Clinical trials: Locoregional Anaesthesia
Pain
A Study to Assess Therapeutic Equivalence Between Test EMLA Patch With Marketed EMLA Patch in Healthy Subjects.
A double-blind, randomized, 2-period, placebo-controlled, single-center, crossover study, efficacy study demonstrating the therapeutic equivalence of the test cellulose disc (matrix) in EMLA patch and the current commercial…
- Trial name
- EMLA (NCT03313336)
- Testing
- EMLA test patch, EMLA current reference patch
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Ipsi- and Contralateral Hypoesthesia
A Human Experimental Model for Neuropathic Pain Using Combined Application of Capsaicin and Local Anesthetics
Main of the present study was to develop a model of concomitant C-fibre block and sensitization eliciting spontaneous pain as well applying topical capsaicin and local anesthetics (LA) to examine the sensory alterations after…
- Trial name
- NCT01540877
- Testing
- Application of capsaicin 0.6%, Application of local anesthetics (EMLA plaster), Application of 1 capsaicin 0.6% and 2. EMLA
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Cesarean Section
Wound Infiltration With Bupivacaine/Adrenalin During Cesarean Section and Postoperative Pain.
Thus study evaluates the advantage of infiltration of the surgical wound by local anesthetics in cesarean section on post operative pain relief.
- Trial name
- NCT03395912
- Testing
- Intervention
- Where
- Israel
- Volunteers
- 288 people
- Sponsor
- HaEmek Medical Center, Israel
Postoperative Pain, Midline Laparotomy
Analgesic Outcomes of Ultrasound-Guided QLB vs TAP Block in Midline Laparotomy
This randomized controlled trial compares the analgesic efficacy of ultrasound-guided bilateral lateral quadratus lumborum block (QLB, QL1) versus ultrasound-guided bilateral transversus abdominis plane (TAP) block in adults…
- Conditions
- Postoperative Pain, Midline Laparotomy, Abdominal Surgery
- Trial name
- NCT07796828
- Testing
- Ultrasound-Guided Lateral Quadratus Lumborum Block (QL1), Ultrasound-Guided Transversus Abdominis Plane Block, Bupivacaine 0.25%
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Sheikh Zayed Medical College
Pain, Postoperative
Block and Periarticular Injection Study
The purpose of the study is to compare two types of perioperative analgesic modalities, adductor canal block plus interspace between popliteal artery and capsule of the knee (IPACK) block and periarticular injection versus…
- Trial name
- NCT06410612
- Testing
- regional anesthesia and PAI, PAI
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- Washington University School of Medicine
Pain, Shoulder Injury
Efficacy of Nerve Blockade Performed Prior to Surgical Intervention Versus Following Surgical Intervention
Nerve blocks, or pain medication injected next to the nerve while patients are asleep, are commonly used for pain management after shoulder surgery and are considered highly effective in decreasing post-operative pain.
- Trial name
- NCT02666118
- Testing
- Preemptive Interscalene Block - Single Shot, Postoperative Interscalene Block- Single Shot, Preemptive Interscalene Block - Catheter
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Complications; Cesarean Section, Hypotension
Extra Sitting Time After Spinal Anesthesia for Cesarean Section and Fetal Well-being
After injection of the spinal anesthetic drug, women will be allowed to lie down immediately (0-30 sec) or after three minutes (180 sec) of sitting.
- Trial name
- NCT02893696
- Testing
- Various sitting time
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Postoperative Pain
Nalbuphine as an Adjuvant to Intravenous Regional Anesthesia
The effect of addition of nalbuphine to lidocaine in intravenous regional anesthesia
- Trial name
- NCT02678585
- Testing
- Nalbuphine, Lidocaine
- Where
- Egypt
- Volunteers
- 106 people
- Sponsor
- Assiut University
Postoperative Pain
EXORA vs ESP Blocks in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is still considered the gold standard for the surgical management of gallbladder disease due to its minimally invasive nature, shorter recovery time, and reduced postoperative complications.
- Trial name
- NCT07187310
- Testing
- EXORA block, Erector Spinae Plane block
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Fayoum University Hospital
Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Influence of Maternal Postioning on Spread of Local Anesthetic After Epidural Analgesia
The purpose of this study is to determine if a lateral positioning of the pregnant woman after epidural analgesia increases the incidence of unilateral functioning epidurals.
