Clinical trials: Long-Haul COVID-19
Covid19, Long COVID
Institut de Recherche Cliniques de Montreal (IRCM) Post-COVID-19 (IPCO) Research Clinic
While many COVID19 studies are focusing on the immediate biological impact of SARS-CoV2 infection, this multidisciplinary research clinic will inform the global community on its recovery phase across patient cohorts with…
- Trial name
- IPCO (NCT04736732)
- Testing
- Medical follow-up
- Where
- Canada
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Emilia Falcone, MD
Post-Acute COVID-19 Syndrome, Biofeedback, Psychology
Prevention of Long Covid Syndrome
Biofeedback equipment is classified by the Food and Drug Administration (FDA) as medical device class II and this type of equipment/treatment has shown evidence regarding stress management in post-Covid-19 syndrome.
- Conditions
- Post-Acute COVID-19 Syndrome, Biofeedback, Psychology, Quality of Life, Depressive Symptoms
- Trial name
- NCT05793736
- Testing
- Biofeedback training, Treatment as usual
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- University of Cagliari
Long COVID
Development of Voice Biomarkers of Frequent COVID-19 and Long Covid-related Symptoms Based on Data From Users of the Long COVID Companion App
The LIH DDP research team focuses its research topics on vocal biomarkers and Long COVID, among others. Voice is indeed a promising tool to monitor health, as it contains many information on our health and is easy to collect.
- Trial name
- EVO-LC (NCT07156994)
- Testing
- No Intervention: Observational Cohort
- Where
- Luxembourg
- Volunteers
- 300 people
- Sponsor
- Luxembourg Institute of Health
Covid19, SARS CoV 2 Infection
COVID-19: A Scope Research on Epidemiology and Clinical Course
Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) 2 infection and the associated coronavirus disease 2019 (COVID-19) are the most recent international health threat challenging our ability to protect populations, to…
- Conditions
- Covid19, SARS CoV 2 Infection, Sequelae of; Infection
- Trial name
- COVID-Scope (NCT05046769)
- Where
- Portugal
- Volunteers
- 5,000 people
- Sponsor
- Instituto de Saude Publica da Universidade do Porto
Long Covid19, Fatigue Syndrome, Chronic
Effects of Cacao Flavonoids in Long COVID-19 Patients (FLALOC)
The study use a triple blind, placebo-controlled design enrolling male and female subjects between 30-70 yo to evaluate the effect of daily consumption of a cacao supplement on inflammation, endothelial damage, handgrip strength…
- Trial name
- FLALOC (NCT06064838)
- Testing
- Flavonoids
- Where
- Mexico
- Volunteers
- 46 people
- Sponsor
- Guillermo Ceballos Reyes
Long-COVID, PASC
Osteopathic Manipulative Therapy Effects on Post-Acute Sequelae of COVID-19 (PASC) or Long COVID
This study is investigating the effects of using an Osteopathic Manipulative Therapy (OMT) treatment protocol that was shown to statistically improve smell in individuals suffering from Long-COVID olfactory (smell) dysfunction in…
- Conditions
- Long-COVID, PASC, Long COVID Syndrome
- Trial name
- NCT06883513
- Testing
- Osteopathic Manipulative Therapy Long-COVID protocol, Osteopathic Manipulative Therapy NOT Long-COVID treatment protocol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Louisville
COVID-19 Pandemic, Diabetes
Study on the Effect of Incentive Spirometer-based Respiratory Training on the Long COVID-19
The COVID-19 pandemic has emerged as the most significant public health crisis of the 21st century. As of the end of January 2023, global confirmed cases have exceeded 670 million, with a domestic cumulative total of 10.24…
- Conditions
- COVID-19 Pandemic, Diabetes, Hypertension, Cardiac Disease
- Trial name
- NCT06231225
- Testing
- Incentive Spirometer respiratory training
- Volunteers
- 100 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Long COVID, Major Depressive Disorder
Presynaptic Imaging in Major Depressive Episodes After COVID-19
The goal of this observational study focuses on understanding and addressing a subset of persistent neuropsychiatric symptoms occurring within 3 months after mild to moderate COVID-19 infection (COVID-DNP).
- Conditions
- Long COVID, Major Depressive Disorder, Major Depressive Episode
- Trial name
- PCOV (NCT06086366)
- Testing
- [11C]DTBZ PET scan, [18F]SDM8 PET scan, MRI scan
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Post-acute Sequelae of COVID-19, Depressive Symptoms
Glutamatergic Modulation as a Treatment for Depressive Symptoms Among Patients With Post-acute Sequelae of COVID (PASC): A Pilot Trial
Post-acute sequelae of SARS-CoV2 (PASC), colloquially known as "long-COVID," is thought to affect between 10-30% of all COVID-19 survivors.
- Conditions
- Post-acute Sequelae of COVID-19, Depressive Symptoms, Cognitive Dysfunction
- Trial name
- NCT05690503
- Testing
- CI-581a, CI-581b
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- New York State Psychiatric Institute
Long COVID
Reliability (Test-retest) of 30 Seconds Sit-to-stand and Timed Up and Go in Adults With Long Covid
The goal of this study is to test the reliability (with a test-retest process) of 30 seconds Sit to Stand and Timed Up and Go in an adult population with long-covid, hospitalised in a rehabilitation center.
- Trial name
- NCT05886842
- Testing
- Test-retest
- Where
- Cyprus
- Volunteers
- 19 people
- Sponsor
- European University Cyprus
Long COVID
The Use of Incentive Spirometry in Adult Patients Hospitalised in a Rehabilitation Center With Long-covid Syndrome
The aim of this clinical trial is to investigate the efficacy of Triflow in the rehabilitation of patients with long covid syndrome hospitalised in a rehabilitation center.
- Trial name
- NCT05813873
- Testing
- Triflow, Control
- Where
- Cyprus
- Volunteers
- 70 people
- Sponsor
- European University Cyprus
Long COVID
Merging Yoga and Self-Management Skills for Symptoms of Long COVID
Long COVID patients experience high symptom burden for many months after initial infection of the COVID-19 virus. This study will investigate a mobile intervention Merging Yoga and Self-Management Skills (MY-Skills Mobile) as a…
- Trial name
- MYS LCOVID-19 (NCT05697042)
- Testing
- MY-Skills for Long COVID
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Colorado, Denver
Long COVID
Study of Xiflam™ Treatment in Patients Post COVID-19 Infection Suffering From What is Known as Long COVID (LC)
The primary objective of this study is to evaluate the safety and efficacy of Xiflam versus Placebo in patients who present with signs and symptoms of Long COVID.
- Trial name
- NCT06437223
- Testing
- Tonabersat
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Inflammx Therapeutics Inc
COVID-19
Fascial Tissue Response to Manual Therapy: Implications in Long COVID-19
According to the World Health Organization (WHO), as of mid-September 2022, more than 21 million Brazilians have recovered from COVID-19.
- Trial name
- NCT06348186
- Testing
- Guidebook, Guidebook and Myofascial Reorganization® (RMF).
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of the State of Santa Catarina
COVID-19
Self-management of Post COVID-19 Syndrome Using Wearable Biometric Technology
The main objective of this pilot study is to evaluate the impact of a self-management intervention using wearable biometric technology on post-COVID-19 syndrome.
- Trial name
- NCT05507190
- Testing
- Self-management of post COVID-19 respiratory outcomes
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Post Acute COVID 19 Syndrome, Memory Impairment
HOBSCOTCH for People With Post Acute COVID-19 Syndrome (PACS)
The goal of this pilot study is to assess the feasibility of adapting and delivering the existing home-based epilepsy self-management intervention, HOBSCOTCH, for people with Post Acute Covid Syndrome (PACS).
- Conditions
- Post Acute COVID 19 Syndrome, Memory Impairment, Memory Dysfunction, Cognitive Dysfunction
- Trial name
- NCT06391489
- Testing
- HOBSCOTCH-PACS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Long COVID
Cognitive Rehabilitation for Long COVID
The investigators are comparing two different methods for helping adults with Long Coronavirus (COVID) also known as Post-Coronavirus Syndrome or Post-Coronavirus Condition manage everyday cognitive challenges.
- Trial name
- STAR-C3 (NCT05676047)
- Testing
- Cognitive Rehabilitation, Education
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Covid 19
Study to Evaluate Benefits & Safety of Endourage Formula C™ Oral Drops in People With Post-Acute COVID-19 Syndrome.
This study will explore the contribution of CBD oral drops in persons experiencing symptoms of Post Acute COVID Syndrome or "PACS".
- Trial name
- "BAC-PAC" (NCT04828668)
- Testing
- Targeted Wellness Formula C™ Sublingual Drops - 1200mg - 30 mL (Formula C)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Endourage, LLC
Long Covid19
Diaphragm Dysfunction After COVID-19 as Determined by Dynamic Chest Radiography
Dynamic chest radiography (DCR) is a rapid and easily performed technique that captures real-time continuous images of the moving chest.
- Trial name
- DD-COVID-19 (NCT06175455)
- Testing
- dynamic chest radiography
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Covid19
Rehabilitation for Patients With Persistent Symptoms Post COVID-19
A large proportion of persons who have had COVID-19 have reported persisted symptoms as fatigue and dyspnea months post infection which affect activities of daily living.
- Trial name
- NCT04836351
- Testing
- Concentrated rehabilitation for patients with persistent symptoms post COVID-19
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Western Norway University of Applied Sciences