Clinical trials: Locoregional Anaesthesia
Hand Injuries With Intravenous Regional Anesthesia
Early Versus Late Deflation of Distal Tourniquet in IVRA With and Without Ketorolac in Hand & Forearm Surgery
Bier block , or intravenous regional anesthesia (IVRA), is a method of anesthesia for upper extremity surgeries. IVRA was first described by August Bier in 1908, and after a period of latency, it began to gain widespread use…
- Trial name
- NCT05234619
- Testing
- Group one ( lidocaine or control LE ) Early deflation, Group two ( lidocaine , ketorolac LKE ) Early deflation, Group three ( lidocaine or control LL ) Late deflation
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pain, Acute, Surgery
ESP Block in VATS: Programmed Intermittent Bolus Versus Continuous Infusion on Quality of Recovery
Fascial plane blocks, such as ESP, rely on the spread of local anaesthetic on an interfacial plane, automated boluses may be particularly useful for this group of blocks.
- Trial name
- NCT05181371
- Testing
- Ultrasound Guided ESP Block with Programmed Intermittent Bolus (PIB) for VATS, Ultrasound Guided ESP Block with Continuous Infusion (CI) for VATS
- Where
- 2 sites in Ireland
- Volunteers
- 60 people
- Sponsor
- Mater Misericordiae University Hospital
Breast Neoplasm
Regional Anesthesia and Partial Mastectomy
Pectoralis nerves plane block (PECS) first described by Blanco in 2011 has become part of postoperative pain management in breast surgery, thoracic surgery and thoracic trauma.
- Trial name
- NCT04824599
- Testing
- PECS II, Local anesthetic infiltration, Subcutaneus local anesthetic infiltration
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Karlstad Central Hospital
Healthy Participants, Tooth Extraction
Application Of Dentapen In Dental Local Infiltration Anesthesia
The goal of this clinical study is to compare patients' self-reported pain and mental stress during infiltration anesthesia between conventional syringe and Dentapen.
- Conditions
- Healthy Participants, Tooth Extraction, Orthodontic Patients
- Trial name
- NCT07431801
- Testing
- computer controlled local anesthesia delivery device (Dentapen), Control
- Where
- Vietnam
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Son Hoang Le
Regional Anesthesia Morbidity, Gallbladder Stone
LaGRA Trial in Laparoscopic Cholecystectomy
This study investigated the effectiveness of a surgeon administered, laparoscopic guided, regional anaesthesia technique.
- Conditions
- Regional Anesthesia Morbidity, Gallbladder Stone, Pain
- Trial name
- LaGRA (NCT03394807)
- Testing
- Levobupivacaine
- Volunteers
- 76 people
- Sponsor
- Health Service Executive, Ireland
Carotid Artery Diseases, Regional Anesthesia
Stress Reduction Using Video Googles on Patients Undergoing Vascular Surgery
One treatment option of internal carotid artery stenosis is open surgical endarterectomy. The operation is frequently carried out under regional plexus anesthesia, allowing the patient to remain awake during the procedure.
- Conditions
- Carotid Artery Diseases, Regional Anesthesia, Distress, Procedural
- Trial name
- MEP-VASC (NCT06704230)
- Testing
- video googles
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Augsburg
Chronic Pain, Acute Pain
Regional Anesthesia for Thyroidectomy
For more than 25 years, Regional Anesthesia has challenged anesthesiologists to determine whether it offers real benefits in terms of patient outcome from major surgery, compared with general anesthesia.
- Trial name
- NCT02108834
- Testing
- nerve block
- Where
- 2 sites in China
- Volunteers
- 79 people
- Sponsor
- Guangzhou First People's Hospital
Anesthesia
Photonic Needle and Paravertebral Space Detection
For effective anesthesia and interventional pain treatments, correct needle placement is crucial. Currently used methods to guide needle placement and confirm the actual treatment location before injection of the medication…
- Trial name
- OTS-PS (NCT01517386)
- Testing
- thoracic surgery
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Philips Healthcare
Regional Anesthesia Morbidity, Pain, Acute
Understanding Rebound Pain After Regional Anesthesia Resolution in Healthy Volunteers
Regional anesthesia decreases postoperative pain scores and opioid consumption, and may prevent chronic pain after surgery in patients undergoing surgery.
- Conditions
- Regional Anesthesia Morbidity, Pain, Acute, Healthy
- Trial name
- NCT06005480
- Testing
- Mepivacaine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Transrectal Systematic Prostate Biopsy Related Pain
A Study on the Pain Control Effect of the Anesthetic Method During Prostate Biopsy: Comparison Between Pelvic Plexus Block and Periprosthetic Nerve Block
This study assesses differences in the effects of pelvic plexus block and periprostatic nerve block among various anesthetic methods that reduce the pain caused by prostate biopsy.
- Trial name
- NCT03681522
- Testing
- Pelvic plexus block, Periprostatic nerve block
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Heart Failure
Dental Anesthesia in Heart Failure Patients
To investigate the occurrence of arrhythmias in dental treatment with local anesthetic.
- Trial name
- DAHFP (NCT02228083)
- Testing
- Lidocaine with epinephrine
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- University of Sao Paulo General Hospital
Hip Fractures
PENG Block vs Fascia Iliaca Block for Emergency Department Analgesia in Hip Fractures
Pain management is a crucial aspect of the care of hip fracture patients. Patients with poorly controlled pain have an increased risk of delirium, long-term functional impairment, and remain hospitalized longer.
- Trial name
- NCT05370586
- Testing
- Pericapsular nerve Group Block, Infrainguinal Fascia Iliaca Block
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Sedative Overdose
Local Anesthesia Impact on Dental Sedation
The goal of this observational study is to investigate the impact of local anesthesia in health children who were sedated for dental procedures.
- Trial name
- NCT06218173
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara University
Anesthesia, Local, Vena Cava Syndrome (Inferior) (Superior)
Changes in Vessels After Peripheral Block
In patients with fluid deficit, vasoconstriction occurs in peripheral tissues and blood circulation is kept in the central area.
- Conditions
- Anesthesia, Local, Vena Cava Syndrome (Inferior) (Superior), Fluid Loss, Postoperative Pain
- Trial name
- NCT05968105
- Testing
- Lateral Sagittal Infraclavicular Block, Inferior vena cava diameter >1.5 cm and Vena Cava Inferior Collapsibility Index (VCI-CI) < 50%, Inferior vena cava diameter <1.5 cm and Vena Cava Inferior Collapsibility Index (VCI-CI) > 50%
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Wound, Anesthesia, Local
To Evaluate Reduction of Pain in Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo.
The purpose of this study is to evaluate if applying a lidocaine topical solution before wounds treatment decreases the pain of the procedure in comparison with placebo solution.
- Trial name
- NCT03676556
- Testing
- Lidocaine, Saline Solution
- Where
- 2 sites in Spain
- Volunteers
- 46 people
- Sponsor
- Hospital Universitari de Bellvitge
Post-operative Pain, Anesthesia, Local
Evaluation of the Analgesic Benefit of Adding the Blocks of the Intermediate and Medial Femoral Cutaneous Nerves in Addition to the Femoral Triangle Block for Postoperative Analgesia After a Knee Replacement Surgery
Total knee replacement surgery can be associated with a significant postoperative pain burden and an inability to mobilize adequately, which can lead to the failure of the ambulatory course.
- Trial name
- NCT06038851
- Testing
- Para-Sartorial Compartments (PACS) Block, Femoral Triangle Block (FTB), Infiltration between popliteal artery and capsule of the knee (IPACK) block
- Where
- Canada
- Volunteers
- 122 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Anesthesia
Efficacy of Injected Local Anesthetic vs Topical Anesthetic in Cosmetic Injectable Fillers.
The purpose of the study is to compare two modalities of local anesthetic administration prior to the placement of cosmetic facial injectable fillers.
- Trial name
- NCT02379221
- Testing
- Injectable, Topical
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Breast Cancer
Regional Anesthesia for Modified Radical Mastectomy With Axillary Lymph Node Dissection
local and regional anesthesia have been introduced with the goal of reducing the side effects associated with general anesthesia and IV opioid analgesia.our hypothesis is that ultrasound-guided interscalene brachial plexus block…
- Trial name
- NCT04239716
- Testing
- regional anesthesia
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Tanta University
COVID-19
Anesthesia Preferences in the COVID-19 Pandemic: General Anesthesia or Regional Anesthesia?
As the COVID-19 pandemic continues, humanity has started to adapt to it. In our study, we aimed to examine the adaptation of anesthetists to the pandemic and its behavioral reflection on their work.
- Trial name
- NCT05531006
- Testing
- retrospective cohort study
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Erol Olcok Corum Training and Research Hospital
Complication of Surgical Procedure, Acute Respiratory Failure, Adult
Prospective Evaluation of a RIsk Score for Postoperative Pulmonary COmPlications in Europe
Prospective Evaluation of a RIsk Score for postoperative pulmonary COmPlications in Europe (PERISCOPE) is a multi-centre, international observational study of a random-sample cohort of patients undergoing a nonobstetric…
- Conditions
- Complication of Surgical Procedure, Acute Respiratory Failure, Adult, Postoperative Respiratory Complications, Pulmonary Failure
- Trial name
- PERISCOPE (NCT01346709)
- Where
- 63 sites in Albania, Belgium and 19 more
- Volunteers
- 5,450 people
- Sponsor
- European Society of Anaesthesiology
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