Clinical trials: Local Anesthetic Effectiveness
Anxiety
Effectiveness of Mobile Applications During the Administration of Local Anesthesia in Pediatric Dentistry
To evaluate the mobile games' effect on patient acceptance of local anesthesia and decreasing dental pain and anxiety levels in pediatric patients.
- Trial name
- NCT04731181
- Testing
- mobile application (little lovely dentist).
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypnosis, Local Anaesthesia
Evaluation of the Effectiveness of Hypnosis Support on Patient Perception of Outpatient Surgery Under Local Anaesthesia
Many clinical trials assessing the effectiveness of hypnosis have been conducted in recent years, some of which show that hypnosis reduces pain perception better than drug treatments administered to control groups, and that it is…
- Conditions
- Hypnosis, Local Anaesthesia, Outpatient Surgery, FACE
- Trial name
- HYPNOFACE (NCT03926403)
- Testing
- State-Trait Anxiety Inventory ("Spielberger Self-Assessment Questionnaire"), hypnosis techniques, local anaesthesia
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Low Back Pain
A Randomized, Equivalence Trial of Percutaneous Lumbar Adhesiolysis and Caudal Epidural Steroid Injections
The purpose of this study is to: evaluate the effectiveness of percutaneous epidural adhesiolysis in managing chronic low back and/or lower extremity pain in patients without post lumbar surgery syndrome or spinal stenosis and…
- Trial name
- NCT01053273
- Testing
- Caudal Epidural Injection, percutaneous adhesiolysis
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah
Knee Osteoarthritis
Perineural Dextrose Versus Local Anesthetic Injections in Knee Osteoarthritis
This prospective observational study aims to compare the clinical effectiveness of perineural 5% dextrose injections and perineural local anesthetic injections in patients with symptomatic knee osteoarthritis.
- Trial name
- NCT07381621
- Testing
- Perineural 5% Dextrose Injection, Perineural Local Anesthetic Injection
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Ankara Training and Research Hospital
Irreversible Pulpitis, Pain
Anesthetic Efficacy of Articaine and Lidocaine in Lower Molars With Irreversible Pulpits
The aim of this study was to verify the effectiveness of an anesthetic called articaine for dental treatment, comparing it with an anesthetic commonly used in dental clinic: lidocaine.
- Trial name
- NCT01912755
- Testing
- 4% articaine with 1:100,000 epinephrine, 2% lidocaine with 1:100,000 epinephrine
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Anesthesia
Efficacy of Injected Local Anesthetic vs Topical Anesthetic in Cosmetic Injectable Fillers.
The purpose of the study is to compare two modalities of local anesthetic administration prior to the placement of cosmetic facial injectable fillers.
- Trial name
- NCT02379221
- Testing
- Injectable, Topical
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Local Infiltration
Hyaluronidase Enzymes and Local Anesthesia
For both groups, local anaesthesia will be administered by one single surgeon and the extraction will be performed by another single surgeon across all subjects.
- Trial name
- NCT06980363
- Testing
- traditional inferior alveolar nerve block by articaine, hyaluronidase plus articain buccal infilteration
- Volunteers
- 20 people
- Sponsor
- Fayoum University
Safety Issues, Post Operative Pain
Safety and Efficacy of Wide Awake Local Anesthesia no Tourniquet Technique (WALANT) in Ankle Removal of Implant Surgery
Safety and efficacy of wide awake local anesthesia no torniquet technique (WALANT) in ankle surgery. Studying risks and benefits from WALANT compared to general anesthesia .
