Clinical trials: Lobectomy Patient
Stage IA Non-small Cell Lung Cancer
Optimal Extent of Pulmonary Resection in Clinical Stage IA Non-Small Cell Lung Cancer
The investigatros hypothesized that selection of surgical procedure according to the pre-defined institutional decision-making algorithm will not compromise the treatment outcomes including overall survival and disease-free…
- Trial name
- OREX-IA (NCT03066297)
- Testing
- Extent of pulmonary resection
- Where
- South Korea
- Volunteers
- 1,018 people
- Sponsor
- Samsung Medical Center
VATS Lobectomy, VATS Segmentectomy
Care Pathway for Patients Undergoing VATS Lobectomy or Segmentectomy
The goal of this study is to create a unified SOP for care of subjects undergoing VATS lobectomy and segmentectomy by members of the Division of Thoracic Surgery.
- Conditions
- VATS Lobectomy, VATS Segmentectomy, Care Pathway, Lung Nodule
- Trial name
- NCT03024294
- Testing
- Post-operative care pathway for patients undergoing VATS lobectomy or segmentectomy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Lung Cancer
LungPoint ATV for Biopsy in Patients Undergoing Lobectomy
The purpose of this study is to evaluate the safety and performance of the LungPoint ATV System.
- Trial name
- LABEL (NCT02130115)
- Testing
- LungPoint ATV System
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Broncus Medical Inc
Postoperative Delirium
Effect of Es-ketamine on Postoperative Delirium Among Old Patients With Lobectomy
The purpose of this study is the efficiency of es-ketamine on postoperative delirium among old patients with elective lobectomy
- Trial name
- NCT04969523
- Testing
- lobectomy
- Volunteers
- 500 people
- Sponsor
- Zhongnan Hospital
Lung Neoplasm Malignant
Immune Response Following Lobectomy Along With or Without Bilateral Transcervical Mediastinal Lymphadenectomy
Any kind of anatomical lung resection for lung cancer with curative intent has to be accompanied by formal mediastinal lymph node dissection.
- Trial name
- NCT04778826
- Testing
- Lymphadenectomy
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Otto Wagner Hospital
Pulmonary Neoplasm
Effect of Pulmonary Rehabilitation on Perioperative Outcomes in Smoker Patients With Lung Cancer
It is reported that smoker patients (>400 cigarette/year) will suffer more postoperative complications than non-smoker patients after lobectomy.
- Trial name
- PREPOSE (NCT03010033)
- Testing
- pulmonary rehabilitation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Ruijin Hospital
Postoperative Pain Management
Dexmedetomidine-Enhanced PCIA After Lobectomy in Nicotine-Dependent Patients
This randomized, double-blind, controlled clinical trial evaluates whether adding dexmedetomidine to an oliceridine-based patient-controlled intravenous analgesia (PCIA) regimen can improve postoperative pain control and…
- Trial name
- DEX-PCIA (NCT07306702)
- Testing
- Oliceridine, Dexmedetomidine
- Where
- China
- Sponsor
- Shenyang Sixth People's Hospital
Non Small Cell Lung Cancer, Lung Cancer Stage 1
Exparel and Marcaine for Pain Management in Thoracoscopic Lobectomy Patients
The purpose of this study is to assess pain management after elective thoracoscopic lobectomy. The study will compare two local anesthetics that are given intra-operatively during lobectomy to see which one helps in better pain…
- Trial name
- BEMP (NCT03682224)
- Testing
- Liposomal Bupivacaine, Bupivacaine-Epinephrine
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Southern Illinois University
Pain
From ACute To Chronic Postoperative Shoulder Pain in Patients for Elective Lobectomy
Shoulder pain is a well known problem after thoracical surgery. The pathogenesis of the pain is uncertain, but mainly a mix of referred pain and mechanical strain to the shoulder. It is believed to last a few days.
- Trial name
- FACTS2 (NCT01552746)
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital
Carcinoma, Non-Small-Cell Lung
Effect of Different Anesthetics on the Change of Alarmins in Lung Cancer Patients Receiving Pulmonary Lobectomy
This study aim to observe and compare the change of alarmins such as high mobility group nucleosome-binding protein-1 (HMGN1), high mobility group proteins b1 (HMGb1), Interleukin (IL)-33 and their soluble receptors including…
- Trial name
- NCT02916147
- Testing
- Sevoflurane, Propofol
- Volunteers
- 40 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Non-Small Cell Lung Cancer
20-Fr Versus 24-Fr Chest Drains After Uniportal VATS Lobectomy for NSCLC
This randomized clinical trial compared two different chest drain sizes, 20 Fr and 24 Fr, in patients undergoing lung lobectomy for lung cancer.
