Clinical trials: Locoregional Anaesthesia
Cataract Extraction, Anesthesia, Local
Cerebral Oxymeter and End Tidal Carbondioxide Values Under Surgical Drapes With and Without Past COVID-19 Infection
Today, phacoemulsification has become the most commonly applied method in the treatment of cataract, which is considered as a public health problem.
- Conditions
- Cataract Extraction, Anesthesia, Local, Optic Nerve Sheath
- Trial name
- NCT05571683
- Testing
- oxygen support
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Duzce University
Regional Anesthesia Morbidity, Hip Surgeries
Pericapsular Nerve Group Block vs. Fascia Iliaca Compartment Block vs. Caudal Block for Hip Surgeries
The study aims to compare the effect of pericapsular nerve group block versus fascia iliaca compartment block versus caudal block regarding Postoperative analgesia in children undergoing hip surgeries.
- Conditions
- Regional Anesthesia Morbidity, Hip Surgeries, Perioperative Analgesia
- Trial name
- NCT07137962
- Testing
- PENG Block, FICB Block, Caudal Block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Trismus
Evolution of Mouth Opening After Mandibular Block
Trismus is an involuntary contracture of the masticatory muscles, blocking the opening of the jaw, first intermittent then permanent and irreducible.
- Trial name
- OBloc (NCT04961554)
- Testing
- loco-regional anesthesia
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anesthesia, Local
Effectiveness of Buccal Infiltration During Vital Pulpotomy After Administering Two Analgesic Premedications
This Randomized study was designed to assess and compare the effect of two analgesic premedications (Ibuprofen BP 100 mg/5 ml and Paracetamol 200 mg/5ml.) on the anesthetic efficacy of buccal infiltration in vital pulpotomy of…
- Trial name
- NCT03423329
- Testing
- Brufen, Cital
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Post Operative Pain, Stress Response
Effects of Erector Spinae Plane and Caudal Block on Postoperative Stress Response
Inguinal hernia surgery is the most common practice of pediatric surgeons in their clinical practice. As these operations are usually day case procedures, maintaining adequate analgesia is an important component of perioperative…
- Conditions
- Post Operative Pain, Stress Response, Erector Spinae Plane Block, Caudal Block
- Trial name
- NCT05633173
- Testing
- Ultrasound-guided erector spinae plan block, Ultrasound-guided caudal block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Anxiety, Surgery
Could Music be an Alternative to Sedation in Patients Treated Total Knee Arthroplasty With Regional Anesthesia?
Background: Anxiety is a common phenomenon in hospitalized patients. In order to reduce it during the surgical procedure, sedatives and anxiolytics are used, which can cause undesirable side effects for patients.
- Conditions
- Anxiety, Surgery, Drug Toxicity, Anesthesia
- Trial name
- NCT03882541
- Testing
- Music therapy, Sedation with midazolam
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de l'Anoia
Knee Arthroscopy
Intra-articular Versus Intravenous Dexmedetomidine in Arthroscopic Knee Surgeries Under Local Anesthesia
The present study will be carried to evaluate the efficacy of intra-articular 0.5 bupivacaine with intra-articular or intravenous alpha-2agonist; Dexmedetomidine; for intraoperative anesthesia and postoperative analgesia after…
- Trial name
- NCT02730845
- Testing
- Intra-articular dexmedetomidine, Intravenous dexmedetomidine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Acute Pain, Anesthesia
Effectiveness of Retrolaminar Block in Lumbar Spine Fusion With Multimodal Analgesia
This randomized, blinded, controlled clinical trial aims to evaluate the effectiveness of ultrasound-guided retrolaminar block in reducing postoperative opioid consumption in patients undergoing lumbar spine fusion surgery under…
- Conditions
- Acute Pain, Anesthesia, Lumbar Spine Disease
- Trial name
- RBLUF (NCT07291388)
- Testing
- retrolaminar block
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Postoperative Pain Control
Ultrasound-guided TAP Block Vs Local Wound Infiltration for Analgesia After Cesarean Section.
Adequate pain control after cesarean delivery is a major concern for both parturients and obstetrician, and it usually comprise a combination of systemic and regional techniques.
- Trial name
- NCT04711096
- Testing
- Ultrasound-guided transversus abdominis plane (TAP) block 0.25% bupivacaine.
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Nephrolithotomy, Percutaneous, Anesthetics, Local
Efficiency of Erector Spinae Plane Block For Patients Undergoing Percutaneous Nephrolithotomy
Investigators' goal is to determine whether Erector Spinae Plane Block would provide a better analgesia, help mobilization and early discharge or increase satisfaction for patients undergoing Percutaneous Nephrolithotomy(PNL).
- Conditions
- Nephrolithotomy, Percutaneous, Anesthetics, Local, Nerve Block, Erector Spinae Plane Block
- Trial name
- NCT03652103
- Testing
- Ultrasound Guided Erector Spinae Plane Block Catheterisation, Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Bozyaka Training and Research Hospital
Soft Tissue Injuries
Effectiveness of Phentolamine Mesylate as a Reversing Agent for Local Anesthesia in Children
Local anaesthesia is considered one of the most alarming and non-comfortable dental procedures for children. This goes back to the persisting effect of the local anaesthesia after finishing dental procedures.
- Trial name
- NCT05448807
- Testing
- OraVerse
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthetics, Local
The Effectiveness of Soft Tissue Vibration in Reducing Pain of Local Anesthesia Injection in Adult Dental Patients
The clinical trial will compare pain perception during dental local anesthesia injections with and without using soft tissue vibration device prior to injection.
- Trial name
- NCT03839134
- Testing
- DentalVibe® Comfort Injection System, Lidocaine Epinephrine
- Where
- Saudi Arabia
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Molar Incisor Hypomineralization, Anesthesia, Local
Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars
The purpose of this randomized, controlled clinical study is to evaluate if application of 38% SDF increases the efficacy of local anesthesia during operative dentistry on permanent molars affected by molar-incisor hypoplasia…
- Trial name
- NCT05964387
- Testing
- SDF
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pain, Patient Satisfaction
Patient-controlled Sedation in Port Implantation (PACSPI-1)
The purpose of this prospective, observational study is to assess the feasibility of patient-controlled sedation (PCS) for implantation of subcutaneous venous ports (SVP).
- Trial name
- PACSPI-1 (NCT04631393)
- Testing
- Propofol Alfentanil
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Stefanie Seifert
Anesthesia
Effects of Systemic or Adjunct Tramadol Addition to Lidocaine Used for IVRA in Patients Undergoing Hand Surgery
Intravenous regional anesthesia (IVRA) is used in outpatient hand surgery as an easily applicable and cost-effective technique with clinical advantages.
- Trial name
- NCT02658721
- Testing
- Lidocaine, lidocaine+adjunct tramadol, lidocaine+systemic tramadol
- Volunteers
- 60 people
- Sponsor
- Bagcilar Training and Research Hospital
Post-operative Pain, Post-cardiac Surgery
Paravertebral Block for Improvement of Quality of Recovery Following Cardiac Surgery
This study aims to evaluate the efficacy of bilateral, paravertebral blockade (intervention) against sham blocks (control) placed prior to sternotomy in improving quality of recovery following cardiac surgery.
- Conditions
- Post-operative Pain, Post-cardiac Surgery, Cardiac Disease
- Trial name
- NCT06008821
- Testing
- Bilateral paravertebral block with 0.25% ropivicaine with 1:400,000 epinephrine
- Where
- Canada
- Volunteers
- 224 people
- Sponsor
- University of British Columbia
Bupivacaine, Anesthetics, Local
Transversus Abdominis Plan Block, Ultrasound or Laparoscopic?
Abdominal wall blocks are frequently used as part of multimodal analgesia for pain control after abdominal surgery. There are studies using the Transversus Abdominis Plane Block for postoperative pain control in laparoscopic…
- Conditions
- Bupivacaine, Anesthetics, Local, Anesthetics, Peripheral Nervous System Agents
- Trial name
- NCT04634721
- Testing
- bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Local Anaesthesia
Intradermal Lidocaine Via MicronJet600 Microneedle Device
The purpose of this study is to determine efficiency and safety of injecting a micro-amount of 2% lidocaine with the commercially available microneedle device MinronJet600 (NanoPass Technologies Ltd, Israel) (registration number…
- Trial name
- NCT05108714
- Testing
- Intravenous cannulation after intradermal injection of lidocaine via MicronJet600 microneedle device (1), Intravenous cannulation after intradermal injection of saline via MicronJet600 microneedle device, Intravenous cannulation after intradermal injection of lidocaine via MicronJet600 microneedle device (2)
- Where
- Russia
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Bariatric Surgery Candidate, Morbid Obesity
Erector Spinae Plane Block Versus Opioid Based General Anesthesia During Laparoscopic Bariatric Surgery
bilateral continuous erector spinae plane blockade may represent a valuable alternatives to thoracіc epidurals analgaesіa in treatment of thoracic neuropathic pain.
- Conditions
- Bariatric Surgery Candidate, Morbid Obesity, Visceral Pain
- Trial name
- NCT03798522
- Testing
- bilateral ultrasound guided erector spinae plane block, Nalbuphine
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Success Rate Under Segmental Epidural, Post Operative Pain
Segmental Epidural Anesthesia (SEA) V/S General Anesthesia for PCNL
Management of nephrolithiasis has been revolutionized by the advent of shock-wave lithotripsy (ESWL) and percutaneous nephrolithotomy (PCNL).
- Trial name
- AnesthesiaPCNL (NCT02878512)
- Testing
- PCNL under General Anesthesia, Segmental Epidural Anesthesia
- Volunteers
- 60 people
- Sponsor
- Maharashtra University of Health Sciences
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