Clinical trials: Loneliness, open to volunteers
Mild Cognitive Impairment (MCI), Dementia (Diagnosis)
Loneliness as Risk Factor for Dementia
This study aims to determine whether loneliness is associated with a higher incidence of dementia in older adults with a prior diagnosis of mild cognitive impairment after 12 months of follow-up.
- Conditions
- Mild Cognitive Impairment (MCI), Dementia (Diagnosis), Loneliness
- Trial name
- SOLETE (NCT07211945)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Posttraumatic Stress Disorder, Depression
Self-Help Cognitive Processing Therapy (CPT)/Women Veterans Network (WoVeN) Study
Posttraumatic stress disorder (PTSD) can have significant impairment on aspects of mental well-being (MWB) including functioning, loneliness, physical health, and quality of life.
- Trial name
- NCT07250061
- Testing
- Self-Help Cognitive Processing Therapy, Women Veterans Network (WoVeN), Treatment as Usual
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston University
Loneliness, Social Isolation
Need to be Needed (N2BN) Intervention
The proposed study is a randomized, controlled trial (RCT) that will examine the effectiveness of an intervention designed to reduce social isolation and loneliness of adults with serious mental illness (SMI).
- Trial name
- N2BN RCT (NCT06510439)
- Testing
- Need to Be Needed Intervention, Active Control Group
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Temple University
Opioid Use Disorder, Loneliness
Intervening on Opioid Use and Loneliness
This study aims to enroll 300 participants who will be assigned to one of three 3 groups. Each group will receive an intervention lasting 6, weekly sessions of 40-60 minutes.
- Conditions
- Opioid Use Disorder, Loneliness, Social Isolation
- Trial name
- NCT06458335
- Testing
- Cognitive-Behavioral Therapy for Perceived Social Isolation, Health Education
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Rochester
Comfort Theory, AI-Assisted Group Music Intervention
Applying Comfort Theory to an AI-Assisted Group Music Intervention: Psychosocial and Physiological Outcomes and Feasibility in Long-Term Care Residents.
The research design adopts a sequential two-phase framework. The study will be conducted in three residential LTC facilities located in Taichung City or Changhua County, with a total planned enrollment of 60 residents.
- Conditions
- Comfort Theory, AI-Assisted Group Music Intervention, Long-Term Care Residents, Loneliness
- Trial name
- NCT07882979
- Testing
- Group music intervention, AI-assisted monitoring system
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yu Chia Chang
Alzheimer s Disease, Dementia
CommunityRx-Dementia + Peer Navigation (CRxDpeer)
The CRxDpeer intervention, delivered by a trained peer navigator, in practice called a "peer mentor", includes three evidence-based components: (a) focused education about common social (e.g., food and housing insecurity) and…
- Conditions
- Alzheimer s Disease, Dementia, Caregiver, Loneliness
- Trial name
- CRxDpeer (NCT07346183)
- Testing
- CommunityRx-Dpeer
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Perinatal Opioid Use Disorder, Opioid Use Disorder
Adapting the Penny Chatbot for Perinatal OUD Patients: COPILOT
To address both loneliness and engagement in perinatal and OUD care among perinatal women, the investigators plan to adapt an existing texting support chatbot, Penny, to make it appropriate for use by women who are pregnant and…
- Trial name
- PENNY-COPILOT (NCT06969261)
- Testing
- Penny COPILOT
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Major Depressive Disorder, Generalized Anxiety Disorder
Cohort Study on Medical Students' Mental Health
The main objective of this study is to identify risk factors for depression among medical students by comparing them to students who completed their first year but did not enter the medical program (students not accepted into the…
- Conditions
- Major Depressive Disorder, Generalized Anxiety Disorder, Suicidal Ideation, Alcoholism
- Trial name
- OSMOSE (NCT07305701)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Loneliness, Mental Well-being
Creating Encounters Between Generations - Together Instead of Alone (GemsE)
Elderly people and children and young people (CYP) and from families with mentally ill parents are particularly affected by loneliness.
- Conditions
- Loneliness, Mental Well-being, Health-related Quality of Life
- Trial name
- GemsE (NCT07581171)
- Testing
- Mechanisms and effectiveness of intergenerational tandems
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Parkinson Disease, Parkinson Disease, Idiopathic
Step Up to PD: A Community-based Walking Program for People With Parkinson's Disease
This study will investigate the feasibility of a 6-month community walking program for people with Parkinson's disease (PD) and their care partners in greater Saint Louis, Missouri region.
- Trial name
- NCT06859528
- Testing
- Community Walking Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- St. Louis University
Intellectual Disability, Mild to Moderate, Developmental Disability
Comparing the Impact of Peer Support vs. Staff-Delivered Transportation Interventions for Young Adults With Intellectual and Developmental Disabilities.
This clinical trial will look at whether young adults with intellectual and developmental disabilities (YA-IDD) have better outcomes when a travel training intervention called Ready to Ride (R2R) is taught by a specially trained…
- Trial name
- YA-IDD (NCT07505121)
- Testing
- Ready to Ride - Standard Delivery, Ready to Ride - Peer Support Delivery
- Where
- 3 sites in United States
- Volunteers
- 325 people
- Sponsor
- Temple University
Loneliness, Social Support
Activating Social Resources in Psychotherapy-Seeking Individuals: Effectiveness and Timing of a Social Support Just-in-Time Adaptive Intervention
This study evaluates a Just-In-Time Adaptive Intervention (JITAI) aiming to foster social support processes for adults with elevated depressive symptoms awaiting outpatient psychotherapy.
- Conditions
- Loneliness, Social Support, Depressive Symptoms
- Trial name
- NCT07471529
- Testing
- Social Support Just-in-Time Adaptive Intervention
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Zurich
Psychological Distress, Mindfulness Skills
STEPS - Stress Training and Engagement Via Phone-Based Systems
This study will evaluate engagement, usability, and psychological outcomes associated with participation in smartphone-based stress management or mindfulness training program among young adults.
- Conditions
- Psychological Distress, Mindfulness Skills, Usability Satisfaction, Program Engagement
- Trial name
- NCT07639697
- Testing
- Equa, Feature-Enhanced Equa Training Program, Stress Management Training
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Equa Health
Mental Health, Quality of Life
Art Therapy for Enhancing Well-Being in Solitary Older Adults
This study explores the impact of art therapy on mental health and quality of life among solitary older adults. Participants will be randomly assigned to one of two groups: an experimental group receiving art therapy sessions or…
- Conditions
- Mental Health, Quality of Life, Emotional Well-being, Loneliness
- Trial name
- NCT06763757
- Testing
- Art Therapy Program
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Limb Injury, Older Adults
Geriatric Trauma Care Program for Living Alone Older Adults With Injuries
To examine the long-term effects of the Geriatric Trauma Care Program (GTCP) regarding pain, functional disability, depression, loneliness, and health-related quality of life among older adults with traumatic injuries who live…
- Conditions
- Limb Injury, Older Adults, Geriatric, Pain
- Trial name
- NCT06902636
- Testing
- Geriatric trauma care program
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Kaohsiung Medical University
Loneliness
Structured Opportunities for Connection to Improve Aging-related Loneliness
The goal of this early phase clinical trial is to determine the impact of participation in planned social activities among adults 55 years of age or older, who report feelings of loneliness.
- Trial name
- SOCIAL (NCT07708844)
- Testing
- Prescribing of community activities; at least 2 hours per week
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Endeavor Health
Social Isolation, Loneliness
Effectiveness of a Psychological Intervention to Reduce Social Isolation and Promote Social Connectedness in Young Adults
The purpose of this randomized controlled trial is to evaluate the effectiveness of a psychological intervention aimed at reducing social isolation and promoting social connectedness among young adults.
- Conditions
- Social Isolation, Loneliness, Social Skills
- Trial name
- NCT07820020
- Testing
- Digital-Assisted Group Social Skills Training
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Korea University
Loneliness, Grief
The Effects of Psilocybin on Social Connectedness
The study is a randomized, double-blind, placebo-controlled, expectancy-controlled, mechanistic trial. This study looks to explore whether a single dose of psilocybin (25mg) reduces amygdala reactivity to negative socioemotional…
- Trial name
- NCT07693153
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Yale University
Social Isolation
Increasing Veterans' Social Engagement and Connectedness
Social isolation is a negative social determinant of health that affects 1-in-5 adults in the U.S. and 43% of Veterans. Social isolation is estimated to cost the nation $6.7 billion annually in federal healthcare spending.
- Trial name
- CONNECTED (NCT06467214)
- Testing
- CONNECTED, VET BEFRIENDING
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- VA Office of Research and Development
Loneliness, Social Isolation
Fostering Agricultural Relationships and Meaning - Thriving on Kinship
This study aims to enroll 65 participants who will be assigned to one of two groups. Each group will receive an intervention consisting of six weekly sessions of 40-60 minutes each.
- Conditions
- Loneliness, Social Isolation, Rural Health
- Trial name
- (FARM-TOK) (NCT07218965)
- Testing
- Cognitive-Behavioral Therapy for Perceived Social Isolation, Health Education
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Ohio State University