Clinical trials: Long-term Health Conditions
Malaria,Falciparum, Malaria
CHILD (Child Health and Infection With Low Density) Malaria
This trial will assess the long-term health and socioeconomic impact of interventions targeting low-density malaria infection (LMI) among children in Tanzania
- Trial name
- NCT05567016
- Testing
- Active case detection using molecular testing (ACDm), Passive case detection using molecular testing (PCDm), Control (standard of care)
- Where
- Tanzania
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Young People With All Long-term Health Conditions
The National Transition Evaluation Study
This is a multi-centre study within England to evaluate whether the Burdett Trust National Transition Network and the implementation of the Model of Improvement for Transition has an impact on the experience of transitioning from…
- Trial name
- NTES (NCT05867745)
- Testing
- Interview, Survey, Letter to a friend (autoethnography)
- Where
- 7 sites in United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Acute Disease, Sepsis
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain of acute care.
- Conditions
- Acute Disease, Sepsis, Pneumonia, Frailty
- Trial name
- Acutelines (NCT04615065)
- Where
- Netherlands
- Volunteers
- 35,000 people
- Sponsor
- University Medical Center Groningen
Pediatric Obesity, Psychosocial Well-being
Childhood Obesity, Decided Not to Participate, Lifestyle Intervention and Psychosocial Well-being.
Childhood obesity has been associated with an increased risk of impaired psychosocial well-being and the development of depression and anxiety.
- Trial name
- NCT06705231
- Testing
- The Aarhus-intervention
- Where
- Denmark
- Volunteers
- 403 people
- Sponsor
- University of Aarhus
Chronic Obstructive Pulmonary Disease (COPD)
A Study of in Elderly Patients With COPD on Long-term Home Oxygen Therapy Combined With MCI
The goal of this clinical trial is to learn The effects of a health education programme based on BCW theory on elderly patients with chronic obstructive pulmonary disease and mild cognitive impairment The main questions it aims…
- Trial name
- COPD、MCI (NCT06852716)
- Testing
- Health education based on BCW theory, Routine health education
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Yuanjiao Yan
Heat Stress, Fatigue
Short- and Long-term Health Consequences of Workers During Consecutive Days of Heat Stress
The purpose of this study is to measure fatigue and indicators of acute kidney injury during consecutive days of work in a hot environment.
- Trial name
- NCT05302674
- Testing
- Hot Dry
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Depression - Major Depressive Disorder, Bipolar
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health (BLOOM) is a project that aims to overcome age and diagnostic boundaries to generate person-specific longitudinal profiles of mental…
- Conditions
- Depression - Major Depressive Disorder, Bipolar, Psychosis, Eating Disorder NOS
- Trial name
- BLOOM (NCT06978452)
- Where
- Canada
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Long-term Health Conditions
An Acceptance and Commitment Therapy Psychoeducation Single Session Intervention on Childhood Anxiety for Carers of Children With a Long-Term Health Condition
The goal of this feasibility study was to assess the acceptability and feasibility of the ACT-based training package for carers of children with a long-term health condition (LTHC) who also experience anxiety.
- Trial name
- NCT07656220
- Testing
- Psychoeducation for anxiety
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of East Anglia
Pulmonary Hypertension, Chronic Obstructive Pulmonary Disease
Two-Part Dose-Confirming Study of Pulsed Inhaled Nitric Oxide in Subjects With WHO Group 3 Pulmonary Hypertension Associated With COPD
This is a placebo-controlled, double-blind, parallel, randomized, two-part, dose-confirming clinical study characterizing the pharmacodynamic effects of pulsed iNO using the combination product, inhaled nitric oxide/INOpulse DS-C…
- Trial name
- NCT01728220
- Testing
- Inhaled NO delivered via INOpulse DS-C Device
- Where
- 43 sites in United States
- Volunteers
- 159 people
- Sponsor
- Bellerophon Pulse Technologies
Diabetes Mellitus, Hypertension
The Long-term Spill-over Impact of COVID-19 on Health and Healthcare of People With Non-communicable Diseases
Objectives and aim: To evaluate the long-term spill-over (indirect) effect of Coronavirus disease (COVID-19) on health outcomes and healthcare utilization among people with non-communicable diseases and without COVID-19.
- Conditions
- Diabetes Mellitus, Hypertension, Cancer, Cardiovascular Diseases
- Trial name
- NCT05248412
- Testing
- COVID-19 outbreaks
- Where
- China
- Volunteers
- 250,000 people
- Sponsor
- The University of Hong Kong
Weight Loss
The Leeds Women's Wellbeing (LWW) Study
The purpose of this parallel design study is to assess the relative effects of two 12-week healthy eating dietary interventions: general healthy eating (Diet A) and general healthy eating combined with advice to increase fibre…
- Trial name
- LWW (NCT01539369)
- Testing
- Healthy eating diet (Diet A) or healthy eating diet combined with advice to increase fibre intake (Diet B) to at least 25g/day
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Chronic Non-Cancer Pain, Opioid Use Disorder
Long-Term Opioid Therapy in Chronic Non-Cancer Pain: Risks and Benefits
The study investigates long-term opioid treatment in patients with chronic non-cancer pain (CNCP). The study aims to prospectively identify predictive factors for work ability and for developing opioid use disorder (according to…
- Trial name
- NCT06063902
- Where
- Sweden
- Volunteers
- 1,000 people
- Sponsor
- Uppsala University
Sarcopenia in Elderly, Rehabilitation Exercise
Effectiveness of Smart-Assisted Rehabilitation Exercise Training on the Physical and Mental Health of Older Adults in Long-Term Care Facilities
The purpose of this clinical trial is to evaluate the effectiveness of a smart-assisted rehabilitation system on the physical and mental health of elderly residents in long-term care facilities through exercise training.
- Conditions
- Sarcopenia in Elderly, Rehabilitation Exercise, Long Term Care
- Trial name
- NCT07197528
- Testing
- Experimental Arm：Smart-assisted rehabilitation exercise system Control Arm：Usual care or routine physical activity
- Where
- Taiwan
- Volunteers
- 42 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Aging, Cognitive Decline
ACHIEVE Brain Health Follow-Up Study
The ACHIEVE Brain Health Follow-Up Study is a 3-year follow-up to the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) randomized study to determine the long-term effect of hearing intervention vs.
- Conditions
- Aging, Cognitive Decline, Mild Cognitive Impairment, Dementia
- Trial name
- ACHIEVE-BHFU (NCT05532657)
- Testing
- Hearing intervention, Successful aging/delayed hearing intervention
- Where
- 4 sites in United States
- Volunteers
- 629 people
- Sponsor
- Johns Hopkins University
Chronic Obstructive Pulmonary Disease
Compliance of Long-term Home Non-invasive Ventilation for Patients With Chronic Obstructive Pulmonary Disease
Background : Long-term home non-invasive ventilation (NIV) can be proposed as treatment for acute respiratory failure with severe alveolar hypoventilation.
- Trial name
- NCT04333901
- Where
- 8 sites in France
- Volunteers
- 25 people
- Sponsor
- Vivisol
Rheumatic Diseases
Reducing Uncertainty Distress in Long Term Health Conditions
The goal of this pilot intervention study is to develop and test a new psychological therapy model in people with long term health conditions (rheumatic conditions) who are experiencing distress (anxiety or low mood) in relation…
- Trial name
- NCT05698251
- Testing
- Uncertainty distress model
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Newcastle University
Chronic Disease
Strategies Empowering Activities in Everyday Life: An Internet-based Occupational Therapy Intervention
The purpose of the study is to evaluate the feasibility, potential outcomes and the implementation process of a second updated version of an internet-based intervention in occupational therapy, focusing on self-management in…
- Trial name
- SEE2:0 (NCT06484322)
- Testing
- Strategies Empowering Activities in Everyday life (SEE 2.0)
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Luleå Tekniska Universitet
Chronic Obstructive Pulmonary Disease
Long-term Impact of Pulmonary Rehabilitation
This study has been designed to capture a large group of patients who undergo pulmonary rehabilitation and map their progression over a 5 year time-frame.
- Trial name
- NCT00959855
- Testing
- Pulmonary Rehabilitation
- Where
- Ireland
- Volunteers
- 120 people
- Sponsor
- Beaumont Hospital
Vaginal Bleeding
Long-Term Outcome Following Laparoscopic Supracervical Hysterectomy Performed With and Without Excision of the Endocervix in a Reverse Cone Pattern
The occurrence of persistent vaginal bleeding following laparoscopic supracervical hysterectomy (LSH) is reported in the wide range of 0 % - 25 %.
- Trial name
- LSH-LAPCONE (NCT00921778)
- Testing
- Lapcone, laparoscopic supracervical hysterectomy
- Where
- Norway
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
COPD
A Prospective Observational Study of the Breath Responsive Variable Bolus Oxygen Conserving Device
Evaluate subjects in an prospective observational study Subjects will be administered scientifically validated questionnaires Evaluate Quality Improvement and Oxygen Utilization Improvements. 1.
- Trial name
- BRVB-OCD (NCT02627599)
- Testing
- Breath Responsive Variable Bolus Oxygen Conserving Device
- Where
- 3 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- StratiHealth