Clinical trials: Locomotion Disorder, Neurologic
Spinal Cord Injury
Treadmill Training With Body Weight Support in Patients With Spinal Cord Injury
Body weight support (BWS) treadmill training uses an overhead harness to give partial support to patients walking on a treadmill.
- Trial name
- NCT00061295
- Testing
- Body weight support treadmill training
- Where
- United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
CP, Gait Disorders, Neurologic
Retention of Whole-body Training Effects on Ambulatory Function in Children With Cerebral Palsy
This study will evaluate the retention effects of a four-week whole-body vibration training intervention in children with Cerebral Palsy.
- Conditions
- CP, Gait Disorders, Neurologic, Locomotion Disorder, Neurologic
- Trial name
- CP_WBVT (NCT04961749)
- Testing
- Whole body vibration training
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Texas, El Paso
Spinal Cord Injuries
Locomotor and Bladder Function in Individuals With Acute Spinal Cord Injury
The loss of movement and walking ability significantly affects quality of life after spinal cord injury. In addition, bladder dysfunction consistently ranks as one of the top disorders affecting quality of life after spinal cord…
- Trial name
- MC-PP-3 (NCT04879862)
- Testing
- Epidural stimulation + Stand Training, Epidural stimulation + Step Training, Epidural stimulation + Bladder Capacity Training
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Claudia Angeli
Spinal Cord Injury
Improving Walking After Spinal Cord Injury
Locomotor recovery is one of the most important goals of individuals with spinal cord injury (SCI). Ambulatory deficits severely impact daily functions resulting in lower quality of life for people living with paralysis due to…
- Trial name
- NCT07223710
- Testing
- Paired Associative Stimulation, Locomotor Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Shirley Ryan AbilityLab
Spatial Perception, Stroke
Effect of Lower Limb Exproprioception Training in Virtual Environment on Locomotion Performance in Stroke Patients
The purpose of this study is to determine if a virtual reality training of foot placement with or without visual cues about the location of the foot in the environment would improve locomotion-related function in persons in the…
- Conditions
- Spatial Perception, Stroke, Virtual Reality, Exercise Training
- Trial name
- NCT04436237
- Testing
- Virtual reality foot placement training
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng Kung University
Parkinson Disease
Effect of L-Dihydoxyphenylserine on Locomotion, Postural Stability, and Fall Risk Reduction in Parkinson Disease
This research study is being done to determine whether treatment with L- Dihydroxyphenylserine (L-DOPS) versus placebo (an inactive substance that looks like study drug) in addition to other Parkinson Disease (PD) drugs will…
- Trial name
- NCT02812147
- Testing
- L-DOPS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Stroke
Virtual Reality and Field Training to Enhance Community Walking After Stroke
While stroke survivors discharged from rehabilitation present with some recovery in mobility, their ability to ambulate in the community remains limited.
- Trial name
- NCT04559373
- Testing
- Virtual Reality and Field Training (VRFT)
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- McGill University
Multiple Sclerosis
The Neural Mechanisms of Split-belt Treadmill Adaptation in People With Multiple Sclerosis
Majority of people with multiple sclerosis experience difficulty with balance and mobility, leading to an increased risk of falls.
- Trial name
- NCT05878873
- Testing
- Split-belt Treadmill, Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Multiple Sclerosis
Biomechanical Characterization of the Locomotion in Multiple Sclerosis Patients
Multiple sclerosis (MS) is an inflammatory chronic disease of the central nervous system. Patients are suffering from balance and gait impairments at the early stage of the disease.
- Trial name
- WALKING-SEP (NCT03756142)
- Testing
- Motion Analysis
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Sensorimotor Gait Disorder, Neurologic Ambulation Disorder
Clinical Study of the L300 Versus Ankle-foot Orthosis (AFO) on Post-Stroke Subjects With Foot Drop
The objective of this study is to determine the effectiveness of the NESS L300 (L300) in improving gait parameters, function, and quality of life among stroke subjects (greater than or equal to 3 months post stroke)with drop foot.
- Conditions
- Sensorimotor Gait Disorder, Neurologic Ambulation Disorder, Gait, Drop Foot, Poststroke Hemiparesis
- Trial name
- L300 (NCT01138995)
- Testing
- Ness L300, Ankle-foot orthosis
- Where
- 11 sites in United States
- Volunteers
- 197 people
- Sponsor
- Bioness Inc
Stroke
HIT-Stroke Trial 2
People who had a stroke at least 6 months prior and who still have difficulty with walking will each be randomly assigned to receive either moderate or vigorous intensity walking exercise.
- Trial name
- HST2 (NCT06268041)
- Testing
- Moderate-Intensity Aerobic Training, High-Intensity Interval Training
- Where
- 3 sites in United States
- Volunteers
- 156 people
- Sponsor
- University of Cincinnati
Gait Training, Locomotion
Gait Training and Brain Changes in Stroke Patients
This study, conducted in collaboration with the National Rehabilitation Hospital (NRH) in Washington, D.C., will look at changes in brain activation and brain responses that occur with gait (walking) training.
- Trial name
- NCT00334230
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Movement Disorders, Parkinson Disease
STEPWISE Parkinson: A Smartphone Based Exercise Solution for Patients With Parkinson's Disease
The aim of this study is to investigate whether a smartphone app can increase physical activity in patients with Parkinson's Disease in daily life for a long period of time (12 months).
- Trial name
- STEPWISE (NCT04848077)
- Testing
- Step count increase with the use of a motivational smartphone application
- Where
- Netherlands
- Volunteers
- 452 people
- Sponsor
- Radboud University Medical Center
Incomplete Spinal Cord Injury
Amplify Gait to Improve Locomotor Engagement in Spinal Cord Injury
Spinal cord injury (SCI) affects ~42,000 Veterans. The VA provides the single largest network of SCI care in the nation. The lifetime financial burden of SCI can exceed $3 million. A major cost of SCI is impaired mobility.
- Trial name
- AGILE SCI (NCT04340063)
- Testing
- Gait training performed on a treadmill, Gait training performed in a Movement Amplification Environment
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- VA Office of Research and Development
Stroke, Hemiparetic Patients After Subacute Stroke
Effects of Locomotion Training With Assistance of a Robot-Driven Gait Orthosis in Hemiparetic Patients After Subacute Stroke
The investigators aimed in this study to investigate the effects of 4 weeks robot-assisted locomotor training on motor recovery of lower extremities and walking ability compared with the conventional gait training in subacute…
- Trial name
- NCT01726998
- Testing
- Robot-assisted gait therapy, conventional gait training
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Yonsei University
Rehabilitation, Parkinson Disease
Golden Walk as Measure of Gait Rehabilitation in Parkinson's Disease
Gait is specifically impaired in Parkinson's disease (PD). External auditory cue based on a binary rhythm tested in PD patients disappear when the stimulus is removed.
- Conditions
- Rehabilitation, Parkinson Disease, Locomotion Disorder, Neurologic, Rhythm; Abnormal
- Trial name
- NCT04706572
- Testing
- Stimulation with external auditory bio-feedback
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Stroke
Robotic Exosuit Augmented Locomotion (REAL) in the Clinic and Community
Previous studies of the exosuit technology have culminated in strong evidence for the gait-restorative effects of soft robotic exosuits for patients post-stroke by means of substitution for lost function.
- Trial name
- REAL-m (NCT05315310)
- Testing
- Soft Exosuit
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Boston University Charles River Campus
Spinal Cord Injury (SCI)
Restoring Walking in Non-ambulatory Children With Severe Chronic Spinal Cord Injury (SCI) (Kids STEP Study)
The Kids STEP Study aims to 1. Determine if walking can be restored in children with incomplete SCI and little to no leg movement 2. Identify the neural pathways that permit recovery of walking
- Trial name
- NCT00488280
- Testing
- Locomotor Training
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Florida
Spinal Cord Injury
Comparison of Post-pinal Cord Injury (SCI) Locomotor Training Techniques
Background: Body weight supported (BWS) locomotor training improves overground walking ability in individuals with motor-incomplete spinal cord injury (SCI).
- Trial name
- NCT01095380
- Testing
- Locomotor training
- Volunteers
- 74 people
- Sponsor
- University of Miami