Clinical trials: Locoregional Anaesthesia
Kidney Disease, End-Stage, Kidney Transplant
Comparison of the Effects of General Anesthesia and Combined Spinal-Epidural Anesthesia on Ferroptosis, Humanin and MOTS-c Levels in Renal Transplantation
Renal transplantation is the most effective renal replacement therapy for patients with end-stage renal disease. Ischemia-reperfusion injury may adversely affect graft function and long-term outcomes.
- Conditions
- Kidney Disease, End-Stage, Kidney Transplant, Kidney, Kidney Disease
- Trial name
- NCT07678073
- Testing
- Sevoflurane General Anesthesia, Bupivacaine and Morphine for Combined Spinal-Epidural Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- University of Gaziantep
Crohn's Disease, Inflammatory Bowel Disease
A Comparison of Ultrasound Guided Transversus Abdominis Plane Nerve Block Techniques
Postoperative pain can pose significant challenges in the postoperative recovery of patients undergoing major colorectal surgery. Traditionally, opioids have played an important role in treating postoperative pain.
- Conditions
- Crohn's Disease, Inflammatory Bowel Disease, Postoperative Pain
- Trial name
- NCT02538679
- Testing
- US TAP Bupivacaine/Epinephrine, Lap TAP Bupivacaine/Epinephrine
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Ultrasonographic Evaluation of Epidural Depth in Infants
Evaluation of Skin-to-Epidural Distance at Different Vertebral Levels by Ultrasonography in Infants: A Prospective Observational Study
The goal of this observational study is to learn about the distance between the skin and the epidural space in infants younger than 12 months.
- Trial name
- NCT07847762
- Testing
- Ultrasonographic Assessment of Skin-to-Epidural Distance, Epidural Catheter Placement for Clinical Indications
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Pain After Thoracic Surgery, Coronary Artery Bypass Graft (CABG)
Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block in Postoperative Pain Management After Coronary Artery Bypass Grafting
Coronary Artery Bypass Grafting (CABG) is a common surgical procedure for ischemic heart disease, but it often leads to severe acute and chronic postoperative pain, which can delay recovery and reduce patient comfort.
- Trial name
- NCT07287761
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ankara Education and Research Hospital
Anesthesia
Combination of Serratus Anterior and Pectoral Nerve Blocks (PECS II) as Main Anesthetic Method in Breast Cancer Surgery
Aim of this study is to determine the success of combined serratus anterior and PECS-2 block as the main anesthetic method in breast cancer surgery and also to investigate the patient acceptability of this combination and its…
- Trial name
- NCT05427292
- Testing
- serratus anterior block and PECs II block combination
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Samsun University
Pharmacokinetics, Anesthetics, Local
Bupivacaine Pharmacokinetics in Ultrasound-guided Axillary Brachial Plexus Block.
Introduction: The risk of systemic toxicity when using bupivacaine is a persistent problem, making its pharmacokinetic study crucial to the safety of regional anesthesia (RA).
- Trial name
- NCT02755532
- Testing
- Bupivacaine 0,25%, Bupivacaine 0,5%
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Primary Total Knee Arthroplasty
Dexmedetomidine Intra Venous Arthroplasty
Intravenous dexmedetomidine is a drug used in reanimation with sedative, anxiolytic and sympatholytic properties. Recent studies showed useful properties for anaesthesia : decrease of morphine consumption after a various type of…
- Trial name
- DIVA (NCT03834129)
- Testing
- Dexmedetomidine, sodium chloride 0.9%
- Where
- France
- Volunteers
- 94 people
- Sponsor
- CMC Ambroise Paré
Peripheral Arterial Disease
Impact of Virtual Reality on Patient Pain During Lower Limb Revascularization Via Endovascular Surgery Under Local Anesthesia With Sedation
The prevalence of peripheral arterial disease (PAD) increases with age In addition to medical treatment, endovascular procedures can be performed, depending on the stage of the disease, to prevent complications and/or sequelae…
- Trial name
- REVDOU (NCT07181434)
- Testing
- The patient will be equipped with VR headsets
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Poitiers University Hospital
Anxiety Disorders
Regional Anesthesia / Peripheral Nerve Block and General Anesthesia on Preoperative Anxiety
The researchers aimed to investigate that preoperative anxiety scores of patients who are informed about the anesthesia before surgery with using State-Trait Anxiety Inventory and Amsterdam preoperative anxiety and information…
- Trial name
- NCT02511210
- Testing
- regional anesthesia, general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Cukurova University
NIRS and Anesthesiology
NIRS and Anesthesiology
Our aim in this study is to investigate the effects of the positions applied in Intracranial Surgery on Cerebral Oxygenation(with NIRS device) and to evaluate the superiority of the patient positions used to each other.
