Clinical trials: Locoregional Anaesthesia
Procedure, Gynecologic Surgical
Anesthesia on Postoperative Pain After Loop Electrosurgical Excision Procedure
The loop electrosurgical excision procedure (LEEP) is a modified cervical conization that is performed with an electrosurgical loop.
- Trial name
- NCT04984122
- Testing
- LEEP
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Postoperative Pain
Atracurium Mixed With Magnesium Sulfate Versus Atracurium Alone as Adjuvant to Lidocaine in IVRA
The present clinical study will be undertaken to compare study between the effect of atracurium with lidocaine versus addition of magnesium sulphate to the same doses with lidocaine administrated alone in IntraVenous Regional…
- Trial name
- NCT02920905
- Testing
- Lidocaine, atracurium, Mg sulphate
- Where
- 2 sites in Egypt
- Volunteers
- 75 people
- Sponsor
- Assiut University
Airway, Anesthesia, Local
Soft Mist Spray Device for Airway Anaesthesia During Awake Videolaryngoscopy
Rationale: Effective and fast topical anaesthesia of the upper airway is of paramount importance in awake (conscious) videolaryngoscopy of the airway in order to avoid patient discomfort.
- Trial name
- CT2Trachospray (NCT05478122)
- Testing
- Trachospray for awake videolaryngoscopy
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Cleft Palate Children
Length of Hospital Stay and Postoperative Analgesic Requirements After Introduction of a Specific Maxillary Nerve Block in Children Undergoing Cleft Palate Surgery
Cleft lip and palate (CLP) is one of the most common congenital malformations and requires repeated surgical correction during childhood.
- Trial name
- NCT07279883
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Conscious Sedation
Propofol Sedation During Upper Endoscopy With and Without Topical Pharyngeal Anesthesia
It is unclear whether a topical pharyngeal anesthesia adds any benefit to the upper gastrointestinal endoscopy under a propofol sedation.
- Trial name
- NCT01081002
- Testing
- Lidocaine 10%, Diluted gentian root solution
- Where
- 2 sites in Switzerland
- Volunteers
- 294 people
- Sponsor
- University Hospital, Basel, Switzerland
Hip Pain
Comparison of Bacteriostatic Saline to Buffered Lidocaine for Ultrasound Guided Hip Joint Injection Local Anesthesia
The purpose of this study is to compare infiltration pain and anesthetic efficacy between lidocaine and Bacteriostatic saline (BS) for ultrasound (US) guided intraarticular hip injections.
- Trial name
- NCT02209272
- Testing
- bacteriostatic saline, buffered lidocaine
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Respiratory Depression
Effect of Propofol Versus Remimazolam Intravenous Anesthesia on Respiratory Depression
General anesthesia is the preferred choice for pediatric patients, but the induction of volatile anesthetics via face mask may cause preoperative anxiety and postoperative delirium.
- Trial name
- NCT06816173
- Testing
- Propofol group, Remimazolam group
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Pain, Postoperative
Comparing Dexamethasone With Dexmedetomidine as Additives to Bupivacaine in Adductor Canal Block for Knee Arthroscopy.
a comparison shall be conducted between dexamethasone accompanied by bupivacaine, on one hand, and dexmedetomedine accompanied by bupivacaine on the other hand and a control group for pain-free knee arthroscopic surgeries.
- Trial name
- NCT04631822
- Testing
- Spinal anaesthesia, ultrasound-guided Adductor Canal Block + dexamethasone, ultrasound-guided Adductor Canal Block + dexmedetomedine
- Where
- Egypt
- Volunteers
- 135 people
- Sponsor
- Rasha Hamed
Loop Ileostomy, Colorectal Disorders
Quadratus Lumborum Block : Local Anesthesia Versus Placebo
Opioid analgesics have many side effects. Quadratus lumborum (QL) block is one kind of regional nerve block that can reduce the side effects of opioid analgesics.
- Trial name
- NCT03411096
- Testing
- Quadratus lumborum block using ropivacaine, Quadratus lumborum block with normal saline
- Where
- South Korea
- Volunteers
- 57 people
- Sponsor
- Kyungpook National University Hospital
Hypertension
Comparison of Calcium Channel Blockers and Beta Blockers on Tourniquet-induced Hypertension During Intravenous Regional Anesthesia
The investigators aimed to investigate the efficacy of calcium channel blockers and beta blockers for controlling tourniquet induced blood pressure increase in patients undergoing carpal tunnel operations with IVRA.
- Trial name
- NCT02319161
- Testing
- Calcium channel blocker and beta blocker
- Volunteers
- 50 people
- Sponsor
- Ankara University
Dental Anxiety
Comparison of Virtual Reality and Mixed Reality Head-Mounted Displays for Dental Anxiety Control During Local Anesthesia in Children
Dental anxiety is a common problem in children and may negatively affect cooperation, pain perception, and treatment success during dental procedures.
- Trial name
- NCT07398105
- Testing
- Audiovisual Distraction Using Head-Mounted Display
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Nerve Block, Regional Anesthesia
A Retrospective Clinical Registry of Peripheral Nerve Block
Locorregional anaesthesia have been increased its role in different kind of surgeries, alone or combined with general anesthesia.
- Conditions
- Nerve Block, Regional Anesthesia, Postoperative Complications
- Trial name
- NCT04451642
- Testing
- Peripheral nerve block
- Where
- Spain
- Volunteers
- 13,816 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Pain, Forearm Fracture
Pain Alleviation of Forearm Fractures
fractures of upper limb induce much pain . A lot of modalities are available to alleviate pain. fracture hematoma block, and intravenous regional anesthesia seem to be cost effective and attractive options
- Trial name
- NCT03377907
- Testing
- ketamine in hematoma block, ketamine in local intravenous anesthesia, Lidocaine Hydrochloride
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Assiut University
Pain, Postoperative, Anesthesia; Regional
The Pectoral Block for Breast Augmentation Surgery
The pectoral block is a recently developed regional anesthetic technique that can be used for the treatment of postoperative pain after breast surgery.
- Trial name
- BPCAM (NCT03040167)
- Testing
- PEC 1 block, Bupivacaine with epinephrine, Normal saline
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pierre Beaulieu
Postoperative Pain, Total Knee Arthroplasty
Comparing ACB+IPACK and ACB+BiFeS Block Combinations for Analgesia in Total Knee Arthroplasty
Total knee arthroplasty (TKA) is associated with severe postoperative pain that delays mobilization, prolongs hospital stay, and reduces patient satisfaction.
- Trial name
- NCT07561333
- Testing
- ACB+IPACK Group, ACB+BiFeS Group
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Hitit University
Hand Surgery
Music in Wide Awake Hand Surgery
Wide awake local anesthesia no tourniquet (WALANT) surgery has emerged as a popular technique in hand surgery over the last decade.
- Trial name
- NCT04636463
- Testing
- Intraoperative Music
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Hip Surgery, Postoperative Pain Management
Comparison of Intermittent Bolus vs. Continuous Infusion PENG Block for Postoperative Pain in Hip Surgery
This retrospective study evaluates the effects of two different administration methods of the Pericapsular Nerve Group (PENG) Block on postoperative pain control, opioid consumption, and recovery in patients undergoing hip…
- Conditions
- Hip Surgery, Postoperative Pain Management, Pericapsular Nerve Group Block (PENG Block), Regional Anesthesia
- Trial name
- ICPENG (NCT06834243)
- Testing
- Intermittent Bolus PENG Block, Continuous Infusion PENG Block
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Onur Baran
Pain, Postoperative Pain
Comparison of Post-Operative Analgesia After Percutaneous Nephrolithotomy.
The rationale of this study was to compare the efficacy of peri-tract bupivacaine infiltration with intravenous post-operative analgesia following PCNL in reference to the context with the previous studies so that we can adopt…
- Trial name
- NCT04835116
- Testing
- Bupivacaine Hydrochloride 0.25% Injection. Paracetamol 650mg. Orphenadrine 50mg., paracetamol 1000mg. Tramadol 50mg. Dimenhydrinate 50mg.
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Urology, Rawalpindi
Postoperative Pain, Shoulder Arthoscopy
SPSIPB vs CCB in Arthroscopic Shoulder Surgeries
The aim is to compare the postoperative analgesic and hemidiaphragmatic effects of Serratus Posterior Superior Intercostal Plane Block (SPSIPB) versus CostoClavicular Brachial Plexus Block (CCBPB) in patients undergoing…
- Trial name
- NCT07259785
- Testing
- Serratus posterior superior intercostal plane block, Costoclavicular brachial plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Cumhuriyet University
Hip Arthropathy, Regional Anesthesia
The Use of Lumbar Erector Spinae Plane Block for Hip Arthroplasty at the L4 Interspace
Over 300,000 hip arthroplasties are performed each year in the United States.1 This number has been steadily increasing over the last two decades, likely due to increased life expectancy and, more significantly, the obesity…
- Trial name
- NCT03801863
- Testing
- Ultrasound-guided Erector Spinae Plane Block with Ropivacaine 0.375%, Ropivacaine
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
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