Clinical trials: Long-term Health Conditions
Chronic Myeloid Leukemia
Mid-to Long-Term Outcomes in Chronic Myeloid Leukemia (CML) Patients With Complete Cytogenetic Response After Imatinib as First Line Therapy
Rationale: At present, virtually no evidence exists regarding mid to long-term patient-reported health outcomes (e.g., health related quality of life-HRQOL) of CML patients treated with Imatinib.
- Trial name
- NCT00896129
- Testing
- HRQOL Survey Packet
- Where
- 25 sites in Italy
- Volunteers
- 448 people
- Sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto
Asymptomatic Condition
Long Term Effects of Different Dietary Protocols on Determinants of Health in Patients' Lymphocytes
Food choices and eating habits play an important role in the management of common noncommunicable diseases, i.e. diabetes type II, hypertension, metabolic syndrome and others.
- Trial name
- FTIR (NCT05377164)
- Testing
- food choices
- Where
- Slovenia
- Volunteers
- 12 people
- Sponsor
- University of Primorska
Sleep Disorders
Patient Preference, Sleep Quality, and Anxiety/Depression: A Randomized Comparison of Etravirine and Efavirenz
Efavirenz causes neuropsychiatric side effects and sleep disturbance, including vivid dreams, dizziness, and abnormal tiredness.
- Trial name
- SWITCH-EE (NCT00792584)
- Testing
- etravirine, efavirenz
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Geneva
Cancer, Mental Health
Healthspan Connect Programme of Research
Healthspan Connect is a new research programme designed to understand what helps people stay healthy as they age. The programme will explore how lifestyle, environment, genetics, and social factors influence healthy ageing and…
- Conditions
- Cancer, Mental Health, Ageing Well, Resilience
- Trial name
- NCT07209774
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- King's College London
Chronic Conditions, Multiple, Diseases of the Circulatory System
National Institute for Health and Care Research Global Health Research Centre for Multiple Long-Term Conditions
Multiple Long-Term Conditions (MLTC), defined as the coexistence of two or more chronic conditions, is increasingly prevalent in India.
- Conditions
- Chronic Conditions, Multiple, Diseases of the Circulatory System, Diseases of the Respiratory System, Endocrine, Nutritional and Metabolic Diseases
- Trial name
- NIHR-GHRC MLTC (NCT07582380)
- Testing
- Electronic Decision Support System (EDSS), Assisted Telemedicine, Patient-facing app for self-management, supported by care coordination through Community Champions and Care Coordinators.
- Where
- 120 sites in India, Nepal
- Volunteers
- 3,600 people
- Sponsor
- Centre for Chronic Disease Control, India
Metabolic Health
Effects of Exercise During Pregnancy on the Long-term Metabolic Health of Mothers and Their Offspring
The aim of this study was to assess the long-term metabolic effects of gestational exercise on overweight and obese women and their offspring 8-10 years post-intervention.
- Trial name
- NCT07435857
- Testing
- exercise
- Where
- China
- Volunteers
- 221 people
- Sponsor
- Peking University First Hospital
Chronic Pain
Pain Management Teams Using Whole Health to Optimize Function and Safety in Veterans: The TEAMWORK Trial
The focus of this study is to determine whether adding Whole Health Coaching (WHC) improves pain care among adults with chronic pain and who are currently working with a pain management team (PMT) at the VA.
- Trial name
- TEAMWORK (NCT07149870)
- Testing
- Pain Management Team + Whole Health Coach (PMT-WHC), Pain Management Team-Usual Care (PMT-UC)
- Where
- 5 sites in United States
- Volunteers
- 432 people
- Sponsor
- VA Office of Research and Development
Atrial Fibrillation (AF), Stroke
Population-based Atrial Fibrillation Screening in Individuals With NT-proBNP Above Median in the Tromsø Study
The aim is to investigate whether screening with long-term ECG monitoring in individuals with elevated NT-proBNP leads to a lower incidence of ischeamic stroke and death from vascular causes.
- Conditions
- Atrial Fibrillation (AF), Stroke, NT-pro-BNP, Cognitive Function and Well-Being
- Trial name
- PAFS-Tromsø (NCT07343895)
- Testing
- Long term heart rythm monitoring by ECG247
- Where
- 2 sites in Norway
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Accidental Falls, Muscle Weakness
The Effects of a Walking Program on Balance, Falls and Well Being in Individuals Residing in Long-term Care
The purpose of this study is to assess the effectiveness of a regular walking program (which inevitably involves human interaction) compared to a usual care condition and to a human interaction condition (without the extra…
- Conditions
- Accidental Falls, Muscle Weakness, Gait, Unsteady, Depression
- Trial name
- NCT01277809
- Testing
- Interpersonal Interaction, Walking Program
- Where
- Canada
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Overweight and Obesity
Time-restricted Eating and High-intensity Interval Training for Metabolic Health in Adults With Overweight/Obesity
This study will investigate the effects of 12 months periodised time-restricted eating combined with high-intensity interval training compared with a control group on fat mass in adults with overweight/obesity.