- Trial name
- DRAIN2024 (NCT07827885)
- Testing
- 20-Fr Thoracic Drain, 24-Fr Thoracic Drain
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Opioid Use
Opioid-free Anesthesia With ESPB in VATS Operation
Patients with an ASA score of 3 and below, who will undergo lobectomy with video-assisted thoracic surgery (VATS) method, and who gave informed consent will be included in this study.
- Trial name
- NCT05321576
- Testing
- Erector spinae plane block (ESPB) technique without opioid use
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Marmara University
Video-assisted Thoracoscopic Surgery (VATS), Loxoprofen Sodium Patch
The Efficacy and Safety of Loxoprofen Sodium Patch in Relieving Postoperative Pain After Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is less invasive compared to traditional thoracotomy, but it is still reported that the incidence of acute pain following VATS exceeds 80%.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Loxoprofen Sodium Patch, Local Incision, Postoperative Pain
- Trial name
- NCT07591220
- Testing
- Loxoprofen Sodium Patch on the incision site, Loxoprofen Sodium Patch on the contralateral side
- Volunteers
- 156 people
- Sponsor
- Beijing Tiantan Hospital
Lung Cancer Patients
Inter Costal Catheters for Video-Assisted Thoroscopic (VATS) Lobectomy
A pilot study to observe satisfaction of analgesia with intercostal catheters after VATS lobectomy.
- Trial name
- NCT01213654
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hypertension
Effect of Vasopressin vs Norepinephrine on Pulmonary Oxygenation and Lung Mechanics in Patients With Hypertension Therapy During One-lung Ventilation : Preliminary Study
Hypotension during anesthesia often occurs because reduced systemic vascular resistance and blocked sympathetic nervous system by anesthetic drugs.
- Trial name
- NCT04170751
- Testing
- 16 mcg / cc of norepinephrine(group N), 0.4 unit / cc of vasopressin(group V)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Pneumothorax, Atelectasis
Digital Air Leak Monitoring for Patients Undergoing Lung Resection
Often the decision for chest tube removal or trial of chest tube clamping is based on subjective assessment. This can lead to delay in chest tube removal.
- Trial name
- NCT01810172
- Testing
- Digital pleural drainage system, Dry suction pleura drainage device
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Nova Scotia Health Authority
Postoperative Analgesia
Effect of Paracetamol and Mannitol Injection on Postoperative Analgesia in Patients With Thoracoscopic Lobectomy
This study thoroughly evaluates the efficacy of acetaminophen mannitol injection for postoperative analgesia in patients undergoing thoracoscopic lobectomy, by comparing it with a control group.
- Trial name
- NCT06304181
- Testing
- Paracetamol and Mannitol Injection, Parecoxib
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Opioid Consumption, Postoperative Pain
Effect of ESPB and Rhomboid Block on VATS Method
The aim of this study is to compare ultrasound-guided ESBP and Rhomboid block in terms of postoperative pain management, postoperative opioid consumption and complications in patients undergoing lobectomy with VATS.Patients aged…
- Conditions
- Opioid Consumption, Postoperative Pain, Complication,Postoperative
- Trial name
- NCT05618210
- Testing
- regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Marmara University
Lung Cancer
Effects of Open Thoracic Paravertebral Block on Postoperative Analgesia
The study was aimed to assess the effects of open thoracic paravertebral block on postoperative analgesia in patients undergoing open pulmonary lobectomy under general anesthesia.
- Trial name
- NCT03449563
- Testing
- Open TPVB, Ultrasound-guided TPVB
- Volunteers
- 90 people
- Sponsor
- Kunming Medical University
VATS, Respiratory Muscles
Acute Effects of Visual Feedback-Assisted Inspiratory Muscle Training After Lobectomy
This study aims to evaluate the acute effects of inspiratory muscle training performed with and without a mobile application providing visual feedback on exercise motivation, patient adherence, dyspnea perception, usability, and…
- Conditions
- VATS, Respiratory Muscles, Exercise Training, Lung Cancer (NSCLC)
- Trial name
- NCT07646288
- Testing
- Conventional Inspiratory Muscle Training, Visual Feedback-Assisted Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University