Clinical trials: Long-term Care
Post-traumatic Stress Disorder
Diary for Severe Trauma
Treatment of severe trauma patients includes intensive cares. Both trauma and intensive care may lead to a post-traumatic stress disorder and then to a decreased quality of life.
- Trial name
- Qualitrau (NCT02305303)
- Testing
- Diary
- Where
- France
- Volunteers
- 226 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bipolar Disorder, Depression
Improving Mental Health Outcomes: Building an Adaptive Implementation Strategy
The overarching goal of this study is to build the most cost-effective adaptive implementation intervention involving a site-level implementation intervention strategy: Replicating Effective Programs (REP), and the augmentation…
- Conditions
- Bipolar Disorder, Depression, Mood Disorder
- Trial name
- NCT02151331
- Testing
- External Facilitation, External + Internal Facilitation
- Where
- 2 sites in United States
- Volunteers
- 383 people
- Sponsor
- University of Michigan
Hemodialysis Access, Arteriovenous Fistula
Single-Needle Distal Return for Long-Term Arteriovenous Fistula Care
Background: For millions of people worldwide with kidney failure, a well-functioning vascular access, like an arteriovenous fistula (AVF), is essential for life-sustaining hemodialysis.
- Conditions
- Hemodialysis Access, Arteriovenous Fistula, Arteriovenous Fistula Cannulation, Vascular Access
- Trial name
- NCT07372027
- Testing
- Single-Needle Distal Return (SNDR) Cannulation, Standard Two-Needle AVF Cannulation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Suzhou Municipal Hospital of Anhui Province
Multiple Sclerosis
Pulse ACTH vs. MP for MS
We hypothesize that corticotropin or adrenocorticotrophic hormone (ACTH), administered as Acthar Gel® (MANUFACTURER NAME) is effective in the control of clinical disease activity as a pulse therapy for relapsing-remitting MS when…
- Trial name
- NCT01049451
- Testing
- ACTH, Methylprednisolone
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Southern California
Type 1 Diabetes
Long-Term Treatment Effect of DiaPep277 in Type 1 Diabetes
The study is an open-label extension study, offering patients who participated and completed previous study 901 to continue treatment with DiaPep277 and clinical follow-up, for 2 additional years.
- Trial name
- NCT00644501
- Testing
- DiaPep277
- Where
- 3 sites in Israel
- Volunteers
- 43 people
- Sponsor
- Andromeda Biotech Ltd.
Exergame, Major Neurocognitive Disorder
Intervention Study of an Individualized Exergame Training for People With Major Neurocognitive Disorder
This study evaluates the feasibility of the intervention and the study design.
- Conditions
- Exergame, Major Neurocognitive Disorder, Long-term Care Facility, Nursing Home
- Trial name
- NCT04436315
- Testing
- Motor-cognitive training device, Active control condition
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Davy Vancampfort
Myocardial Infarction
A Study to Evaluate the Impact of Long-term Digital Education vs Standard of Care on LDL-C Levels in Post Myocardial Infarction Patients
The purpose of this study was to demonstrate the impact of digital education on the cardiovascular risk factors in post-Myocardial Infarction patients and to generate evidence for broad implementation of the proposed education…
- Trial name
- DEDUCA-CZ (NCT06548555)
- Testing
- systematic educational intervention
- Where
- 5 sites in Czechia
- Volunteers
- 121 people
- Sponsor
- Novartis Pharmaceuticals
Dyspepsia
Proton Pump Inhibitor Treatment Stop
The purpose of this study is to determine how many chronic users of antisecretory medication can stop after a test for a bacteria associated with peptic ulcer disease. This is evaluated in a discontinuation trial.
- Trial name
- NCT00120315
- Testing
- esomeprazole, Helicobacter pylori c-13 breath test
- Where
- Denmark
- Volunteers
- 171 people
- Sponsor
- Odense University Hospital
Hemophilia A or B
PF-06741086 Long-term Treatment in Severe Hemophilia
This study is designed to evaluate the safety, tolerability and efficacy of long-term treatment with PF-06741086 in subjects with severe hemophilia who participated in the 3-month Phase 1b/2 B7841002 study.
- Trial name
- NCT03363321
- Testing
- PF-06741086
- Where
- 8 sites in United States, Brazil and 5 more
- Volunteers
- 20 people
- Sponsor
- Pfizer
Cancer
Pan Tumor Rollover Study
Main Objective of this study is to examine long-term safety of nivolumab monotherapy including combinations and other cancer therapies in various tumor types.
- Trial name
- NCT03899155
- Testing
- Nivolumab, Ipilimumab, Cabozantinib
- Where
- 410 sites in United States, Argentina and 36 more
- Volunteers
- 1,500 people
- Sponsor
- Bristol-Myers Squibb
Alzheimer's Disease
The Safety and Efficacy of Long-term Treatment of PINS Stimulator System for Patients With Alzheimer's Disease
Purpose: The purpose of this clinical study is to verify the long term effectiveness and safety of a bilateral deep brain stimulation (DBS) produced by Beijing PINS Medical Co., Ltd.