- Trial name
- NCT02617823
- Testing
- lateral position
- Where
- 2 sites in Sweden
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- Region Skane
Lignocaine, Anesthesia, Local
Comparison of Pre-procedure Lignocaine Spray Versus Spray-as-you-go for Topical Airway Anesthesia in Flexible Bronchoscopy
Title: Comparing Two Methods of Topical Anesthesia for Fiberoptic Bronchoscopy Purpose: To compare the effectiveness of two methods of anesthesia, pre-procedure lignocaine spray (PPL) and spray-as-you-go (SAYG), in reducing…
- Conditions
- Lignocaine, Anesthesia, Local, Trachea, Airway Disease
- Trial name
- NCT07084623
- Testing
- Pre-procedure lignocaine spray (PPL), Lignocaine Spray (Spray-as-you-go)
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Sheikh Zayed Federal Postgraduate Medical Institute
Scalp Nerve Block, Craniotomy Surgery
The Efficacy of Regional Scalp Block in Craniotomy
The objective of this clinical trial is to evaluate the role of scalp nerve block in craniotomy. The primary questions it seeks to answer are: What are the efficacy and safety profiles of scalp nerve block in craniotomy? The…
- Trial name
- NCT06720285
- Testing
- nerve block with 0.5% ropivacaine, General anesthesia and opioids (fentanyl, propofol, rocuronium)
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Airlangga
Postanesthetic Excitement, Cesarean Section
Dexmedetomidine Compared to Ondansetron for Postanaesthetic Shivering in Patients Undergoing a Cesarean Section
Evaluate the efficiency of management with intravenous dexmedetomidine compared to intravenous ondansetron to achieve the disappearance of post-anesthetic shivering in a shorter time in the obstetric patient undergoing cesarean…
- Trial name
- NCT06289335
- Testing
- saline solution
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Central "Dr. Ignacio Morones Prieto"
Underdosing of Local Anesthetics, Anesthetics, Local
Determination of Minimum Effective Volume of Local Anesthetic in Patients Undergoing Ultrasound-Guided Infraclavicular Approach for Brachial Plexus Blockade
Peripheral nerve blocks with use of USG allowed visualisation of the structures and nerves and made the block administrations safe, quick and comfortable.
- Conditions
- Underdosing of Local Anesthetics, Anesthetics, Local, Peripheral Nervous System Agents, Physiological Effects of Drugs
- Trial name
- NCT03838120
- Testing
- Procedure/Surgery: bupivakain % 0,5
- Volunteers
- 48 people
- Sponsor
- Ankara City Hospital Bilkent
Carpal Tunnel Syndrome
Medical Review: Hand Surgery After Local Block Versus Non-block
In this study, the effects of local block vs non block will be assessed with respect to postoperative outcomes (such as pain score, and recovery profiles) in outpatients after hand surgery.
- Trial name
- NCT01110759
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Cedars-Sinai Medical Center
Quality of Recovery After Mastectomy, Serratus Anterior Plane Block
Timing of Serratus Anterior Plane Block in Mastectomy Surgery
Postoperative pain following mastectomy may adversely affect early mobilization, patient comfort, and overall quality of recovery.
- Conditions
- Quality of Recovery After Mastectomy, Serratus Anterior Plane Block, Postoperative Pain, Mastectomy
- Trial name
- NCT07661212
- Testing
- Ultrasound-Guided Serratus Anterior Plane Block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Atrial Septal Defect, Ventricular Septal Defect
Regional Anesthesia Following Pediatric Cardiac Surgery
The purpose of this study is to evaluate pain control following pediatric cardiac surgery with the use of local anesthesia via an ultrasound guided regional anesthetic technique compared with surgeon delivered wound infiltration.
- Conditions
- Atrial Septal Defect, Ventricular Septal Defect, Pain, Procedural
- Trial name
- NCT05688670
- Testing
- Regional Anesthesia, Wound infiltration, Ropivacaine 0.2% Injectable Solution
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Duke University
Carpal Tunnel Syndrome, Anesthesia, Local
Ultrasound-guided Peripheral Nerve Block Versus Forearm Bier's Block in Patients Undergoing Carpal Tunnel Release
By means of an observer-blinded, randomized controlled trial, the analgesic efficacy of the forearm intravenous regional anesthesia and the ultrasound guided peripheral nerve block will be investigated in patients undergoing…
- Trial name
- NCT03411551
- Testing
- regional anesthesia
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Breast Neoplasms
Regional Anesthesia and Breast Cancer Recurrence
In this multi-center trial, Stage 1-3 patients having mastectomies or isolated lumpectomy with axillary node dissection will be randomly assigned to thoracic epidural or paravertebral anesthesia/analgesia, or to general…
- Trial name
- NCT00418457
- Testing
- General anesthesia and opioids, Regional analgesia and propofol
- Where
- 6 sites in United States, Austria and 4 more
- Volunteers
- 2,108 people
- Sponsor
- The Cleveland Clinic
Labor Pain, Epidural Analgesia for Labour and Delivery
Early Labor Pre-Marking for Epidural Analgesia: Ultrasound vs Manual Palpation
The goal of this clinical trial is to learn if finding and marking the best spot on the back early in labor helps doctors perform epidural pain relief more successfully in pregnant women.
- Conditions
- Labor Pain, Epidural Analgesia for Labour and Delivery, Neuraxial Ultrasound
- Trial name
- NCT07669441
- Testing
- Preprocedural Spinal Ultrasound, Conventional Landmark Palpation
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
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