- Trial name
- NCT05978310
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Trakya University
Spine Fusion, Locoregional Anaesthesia
PeriOPerative Spine Surgery COntrol Pain (POPSSCOP) Study: Intrathecal Morphine vs Erector Spinae Plane Block for Postoperative Pain Management in Spinal Fusion
This is a prospective observational study conducted at the trauma center of Città della Salute e della Scienza of Turin. The aim of the study is to compare two local regional anesthesia techniques in multimodal analgesia for…
- Conditions
- Spine Fusion, Locoregional Anaesthesia, Intrathecal Anesthesia, Erector Spina Plan Block
- Trial name
- POPSSCOP (NCT07245524)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Regional Anesthesia Techniques in Shoulder Surgery
Effectiveness of Field Block Compared With Interscalene Block in Shoulder Surgery
This study will compare two different types of anesthesia used for shoulder surgery. The first method, called an interscalene block, is commonly performed by anesthesiologists and is effective for pain control but may cause side…
- Trial name
- BLOCK-SHOULDER (NCT07173894)
- Testing
- Shoulder Field Block by Orthopedic Surgeon, Interscalene brachial plexus block and superficial cervical plexus block
- Where
- Israel
- Volunteers
- 64 people
- Sponsor
- Rabin Medical Center
Postoperative Pain, Anesthesia, Local
A Comparison Between a PC and a CC Approach for the Placement of Infraclavicular Perineural Catheters in Hand Surgery
In outpatient hand surgery, 40% of patients report moderate to severe pain within 24 hours of the operation. Effective pain management is therefore essential to ensure a comfortable and safe return home for the patient.
- Trial name
- NCT04960046
- Testing
- Placement of an infraclavicular perineural catheter using a costoclavicular approach, Placement of an infraclavicular perineural catheter by paracoracoid approach
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Describe Novel Approach to Brachial Plexus Anesthesia
The Retroclavicular Approach for Regional Anesthesia
The goal of this study is to demonstrate that the novel retroclavicular approach is a safe, fast and effective technique for ultrasound-guided brachial plexus anesthesia.
- Trial name
- NCT01852396
- Testing
- Retroclavicular block
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Université de Sherbrooke
Balanced Anesthesia, Adjuvants,Anesthesia
The Study of Different Sedative Medications in Monitored Anesthesia Care During Eye Surgery With Local Anesthesia
Due to the delicacy and long duration of the procedure, ophthalmic surgery put forward higher requirements to anesthesia management: 1.
- Trial name
- MAC (NCT04018703)
- Testing
- Dexmedetomidine, Midazolam
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Anesthesia, Adverse Effect
Pharmacokinetics of BPV Following Bilateral US-guided TAP Block for C-section
The transversus abdominis plane block (TAP block) is an effective method of postoperative pain management after cesarean section (C-section).
- Conditions
- Anesthesia, Adverse Effect, Cesarean Section, Transversus Abdominis Plane Block
- Trial name
- NCT03006042
- Testing
- Bupivacaine
- Volunteers
- 17 people
- Sponsor
- University Tunis El Manar
Anesthesia, Local, Anesthesia
Regional Anesthesia in Pediatric Orthopaedic Patients
To identify the benefits from regional anesthesia use as pain management in the pediatric population by delineating the differences in efficacy of continuous nerve blockade versus single-shot techniques after pediatric…
- Conditions
- Anesthesia, Local, Anesthesia, Orthopedic Disorder
- Trial name
- NCT04669145
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ochsner Health System
Proximal Humeral Fracture
Paravertebral Block for Proximal Humeral Fracture Surgery
This study evaluates the effects of T2 paravertebral block block improving interscalene brachial plexus block and superficial cervical plexus block on the relief of pain intensity during elderly proximal humerus fracture fixation…
- Trial name
- NCT03919422
- Testing
- T2 paravertebral block, interscalene brachial plexus block and superficial cervical plexus block
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai 6th People's Hospital
Shoulder Cuff Surgical Repair
Rotator Cuff Repair Under Isolated Loco-regional Anesthesia
Damage to the tendons of the shoulder, called rotator cuff, causes pain and loss of strength that may require surgery. This operation is performed under general anesthesia combined with loco-regional anesthesia of the shoulder.
- Trial name
- AGORA (NCT05848375)
- Testing
- Arthroscopic rotator cuff repair, naropeine or chirocaine (Arthroscopic rotator cuff repair under LRA associated to GA), naropeine or chirocaine (Arthroscopic rotator cuff repair under LRA)
- Where
- 4 sites in France
- Volunteers
- 80 people
- Sponsor
- Elsan
Postoperative Pain, Analgesia
Comparison of Bi-level Erector Spine Plane Block and Combined Pectoral I-II Block in Breast Surgery
In this study, we compared ultrasound-guided modified pectoral nerve (PECS) block and bi level erector spinae plane (ESP) block on postoperative analgesic effect in breast surgery.
- Trial name
- NCT04689581
- Testing
- Ultrasound guided bi-level erector spinae plane block, Ultrasound guided modified pectoral nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kocaeli University
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