Clinical trials: Loss of Consciousness
Syncope, Pre-Syncope
Evaluation of a Mobile Cardiac Outpatient Telemetry System Versus Standard Loop Event Monitor
Comparing the arrhythmia diagnostic yield of MCOT as compared to standard loop event monitors in patients presenting with palpitations, syncope or near syncope occurring less frequently than every 24 hours.
- Conditions
- Syncope, Pre-Syncope, Palpitations
- Trial name
- NCT00295204
- Where
- 13 sites in United States
- Volunteers
- 300 people
- Sponsor
- Cardionet
Healthy Volunteers
Unconscious Processing in Decision-making
This behavioral study on healthy participants aims to provide a baseline reference for assessing alterations of decision-making performance in pathological conditions.
- Trial name
- NCT05774847
- Testing
- No intervention
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Conscious Sedation
Feasability Test of a Handset Device to Detect Levels of Sedation and Loss of Consciousness
Sedation is often administered to relieve anxiety and discomfort during uncomfortable procedures in elderly patients. Patient control of sedation offers many potential benefits for patients and healthcare professionals, including…
- Trial name
- NCT01778608
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Groningen
Traumatic Brain Injury, Coma
Optimized Therapy in Severe Traumatic Brain Injured Patients
Severe traumatic brain injury is associated with life-threatening and incapacitating secondary injury. Contemporary therapeutic interventions are aimed at preventing and treating secondary damage.
- Trial name
- NCT02130674
- Testing
- Dipeptiven
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- University of Zurich
Brain Death, Liver Disease
Pre-recovery Bedside Liver Biopsy in Brain Death Organ Donors
This study's objective is to obtain preliminary data to test the hypotheses that percutaneous liver biopsy in brain death donors is safe and provides reliable histological information.
- Trial name
- PPB (NCT01810640)
- Testing
- Percutaneous Liver Biopsy
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Rutgers, The State University of New Jersey
Electroencephalogram, Consciousness, Loss of
The Electroencephalogram and Clinical Effect of Ketamine
The electroencephalography (EEG) is a noninvasive medical technique for monitoring and recording the electrical activity of brain.
- Trial name
- NCT03679390
- Testing
- Ketamine
- Where
- Taiwan
- Volunteers
- 17 people
- Sponsor
- National Taiwan University Hospital
Syncope, Pediatric
Pediatric Adhesion and New Dermal Approach Study
The purpose of this study is to see if the Zio® monitor device can be worn by children for up to 14-days and to determine if the skin preparation process will provide good adherence to the skin and clear signal quality.
- Conditions
- Syncope, Pediatric, Congenital Athymia, Congenital Heart Disease
- Trial name
- PANDA (NCT07118124)
- Testing
- Zio monitor
- Where
- 4 sites in United States
- Volunteers
- 36 people
- Sponsor
- iRhythm Technologies, Inc.
Syncope, Vasovagal
Treatment Strategy of Vasovagal Syncope
This is a prospective, international multi-center, open-labeled, randomized trial. The investigator speculated that CNA prevents more patients with moderate to severe VVS from syncope recurrence compared to midodrine.
- Trial name
- CAMPAIGN (NCT05803148)
- Testing
- Cardioneuroablation, Midodrine Oral Tablet
- Where
- China
- Volunteers
- 184 people
- Sponsor
- China National Center for Cardiovascular Diseases
Syncope
BAsel Syncope EvaLuation (BASEL IX) Study
Syncope is a major health problem. In the emergency department (ED), the management of patients with syncope still remains a clinical challenge because underlying diseases and prognosis can be extremely various.
- Trial name
- NCT01548352
- Where
- 15 sites in United States, Argentina and 7 more
- Volunteers
- 3,500 people
- Sponsor
- University Hospital, Basel, Switzerland
Aortic Stenosis, Heart Failure
High-Sensitivity Troponin T Plasma Levels in Patients With Aortic Stenosis (Tyrolean Aortic Stenosis Study-2)
TASS-2 (Tyrolean Aortic Stenosis Study-2) aims to characterize the clinical value of minimally elevated troponin T plasma levels both in patients with asymptomatic and symtomatic aortic stenosis.
- Conditions
- Aortic Stenosis, Heart Failure, Syncope, Angina Pectoris
- Trial name
- TASS-2 (NCT02448485)
- Testing
- Aortic Valve Intervention (surgical or transcatheter)
- Where
- Austria
- Volunteers
- 10,000 people
- Sponsor
- Medical University Innsbruck
Postural Tachycardia Syndrome, Syncope
Qualitative Sweat Distribution During Tilt Table Procedure
This study uses an Alizarin Red powder mixture to characterize the sweat distributions in youth during tilt table testing. Patients with a known orthostatic sweat response from a prior clinical tilt table test in the…
- Conditions
- Postural Tachycardia Syndrome, Syncope, Anxiety
- Trial name
- NCT02329548
- Testing
- Alizarin Red
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Nationwide Children's Hospital
Disorder of Consciousness, Minimally Conscious State
Temporal Interference Stimulation for Disorders of Consciousness
This study aims to investigate whether a new non-invasive brain stimulation technique, called temporal interference stimulation, can influence brain activity and potentially improve signs of consciousness in patients with severe…
- Conditions
- Disorder of Consciousness, Minimally Conscious State, Vegetative State, Unresponsive Wakefulness Syndrome
- Trial name
- NCT07874178
- Testing
- Temporal Interference
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Minimally Conscious State
Closed-loop tDCS in Patients in Minimally Conscious State
This research will test a closed-loop system using EEG-arousal measures (spectral entropy) to define the best moment of the day for application of transcranial direct current stimulation (tDCS) in patients in MCS This study aims…
- Trial name
- NCT03810079
- Testing
- Anodal transcranial direct current stimulation
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- University of Liege
Brain Injury Traumatic Mild, Brain Injuries
Screening Emotions in Adolescents at the Hospital for mTBI
The goal of this observational study is to develop and validate a clinical tool to predict which adolescents aged 11 to less than 18 years of age with mild traumatic brain injury (mTBI) are at an increased risk for developing…
- Conditions
- Brain Injury Traumatic Mild, Brain Injuries, Brain Injuries, Acute, Head Injury With Intracranial Hemorrhage
- Trial name
- SEARCH-mTBI (NCT06370520)
- Testing
- Validated Questionnaires, Questionnaires, Clinician / Medical Record Variables
- Where
- 6 sites in United States
- Volunteers
- 2,592 people
- Sponsor
- University of California, Davis
Brain Death, Organ Donation
Methods of Confirmation of Brain Death
The purpose of this study is to describe the use of methods confirming brain death in the real clinical practice of the transplant program in the Czech Republic.
- Trial name
- NCT04734574
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Brno University Hospital
Disorder of Consciousness
Clinical Validity of the Minimally Conscious State "Plus" and "Minus"
The goal of this observational retrospective study is to investigate and compare the clinical evolution of a sample of patients with the diagnosis of MCS+ versus MCS- according to the CRS-R.
- Trial name
- NCT05954650
- Testing
- Rehabilitation
- Where
- 2 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Hospitales Nisa
Atrial Fibrillation, Atrial Flutter
The Z Stitch Early Bed Rest Assessment Study
The goal of this study is to understand the effects of early mobilization after a Z stitch procedure in patients undergoing certain heart-related treatments.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Supraventricular Tachycardia, Syncope
- Trial name
- ZEBRA (NCT06087497)
- Testing
- Early mobilization
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Oregon Health and Science University
Syncope
Implantable Loop Recorder in Traumatic Syncope
Prospective, observational registry enrolling consecutive patients with recurrent, unexplained, traumatic syncope underwent implantable loop recorder implantation with the aim to evaluate the incidence of recurrence of traumatic…
- Trial name
- TRAUMA (NCT04832542)
- Testing
- outpatient follow-up
- Volunteers
- 488 people
- Sponsor
- Azienda Ospedaliera Cardinale G. Panico
Cerebral Hematoma, Traumatic, Intracerebral Hemorrhage, Traumatic
Interest of Real Time Measurement of Autonomous Nervous System for the Detection of Brain Death
Context: A major lack of organ donors is a serious public health problem. It determines a prolonged delay before a transplant can be performed and thus a significant number of deaths of patients waiting for transplantation.
- Conditions
- Cerebral Hematoma, Traumatic, Intracerebral Hemorrhage, Traumatic, Traumatic Brain Hemorrhage, Traumatic Brain Injury
- Trial name
- MEANS (NCT00918970)
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Postural Orthostatic Tachycardia Syndrome (POTS), Syncope
Abdominal and Lower Extremity Compression During Tilt Table Testing in Adolescent POTS Patients
Postural orthostatic tachycardia syndrome (POTS) is a common cause of orthostatic intolerance in adolescents and adults. Compression stockings are commonly recommended as a treatment modality for POTS, but the effects of…
- Trial name
- NCT01795469
- Testing
- Zoex compression garment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nationwide Children's Hospital