Clinical trials: Loop Ileostomy
Loop Ileostomy
Fortune of Temporary Ileostomies in Patients After Rectal Cancer Surgery
The risk factors for stoma reversal failure have been rarely studied, which is probably one of the worst scenarios for a case who has a sphincter preserving procedure for a rectal cancer and is expecting to have regular bowel…
- Trial name
- NCT02532478
- Volunteers
- 160 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Ileostomy, Rectal Neoplasms
Diverting Loop Ileostomy: With or Without Rod
Diverting ileostomies are created to protect a rectal anastomosis or in situations with a risk of intestinal perforation. Currently, the application of a rod to hinder slippage of the loop is an established technique to perform a…
- Trial name
- ROLLI (NCT00959738)
- Testing
- Diverting loop ileostomy with rod, diverting loop ileostomy without rod
- Where
- Switzerland
- Volunteers
- 121 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Loop Ileostomy Closure
Prophylaxis of Ileostomy Closure Site Hernia by Placing Mesh
Design Prospective , randomized, parallel phase IV. Objectives Main objective Evaluate the effectiveness of the placement of a resorbable mesh in the prevention of incisional hernia of the abdominal wall at the site of a loop…
- Trial name
- ILEOCLOSE (NCT02226887)
- Testing
- MESH, NO MESH, Post-operative Imaging
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Ileostomy - Stoma, Rectal Neoplasms
Peritoneum and Anterior Rectus Sheath Suturing and Ileostomy
In the era of laparoscopy, ileostomy via specimen extraction site has been proposed as a novel approach for temporary ostomy creation to prevent anastomotic leak after laparoscopic low anterior rectal resection.
- Trial name
- NCT06344923
- Testing
- Ileostomy with a support rod instead of the layer of peritoneum and anterior rectus sheath suturing, Ileostomy with the layer of the peritoneum and anterior rectus sheath suturing
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Qilu Hospital of Shandong University
Ileostomy, Colorectal Surgery
Early vs Standard Ileostomy Reversal
This randomized controlled trial compares early (8 weeks) versus standard (12 weeks) ileostomy reversal in patients with confirmed anastomotic healing, evaluating postoperative complications and recovery outcomes.
- Trial name
- NCT07601594
- Testing
- Ileostomy reversal
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Gulab Devi Hospital
Elective Colorectal Surgery
Impact of a Bridge Device on the Loop Ileostomy
During the creation of an ileostomy, a bridge device is systematically placed in an aim to reduce wound and peritoneal contamination by stools. Nevertheless no evidence was reported to justify this issue.
- Trial name
- IBIP (NCT02756273)
- Testing
- bridge device, no bridge device
- Where
- 3 sites in France
- Volunteers
- 166 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Bowel Dysfunction, Colon Disease
Enteral Feeding of Fibre to Improve Microbiota
Following surgical removal of diseased bowel, patients often require a temporary redirection of bowel contents to a stoma, to allow healing prior to re-joining of the remaining bowel at a later date.
- Conditions
- Bowel Dysfunction, Colon Disease, Ileum--Diseases
- Trial name
- NCT06288464
- Testing
- Soluble Fibre
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Lancashire Teaching Hospitals NHS Foundation Trust
Rectal Cancer
Early Closure of Temporary Loop Ileostomy After Rectal Resection for Cancer
Early Closure of Temporary Loop Ileostomy After Rectal Resection for cancer
- Trial name
- NCT01865071
- Testing
- loop ileostomi
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Odense University Hospital
Rectum Cancer
PRELOOP Trial: Synthetic Versus Biological Mesh for Prevention of Incisional Hernia After Loop-ileostomy Closure
This study compares a synthetic mesh and biological implant in prevention of incisional hernia after loop-ileostomy closure.
- Trial name
- NCT03445936
- Testing
- Parietene Macro, Permacol
- Where
- 4 sites in Finland
- Volunteers
- 100 people
- Sponsor
- University of Oulu
Postoperative Ileus
Does Bowel Stimulation Before Loop Ileostomy Closure Reduce Postoperative Ileus?
Postoperative ileus is the most commonly observed morbidity following ileostomy closure. Studies have previously demonstrated that the defunctionalized bowel of a loop ileostomy undergoes a series of functional and structural…
- Trial name
- NCT02559635
- Testing
- Bowel stimulation, Nestle Resource
- Where
- Canada
- Volunteers
- 101 people
- Sponsor
- Jewish General Hospital
Rectal Neoplasms, Low Anterior Resection
Use of One Kind of Controllable Tube Ileostomy in the Low Rectal Cancer
Most surgeons suggest the use of fecal diverting to address the high morbidity and mortality associated with anastomotic leakage (AL) in patients with high risk factors on AL who are undergoing low anterior resections(LAR).
- Trial name
- CTI (NCT02012023)
- Testing
- Low anterior resection, tube ileostomy, loop ileostomy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Clostridium Difficile Colitis
Optimal Surgical Treatment Of Fulminant Clostridium Difficile Colitis
The investigators hypothesize that minimally invasive ileal diversion with intraoperative colonic lavage using a high volume polyethylene glycol/electrolyte solution will clear Clostridium difficile infection resulting in…
- Trial name
- NCT01441271
- Testing
- Ileal diversion and lavage, total abdominal colectomy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Massachusetts General Hospital
Ulcerative Colitis, Ileostomy - Stoma
Is Diverting Loop Ileostomy Necessary in Completion Proctectomy With Ileal Pouch Anal- Anastomosis: A Multicentre, Randomized Study of the GETAID Chirurgie Group. IDEAL Trial
Defunctioning ileostomy has demonstrated its benefits (rate and seriousness of anastomotic leakage) in cancer for low colorectal and coloanal anastomoses, whereas there are no such good quality evidences in case of ileal…
- Trial name
- IDEAL (NCT03872271)
- Testing
- ileal pouch-anal anastomosis with diverting loop ileastomy
- Where
- France
- Volunteers
- 194 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Surgical Wound Infection
Trial to Reduce Wound Infection With Contralateral Drainage in Loop Ileostomy Closure
1. Introduction: The most common complication of loop ileostomies closure for rectal cancer patients undergoing a low anterior rectum resection, is the superficial surgical site infection (incidence 2-40%).
- Trial name
- NCT02574702
- Testing
- application of a contralateral drainage (Penrose ® device)
- Where
- Spain
- Volunteers
- 78 people
- Sponsor
- Corporacion Parc Tauli
Fulminant Clostridium Difficile Colitis
Loop Ileostomy With Colonic Lavage for Fulminant Clostridium Difficile Colitis
LAY SUMMARY Clostridium Difficile (C.difficile) is a bacterial infection that can cause an inflammation of the colon, (C.difficile colitis). This sometimes progresses to a sudden and severe illness.
- Trial name
- NCT02347280
- Testing
- Loop Ileostomy with colonic lavage, Total Abdominal Colectomy with end ileostomy
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Jewish General Hospital
Surgery, Fast Recovery Surgery
Evaluation of Short-term Outcomes of Ambulatory Loop Ileostomy Reversal
Based on enhanced recovery after surgery (ERAS), ambulatory loop ileostomy reversal (ALIR) has been reported in developed countries. However, there is still no research proposing how to carry out ALIR in developing countries.
- Trial name
- NCT05552170
- Testing
- day-case surgery
- Where
- China
- Volunteers
- 216 people
- Sponsor
- West China Hospital
Ileostomy Closure in Rectal Cancer
Day-Case Closure of Loop Ileostomy in Rectal Cancer
The aim of this study is to investigate if day-case closure of ileostomy is feasible and safe.
- Trial name
- NCT02774447
- Testing
- ileostoma closure
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Colorectal Surgery
Ghost Ileostomy (GI) Versus Loop Ileostomy (LI) After Colorectal Resections
A Ghost Ileostomy (GI) as an alternative to a diverting protective Loop Ileostomy (LI) after colorectal resection is offered the patients at risk preoperatively. A GI is only applied in cases, who would receive a LI otherwise.
- Trial name
- GI_versus_LI (NCT04573075)
- Testing
- Ghost ileostomy, loop ileostomy, no outlet
- Where
- Germany
- Volunteers
- 257 people
- Sponsor
- Evangelisches Klinikum Köln Weyertal gGmbH
Rectal Neoplasms, Ostomy
Trial Comparing Loop Ileostomy Versus Loop Transverse Colostomy
The purpose of this study is to determine which stoma creation technique is preferable after low anterior resection of the rectum.
- Conditions
- Rectal Neoplasms, Ostomy, Neoplasms
- Trial name
- LIVELOC (NCT05745909)
- Testing
- Laparoscopic or open low-anterior resection of the rectum with TME and created loop transverse colostomy, Laparoscopic or open low-anterior resection of the rectum with TME and created loop ileostomy
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- Republican Clinical Oncological Dispensary, Ministry of Health of the Republic of Bashkortostan
Incisional Hernia of Anterior Abdominal Wall
Phasix Mesh Underlay During Loop Ileostomy Closure
This prospective study will evaluate whether placement of long-acting absorbable Phasix mesh during loop ileostomy closure reduces the development of an incisional hernia at the ileostomy closure site in patients with a BMI…
- Trial name
- NCT07871630
- Testing
- Long-acting absorbable mesh
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Corewell Health West