Clinical trials: Long-term Care
Panic Disorder, Agoraphobia
Long Term Treatment of Panic Disorder With Clonazepam or Paroxetine
The purpose of this study was to determine whether clonazepam and paroxetine are effective in the treatment of panic disorder. Efficacy was evaluated in short-term, long-term and post-treatment.
- Trial name
- LTTPANIC (NCT02852577)
- Testing
- Clonazepam, Paroxetine
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Flu
FLUAD vs. FLUZONE HD Influenza Vaccine in Residents of Long Term Care
Adjuvanted flu vaccine, Fluad, is not immunologically inferior to HD influenza vaccine in older persons living in long-term care.
- Trial name
- NCT03694808
- Testing
- Fluad Vaccine, Fluzone HD Vaccine
- Where
- 2 sites in United States
- Volunteers
- 478 people
- Sponsor
- David H. Canaday
Schizophrenia, Schizoaffective Disorder
An Efficacy and Safety Study of Long-Term Risperidone Microspheres in Participants With Schizophrenia
The purpose of this study is to evaluate the long-term efficacy and safety of a long-acting injectable formulation of risperidone (an antipsychotic medication) and its influence on quality of life, in participants with…
- Trial name
- NCT00269919
- Testing
- Risperidone Long-Acting Injectable (RLAI)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Janssen Korea, Ltd., Korea
Chronic Kidney Disease, Type 1 Diabetes Mellitus
A Study to Learn How Well the Study Treatment Finerenone Works and How Safe it is in People With Long-term Decrease in the Kidneys' Ability to Work Properly (Chronic Kidney Disease) Together With Type 1 Diabetes
Researchers are looking for a better way to treat people with chronic kidney disease (CKD), a progressive decrease in the kidneys' ability to work properly, and type 1 diabetes.
- Trial name
- FINE-ONE (NCT05901831)
- Testing
- Finerenone
- Where
- 79 sites in United States, Canada and 7 more
- Volunteers
- 242 people
- Sponsor
- Bayer
Cancer
Care of Cancer Patients With Bowel Injury Caused by Radiation Therapy to the Pelvis
RATIONALE: A step-by-step procedure may help health care practitioners diagnose and treat cancer patients with bowel injury symptoms caused by radiation therapy.
- Trial name
- NCT00737230
- Testing
- educational intervention, questionnaire administration, assessment of therapy complications
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Phantom Limb Pain
Long-term Effects of Transcranial Direct Current Stimulation (tDCS) on Patients With Phantom Limb Pain (PLP)
Phantom limb pain (PLP) refers to pain in a limb that has been amputated or deafferented. Phantom limb pain might be related to brain cortical plastic changes.
- Trial name
- NCT02051959
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Sheba Medical Center
Schizophrenia
A Long-Term, Open-Label, Study on Schizophrenia
The primary purpose of the study is to help answer the following research questions: How LY 2140023 can be tolerated by patients with Schizophrenia compared to standard of care treatment in 52 weeks time period.
- Trial name
- NCT01129674
- Testing
- LY2140023, Olanzapine, Aripiprazole
- Where
- 81 sites in United States, Croatia and 7 more
- Volunteers
- 560 people
- Sponsor
- Denovo Biopharma LLC
Caregiver, Disabled Veterans
Helping Invested Families Improve Veterans Experiences Study
The purpose of this study is to evaluate a caregiver skill training program (HI-FIVES), offered as a part of a randomized control trial to caregivers of Veterans referred to home and community-based long-term care.
- Conditions
- Caregiver, Disabled Veterans, Referred to Long-term Care, Residing at Home
- Trial name
- HI-FIVES (NCT01777490)
- Testing
- Helping Invested Families Improve Veterans Experiences - Control, Helping Invested Families Improve Veterans Experiences - HI FIVES
- Where
- United States
- Volunteers
- 484 people
- Sponsor
- VA Office of Research and Development
Frail Elderly Syndrome
Implementing, Evaluating, and Scaling Up of the Strengthening a Palliative Approach in Long Term Care (SPA-LTC) Program
This study will evaluate the implementation of the Strengthening a Palliative Approach in Long-Term Care (SPA-LTC) program using a cross-jurisdictional, effectiveness-implementation type II hybrid design (dual testing of clinical…
- Trial name
- NCT03935997
- Testing
- Strengthening a Palliative Approach in Long-Term Care (SPA-LTC) Program
- Where
- 4 sites in Canada
- Volunteers
- 594 people
- Sponsor
- McMaster University
Premature - Weight 1000g-2499g or Gestation of 28-37weeks, Premature Baby 26 to 32 Weeks
Comparison of Two Early Treatments for Premature Babies and Their Effects Over Time
According to the latest World Health Organization report, prematurity is a major health issue, recognized as a significant vulnerability factor contributing to the emergence of neurodevelopmental disorders.
