Clinical trials: Lithotripsy, Laser, open to volunteers
Kidney Stones, Nephrolithiasis
DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones
Kidney stones are a common health problem and may recur frequently, which can affect quality of life and kidney function. Retrograde intrarenal surgery (RIRS) is a minimally invasive treatment used for renal stones, but treatment…
- Conditions
- Kidney Stones, Nephrolithiasis, Renal Calculi
- Trial name
- NCT07516535
- Testing
- Direct In-Scope Suction, Flexible and Navigable Suction Ureteric Access Sheath
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Ain Shams University
Pediatric Bladder Stones, Bladder Calculi
Vacuum-Assisted Mini-Percutaneous Versus Transurethral Cystolithotripsy in Pediatric Bladder Stones
This prospective randomized pilot study will compare vacuum-assisted mini-percutaneous cystolithotripsy with standard transurethral cystolithotripsy for the treatment of bladder stones in children.
- Conditions
- Pediatric Bladder Stones, Bladder Calculi, Pediatric Urolithiasis
- Trial name
- VAMPCL-Ped (NCT07614880)
- Testing
- Vacuum-Assisted Mini-Percutaneous Cystolithotripsy, Transurethral Cystolithotripsy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Beni-Suef University
Ureterolithiasis, Renal Calculi
Super-Pulsed Thulium Fiber Laser Versus Holmium:YAG Laser in Retrograde Intrarenal Surgery for Upper Ureteral and Renal Stones
The holmium laser is currently considered the gold standard for lithotripsy on urinary lithiasis, whereas the super-pulsed thulium fibre laser is a relatively new technology.
- Trial name
- NCT07012941
- Testing
- Superpulse Thulium Fiber laser (SPTFL) ureteroscopy for treatment of upper urinary tract stone or renal stone, Holmium: YAG laser ureteroscopy for treatment of upper urinary tract stone or renal stone
- Where
- China
- Volunteers
- 448 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Urinary Stone
Differences in Postoperative Symptoms With Four Ureteral Stents
This is a prospective randomized controlled trial designed to assess the differences in postoperative symptoms related to placement of a 6Fr Percuflex ureteral stents, 6Fr Tria ureteral stents, 4.8Fr Percuflex ureteral stents…
- Trial name
- NCT06083051
- Testing
- 6Fr Percuflex ureteral stents, 6Fr Tria ureteral stents, 4.8Fr Tria ureteral stents
- Where
- United States
- Volunteers
- 272 people
- Sponsor
- University of Wisconsin, Madison
Nephrolithiasis, Urolithiasis
Comparison of Flexible & Navigable Suction Ureteral Access Sheath vs. Antegrade Suction in Retrograde Flexible Ureteroscopy for Lower Calyceal Stones
This randomized controlled trial aims to compare the efficacy and safety of two suction techniques during retrograde flexible ureteroscopy (FURS) for lower calyceal renal stones measuring 1.5-2 cm.
- Conditions
- Nephrolithiasis, Urolithiasis, Endourology
- Trial name
- NCT06889051
- Testing
- Flexible & Navigable Suction Ureteral Access Sheath (FANS), Antegrade Suction via Percutaneous Nephrostomy
- Volunteers
- 120 people
- Sponsor
- Benha University
Biliary Stones
Spyglass DS Peroral Cholangioscope Guided LL or EHL Versus BML for Endoscopic Removal of Complicated Bile Duct Stones
This study aims to compare the overall rate of endoscopic clearance of complicated bile duct stones by Spyglass DS peroral cholangioscopy guided holmium:YAG laser/electrohydraulic lithotripsy versus conventional BML.
- Trial name
- NCT03244163
- Testing
- Spyglass DS cholangioscope, BML
- Where
- Hong Kong
- Volunteers
- 86 people
- Sponsor
- Chinese University of Hong Kong
Renal Calculi
FANS vs Standard Ureteral Access Sheath in fURS
This is a prospective, interventional single blinded, randomized, single-center study designed to compare the efficacy of a ureteral access sheath with integrated suction (FANS) versus a standard ureteral access sheath (UAS) in…
- Trial name
- CLEAR-URS (NCT07463157)
- Testing
- Standard ureteral access sheath, Flexible and Navigable Suction (FANS) Ureteral Access Sheath
- Where
- Italy
- Volunteers
- 134 people
- Sponsor
- IRCCS San Raffaele
Renal Stones, Renal Calculi > 2 cm
Efficacy & Safety of High Power vs. Low Power Holmium Laser in Mini-PCNL for Large Renal Stones
The investigator will compare between holmium laser setting during miniPCNL for renal stones as regard safety \& efficacy
- Trial name
- miniPCNL (NCT07393178)
- Testing
- mini percutaneous nephrolithotomy
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Kidney Stones, Nephrolithiasis
6.3Fr Versus 7.5Fr Mini-Flexible Ureteroscopy for Renal Stones (MINI-FURS)
This prospective, randomized, single-blinded, non-inferiority clinical trial will compare the clinical outcomes and cost-effectiveness of two mini-flexible ureteroscopes (6.3Fr and 7.5Fr) used during flexible ureteroscopy for the…
- Conditions
- Kidney Stones, Nephrolithiasis, Renal Calculi
- Trial name
- MINI-FURS (NCT07798336)
- Testing
- 6.3Fr Mini-Flexible Ureteroscope, 7.5Fr Mini-Flexible Ureteroscope
- Where
- Canada
- Volunteers
- 308 people
- Sponsor
- Sault Area Hospital
Urolithiasis, Nephrolithiasis
Access Sheaths With Aspiration for Renal RetrOgrade Surgery, Randomized CompArative Outcomes
The goal of this clinical trial is to learn whether the ClearPetra ureteral access sheath (Coloplast) is more effective than the Navigator ureteral access sheath (Boston Scientific) in treating intrarenal kidney stones of 1-3 cm…
- Conditions
- Urolithiasis, Nephrolithiasis, Kidney Calculi, Ureteroscopy
- Trial name
- ARROCA01 (NCT07678255)
- Testing
- ClearPetra ureteral access sheath, Navigator ureteral access sheath
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Choledocholithiasis, Pancreatic Duct Stone
Comparing the Efficacy and Safety of Holmium Laser Lithotripsy Versus Electrohydraulic Lithotripsy for the Treatment of Difficult Choledocholithiasis and Pancreatic Duct Stones
The goal of this clinical trial is to learn if a low-power holmium laser works to treat large and/or difficult bile duct or pancreatic duct stones in adults. It will also learn about the safety of the low-wattage holmium laser.
