Clinical trials: Low Back
Low Back Pain and Core Muscle, Disc Herniation
Neural Control and Mechanosensation in Spine Muscle
Low back pain (LBP) is a condition that affects a majority of the US population and is responsible for a significant proportion of health care costs and utilization.
- Trial name
- NCT07003802
- Testing
- Resistance exercise
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Pregnancy, Breech Presentation
Effects of Relaxing Hydrotherapy in Third Trimester of Pregnancy
This study will be the first scientific approach to investigate physical and psychological effects of the passive hydrotherapy-method WATSU (WaterShiatsu) on women and their unborn children at the third trimester of pregnancy.
- Conditions
- Pregnancy, Breech Presentation, Low Back Pain, Stress, Psychological
- Trial name
- NCT01708018
- Testing
- WATSU
- Where
- Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Neck Pain, Low Back Pain
Study to Demonstrate That Muscle Pattern Recognition (MPR) is an Effective Evaluation Tool for Musculoskeletal Neck or Back Pain
The investigators hypothesize that non able-bodied participants with reported acute, sub-acute, or chronic symptoms of neck or back pain of a musculoskeletal origin will have magnetic resonance imaging (MRI), X-ray and blood…
- Trial name
- NCT00134225
- Testing
- Muscle Pattern Recognition (MPR)
- Where
- 4 sites in United States, Canada
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- iTech Medical, Inc.
Occupational Exposure, Musculoskeletal Pain
Can Work be Organized to Become More Health Promoting for Employees in Home Care Services?
This is a two-group, cluster randomized controlled trial designed to assess a health promoting intervention in the home care sector.
- Conditions
- Occupational Exposure, Musculoskeletal Pain, Work-related Injury, Low Back Pain
- Trial name
- GoldiCare (NCT05487027)
- Testing
- Goldilocks work principle
- Where
- 11 sites in Norway
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Low Back Pain
Serum Cytokine Levels in Patients with Lumbal Disc Herniation and Effectiveness of Exercise
The aim of the study is to investigate serum cytokine levels and the efficacy of lumbar stabilization exercises in patients with lumbar disc herniation with and without neurological deficits.
- Trial name
- NCT04912388
- Testing
- Lumbal stabilization excercises, Conventional exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Low Back Pain
Effects of Tactile Stimuli for Lumbar Multifidus Muscle Activation in Healthy Adults and Patients With Low Back Pain
The purpose of this study is to compare combined tactile stimulation and verbal instruction to verbal instruction only on lumbar multifidus muscle activation in asymptomatic healthy adults and in patients with LBP.
- Trial name
- NCT02836860
- Testing
- Tactile stimuli
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Non Specific Low Back Pain
AI-Enhanced Telerehabilitation Program Using Automated Video Analysis and Personalized Feedback on Pain, Disability, Mobility, Endurance, for Chronic Non-Specific Low Back Pain in College Students.
This study tests whether an artificial intelligence (AI)-enhanced telerehabilitation program can effectively treat chronic non-specific low back pain in college students.
- Trial name
- NCT07145996
- Testing
- AI Based Exercises, Standard Telerehabilitation
- Where
- India
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Majmaah University
Upper Back Pain, Lower Back Pain
Late Postpartum Period and Pain
Upper back, lower back and pelvic girdle pain significantly affect women's lives, especially in the postpartum period. This study aimed to characterize the frequency and severity of upper back, lower back and pelvic girdle pain…
- Conditions
- Upper Back Pain, Lower Back Pain, Pelvic Girdle Pain
- Trial name
- NCT06745752
- Where
- Turkey (Türkiye)
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Low Back Pain, Lumbago
Home Program Education for Patients With Low Back Pain
The primary purpose of this study is to assess the effect size of the change in Oswestry Disability Questionnaire (ODQ) score over the 8 week follow-up period between the video based instruction or standard of care hand-out with…
- Conditions
- Low Back Pain, Lumbago, Spinal Instability
- Trial name
- NCT02427438
- Testing
- Video, Handout
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Vitamin D
Association of Vitamin D Intake, and Associated Factors with Low Back Pain: a Retrospective Cohort Study
While there have been studies indicating a connection between insufficient levels of vitamin D and persistent low back pain (LBP), there is still a lack of definitive evidence.
- Trial name
- NCT06765382
- Where
- Jordan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mutah University
Chronic Low-back Pain (cLBP)
Pain Assessment Through Integrated Neurophysiology and Multidimensional Profiling
This observational case-control study aims to investigate the central neurophysiological mechanisms underlying non-specific chronic low back pain (CLBP) with neural mechanosensitivity, with wearable Optically Pumped Magnetometers…
- Trial name
- PAIN-MAP (NCT07846163)
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Chronic Low Back Pain
Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain
Noxious stimuli occurring intraoperatively and postoperatively generate central sensitization, decreasing pain thresholds and ultimately increasing analgesic requirements.
- Trial name
- NCT00899600
- Testing
- Ketamine, Normal saline
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Back Pain Lower Back Chronic
Caudal Epidural Injection of Dextrose For Low Back Pain
Objective: The purposes of the study are to 1. Explore the immediate and short term (to 48 hour) analgesic potential of epidural D5W in comparison to normal saline. 2.
- Trial name
- NCT01547364
- Testing
- Saline, Dextrose
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Smigel, Liza, M.D.
Low Back Pain
Study to Investigate the Potential Pharmacological Effect of Oral Palmitoylethanolamide (PEA) Therapy in the Management of Low Back Pain (Neuropathic Pain)
This clinical trial aims to evaluate the potential therapeutic effects of oral supplemental Palmitoylethanolamide (PEA) Phytosome® in managing neuropathic low back pain.
- Trial name
- NCT06694337
- Testing
- 300 mg Palmitoylethanolamide (PEA) Phytosome®, 450 mg Palmitoylethanolamide (PEA) Phytosome®, Control group
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Chronic Low Back Pain
A Comparative Study: Non-Surgical Spinal Decompression and Spinal Manipulative Therapy- Utilizing a Quantifiable Musculoskeletal Functional Assessment Risk Analysis Tool (MSDR®) in Patients With Chronic Low Back Pain
To administer the MSDR® (Musculoskeletal Disorder Reporting) instrument to document the musculoskeletal profile of patients with chronic low back pain, a prospective, non-randomized, multicenter treatment trial
- Trial name
- NCT00732394
- Testing
- MSDR
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- MedAppraise, Inc.
Back Pain
Comparison of Activator Manipulation Versus Manual Side Posture Manipulation in Patients With Low Back Pain
This study compared the treatment effect of Activator Methods Chiropractic Technique (AMCT) and manual Diversified type spinal manipulative therapy in a sample of patients with acute and sub-acute low back pain.
- Trial name
- NCT00497861
- Testing
- Activator Methods Chiropractic Technique
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cleveland Chiropractic College
Low Back Pain, Manuel Therapy
Effect of SNAGs on Stiffness of Lumbar Stabilizer Muscles
Low back pain is a common health problem worldwide. Epidemiological studies have shown that 70-80% of all people are affected at least once in their lifetime.
- Trial name
- NCT04475770
- Testing
- Real Sustained Natural Apophyseal Glides (SNAGS)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istinye University
Low Back Pain
Back Beliefs Among the General Population
In the current study we aim to evaluate the effects of a short educational video on improving the belief that "the back is fragile and needs to be protected" among the German speaking Swiss general population.
- Trial name
- NCT06104995
- Testing
- Interventional video, Control video
- Where
- Switzerland
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Chronic Low Back Pain, Postural Low Back Pain
Characterization by Clinimetric Indicators of Chronic Low Back Pain Subjects Versus Healed Patients
Pretending with the use of accelerometers and pressure platform, determine indicators that are useful to therapists to assess postural control and balance, to subsequently allow to evaluate the effect of therapeutic interventions…
- Trial name
- NCT03635242
- Testing
- Control. no therapeutic program, Experimental. Therapeutic program
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Interleukines
Study of Cytokines Serum Levels in Chronic Low Back Pain
The purpose of this study is to: evaluate if there is an association between elevated levels of cytokines and chronic pain due to herniated disk disease measured cytokines levels in chronic low back pain and in healthy subjects.
- Trial name
- cytokine (NCT00991042)
- Testing
- blood collect
- Where
- Brazil
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo