Clinical trials: Locoregional Anaesthesia
Postoperative Analgesia, Anesthesia; Functional
Comparison of Two Regional Technics In Knee Artroplasty
Purpose: This prospective, randomised, controlled, single-blind, multicentre study was designed to investigate the effects of peripheral nerve block methods (applied using unilateral spinal anaesthesia [USA] on elderly patients…
- Trial name
- CTRTIKA (NCT03021421)
- Testing
- intratechal (subarachnoidal )injection, lombar plexus and sciatic nerve injection
- Volunteers
- 60 people
- Sponsor
- Ordu University
Pain, Postoperative, Developmental Dysplasia of the Hip
Intravenous Dexamethasone to Prolong Caudal Block Analgesia in Children Undergoing Hip Surgery
The goal of this clinical trial is to learn whether a single intravenous dose of dexamethasone prolongs postoperative analgesia after a caudal block in children aged 6 months to 9 years undergoing surgery for developmental…
- Trial name
- DEXA-CAUDAL (NCT07896304)
- Testing
- Dexamethasone, Normal Saline, Caudal Block Anesthesia
- Where
- Tunisia
- Volunteers
- 54 people
- Sponsor
- National Institute of Neurology, Tunisia
Spondylolisthesis, Lumbar Disc Herniation
Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery
Rationale: Lumbar spine surgery is associated with high postoperative pain scores and analgesic use, despite use of multimodal analgesia.
- Conditions
- Spondylolisthesis, Lumbar Disc Herniation, Lumbar Spinal Stenosis, Lumbar Disc Disease
- Trial name
- RCT-ESPB (NCT05345249)
- Testing
- Ropivacaine Hydrochloride Injection, Sodium chloride
- Where
- Netherlands
- Volunteers
- 76 people
- Sponsor
- Ilse van de Wijgert
Cancer
Regional Anesthesia and Endometrial Cancer Recurrence
The purpose of this study is to determine whether recurrence of local and metastatic cancer after open hysterectomy for stage 1 or 2 endometrial cancer is reduced when patients receive epidural anesthesia/analgesia combined with…
- Trial name
- ECA/R (NCT00531349)
- Testing
- propofol general anesthesia, Sevoflurane
- Where
- United States
- Sponsor
- The Cleveland Clinic
Arteriovenous Fistula
Regional Anesthesia for Arteriovenous Fistula
Once kidney function goes below 10 to 15 percent of normal, dialysis treatments or a kidney transplant are necessary to sustain life.
- Trial name
- NCT02305992
- Testing
- Axillary Block with 0.5% Ropivicaine, Stellate ganglion block with 0.2% Ropivicaine, Local anesthetic infiltration with 0.25% Bupivicaine
- Where
- Canada
- Sponsor
- McMaster University
Regional Anesthesia Block, Brachial Plexus Blocks
Comparison Between Ultrasound-Guided Costoclavicular and Lateral-Sagittal Infraclavicular Brachial Plexus Blocks in Adult Distal Upper Limb Surgeries
The aim of the study is to compare the onset time of the costoclavicular approach of brachial plexus block with that of the lateral-sagittal infraclavicular approach in adults distal upper limb surgeries.
- Trial name
- NCT07517809
- Testing
- Costoclavicular brachial plexus block, Lateral-sagittal infraclavicular brachial plexus block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Femoral Neck Fracture
Fascia Iliaca Block in the Emergency Department for Analgesia After Femoral Neck Fracture
Femoral neck fracture is very common in the elderly and can produce severe to moderate pain. As this pathology is not life-threatening, waiting time in the emergency department may be prolonged due to the high number of…
- Trial name
- NCT02433548
- Testing
- Fascia iliaca block
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Cannula Site Pain, Local Anesthesia
Pain Relief During Intravenous Cannulation in Pediatric Patients
Performing intravenous (IV) cannulation to pediatric patients might be much harder than adult ones according to their anxiety levels.
- Trial name
- NCT04246255
- Testing
- Xylocaine 10% Oral
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Yeditepe University
Carotid Endarterectomy
Predictors of Post-clamping Neurologic Deficits During Carotid Endarterectomy With Regional Anesthesia
Patients undergoing carotid endarterectomy may suffer from neurologic deficits (ND) during the carotid cross-clamping due to cerebral hypoperfusion. An associated risk of postoperative stroke incidence is also well established.
- Trial name
- NCT04347785
- Testing
- carotid endarterectomy
- Where
- Portugal
- Volunteers
- 206 people
- Sponsor
- Universidade do Porto
Anesthetics, Local
Split Face Study of the Duration of Local Anesthetics
This is a research study to compare how long injectable pain medications (anesthetics) commonly used in dermatologic surgery are effective for.
- Trial name
- NCT05767749
- Testing
- lidocaine + epinephrine 1:100,000, Ropivacaine 0.5% Injectable Solution, Bupivacaine 0.5% Injectable Solution
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Regional Anaesthesia
Comparison Between Ultrasound Guided Femoral 3 in 1 Block Versus Blind Fascia Iliaca Block Before Spinal Anaesthesia
This study aimed to evaluate the efficacy of ultrasound guided femoral 3 in 1 block versus the blind technique single shot fascia iliaca compartment block as an analgesia method in patients prior positioning for spinal…
- Trial name
- IKH (NCT03139617)
- Testing
- Fascia Iliaca Compartment Block (FICB), 3 in 1 femoral block (FNB)
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- Universiti Sains Malaysia
Local Anesthetic
Efficacy and Safety of Chloroprocaine 3% Gel and Oxybuprocaine 0.4% Eye Drops Anesthesia in Pediatric Population
The goal of this clinical trial is to assess the efficacy and safety of Chloroprocaine 3% eye gel compared to Oxybuprocaine 0,4% eye drops when used for inducing ocular surface anesthesia in pediatric patients.
- Trial name
- NCT05926258
- Testing
- Chloroprocaine 3% eye gel, Oxybuprocaine Hydrochloride 4 Mg/mL Eye Drops
- Where
- 3 sites in Italy
- Volunteers
- 74 people
- Sponsor
- Sintetica SA
Gestational Weight Gain, Regional Anesthesia
Effect of Gestational Weight Gain on Spinal Anesthesia in Elective Cesarean Delivery
This prospective, observational, non-interventional study aims to evaluate the effect of gestational weight gain on regional anesthesia characteristics in pregnant women undergoing elective cesarean delivery.
- Conditions
- Gestational Weight Gain, Regional Anesthesia, Cesarean Delivery
- Trial name
- GWG-CESA (NCT07326644)
- Testing
- Gestational Weight Gain
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Postoperative Pain, Laparoscopic Cholecystectomy Surgery
Impact of Video-Based Patient Education on Physician Trust, Pain, and Anxiety in Laparoscopic Cholecystectomy
This prospective, randomized, single-center, single-blind study aims to evaluate the effects of video-based preoperative education on physician trust, postoperative pain, anxiety, and opioid consumption in patients undergoing…
- Conditions
- Postoperative Pain, Laparoscopic Cholecystectomy Surgery, Preoperative Anxiety, Trust in Healthcare System
- Trial name
- VITAP (NCT07767344)
- Testing
- Video-Based Preoperative Block Education, Standard Verbal Preoperative Block Education
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Sanliurfa Education and Research Hospital
Prostatectomy
Rectus Sheath Block May Relieve Urethral Catheter Pain
This study aimed to investigate the analgesic efficacy of rectus sheath block and its effect on urethral catheter discomfort in robotic prostatectomy operations.
- Trial name
- NCT05242198
- Testing
- Robotic prostatectomy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- V.K.V. American Hospital, Istanbul
Carpal Tunnel Release
WALANT Technique (Wide Awake Local Anesthesia No Tourniquet) for Carpal Tunnel Release.
The carpal tunnel release (CTR) is now performed almost exclusively under regional anesthesia (RA) in France. RA requires the use of a pneumatic tourniquet to limit blood flow to the operated extremity and create a bloodless…
- Trial name
- WALA (NCT04494100)
- Testing
- TRONC, WALANT, Tourniquet
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- CMC Ambroise Paré
Hemorrhoids
Local Versus General Anaesthesia in Stapled Hemorrhoidectomy
The purpose of this study is to determine whether local or general anaesthesia in stapled hemorrhoidectomy leads to a shorter operation time with a better patient comfort.
- Trial name
- NCT00512044
- Testing
- Local anesthesia (pudendal block), general anesthesia (spinal and general)
- Where
- Switzerland
- Sponsor
- University of Lausanne Hospitals
Regional Anesthesia Morbidity
Cervical Plexus Block Combined With Translaryngeal Block for Tracheostomy
Current healthcare delivery models emphasize enhanced postoperative recovery (ERAS) with minimal morbidity and shorter hospital stays. Most tracheostomy cases are tumour patients.
- Trial name
- NCT04697836
- Testing
- ST
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Namik Kemal University
Postoperative Pain
Effectiveness of TAP Block Versus Intravenous Analgesia in Postoperative Pain Management Following Gynecologic Laparoscopic Surgery
Optimal postoperative pain control is crucial in laparoscopic gynecologic surgery, particularly within Enhanced Recovery After Surgery (ERAS) protocols.
- Trial name
- NCT07051499
- Testing
- TAP Block Group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Foggia
Regional Anesthesia
Ultrasound-guided Peripheral Nerve Blocks - a Database
Peripheral nerve blocks are often used in anaesthesia. They can be used as the only method of anaesthesia during surgery or in combination with other methods, e.g., general anaesthesia and sedation.
- Trial name
- Blockbase (NCT06460792)
- Testing
- Ultrasound-guided peripheral nerve block
- Where
- Denmark
- Volunteers
- 5,000 people
- Sponsor
- Nordsjaellands Hospital
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