/short pulse lithotripsy to remove kidney stones.
- Conditions
- Kidney Stone, Ureter Stone, Renal Stone
- Trial name
- NCT03608098
- Testing
- Short Pulse Duration, Long Pulse Duration
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Urolithiasis, Proximal Ureteral Stone
Efficacy of Semi-rigid Ureteroscopic Laser Lithotripsy in the Treatment of Proximal Ureteral Stones: a Randomized Controlled Trial
The efficacy of Ho: YAG and TFL combined with semirigid ureteroscopic treatment of proximal ureteral stones will be compared.
- Trial name
- NCT06489366
- Testing
- Thulium Fiber laser (TFL) lithotripsy, Ho: YAG lithotripsy
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Zhongnan Hospital
Kidney Stone, Kidney Calculi
Holmium Vs Trilogy Kidney Stones GUY's 1-2
The desire to reduce complications related to percutaneous access and morbidity related to tract size has led researchers to evaluate PCNL using smaller-caliber instruments. In this context, mini-PCNL has emerged.
- Conditions
- Kidney Stone, Kidney Calculi, Kidney Diseases
- Trial name
- TriHolmium (NCT04559321)
- Testing
- Fragmentation of calculi with 100 W Holmium laser or LithoClast Trilogy EMS and 1.5 mm x 440 mm probe, according to randomization.
- Where
- Mexico
- Volunteers
- 116 people
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Ureteric Stone
to Compare the Effectiveness of Thulium Fiber Laser and Holmium YAG Laser for Ureteroscopic Lithotripsy
This prospective randomized clinical trial aimed to compare the difference in stone ablation rates of TFL and Ho:YAG laser in a clinical setting.
- Trial name
- NCT05218057
- Testing
- Ureteroscopic lithotripsy
- Where
- Hong Kong
- Volunteers
- 46 people
- Sponsor
- Chinese University of Hong Kong
Kidney Stones, Nephrolithiasis
DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones
Kidney stones are a common health problem and may recur frequently, which can affect quality of life and kidney function. Retrograde intrarenal surgery (RIRS) is a minimally invasive treatment used for renal stones, but treatment…
- Conditions
- Kidney Stones, Nephrolithiasis, Renal Calculi
- Trial name
- NCT07516535
- Testing
- Direct In-Scope Suction, Flexible and Navigable Suction Ureteric Access Sheath
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Ain Shams University
Kidney Stones
Use of Antiretropulsion Device in Laser Lithotripsy
The objectives of this post-market evaluation are 1. to assess the capacity of the procedure to be completed with use of only a semi-rigid ureteroscope, without requiring use of a flexible ureteroscope 2.
- Trial name
- NCT00859170
- Testing
- Accordion device
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Percutaneous Systems, Inc.
Kidney Calculi
Flexible Ureteroscopy for Large Renal Stones in Children
This prospective single-arm interventional study evaluated the efficacy and safety of flexible ureteroscopy for the treatment of large renal stones measuring 2 cm or more in pediatric patients.
- Trial name
- NCT07780409
- Testing
- Flexible Ureteroscopic Stone Disintegration
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University