Clinical trials: Long-Haul COVID-19
Long COVID-19 Syndrome, Long COVID
Feasibility and Preliminary Efficacy of a Group-based Telerehabilitation Program in People With Post-COVID-19 Sequelae (TEPCO).
The goal of this study pilot randomized controlled study is to evaluate the feasibility of the study procedures and to compare the preliminary efficacy of a rehabilitation program given in a "remote" (telerehabilitation) or…
- Conditions
- Long COVID-19 Syndrome, Long COVID, Long COVID Syndrome
- Trial name
- TEPCO (NCT06952127)
- Testing
- Rehabilitation program
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Centre intégré universitaire de santé et de services sociaux de la Mauricie-et-du-Centre-du-Québec
COVID-19, Pain, Chronic
Pain-related Long Covid in Covid-19 Survivors
The exploratory project aims to investigate the presence of pain as a long Covid-19 symptom in previously hospitalised patients and in non-hospitalised persons previously tested positive in a PCR test.
- Trial name
- NCT05520931
- Testing
- Questionnaire and register-based data assessment
- Where
- Denmark
- Volunteers
- 600,000 people, healthy volunteers welcome
- Sponsor
- Aalborg University
COVID-19, Long COVID
BIO 300 Oral Suspension in Previously Hospitalized Long COVID Patients
This is a randomized, double-blinded, placebo-controlled, two-arm study to evaluate the safety and efficacy of BIO 300 Oral Suspension (BIO 300) as a therapy to improve lung function in patients that were hospitalized for severe…
- Conditions
- COVID-19, Long COVID, Pulmonary Fibrosis, Post-acute Respiratory Complications of COVID-19
- Trial name
- NCT04482595
- Testing
- BIO 300 Oral Suspension
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Humanetics Corporation
COVID-19, Post-COVID-19 Syndrome
The COVID HOME Study: Prospective Cohort Study of Non-hospitalised COVID-19 Patients
Background. Guidelines on COVID-19 management are developed as we learn from this pandemic. However, most research has been done on hospitalised patients and the impact of the disease on non-hospitalised and their role in…
- Trial name
- COVID-HOME (NCT06282627)
- Testing
- Observational study
- Where
- Netherlands
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Covid19
SOLIDARITY Finland Long-COVID (Remdesivir Long-term Follow-up Study of COVID Patients)
SOLIDARITY Finland Long-COVID trial assesses the effects of remdesivir + standard of care (SoC) vs. only SoC on long-COVID symptoms and quality of life (QoL) using questionnaires at one and two years post-discharge.
- Trial name
- NCT04978259
- Testing
- Remdesivir
- Where
- Finland
- Volunteers
- 202 people
- Sponsor
- Clinical Urology and Epidemiology Working Group
Long Covid
Long COVID Ultrasound Trial
The research objective is to assess the safety and potential efficacy of spleen ultrasound stimulation as an intervention for Long COVID in a pilot study.
- Trial name
- LOCUS (NCT06189066)
- Testing
- Splenic Ultrasound
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- SecondWave Systems Inc.
Post Acute COVID-19 Syndrome, Long COVID
Safety, Tolerability and Efficacy of S-1226 in Post-COVID-19 Subjects With Persistent Respiratory Symptoms.
This is a randomized (1:1) , placebo-controlled phase II study to evaluate the safety, tolerability and efficacy of S-1226 in Post-COVID-19 subjects (n≤48) with persistent respiratory symptoms.
- Conditions
- Post Acute COVID-19 Syndrome, Long COVID, COVID-19 Respiratory Infection
- Trial name
- NCT04949386
- Testing
- S-1226 (8%)
- Volunteers
- 48 people
- Sponsor
- SolAeroMed Inc.
Covid19
Post Acute COVID-19 Quality of Life (PAC-19QoL) Tool Development and Patient Registry (PAC-19QoLReg)
Coronavirus Disease 2019 (COVID-19) is a newly emerged disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Trial name
- NCT04586413
- Testing
- No intervention - quality of life measure
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Medialis Ltd.
Stroke, Mild Cognitive Impairment
Telerehabilitation of Balance Clinical and Economic Decision Support System
This study follows the successfully completed HOLOBalance project which was funded by the EU Horizon 2020 scheme. TheHOLOBalance platform delivers exercises demonstrated via a hologram of the physiotherapist and corrected in real…
- Conditions
- Stroke, Mild Cognitive Impairment, Vestibular Diseases, Long Covid19
- Trial name
- TeleRehab DSS (NCT06534164)
- Testing
- Full/High Tech Telerehabilitation decision support system, Basic/Low Tech Telerehabilitation decision support system, OTAGO Home exercise program
- Where
- 5 sites in Germany, Greece and 3 more
- Volunteers
- 460 people
- Sponsor
- University College, London
Fatigue, Post-Acute COVID-19 Syndrome
Immunoadsorption vs. Sham Treatment in Post COVID-19 Patients With Chronic Fatigue Syndrome
The complex clinical symptoms of post COVID syndrome, especially chronic fatigue, pose a major challenge to patients and to the health care system and are frequently refractory to therapeutic intervention.
- Trial name
- NCT05954325
- Where
- Germany
- Volunteers
- 63 people
- Sponsor
- Hannover Medical School
Post-Acute COVID-19 Syndrome
Second Prospective Cohort of Patients Entering the Multidisciplinary Care Pathway for Post-Covid Syndromes - SyPoCo2 Cohort
The study aims to identify clinical profiles of long-COVID patients and correlate them with immunological and molecular data in order to identify prognostic biomarkers and potential therapeutic targets.
- Trial name
- SYPOCO 2 (NCT07356570)
- Testing
- Blood sample collection
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- Hospices Civils de Lyon
COVID-19
Randomised Study to Investigate the Effectiveness of Acupuncture for the Relief of Long COVID-19 Related Fatigue
The Covid pandemic has left us with a significant number of people suffering from Long COVID, which is a clinical diagnosis of significant and varying ongoing symptoms at least 12 weeks following COVID-19 infection and…
- Trial name
- ACU-COVID (NCT05212688)
- Testing
- Acupuncture, Active Control
- Where
- United Kingdom
- Volunteers
- 119 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Post-acute COVID-19 Syndrome, Long-COVID
Sociodemographic, Clinical, Quality of Life and Health Care Conditions in COVID-19 Survivors.
Sociodemographic, Clinical, Quality of Life, and Health Care Conditions After Hospital Discharge in Patients Who Required Admission to the Intensive Care Unit for COVID-19 at the Hospital Universitario Nacional Between April 2020…
- Conditions
- Post-acute COVID-19 Syndrome, Long-COVID, COVID-19, Long COVID
- Trial name
- NCT05185674
- Testing
- Exposure: Coronavirus disease 2019 (COVID-19)
- Where
- Colombia
- Volunteers
- 114 people
- Sponsor
- Javier Eslava
Post-COVID-19 Syndrome
Telerehabilitation in the Post-COVID-19 Patient (TRIALS)
A major issue brought about by the current pandemic concerns the discontinuation of a large proportion of outpatient services provided locally, especially in the rehabilitation field.
- Trial name
- NCT05739552
- Testing
- Telerehabilitation program
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 30 people
- Sponsor
- Istituto Auxologico Italiano
Post-acute Infectious Syndrome (PAIS), Post-COVID 19 Condition (PCC or Long COVID)
CD19-B Cell Depletion in PAIS-ME/CFS Patients
Post-acute infection syndromes (PAIS) are long-lasting health problems that can develop after an infection. They include post-COVID-19 syndrome and similar illnesses following other infections.
- Conditions
- Post-acute Infectious Syndrome (PAIS), Post-COVID 19 Condition (PCC or Long COVID), Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
- Trial name
- PIONEER_PAIS (NCT07724834)
- Testing
- Inebilizumab
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Charite University, Berlin, Germany
Post Acute COVID-19 Syndrome
Effects of Immulina TM Supplements With PASC Patients
This is a multi-site study that will try to determine the effects of Immulina ™, a natural dietary supplement, on blood chemicals associated with inflammation that are often increased in patients with long COVID (also called…
- Trial name
- NCT05524532
- Testing
- Immulina TM
- Where
- 9 sites in United States, Puerto Rico
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Long COVID
Heat thErapy And mobiLity in COVID-19 Survivors
Post-acute sequelae of SARS-CoV-2 infection (PASC) is becoming a major risk factor for chronic diseases, with older adults and those with underlying health conditions at risk of developing persistent mobility limitations and…
- Trial name
- HEAL (NCT06928116)
- Testing
- Heat therapy, Walking
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Nebraska
Covid19, Post-COVID-19 Syndrome
Rehabilitation for Post-COVID-19 Syndrome Through a Supervised Exercise Intervention
This is a randomized controlled trial of the efficacy of a tailored exercise program, based on multicomponent exercise training and/or inspiratory muscle training, compared to the WHO self-management leaflet commonly used in…
- Trial name
- RECOVE (NCT04718506)
- Testing
- Exercise, Inspiratory muscle training, Controls
- Where
- Spain
- Volunteers
- 83 people
- Sponsor
- Universidad de Murcia
Long COVID
Nutritional Management of Post COVID-19 Cognitive Symptoms
The goal of this clinical trial is to learn about in brain "fog" complaints associated with long-COVID in people aged 22-50-years.
- Trial name
- NCT05705648
- Testing
- medium chain triglyceride oil, Safflower oil
- Where
- Canada
- Volunteers
- 103 people
- Sponsor
- University of Alberta
COVID-19
Pulmonary Rehabilitation Post-COVID-19
The main objective of this pilot study was to evaluate the feasibility, safety, and satisfaction of a remote interdisciplinary PR program delivered using two exercise approaches (video conference and self-directed) on the…
- Trial name
- NCT05003271
- Testing
- Exercise program (virtual/remote)
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba