Clinical trials: Liver Function Tests
Liver Disease
Correlation and Comparison of the HepQuant® Disease Severity Index (DSI) With Hepatic Venous Pressure Gradient (HVPG)
This study plans to learn more about a new test to look at liver function, the HepQuant-Shunt (HQ-Shunt). The HQ-Shunt is being evaluated for safety and effectiveness as an alternative to Hepatic Venous Pressure Gradient testing…
- Trial name
- NCT02523196
- Testing
- HepQuant-SHUNT (Drug and Device) #65,123 (4D-cholate) and IND #65,121 (13C-cholate), Hepatic Venous Pressure Gradient (HVPG)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
NAFLD (Nonalcoholic Fatty Liver Disease), Hep A
Comparative Effects of Mediterranean and DASH Diet on Hepatic Function
Participants were assigned into three groups Control group recieving general dietary guidelines, Mediterranean diet intervention group DASH dietary intervention group
- Trial name
- NCT07622680
- Testing
- Dietary guidelines for fatty liver, Mediterranean diet, DASH diet
- Where
- Pakistan
- Volunteers
- 75 people
- Sponsor
- University of Lahore
Liver Failure
Fast-track LiveR: Study for the Early Identification of Low-risk Patients After Partial Liver Resection by the LiMAx-test
The purpose of this study is to investigate safety and efficacy of intravenously injected 0.4% 13-C-Methacetin solution for the determination of liver function with the LiMAx-test on patients with partial liver resection.
- Trial name
- NCT01785082
- Testing
- 13-C-Methacetin
- Where
- 4 sites in Germany
- Volunteers
- 149 people
- Sponsor
- Humedics GmbH
End Stage Liver Disease
Evaluation of Frailty and Functional Capacity in End-Stage Liver Disease
Development of fibrosis plays a main role in the pathophysiology of liver diseases. The rate of progression in fibrogenesis varies according to the type of underlying liver disease and varies with the environment and host-related…
- Trial name
- NCT04220723
- Testing
- Frailty Assessment, Functional Capacity Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Pulmonary Complications of Liver Cirrhosis and HCC
Pulmonary Function Tests Study in Cirrhotic Patients With and Without Hepatocellular Carcinoma
Cirrhosis is a terminal image of chronic liver disease. During the progression from the compensation period to the decompensation period, various complications occur, and the life prognosis is significantly reduced.
- Trial name
- NCT05963776
- Testing
- spirometry
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Liver Cirrhosis
Study in Patients With Decompensated Liver Cirrhosis
OPAL is a multicenter observational study, following the natural disease trajectory of participants who have permanent damage to their liver caused by scarring, sometimes also referred to as liver cirrhosis.
- Trial name
- OPAL (NCT06380335)
- Where
- 12 sites in Spain, United Kingdom
- Volunteers
- 24 people
- Sponsor
- Resolution Therapeutics Limited
Hepatic Failure, Liver Failure
Cardiox Liver Function Test Pivotal Trial
Performance evaluation of LFT Dye Monitor System using ICG - plasma disappearance rate value (PDR) to assess liver function in normal patients as well as in patients with mild to severe hepatic impairment compared to manual Serum…
- Trial name
- LFT-0002 (NCT02552901)
- Testing
- 0.1 mg/kg ICG Dose, 0.5 mg/kg ICG dose
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cardiox Corporation
Non-alcoholic Steato-hepatitis
: Identification of Non-alcoholic Steato-hepatitis Cases in a Sample of Type 2 Diabetes Patients, with a Disruption of the Liver Function Tests, At the Pointe-à-Pitre University Hospital
Non-alcoholic steatohepatitis (NASH) develops on insulin resistance, especially in patients with carbohydrate tolerance. NASH may progress to more extensive fibrosis, including cirrhosis, but also to HCC with or without cirrhosis…
- Trial name
- STEATOGWAD (NCT06738810)
- Testing
- Fibrotest-actitest/NASHtest
- Where
- Guadeloupe
- Volunteers
- 103 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Liver Diseases, Healthy
Validation of Point of Care Liver Function Tests
This study is testing the accuracy of a point of care device that tests liver function within 20 minutes. The target population will be any adult who had liver function tests ordered and to be drawn on the same day as enrollment.
- Conditions
- Liver Diseases, Healthy, Cirrhosis, Liver, Fibrosis
- Trial name
- NCT03800069
- Testing
- Group K Diagnostic point of care device
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Thyroid Disease
Impact Of Thyroid Dysfunction on Liver Function Tests
This study aims to evaluate the effect of thyroid dysfunction on liver function tests.