- Trial name
- TREHIIT-3 (NCT07036562)
- Testing
- Time-restricted eating and high-intensity interval training
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian University of Science and Technology
Diabetes Mellitus, Chronic Disease
Patient Activation Through Community Empowerment/Engagement for Diabetes Management (PACE-D)
The study is a non-randomised controlled trial involving an intervention group and a control group. It aims to evaluate the effects of a patient engagement and empowerment model of collaborative care support planning on clinical…
- Conditions
- Diabetes Mellitus, Chronic Disease, Patient Care Planning, Patient Participation
- Trial name
- PACE-D (NCT04288362)
- Testing
- Intervention Group, Control Group
- Where
- Singapore
- Volunteers
- 1,620 people
- Sponsor
- National University Health System, Singapore
Hearing Impaired
Educational Program for Hearing Aid Users With Internet Support
The purpose of this study is to examine the short-term effects of complementing an educational program for hearing aid users with Internet support.
- Trial name
- NCT01837550
- Testing
- Intervention group, Control group
- Where
- Sweden
- Volunteers
- 74 people
- Sponsor
- Sodra Alvsborgs Hospital
Hearing Loss, Conductive, Hearing Loss, Mixed
Pilot Study to Evaluate the Long-term Chronic Care of Patients Who Could or do Utilize an Osseointegrated Device (OID)
The primary objective of the study is to evaluate OID hearing intervention on cognition among patients who could vs. do utilize an OID.
- Conditions
- Hearing Loss, Conductive, Hearing Loss, Mixed, Deafness, Unilateral
- Trial name
- NCT04899037
- Testing
- No intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of South Florida
Heart Failure, Acute Coronary Syndrome
Big Data to Assess the Healthcare and Health Outcomes Burden of Acute Coronary Syndromes Complicated With Heart Failure
The goal of this observational study is to define the incidence of heart failure (HF) after acute coronary syndrome (ACS). The main question it aims to answer is: To define HF incidence in the medium and long-term in the context…
- Conditions
- Heart Failure, Acute Coronary Syndrome, Heart Decompensation, Myocardial Infarction, Acute
- Trial name
- BEAT-HF (NCT06255418)
- Where
- Spain
- Volunteers
- 7,860,560 people
- Sponsor
- Hospital Universitari de Bellvitge
Measles
Non-Specific Effects of Standard Titre Measles Vaccination
The general objectives of the proposed research work are: A1) to reduce childhood mortality in developing countries through better control of measles infection by finding the best immunization strategy, and A2) to investigate the…
- Trial name
- NCT00168662
- Testing
- Measles and inactivated polio vaccine
- Where
- Guinea-Bissau
- Volunteers
- 7,800 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Long Term Adverse Effects, Combat Disorders
Long-term Health Outcomes of AE Casualties
This study involves individuals who are currently participating in the Wounded Warrior Recovery Project and underwent aeromedical evacuation (AE) due to injury during deployment in Iraq or Afghanistan.
- Trial name
- NCT03736356
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Ian Stewart
Coronary Heart Disease, Stroke
Examining the Long-Term Risks of Oophorectomy
At the time of hysterectomy for benign disease, the overall health benefits of preserving ovarian function in a large population of women have not been established.
- Conditions
- Coronary Heart Disease, Stroke, Breast Cancer, Ovarian Cancer
- Trial name
- NCT00655447
- Where
- United States
- Volunteers
- 32,175 people, healthy volunteers welcome
- Sponsor
- Parker, William H., M.D.
Hemophilia A
A Study to Evaluate Impact of Efanesoctocog Alfa on Long-term Joint Health in Participants With Hemophilia A in Taiwan
This is a national, multicenter, retrospective/prospective, observational study in Taiwan designed to assess effectiveness, safety, and usage of efanesoctocog alfa prophylaxis treatment in hemophilia A participants.
- Trial name
- PROTECT-ALT (NCT06684314)
- Testing
- Efanesoctocog alfa
- Where
- 10 sites in Taiwan
- Volunteers
- 79 people
- Sponsor
- Sanofi
High Cholesterol/Hyperlipidemia, High Blood Pressure
OAT-GUT-BRAIN: Effects of Oats and Rice on Comprehensive Health of Metabolically Challenged Individuals
The overall objective of this research entity is to reveal the comprehensive health impact of oats in metabolically challenged individuals in a 6-week intervention, compared to that of rice.
- Conditions
- High Cholesterol/Hyperlipidemia, High Blood Pressure, Overweight and Obesity
- Trial name
- NCT05526092
- Testing
- Dietary intervention, Postprandial meal test
- Where
- 2 sites in Finland
- Volunteers
- 72 people
- Sponsor
- University of Turku
Atrial Fibrillation, Atrial Flutter
Triggers and Risk Factors for Recurrence of Atrial Arrhythmias With the Use of Long-term Monitoring
A prospective cohort study to evaluate the association between various triggers encountered in daily life and induction of atrial arrhythmias (atrial fibrillation, atrial flutter, atrial tachycardia and premature atrial…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Atrial Arrhythmia, Atrial Tachycardia
- Trial name
- TriggersAF (NCT05526170)
- Testing
- Devices for long-term monitoring of objective and subjective parameters of the body
- Where
- Lithuania
- Volunteers
- 182 people
- Sponsor
- Vilnius University