- Trial name
- NCT07418112
- Testing
- Laser lithotripsy with low-wattage holmium laser, Electrohydraulic lithotripsy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rush University Medical Center
Kidney Stones, Nephrolithiasis
Thulium Fiber Laser (TFL) vs Thulio Pulsed Thulium:YAG (p-Tm:YAG)
This research study is being conducted to assess the ability and efficiency of two laser systems to break up kidney stones during ureteroscopy with laser lithotripsy for kidney stone treatment.
- Trial name
- NCT06721975
- Testing
- Thulio pulsed Thulium:YAG (p-Tm:YAG), Thulium Laser Fiber (TFL)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Thulium Fiber Laser, Fans
Fragmentation Vs Dusting With FANS for Renal Stones Less Than 2cm: A Randomized Controlled Study
The use of FANS has changed the operative landscape of RIRS by allowing continuous active suction-assisted clearance of ablated stone material in real time.
- Conditions
- Thulium Fiber Laser, Fans, Lithotripsy, Laser, Renal Stone
- Trial name
- NCT07639385
- Testing
- Dusting, Fragmentation
- Volunteers
- 86 people
- Sponsor
- Bir Hospital
Renal Stones
Ureteroscopic Lithotripsy for Renal Stones Using a Sheathless Approach or Using a Flexible and Navigable Ureteral Access Sheath (FANS)
The primary aim of the study is to compare stone free rates following ureteroscopic (URS) lithotripsy for renal stones with Thulium Fiber Laser (TFL) using a sheathless approach (low power laser settings) or using a flexible and…
- Trial name
- NCT07741084
- Testing
- Sheathless URS, FANS, low power, FANS, high power
- Where
- Norway
- Volunteers
- 225 people
- Sponsor
- Haukeland University Hospital
Kidney Calculi
Comparing Super Pulse Fiber Thulium Laser and Holmium Laser for Ureteral Stone Fragmentation During Ureteroscopy
The goal of this prospective, multicenter, randomized controlled trial is to objectively evaluate the clinical efficacy and safety differences between superpulse thulium fiber laser (sTFL) and holmium:YAG laser (Ho:YAG) in…
- Trial name
- NCT06667557
- Testing
- Superpulse Thulium Fiber Laser (sTFL) Treatment, Holmium:YAG Laser (Ho:YAG) Treatment
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Common Bile Duct Stone
Laser vs Electrohydraulic Lithotripsy for Difficult CBD Stones
Common bile duct (CBD) stones are a frequent condition that can lead to severe complications if not treated. The standard approach involves endoscopic retrograde cholangiopancreatography (ERCP) with sphincterotomy and stone…
- Trial name
- NCT07030829
- Testing
- Laser Lithotripsy, Electrohydraulic Lithotripsy
- Where
- 2 sites in Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Kidney Stones, Urolithiasis
ILY Robotic System vs Manual Flexible Ureteroscopy for Kidney Stone Treatment
The goal of this clinical trial is to compare the efficacy, ergonomics, and safety of robotic versus manual flexible ureteroscopy (fURS) for kidney stone treatment in adult patients undergoing laser lithotripsy.
- Trial name
- iFURS (NCT06996587)
- Testing
- Robotic-Assisted Flexible Ureteroscopy, Manual Flexible Ureteroscopy
- Where
- Lebanon
- Volunteers
- 152 people
- Sponsor
- Albert El Hajj
Nephrolithiasis, Lithotripsy, Laser
Comparison Between Ureterorenoscopy With Lithotripsy Alone Versus Combination With Hydrogel for Kidney Stone Removal
The incidence of kidney stones (urolithiasis) has surged in both developing and developed countries, affecting approximately 15% of the global population.
- Conditions
- Nephrolithiasis, Lithotripsy, Laser, Ureteroscopy
- Trial name
- NCT06469736
- Testing
- Standard of Care Ureterorenoscopy, Standard of Care Ureterorenoscopy with MediNiK
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Technical University of Munich