- Conditions
- Premature - Weight 1000g-2499g or Gestation of 28-37weeks, Premature Baby 26 to 32 Weeks, Premature Baby 33 to 36 Weeks, Premature Between 32 and 36 Weeks of Amenorrhoea
- Trial name
- PREMOTSENS (NCT07261046)
- Testing
- ATVV (Auditory, Tactile, Visual and Vestibular stimulation), Singing
- Where
- 2 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Elsan
Risk Reduction Behavior
The Total Health Study
This study is a randomized, controlled, multiple risk intervention pilot study evaluated with clients recruited from VA Medical Center Substance Abuse Programs.
- Trial name
- NCT01415206
- Testing
- Extended Staging Health Risk Intervention (S-HRI), Usual Care
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Old Age, Long Term Care Facility
Co-producing a Novel Model an Outcome Framework for the Implementation of Falls Management in Care Home Settings.
AIM: To co-produce a novel model for implementation of falls management for older people living in care homes SECONDARY OBJECTIVES Component One Objectives: Primary :To co-produce a novel model for the implementation of falls…
- Conditions
- Old Age, Long Term Care Facility, Fall Prevention
- Trial name
- CHAFFINCH (NCT06947915)
- Testing
- Co-design workshop, Survey, Interview
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- University of Nottingham
COVID-19
Treatment of COVID-19 Patients With Anti-interleukin Drugs
The purpose of this study is to test the safety and effectiveness of individually or simultaneously blocking IL-6 and IL-1 versus standard of care on blood oxygenation and systemic cytokine release syndrome in patients with…
- Trial name
- COV-AID (NCT04330638)
- Testing
- Usual Care, Anakinra, Siltuximab
- Where
- 15 sites in Belgium
- Volunteers
- 342 people
- Sponsor
- University Hospital, Ghent
Long-term Sedation for Mechanical Ventilation, Critically Ill Intensive Care Unit Patients
Remimazolam vs Propofol for Long-Term Sedation in Mechanically Ventilated ICU Patients
This multicenter, randomized, controlled, non-inferiority trial is designed to determine whether remimazolam is non-inferior to propofol for prolonged sedation in adult ICU patients requiring mechanical ventilation for ≥48 hours.
- Trial name
- RePro-ICU (NCT07880548)
- Testing
- Remimazolam group, Propofol group
- Where
- 21 sites in China
- Volunteers
- 274 people
- Sponsor
- Sun Yat-sen University
Dementia
Deprescribing Intervention Among Nursing Home Residents With Major Neurocognitive Disorders
Canadians with neurocognitive disorders often are admitted to nursing homes when their disease reaches an advanced stage. At the end of their life, they may encounter adverse symptoms related to medications they no longer need…
- Trial name
- OptimaMedLTC (NCT05155748)
- Testing
- Continuous education and knowledge exchange
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Dre Edeltraut Kröger
Sickle Cell Disease
Clinical Trial to Study the Safety and Tolerability of Memantin Mepha® in Sickle Cell Disease Patients
Symptomatic sickle cell disease is worldwide the most frequent cause for hereditary hemolytic anemia with recurrent pain crisis.
- Trial name
- MemSID (NCT02615847)
- Testing
- Memantinhydrochlorid
- Where
- Switzerland
- Volunteers
- 9 people
- Sponsor
- University of Zurich
Health Communication
Exploring Telehealth to Deliver Me & My Wishes During Coronavirus-19
Due to Coronavirus-19, we are exploring the plausibility of delivering the Me \& My Wishes intervention via telehealth.
- Trial name
- NCT05037448
- Testing
- Me & My Wishes
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of Utah
Heart Failure
Implementing Standards of Care for Heart Failure Patients in General Practice - A Regional Disease Management Program
Heart failure (HF) is an important health problem. Most chronic HF management occurs in primary care. Although guidelines exist, there is an important implementation gap in current HF care in Belgium.
- Trial name
- NCT04334447
- Testing
- Improved primary care HF diagnostics, Heart Failure education, Structured transitional protocol planning post-discharge care
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- KU Leuven
Polypharmacy
Medication Minimization for Long-term Care Residents
The purpose of this experiment is to test the effect of medication minimization on mortality and hospitalization in long-term care residents.
- Trial name
- WiseMed (NCT01932632)
- Testing
- Medication Minimization
- Where
- 6 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Chronic Hepatitis c, Cirrhosis, Liver
Long Term Interferon for Patients Who Did Not Clear Hepatitis C Virus With Standard Treatment
The HALT-C Trial is a National Institute of Diabetes and Digestive and Kidney Diseases sponsored, randomized clinical trial of long-term use of Peginterferon alfa-2a (pegylated interferon) in patients who failed to respond to…
- Conditions
- Chronic Hepatitis c, Cirrhosis, Liver, Fibrosis, Liver, Hepatic Cirrhosis
- Trial name
- HALT-C (NCT00006164)
- Testing
- Peginterferon alfa-2a + Ribavirin, Peginterferon alfa-2a
- Where
- 11 sites in United States
- Volunteers
- 1,050 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
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