- Trial name
- NCT07354048
- Testing
- Control group, Patients with hypothyroidism or hyperthyroidism that are controlled on treatment, Patients with hypothyroidism or hyperthyroidism that are not controlled on treatment
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Diabete Mellitus
The Efficacy and Safety of Empagliflozin - Linagliptin and Empagliflozin- Metformin Therapy in Reduction of Body Weight in Type 2 Diabetic Patients .
The goal of this clinical trial is - Comparison of Empagliflozin - Linagliptin with Empagliflozin - Metformin combination therapy in reduction of body weight in T2DM Patients and it included 200 diabetic subjects with total study…
- Trial name
- NCT07247656
- Testing
- (Empagliflozin 10 mg+ Tab Linagliptin 5mg), Tab Empagliflozin 10 mg + Tab Metformin 500 mg
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Bahria University
Chronic Periodontitis (CP) Subjects.
"Effect of Scaling and Root Planing on Liver Function Test (Alanine Aminotransferase and Aspartate Aminotransferase) in Systemically Healthy - Chronic Periodontitis Subjects: a Clinical Trial."
Aim: To evaluate effect of non- surgical periodontal therapy on liver function in systemically healthy chronic periodontitis (CP) subjects.
- Trial name
- NCT02583841
- Testing
- Scaling and root planing
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Critically Ill
ICG- Liver Test Versus New Biomarkers as Prognostic Markers in Critically Ill Patients
Comparison of ICG liver testing with copeptin and SAPS II score as prognostic markers in critically ill patients.
- Trial name
- Greenpep (NCT01126554)
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- University of Zurich
Diabetes Mellitus, Type 2
Long-Term Effects of Sucontral(TM) on Mild and Moderate Cases of Diabetes Mellitus (Type 2)
In patients with diabetes mellitus type 2 stably adjusted to diet long-term intake of aqueous-ethanolic extract from Hintonia latiflora over more than 12 months leads to a statstically significant amelioration of parameters of…
- Trial name
- NCT00315718
- Testing
- Extract from Hintonia latiflora bark
- Where
- Slovakia
- Volunteers
- 10 people
- Sponsor
- Harras Pharma Curarina GmbH
Sarcopenia, Liver Cirrhosis
ELECTRICAL STIMULATION AND EXERCISE FOR MUSCLE LOSS IN CIRRHOSIS PATIENTS
Introduction: Sarcopenia, whether primary or secondary, substantially impacts the quality of life of patients post-hospital discharge. Compromised functional capacity can lead to a high prevalence of readmissions.
- Trial name
- E-SEEM (NCT07162636)
- Testing
- NMES+, NMES -
- Volunteers
- 112 people
- Sponsor
- Hospital Universitário Professor Edgard Santos
Liver Graft Dysfunction
Delayed CNI-based Immunosuppression With Advagraf After MELD-based Liver Transplantation
Prolonged-release low-dose Advagraf should better protect from CNI-side effects compared to standard immunosuppressive regiments while the rate of rejection is not increased and thus graft function is well maintained.
- Trial name
- IMUTECT (NCT01781195)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Heidelberg University
Perforated Appendicitis
Hyperbilirubinemia in Acute Appendicitis as a Predictor of Perforation
It has recently been published that hyperbilirubinemia is a reliable marker for the preoperative diagnosis of perforated acute appendicitis.
- Trial name
- NCT00528138
- Testing
- Laboratory Test
- Where
- Chile
- Volunteers
- 132 people
- Sponsor
- Cirujanos la Serena
Diabetes Mellitus, Type 1, Liver Diseases
Liver Function Test Abnormalities in Pediatric Type 1 Diabetes
This cross-sectional study aims to determine the frequency, pattern, and predictors of liver function test abnormalities among children and adolescents with type 1 diabetes mellitus attending Assiut University Children Hospital.
- Trial name
- NCT07807553
- Volunteers
- 101 people
- Sponsor
- Assiut University
Non-alcoholic Fatty Liver Disease
Mapping of Metabolic Liver Functions in Patients With Non-alcoholic Fatty Liver Disease
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the western world and an important cause of morbidity and mortality including risk of cardiovascular disease.
- Trial name
- NCT02488941
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Aarhus
Liver Function Tests Abnormalities
Liver Function Test Abnormalities in COVID-19
With the increasing number of COVID-19 infected patients, several studies reported that the liver is the most frequently affected organ after lung damage.
- Trial name
- COVID-19 (NCT04763395)
- Testing
- No intervention
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Sohag University