Clinical trials: Locoregional Anaesthesia
Intertransverse Process Block, External Oblique Intercostal Plane Block
Intertransverse Process Block Versus External Oblique Intercostal Plane Block After Laparoscopic Sleeve Gastrectomy
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Subcostal External Oblique Intercostal Plane Block (EOIPB) in patients undergoing laparoscopic…
- Conditions
- Intertransverse Process Block, External Oblique Intercostal Plane Block, Sleeve Gastrectomy, Regional Anaesthesia
- Trial name
- NCT07591116
- Testing
- Intertransverse Process Block, External Oblique Intercostal Plane Block
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Amputation, Anesthesia, Local
Use of Long-acting Bupivacaine In Lower Extremity Amputation
The purpose of this investigator-initiated study is to assess the use of liposomal bupivacaine in major extremity amputation and its effects on post-operative opioid narcotic use, length of stay, and in-hospital costs.
- Conditions
- Amputation, Anesthesia, Local, Opioid Use
- Trial name
- NCT04360421
- Testing
- Liposomal bupivacaine
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Loma Linda University
Obesity, Regional Anesthesia
Regional Anesthesia and Analgesia Techniques in Obese Patients
Obesity is a health problem throughout the world and has increasingly become a widespread epidemic all over the world and also in Turkey.
- Trial name
- NCT04197752
- Testing
- Regional anesthesia/analgesia techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Istanbul University
Surgery
Diaphragmatic Paralysis After Ultrasound Block of the Suprascapular Nerve for Shoulder Surgery
Shoulder surgery is a source of intense postoperative pain that justifies the use of opioids. In this context, analgesia provided by locoregional anesthesia (ALR) improves the rehabilitation of patients by reducing the length of…
- Trial name
- SSParaDia (NCT03352687)
- Testing
- anterior SSAX, posterior SSAX
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Toulouse
Post Operative Pain, Laparoscopic Surgery
Modified Thoracoabdominal Nerve Block(M-TAPA) in Pediatric Laparoscopic Appendectomies
To compare the effect of M-TAPA block and port-site local anesthetic infiltration on postoperative pain in pediatric laparoscopic appendectomies.
- Conditions
- Post Operative Pain, Laparoscopic Surgery, Pediatrics, Regional Anesthesia
- Trial name
- M-TAPA (NCT06039150)
- Testing
- M-TAPA Block, Local anesthetic infltration to port sites
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Gulhane Training and Research Hospital
Local Anesthesia
Success of Inferior Alveolar Nerve Block in Women Taking Selective Serotonin Reuptake Inhibitors
To evaluate the success of inferior alveolar nerve block (IANB) for mandibular molars with irreversible pulpitis in women under treatment with selective serotonin reuptake inhibitors (SSRIs).
- Trial name
- NCT02884596
- Testing
- selective serotonin reuptake inhibitor
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Isfahan University of Medical Sciences
Carpal Tunnel Syndrome
aDjunct bicarbonatE in Local anaesthesIa for CarpAl Tunnel rElease (DELICATE)
Introduction Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment syndrome in Finland and worldwide. Nowadays carpal tunnel release (CTR) surgery is often done in local anaesthesia.
- Trial name
- DELICATE (NCT05328180)
- Testing
- Sodium bicarbonate, Control arm
- Where
- Finland
- Volunteers
- 116 people
- Sponsor
- Kuopio University Hospital
Anesthesia, Regional, Pain, Postoperative
Pectoral-Intercostal Fascial Plane Block Study
Pain along the sternum following opening of the chest cavity, also known as post-sternotomy pain (PSP), is a common complication after heart surgery that is associated with several negative side effects.
- Trial name
- PIFB (NCT03729635)
- Testing
- Pectoral-intercostal fascial plane block (PIFB)
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anesthetics, Local, Blepharoplasty
Distraction Techniques in Periocular Anesthesia: Tapping vs Vibration
To compare the efficacy of topical tapping vs vibration in lowering pain scores for periocular anesthesia injections.
- Conditions
- Anesthetics, Local, Blepharoplasty, Age-Related Ptosis, Adult
- Trial name
- NCT06355817
- Testing
- Vibration, Tapping
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of Manitoba
Patient With Bronchial Endoscopy
Contribution of Hypnotic Analgesia to Local Anesthesia During Bronchial Endoscopy.
Bronchial endoscopy (or bronchial fibroscopy) is an invasive diagnostic examination performed extremely frequently in the Pneumology department of the Dijon University Hospital, with an average of 1200 procedures per year.
- Trial name
- HypnoFibro (NCT03703960)
- Testing
- hypnotic analgesia, music
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Postoperative Delirium
The Relationship Between Zonulin and Interleukin-8 Levels and Postoperative Delirium Development
The relationship between zonulin and interleukin-8 levels and postoperative delirium development in patients who had femur fracture surgery under regional anesthesia
- Trial name
- ZolDel (NCT04875182)
- Testing
- Evaluation of Delirium development
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Dr. Gokhan Vural
Breast Cancer
Regional Anesthesia for Breast Surgery
Patients scheduled for mastecotmy will be randomized to receive either an ultrasound-guided double space paravertebral block or a PECSII + parasternal block.
- Trial name
- NCT03941223
- Testing
- PECSII and paravertebral blocks
- Where
- Italy
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Educational Problems, Acute Pain
Remote Immersive Virtual Reality Teaching:
Patients in rural Canada face serious anesthesia care deficiencies relative to their counterparts in urban centers. Despite 18% of Canadians living in rural settings only 3.1% of medical specialists practice in rural areas.
- Trial name
- RIVR (NCT05755724)
- Testing
- 3-D Teaching, 2-D Teaching
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Local Anesthetic Toxicity, Regional Anesthesia Morbidity
Ropivacaine Plasma Concentrations After Fascial Blocks in Elective Cardio-thoracic and Abdominal Surgery
Primary aim: observe the incidence of systemic toxicity from local anesthetic (LAST) after performing fascial blocks in patients undergoing elective cardio-thoracic and abdominal surgery.
- Conditions
- Local Anesthetic Toxicity, Regional Anesthesia Morbidity, Postoperative Pain
- Trial name
- NCT05592691
- Testing
- Fascial block
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
Anesthesia, Local
Reversing the Effects of 0.5% Bupivacaine
Clinical trials have shown phentolamine mesylate (PM), brand name OraVerse, to be effective at reducing the amount of time to reversal of local anesthesia with different dental anesthetics.
- Trial name
- NCT02995291
- Testing
- OraVerse, Saline Water (Control)
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Dalhousie University
Hypertension
Chemical Block and Electrical Stimulation of the Carotid Body to Treat Refractory Hypertension
High blood pressure, also referred to as hypertension, affects about 65 million people in the United States alone. Approximately 25 percent of people with hypertension cannot control their high blood pressure, despite the use of…
- Trial name
- NCT02519868
- Testing
- Electrical block, Chemical block
- Where
- Switzerland
- Sponsor
- Eric Albrecht
Pain, Postoperative, Spinal Disease
Comparison of Ultrasound-guided Bilateral ESP Block and Wound Infiltration for Spinal Surgical Analgesia
The aim of our study is to determine the superior procedure in analgesia management by comparing the traditional wound infiltration technique with the ultrasound-guided bilateral erector spina plan block technique in spinal…
- Conditions
- Pain, Postoperative, Spinal Disease, Anesthesia, Local, Anesthesia, Regional
- Trial name
- NCT04642625
- Testing
- Visual Analog Score, patient satisfaction
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Trakya University
Lower Extremity Fracture
Diffusion Length of Local Anesthetics in the Subparaneural Space and Duration of Analgesia
Ultrasound-guided popliteal sciatic nerve block is a widely practiced technique to provide anesthesia or analgesia for below-knee surgeries.
- Trial name
- NCT05437835
- Testing
- Ropivacaine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- General Hospital of Ningxia Medical University
Carotid Artery Stenosis Symptomatic, Carotid Endarterectomy (CEA) Surgical Patients
Correlation Between Carotid Stump Pressure and Interhemispheric rSO₂ Asymmetry During Awake Carotid Endarterectomy
This study aims to better understand how well the brain is perfused (supplied with blood and oxygen) during a specific type of surgery called carotid endarterectomy (CEA), which is performed to prevent strokes in people with…
- Conditions
- Carotid Artery Stenosis Symptomatic, Carotid Endarterectomy (CEA) Surgical Patients, Cerebral Hypoperfusion
- Trial name
- NCT07150260
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir Katip Celebi University
Photobiomodulation Therapy
Reversal of Anaesthesia with Diode Laser
Background: After local anesthesia, which is frequently used in pediatric dentistry, long-term soft tissue numbness can cause various problems.
- Trial name
- NCT06841120
- Testing
- Actual laser application
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
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