Clinical trials: Local Anesthetic
Local Anaesthetic Drug Adverse Reaction
Computer - Controlled Intraligamentary Local Anaesthesia In Extraction of Primary Molars
Background: Exodontia poses a psychological threat for children, increasing the need for profound local anesthesia to assure painless extraction and maintain child cooperation on the dental chair.
- Trial name
- NCT04739735
- Testing
- Dental Local Anaesthesia
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Endodontic Disease, Endodontic Inflammation
Efficacy of Tetracaine/Oxymetazoline Nasal Spray for Endodontic Treatment
Purpose: To evaluate anesthetic efficacy and overall patient experience with use of Kovanaze tetracaine/oxymetazoline nasal spray for root canal treatment of vital premolar and anterior teeth needing root canal treatment.
- Conditions
- Endodontic Disease, Endodontic Inflammation, Local Anesthesia, Dental Anesthesia
- Trial name
- NCT03502135
- Testing
- Tetracaine HCl and oxymetazoline HCl nasal spray
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Dexmedetomidine, Quadratus Lumborum Block
Impact of Adding Dexmedetomidine as an Adjuvant to The Local Anesthetic in Quadratus Lumborum Block in Patient Undergoing Caesarean Section
The goal of this clinical trial is to evaluate the effects of adding Dexmedetomidine to local anesthetic agent (bupivacaine) for quadratus lumborum block (QLB) after spinal anesthesia in patient undergoing elective caesarean…
- Conditions
- Dexmedetomidine, Quadratus Lumborum Block, Postoperative Analgesia, Caesarean Section
- Trial name
- NCT07072650
- Testing
- Dexmedetomidine
- Where
- Iraq
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Majid Fakhir Mutar Alhamaaidah
Anesthesia, Local, Periodontitis
Efficacy of Intraseptal Anesthesia of 4% Articaine With Epinephrine Achieved by Computer-controlled Delivery System
The aims of our study were to evaluate the clinical anesthetic parameters of the intraseptal anesthesia (ISA), achieved by computer-controlled local anesthetic delivery system CCLADS, for scaling and root planing, as a primary…
- Trial name
- EISAAECCLAD (NCT04392804)
- Testing
- scaling and root planing
- Where
- Serbia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Anesthesia, Local
Efficacy of Transversus Abdominis Plane Block
This study aims to assess the efficacy of Transversus Abdominus Plane (TAP) blocks, a well-established anesthetic technique, to decrease the amount of post-operative pain in patients who undergo minimally invasive gynecologic…
- Trial name
- NCT06274307
- Testing
- Transversus abdominis plane block
- Where
- 2 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Justin Hruska
Symptomatic Irreversible Pulpitis, Post Operative Pain
Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative Pain
The goal of this clinical trial is to compare in Tramadol, Naproxen sodium and Placebo in participants presenting with irreversible pulpitis in their mandibular molar teeth.
- Trial name
- NCT05982392
- Testing
- Tramadol, Naproxen Sodium
- Where
- Pakistan
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Anesthesia, Local
Intraligamental Local Anesthesia Versus Infiltration Technique for Extraction of Grade II Mobility Maxillary Molars
The study aims to assess the use of intraligamental local anesthetic injection compared to buccal infiltration for extraction of maxillary molars suffering grade II mobility in terms of pain control and extraction duration.
- Trial name
- NCT05875350
- Testing
- Intraligamental local anesthetic injection
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Hand Surgery
Ulnar Nerve Block for Procedural Anesthesia - Wrist Versus Palm
Ulnar nerve blockade is necessary for sensory anesthesia and analgesia in the hand during minor procedures. The course of the ulnar nerve in the forearm, wrist, and hand is predictable and has low variability.
- Trial name
- NCT00827658
- Testing
- Volar Wrist Block, Hypothenar Palm block
- Where
- Canada
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Cardiac Arrhythmias
Hemodynamic and Electrocardiographic Effects of Hyaluronidase Associated With Local Anaesthetics
Among the adjuvants to local anaesthetics (LA), the enzyme hyaluronidase is most often used as a diffuser agent of the LA in ophthalmic anaesthesia.
- Trial name
- NCT01719978
- Testing
- 3.6mL 2% Mepivacaine with 1:100,000 epinephrine, Lower Third Molar Extraction, Hyaluronidase
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mauricio Jose Tornelli
Anesthesia Local
Comparison of Combined Sciatic(Winnie's) Femoral Nerve Block, and Subarachnoid Block Anesthesia for Lower Limb Surgery
60 ASA grades- I, II or III patients, undergoing lower limb surgeries, will be randomly allocated in 2 groups of 30 patients each.
- Trial name
- NCT02713685
- Testing
- Subarachnoid block, combined Femoral and Sciatic nerve block
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Government Medical College, Haldwani
Anesthesia, Local
Bupivacaine Supplementation For Postoperative Pain Control In Surgical Removal Of Mandibular Third Molars
Control of postoperative pain is a foremost goal in achieving a satisfactory postoperative recovery. Surgical removal of lower third molars is accompanied by postoperative pain that is at its peak in the first 12 hours.
- Trial name
- NCT02353676
- Testing
- Bupivacaine, SALINE
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cosmozone Dental Clinic
Postoperative Pain
The Effect of Local Anaesthetic Volume on Nerve Block Duration and Nerve Block Duration Variability
The aim is to investigate the effect of perineural administration of a series of different volumes of local anaesthesia (ropivacaine 0.2%) on nerve block duration and the variability of the duration in the common peroneal nerve…
- Trial name
- NCT02829697
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Molar Incisor Hypomineralization, Hypersensitivity
Intraosseous Local Anesthesia System in Children With Molar Incisor Hypomineralization
The goal of this clinical trial is to compare in effectiveness of intraosseous anesthesia and inferior alveolar block anesthesia in children with molar incisor hypomineralization (MIH).
- Conditions
- Molar Incisor Hypomineralization, Hypersensitivity, Composite Restoration
- Trial name
- NCT06461143
- Testing
- %4 articaine with 1:200 000 adrenaline
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University