Clinical trials: Long-Term Care
Acute Kidney Injury
Epidemiology and Long Term Outcome of Critically Ill Patients Requiring Renal Replacement Therapy in Southeast Asia and India (InSEA-RRT Registry)
Acute kidney injury is associated with increased short-term and long-term morbidity and mortality. Long-term data is lacking in low to middle-income countries.
- Trial name
- InSEA-RRT (NCT03727997)
- Where
- Thailand
- Volunteers
- 2,315 people
- Sponsor
- Chulalongkorn University
Sleep Quality
Effects of Different Footbath Immersion Depths on Sleep Quality Among Older Adults in Long-Term Care Facilities
Sleep disturbances are common among older adults residing in long-term care facilities. Warm-water footbaths may help improve sleep quality; however, different immersion depths may affect the body's response to warming.
- Trial name
- NCT07892560
- Testing
- Ankle-Level Warm-Water Footbath, Below-Knee Warm-Water Footbath
- Where
- 6 sites in Taiwan
- Volunteers
- 40 people
- Sponsor
- Cai-Syuan Jiang
Deafness; Perception, Bilateral
Feasibility of Remote Cochlear Implant Users' Follow-up
Cochlear implants (CIs) are medical devices now widely used in persons with severe to profound hearing loss. After a six month to one-year period following implantation, adults typically reach optimal fitting parameters, which…
- Trial name
- TELERIC1 (NCT03022227)
- Testing
- telemedicine
- Volunteers
- 30 people
- Sponsor
- Hôpital Rothschild
Ulcerative Colitis
Strategies in Maintenance for Patients Receiving Long-term Therapy (S.I.M.P.L.E.) With MMX (Multi-Matrix System) Mesalamine for Ulcerative Colitis (UC)
To evaluate the percentage of subjects with clinical recurrence of UC at 6 months using MMX mesalamine once daily.
- Trial name
- NCT00446849
- Testing
- MMX Mesalamine
- Where
- 62 sites in United States
- Volunteers
- 290 people
- Sponsor
- Shire
Chronic Illness
"Sport on Prescription" in Primary Care for Patients With Long-term Illnesses
Adapted Physical Activity (APA) helps to prevent chronic diseases identified as major causes of mortality, particularly cardiovascular diseases and some cancers, according to the World Health Organization (WHO).
- Trial name
- PRIMAPA-VAR (NCT05437978)
- Testing
- "Cap Sport Santé 83" program
- Where
- France
- Volunteers
- 127 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Drug Addiction, Employment
Long-Term Treatment of Opioid Use Disorder
Poverty and opioid addiction are interrelated and chronic problems which have not been addressed adequately. The Therapeutic Workplace could treat the many adults with opioid use disorder who are unemployed and live in poverty.
- Trial name
- NCT05534815
- Testing
- Employment-based abstinence reinforcement
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Northern Michigan University
Obesity
Evaluating the Effectiveness of a Stepped-Care Approach to Long-Term Weight Loss (The Step-Up Study)
The number of overweight and obese adults in the United States is increasing at a rapid rate. A "stepped-care" weight loss program, which at key times increases the frequency of contact between an individual trying to lose weight…
- Trial name
- Step-Up (NCT00714168)
- Testing
- Standard Behavioral Weight Loss Program, Stepped-Care Weight Loss Program
- Where
- 2 sites in United States
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Panic Disorder, Agoraphobia
Treatment of Panic Disorder: Long Term Strategies
Cognitive behavior therapy (CBT) with or without medication has been used in the treatment of panic disorder (PD). The purpose of this study is 1) to determine whether nine months of maintenance cognitive-behavior therapy (CBT)…
- Trial name
- NCT00000368
- Testing
- Cognitive behavior therapy, Paroxetine or other medication - algorithm used
- Where
- 4 sites in United States
- Volunteers
- 379 people
- Sponsor
- New York State Psychiatric Institute
Chronic Obstructive Pulmonary Disease (COPD)
A Study of in Elderly Patients With COPD on Long-term Home Oxygen Therapy Combined With MCI
The goal of this clinical trial is to learn The effects of a health education programme based on BCW theory on elderly patients with chronic obstructive pulmonary disease and mild cognitive impairment The main questions it aims…
- Trial name
- COPD、MCI (NCT06852716)
- Testing
- Health education based on BCW theory, Routine health education
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Yuanjiao Yan
Schizophrenia
Long-Term Exercise Training Therapy Versus Usual Care in Patients With Schizophrenia
Patients with schizophrenia have disabling symptoms and cognitive deficits that limit motivation, drive, social- and occupational performance, quality of life and self-efficacy.
- Trial name
- LEXUS (NCT02743143)
- Testing
- Exercise therapy, Follow-up care as usual
- Where
- Norway
- Volunteers
- 48 people
- Sponsor
- St. Olavs Hospital
Loneliness
Reducing Loneliness of Older Adults in Long Term Care Facilities Through Collaborative Augmented Realities
The goal of this clinical trial is to test the use of head-mounted display (HMD) augmented reality (AR) in older adults residing in communities or assisted care facilities.
- Trial name
- NCT06179225
- Testing
- HMD AR, 2-D AV
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Arthritis,Rheumatoid
Long Term Effects of an Early Response to Certolizumab Pegol (CZP, Cimzia®) in Rheumatoid Arthritis (RA) Patients
To determine if early clinical response at 12 weeks to Certolizumab Pegol (CZP, Cimzia ®) therapy in adult Rheumatoid Arthritis (RA) patients is a predictor of better long term clinical response at 18 months compared with a lack…
- Trial name
- RA-PROACTIVE (NCT01288287)
- Where
- 22 sites in Ireland, United Kingdom
- Volunteers
- 149 people
- Sponsor
- UCB Pharma
Pulmonary Disease, Chronic Obstructive
Measure of the Long Term Influence of SPIRIVA® in Acute Respiratory Disorders
The objectives of this study were to evaluate the effect of a one-year treatment with inhaled tiotropium bromide 18 mcg once daily on lung function, incidence and severity of exacerbations in patients with chronic obstructive…
- Trial name
- NCT00274014
- Testing
- Tiotropium
- Where
- 55 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Boehringer Ingelheim
Hip Fractures, Osteoporosis
Secondary Prevention of Osteoporotic Fractures in Residents of Long-Term Care Facilities
Osteoporotic fractures of the hip are a major cause of admission to long-term care facilities. Such fractures put patients at high risk for further fractures, pain and disability.
- Trial name
- NCT00280943
- Testing
- Long-term care facilities in the intervention arm will receive education and feedback audit on performance
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Duke University
Pain, Peripheral Neuropathy
A Study to Determine the Maintenance of Effect After Long-term Treatment of Sativex® in Subjects With Neuropathic Pain
The purpose of this study is to assess the maintenance of effect after long-term treatment of Sativex® in subjects with neuropathic pain.
- Trial name
- NCT00713817
- Testing
- Sativex®
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- Jazz Pharmaceuticals
Schizophrenia
Pragmatic RCT Comparing Aripiprazole, Olanzapine and Haloperidol in the Treatment of Schizophrenia
The GiSAS study is a multi-centre randomized clinical trial that will involve about 80 italian community psychiatric services in Italy and will recruit 800 patients affected by schizophrenia.
- Trial name
- GiSAS (NCT01052389)
- Testing
- Aripiprazole, Olanzapine, Haloperidol
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Pulmonary Arterial Hypertension
Safety and Efficacy of BIA 5-1058 in PAH
This study aims to assess the safety and tolerability of the individual highest tolerated zamicastat doses, achieved in the study BIA-51058-201, during long-term treatment in Pulmonary Arterial Hypertension (PAH) disease.
- Trial name
- NCT06009185
- Testing
- Oral zamicastat
- Where
- 11 sites in Austria, Germany and 4 more
- Volunteers
- 20 people
- Sponsor
- Bial - Portela C S.A.
Pulmonary Disease, Chronic Obstructive
Airway Limitation Study: Study In Primary Care Centers Of Chronic Bronchitis In Long-Term Cigarette Smokers Of At Least 40 Years Of Age With Symptoms Of Cough And Shortness Of Breath
The study does not involve testing of a drug (no treatment intervention). The study will will use spirometry (breathing tests) in subjects of 40 years of age and older with a history of cigarette smoking with chronic bronchitis…
- Trial name
- NCT00442468
- Testing
- Non-interventional study.
- Where
- 47 sites in United States
- Volunteers
- 1,283 people
- Sponsor
- GlaxoSmithKline
Geriatrics, Trauma Injury
Patient Experience of Older Adults Living Alone With Injuries
This study aims to explore the patient experiences of living alone older adults with injuries, and to examine the effects of a "Geriatric Trauma Care Program" in older adults with limb injuries who live alone.
- Conditions
- Geriatrics, Trauma Injury, Living Alone
- Trial name
- NCT07610161
- Testing
- Geriatric Trauma Care Program
- Where
- 2 sites in Taiwan
- Volunteers
- 110 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Schizophrenia, Schizoaffective Disorder
Quetiapine vs Haloperidol Decanoate for the Long Term Treatment of Schizophrenia and Schizoaffective Disorder
The purpose of this research study is to determine whether a new drug for schizophrenia is better for the maintenance treatment than a standard drugs currently prescribed.
- Trial name
- NCT00018642
- Testing
- quetiapine, haloperidol decanoate
- Where
- United States
- Sponsor
- US Department of Veterans Affairs