Clinical trials: Low; Birthweight
Neonatal Respiratory Failure
Non Invasive Ventilation Versus Continuous Positive Airway Pressure After Extubation of Very Low Birth Weight Infants.
The purpose of this study is to determine whether Nasal intermittent positive pressure ventilation (NIPPV) non synchronized is better than continuous positive airway pressure (NCPAP)in preventing extubation failure within 72 h…
- Trial name
- VNINS (NCT01778829)
- Testing
- CPAP ventilation mode, NIPPV ventilation mode
- Where
- Chile
- Volunteers
- 220 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Premature Birth
Theory of Mind in Preschool Children, School Children, Youths and Adults Born Preterm or Full-term
This study tests preschoolers, school children, youths and young adults, who were born preterm or full-term, in their theory of mind abilities.
- Trial name
- NCT02628015
- Where
- Germany
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of Bonn
Premature Infant, Respiratory Distress Syndrome in Premature Infant
30% or 60% Oxygen at Birth to Improve Neurodevelopmental Outcomes in Very Low Birthweight Infants
Preterm birth, or birth before 37 weeks' gestation, is increasingly common, occurring in 8 percent of pregnancies in Canada. Preterm birth is associated with many health complications, particularly when the birth happens before…
- Conditions
- Premature Infant, Respiratory Distress Syndrome in Premature Infant, Neurodevelopmental Outcome
- Trial name
- HiLo (NCT03825835)
- Testing
- 30% oxygen group, 60% oxygen group
- Where
- 14 sites in Canada, Ireland
- Volunteers
- 1,203 people
- Sponsor
- University of Alberta
Infant, Very Low Birth Weight
OptiMoM Kindergarten Study
In Canada, the leading cause of long-term disability in children is being born at very low birth weight (VLBW). To help improve outcomes, nutrition is a modifiable aspect of infant care.
- Trial name
- NCT02759809
- Testing
- Pasteurized donor human breastmilk, Preterm formula
- Where
- Canada
- Volunteers
- 158 people
- Sponsor
- The Hospital for Sick Children
Cerebral Palsy
The Changing Panorama in Risk Factors of Cerebral Palsy
The study will be carried of scanning the database of 296 individuals with cerebral palsy followed in the university pediatric rehabilitation clinic.
- Trial name
- NCT04716530
- Testing
- No intervention is associated with the study.
- Where
- Turkey (Türkiye)
- Volunteers
- 296 people
- Sponsor
- Istanbul Medeniyet University
Preterm Birth, Skin to Skin Contact
Promoting Kangaroo Care for Preterm or Low Birthweight Infants in Rural India
The goal of this study is to develop ways to help mothers of preterm or low birth weight infants do Kangaroo Care at home after discharge from the Neonatal Intensive Care Unit in rural India.
- Conditions
- Preterm Birth, Skin to Skin Contact, Low Birth Weight, Kangaroo Care
- Trial name
- NCT07231432
- Testing
- Behavioral Interventions
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- University of Massachusetts, Worcester
Weight Gain
Emollient Therapy In Preterm & Low Birth Weight Neonates: A Randomized Clinical Trial
The objective of this study is to assess the impact of emollient therapy on gain in weight and length among preterm and low birth weight babies.
- Trial name
- NCT04619758
- Testing
- Emollient (sunflower oil)
- Where
- Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Dr. Abdul Ahad Jamshaid
Intraventricular Haemorrhage, Pulmonary Haemorrhage
Prediction of Major Bleeding in ELBW-infants (<1000g) by Sequential Coagulation Monitoring
Up to now, only data about early and single coagulation screening exist in extreme low birth weight infants (ELBW) infants. In neonatal practice, coagulation abnormality in preterm babies is primarily investigated by measuring…
- Trial name
- NCT01976013
- Testing
- Coaguchek
- Where
- Austria
- Volunteers
- 126 people
- Sponsor
- Medical University of Vienna
Infant, Newborn, Infant, Low Birth Weight
Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure
This multicenter trial tested whether inhaled nitric oxide would reduce death or the need for oxygen in preterm infants (less than 34 weeks gestational age) with severe lung disease.
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- Preemie iNO (NCT00016523)
- Testing
- Inhaled nitric oxide
- Where
- 17 sites in United States
- Volunteers
- 420 people
- Sponsor
- NICHD Neonatal Research Network
Plasmodium Falciparum Malaria, Malaria Diagnosis
Additional Screening With Sensitives RDTs and Malaria
National malaria control strategies in pregnant women relies primarily on effective case management along with the use of long lasting insecticide-treated nets (LLINs)throughout pregnancy and intermittent preventive treatment…
- Trial name
- ASSERMalaria (NCT04147546)
- Testing
- Additional screening using ultra sensitive RDTs, Dihydroartemisinin-piperaquin, Reminders
- Where
- Burkina Faso
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche en Sciences de la Sante, Burkina Faso
Infant, Premature, Nutrition, Enteral
Aspiration of Residual Gastric Contents
The primary purpose of this study is to determine nutrition outcomes and risks to gastrointestinal integrity and function of aspirating for routine gastric contents prior to each feeding in very low birth weight premature infants.