- Conditions
- Safety Issues, Post Operative Pain, Local Anesthetic Complication
- Trial name
- NCT05864664
- Testing
- Wide awake local anaesthesia no tourniquet technique
- Where
- Kuwait
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ali Lari
Dental Anxiety, Pain
Efficacy of Tell-Show-Do Behavior-Management Technique During Local Anesthesia in Preschool Children
This will be a randomized, controlled, parallel-group clinical trial. The aim of this study will be to evaluate the effectiveness of "Tell-Show-Do" Behavior Management Technique versus a Conventional technique (covering the…
- Conditions
- Dental Anxiety, Pain, Infant Behavior, Heart Rate and Rhythm Disorders
- Trial name
- NCT02578160
- Testing
- inferior alveolar and lingual nerve block procedure
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Evelyn Alvarez Vidigal
Obstetric Pain, Obstetric Anesthesia Problems
TAP Block vs LAWI for Analgesia Post-cesarean Section: RCT
Adequate pain control after cesarean delivery is a significant concern both for parturients and obstetric anesthesiologists. Transversus Abdominis Plane (TAP) block and local Wound infiltration with anesthetics are alternatives…
- Trial name
- NCT04637386
- Testing
- Transversus Abdominis Plane Block, Local anesthetic wound infiltration
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Pain, Postoperative, Quality of Life
Efficacy of Two Local Anesthetics on Quality of Life After Endodontic Treatment
In this randomized controlled double-blinded study, subjects will be assigned to one of two study groups to either be anesthetized with Bupivacaine or Lidocaine prior to needed treatment of pulpectomy/endodontic debridement on a…
- Trial name
- B-OHIP14 (NCT04787731)
- Testing
- Bupivacaine Local Anesthetic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Submucosal Resection of the Nasal Septum (SMR)
Four vs. Ten Local Anesthetic Injections for SMR
Submucosal resection of the nasal septum (SMR) could be performed under local anesthetic infiltration performed through ten injections in addition to general anesthesia which was associated with less postoperative pain and…
- Trial name
- NCT02463370
- Testing
- suprazygomatic maxillary area infiltration, non-suprazygomatic maxillary area infiltration
- Where
- Lebanon
- Volunteers
- 120 people
- Sponsor
- Makassed General Hospital
Molar, Third, Surgery, Oral
Comparison of Computer-Assisted and Conventional Local Anesthesia Methods in Mandibular Impacted Third Molar Surgery
The goal of this clinical trial is to evaluate the effects of computer-assisted local anesthesia and conventional local anesthesia on pain perception and dental anxiety during inferior alveolar block anesthesia in impacted…
- Conditions
- Molar, Third, Surgery, Oral, Anxiety, Local Anesthesia
- Trial name
- NCT06852066
- Testing
- Computer-Assisted Local Anesthesia, Conventional Local Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Afyonkarahisar Health Sciences University
Education, Questionnaires
Simulation-Based Team Training for Management of Local Anesthetic Systemic Toxicity (LAST) in Non-Anesthesiologist Surgical Residents
This randomized controlled trial evaluates the effectiveness of a simulation-based multidisciplinary team training program on the management of Local Anesthetic Systemic Toxicity (LAST) among non-anesthesiologist surgical…
- Trial name
- LAST (NCT07463274)
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Gall Stones
Intraperitoneal Techniques of Local Anaesthesia During Laparoscopic Cholecystectomy
Pain following laparoscopic cholecystectomy (LC) results in morbidity and is a barrier to same day discharge. In several trials local anaesthetic (LA) washed over the liver and gall bladder decreases pain.
- Trial name
- NCT01090882
- Testing
- Bupivocaine, 0.9% normal saline solution
- Where
- United Kingdom
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Tenosynovitis
Anesthesia Tumescent for Surgical Management of Tenosynovitis.
The aim of this study is to evaluate the effectiveness of the tumescent anesthesia technique in the surgical management of hand tenosynovitis.
- Trial name
- NCT03914235
- Testing
- Tumescent Anesthesia, Lidocaine, Pneumatic tourniquet
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto Mexicano del Seguro Social
Carpal Tunnel Syndrome, Anesthesia, Local
Ultrasound-guided Peripheral Nerve Block Versus Forearm Bier's Block in Patients Undergoing Carpal Tunnel Release
By means of an observer-blinded, randomized controlled trial, the analgesic efficacy of the forearm intravenous regional anesthesia and the ultrasound guided peripheral nerve block will be investigated in patients undergoing…
- Trial name
- NCT03411551
- Testing
- regional anesthesia
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Local Anesthetic Efficacy
Effectiveness of Nitrous Oxide 50% for Reducing Pain and Distress Associated with Needle-stick in Children
Venipuncture (puncturing of a vein) through the skin in order to insert a vein catheter (also know as cannula) is one of the most common needle-related medical procedures performed in children.
- Trial name
- NCT03342079
- Testing
- Local Anesthetics,(lidocaine 70 mg/tetracaine 70 mg topical patch; Synera)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Dental Phobia, Dental Anxiety
"Study of Pain Perception Using Computer-Controlled Versus Conventional Local Anaesthesia in Children Undergoing Molar Extraction
This clinical trial aims to compare pain perception in children during dental procedures when using a computer-controlled local anesthesia device versus a traditional syringe.
- Conditions
- Dental Phobia, Dental Anxiety, Dental Anesthesia, Dental Anesthesia Efficacy
- Trial name
- CCLAD-Pain (NCT07056101)
- Testing
- A conventional dental syringe, GENI High-Speed Injection, GENI Moderate-Speed Injection
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Tarek MHD kher al saka amini
Anesthesia, Local
Cold Vibratory Stimuli on Pain Perception Governing Infiltration Anesthesia in in Children
Local anesthesia injections are sometimes painful, resulting in antagonistic cooperation, fear, and anxiety in children. This study aims to investigate the effectiveness of vibratory and cold stimulation before the injection to…
- Trial name
- NCT05857033
- Testing
- Buccal and direct palatal injection with the aid of Buzzy, Buccal and indirect palatal injection with the aid of Buzzy, Buccal and direct palatal injection without Buzzy
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Alexandria University