- Trial name
- NCT02253043
- Testing
- Deep Brain Stimulation (Beijing PINS Medical Co., Ltd)
- Where
- 2 sites in China
- Volunteers
- 10 people
- Sponsor
- Beijing Pins Medical Co., Ltd
Anemia, Sickle Cell
Safety of ICL670 vs. Deferoxamine in Sickle Cell Disease Patients With Iron Overload Due to Blood Transfusions
The purpose of this study is to determine if the new orally active iron chelator, ICL670, is as safe as deferoxamine in preventing accumulation of iron in the body while a patient is undergoing repeated blood transfusions.
- Trial name
- NCT00067080
- Testing
- ICL670, deferoxamine
- Where
- 34 sites in United States
- Volunteers
- 195 people
- Sponsor
- Novartis Pharmaceuticals
Psoriasis
Observational Study Evaluating Etanercept (Enbrel®) In Subjects With Plaque-Type Psoriasis In Usual Care Settings
This prospective observational cohort study will assess the average duration of the drug free interval between etanercept treatment cycles in usual care settings in Germany.
- Trial name
- NCT00708708
- Testing
- etanercept (Enbrel®)
- Where
- Germany
- Volunteers
- 926 people
- Sponsor
- Pfizer
Malaria
Early Childhood Malaria Prevention With Maloprim in The Gambia
A trial was conducted in the 1980s to compare two strategies for control of malaria in young children aged 3-59 months: treatment with chloroquine versus treatment combined with fortnightly chemoprophylaxis with Maloprim.
- Trial name
- NCT00294580
- Testing
- Maloprim
- Where
- The Gambia
- Volunteers
- 2,253 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Diabetes Mellitus
Effect of Case-Management Using Home Monitoring on Diabetes and Blood Pressure Outcomes
This is a randomized trial designed to determine if adoption of the chronic care model in conjunction with nurse case management, home telemonitoring, and home HbA1c monitoring can improve glycemic control compared to patients…
- Trial name
- NCT00935441
- Testing
- case management with telemonitoring, usual case management
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Minneapolis Veterans Affairs Medical Center
SARS-CoV-2, Covid19
National Survey Concerning Vaccination Against COVID-19 in Nursing Homes and Long-Term Care Units
The COVID-19 pandemic is a challenge for the French healthcare system, particularly among the elderly due to their particular vulnerability to the serious consequences of the disease, with an estimated mortality rate of around…
- Trial name
- VACOVID-SENIOR (NCT04779541)
- Testing
- observation
- Where
- France
- Volunteers
- 323 people
- Sponsor
- University Hospital, Angers
Growth Hormone Deficiency
A Prospective Non-Interventional Study Protocol With Primary Data Collection - Assessment Of The Long Term Treatment Outcomes Of Genotropin Treatment In Growth Hormone Deficiency (GHD) Patients
The purpose of this study is to assess the long term treatment outcomes of Growth Hormone treatment in patients who are prescribed and treated with Genotropin.
- Trial name
- NCT01947894
- Testing
- Non Interventional Study
- Where
- 12 sites in Sweden
- Volunteers
- 377 people
- Sponsor
- Pfizer
Mental Health Issue
Effects of Mindfulness Based Elder Care (MBEC) on Psychological and Spiritual Well Being
This study aims to verify the effectiveness of the mindfulness-based elder care (MBEC) therapy developed by McBee (2008) in improving the psychological and spiritual well-being of seniors with disabilities living in residential…
- Trial name
- NCT05123261
- Testing
- the mindfulness-based elder care (MBEC) therapy
- Where
- Taiwan
- Volunteers
- 77 people
- Sponsor
- Mackay Medical College
Cardiovascular Disease
Pharmacodynamic Trial, of Slow Release ASA, in Platelet Functionalism, a Long Term Treatment Period
Evaluation of the pharmacodynamic profile (antiaggregant profile, balance of prostanoids and nitric oxid) of a ASA-SR (slow-release)formulation in comparison with a ASA NR (normal release), 150 mg, during 12 months of treatment.
- Trial name
- NCT00501254
- Testing
- Slow release acetyl salicylic acid, Antithrombotic effect
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Rottapharm Spain
Scars Formation, Quality of Life
Long Term Follow up of Scars Formation and Quality of Life Assessment Study
In previous study (MW2004-011-02), patients with burn wounds had their damaged skin removed by either standard of care treatment or by Debrase Gel Dressing (DGD), which is composed of enzymes that dissolve the damaged skin…
- Trial name
- NCT01350700
- Testing
- Scars assessment & QOL
- Where
- Slovakia
- Volunteers
- 148 people
- Sponsor
- MediWound Ltd