- Trial name
- NCT01863043
- Testing
- No aspiration of gastric contents, Routine aspiration of gastric contents
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- University of Florida
Bronchopulmonary Dysplasia, Death
Systemic Management in Extremely Preterm and Extremely Low Birth Weight Infants
to estimate incidences of major complications, such as bronchopulmonary dysplasia, death, and delivery room resuscitation among extremely preterm and extremely low birth weight infants in Northern China
- Trial name
- NCT06082414
- Testing
- no interventions
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Peking University
Osteopenia of Prematurity
The Effect of Physical Activity on Bone Mineralization and Immune System in Very Low Birth Weight Infants
Studies have demonstrated that brief (5-10 min a day) passive range-of-motion exercise is beneficial for bone development in very low birth weight (VLBW) preterm infants.
- Trial name
- NCT01042639
- Testing
- passive physical activity
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- Meir Medical Center
Macrosomia, Low Birth Weight
Wales Electronic Cohort for Children
The investigators are developing a research platform capable of improving children's health through the generation of knowledge from analysis of routinely collected data from within and outside the health service.
- Conditions
- Macrosomia, Low Birth Weight, Premature Birth, Childhood Obesity
- Trial name
- WECC (NCT01136681)
- Where
- 2 sites in United Kingdom
- Volunteers
- 900,000 people, healthy volunteers welcome
- Sponsor
- Swansea University
Infant, Very Low Birth Weight
Quality Improvement Project - Evaluation of Current Standard of Care for Feeding Practices in the NICU
Human milk is associated with substantial benefits to infants' health and development, especially in premature infants. Some mothers are unable or unwilling to provide breast milk to their infant.
- Trial name
- NICU (NCT01204983)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Baylor College of Medicine
Diarrhea, Respiratory Infection
Impact of Zinc Supplementation in Low Birth Weight Infants on Severe Morbidity, Mortality and Zinc Status: A Randomized Controlled Trial
There are currently no interventions available to substantially reduce the incidence of low birth weight (LBW) apart from increasing the age at marriage, maternal iron supplementation and possibly improved energy intakes.
- Conditions
- Diarrhea, Respiratory Infection, Low Birth Weight
- Trial name
- NCT00272142
- Testing
- Zinc
- Where
- India
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Society for Applied Studies
Low Birth Weight
Synthesis of Glutathione From Low Birth Weight Newborn Babies
The aim of the study is to determine mechanisms leading to glutathione deficiency in low birth weight newborn babies. Compared to full term neonates, depletion in this population may be due to a decreased synthesis rate or to an…
- Trial name
- glutathione (NCT00607061)
- Testing
- Blood sample collection
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Nantes University Hospital
Bilirubin-induced Neurologic Dysfunction, Hyperbilirubinemia
Bilirubin Binding Capacity to Assess Bilirubin Load in Preterm Infants
Most preterm newborns are managed by phototherapy to reverse hyperbilirubinemia with the intent to prevent bilirubin neurotoxicity.
- Conditions
- Bilirubin-induced Neurologic Dysfunction, Hyperbilirubinemia, Kernicterus, Infant, Premature
- Trial name
- NCT02691156
- Testing
- Bilirubin Binding Capacity, End-tidal Carbon Monoxide, Carboxyhemoglobin
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Stanford University
Respiratory Distress Syndrome
Extubation Readiness Study in Very Low Birthweight Infants
The objective of this study is to determine whether use of the spontaneous breathing trial allows for earlier successful extubation of very low birth weight (VLBW) infants who are intubated for >48 hours and have not yet been…
- Trial name
- NCT01471431
- Testing
- spontaneous breathing trial
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- University of Pennsylvania
Very Low Birth Weight Baby, Premature Birth
Human-derived Human Milk Fortifiers (H2MF), Gut Microbiota and Oxidative Stress in Premature Infants
This is a randomized controlled trial of a human-derived human milk fortifier (H2MF) vs standard bovine-derived human milk fortifier (HMF) evaluating fecal microbiota and fecal and urinary biomarkers of oxidative stress in…
- Conditions
- Very Low Birth Weight Baby, Premature Birth, Microbial Colonization, Oxidative Stress
- Trial name
- NCT03214822
- Testing
- H2MF
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba