Clinical trials: Low Back Disorder
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Spinal Minimally Invasive and Interventional Surgeries
Application of 3D printing guide plate in spinal minimally invasive and interventional surgeries
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Radiculopathy, Lumbosacral Facet Joint Syndrome
- Trial name
- NCT05487690
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Low Back Pain
A Randomized, Equivalence Trial of Percutaneous Lumbar Adhesiolysis and Caudal Epidural Steroid Injections
The purpose of this study is to: evaluate the effectiveness of percutaneous epidural adhesiolysis in managing chronic low back and/or lower extremity pain in patients without post lumbar surgery syndrome or spinal stenosis and…
- Trial name
- NCT01053273
- Testing
- Caudal Epidural Injection, percutaneous adhesiolysis
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah
Pain, Low Back Pain
Low Level Laser Therapy in the Dorsal Root Ganglion in the Treatment of Chronic Low Back Pain
Chronic axial low back pain is a public health problem and has a high socioeconomic impact. The dorsal ganglion of the second spinal nerve (GDL2) is a cluster of neuronal bodies responsible for sensory afferent inputs from more…
- Conditions
- Pain, Low Back Pain, Nociceptive Pain, Neuropathic Pain
- Trial name
- NCT02529670
- Testing
- Laser, Drug: Lidocaine, Radiofrequency
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- University of Nove de Julho
Non-specific Low Back Pain, Low Back Pain
Correlation Between Hip Mobility and Thoracic Flexion in Patients With Non-Specific Low Back Pain
This cross-sectional observational study investigates the relationship between hip joint mobility and thoracic flexion in patients diagnosed with non-specific low back pain.
- Conditions
- Non-specific Low Back Pain, Low Back Pain, Musculoskeletal Disorders, Thoracic Spine Dysfunction
- Trial name
- NCT07429279
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Deraya University
Chronic Pain, Opiate Dependence
Developing Brain Stimulation as a Treatment for Chronic Pain in Opiate Dependent
Effective control of chronic pain is a top priority in the United States, as approximately 10% of adults have severe chronic pain - most of which is chronic lower back pain (CLBP).
- Conditions
- Chronic Pain, Opiate Dependence, Lower Back Pain
- Trial name
- NCT03681769
- Testing
- iTBS to the left dlPFC, cTBS to the mPFC
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Medical University of South Carolina
Lumbar Spondylosis, Low Back Pain
Catgut Embedding for Lumbar Spondylosis With Blood Stasis Syndrome
The goal of this clinical trial is to learn if catgut embedding works to treat chronic low back pain in adults with lumbar spondylosis and "Blood Stasis" syndrome.
- Trial name
- NCT07590050
- Testing
- Catgut embedding using PDO thread, Electro-acupuncture, Lifestyle and Exercise Counseling
- Where
- Vietnam
- Volunteers
- 66 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Back Pain Lower Back Chronic
Effectiveness of a Psychoeducative Intervention on Patients With Cronic Low Back Pain
One of the treatment modalities currently available in this hospital to treat this type of patients with low back pain who present with chronic pain are the group sessions that are carried out to provide information to the…
- Trial name
- PNE (NCT03964389)
- Testing
- Pain Neuroscience Education" (PNE)
- Where
- Spain
- Volunteers
- 179 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Low Back Pain, Hip Osteoarthritis
Observational Study of the Development of Low Back Pain After Total Hip Arthroplasty.
The investigators are going to observe the appearance of low back pain in patients who have undergone hip prosthesis surgery.
- Conditions
- Low Back Pain, Hip Osteoarthritis, Arthropathy of Hip
- Trial name
- NCT05647629
- Testing
- Total hip arthroplasty
- Where
- 2 sites in Spain
- Volunteers
- 618 people
- Sponsor
- Universidad de Zaragoza
Back Pain, Acute Pain
Tolperisone in Acute Muscle Spasm of the Back
This is a double-blind, randomized, placebo-controlled, parallel group study of the efficacy and safety of tolperisone (a non-opioid) or placebo administered as multiple doses three times a day (TID) in approximately 400 male and…
- Conditions
- Back Pain, Acute Pain, Back Spasm Upper Back, Back Strain
- Trial name
- STAR (NCT03802565)
- Testing
- Tolperisone
- Where
- 43 sites in United States
- Volunteers
- 415 people
- Sponsor
- Neurana Pharmaceuticals, Inc.
Musculoskeletal Diseases, Low Back Pain
Front Line Agreement in Diagnosis and Treatment for Musculoskeletal Dysfunctions
Background: This randomized study, conducted from October to December 2023 in the emergency department of Bethesda Hospital Basel, Switzerland, investigated a new model of care for patients presenting with non-urgent…
- Conditions
- Musculoskeletal Diseases, Low Back Pain, Emergency Service, Hospital, Physical Therapy Modalities
- Trial name
- DirectPhysio (NCT07443098)
- Testing
- Intervention: ED - physiotherapist group, Control: resident physician group
- Where
- Switzerland
- Volunteers
- 102 people
- Sponsor
- Bern University of Applied Sciences
Low Back Pain
Spine Rehabilitation Using Spine Flexion / Extension Full Active Range of Motion for Patients With Chronic Low Back Pain
The main objective of this study is to assess efficacy of a spine rehabilitation program, using spine flexion and extension full active range of motion, on physical disability of patients with chronic low back pain.
- Trial name
- REACTIVE (NCT05213845)
- Testing
- Spine flexion/extension active range of motion exercises
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Physical Therapy, Low Back Pain
GRAVITY System Therapy on Chronic Low Back Pain
The aim of the study was to examine the effect of GRAVITY system therapy on chronic disc-related pain in lumbar spine. Investigators made a hypothesis that patients who regularly perform core strengthening exercises based on…
- Conditions
- Physical Therapy, Low Back Pain, Chronic Pain
- Trial name
- GRAVITY (NCT04765293)
- Testing
- Physical Therapy
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Józef Piłsudski University of Physical Education
Chronic Low-back Pain, Lumbar Facet Joint Syndrome
Comparison of the Effectiveness of Ultrasound-guided Versus Radioguided Medial Lumbar Bundle Branch Block
In adults with chronic low back pain, the investigators will compare the effectiveness of the medial bundle branch block on three lumbar levels (L3-L4, L4-L5 and L5-S1) performed either by radiographic guidance or by ultrasound…
- Trial name
- NCT04658953
- Testing
- Ultrasound guided infiltration, Fluoroscopy guided infiltration
- Where
- 3 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Mixed Anxiety Depression, Diabetes Mellitus, Type 2
Concentrated Cross-disciplinary Group Intervention for Common Health Complaints (Including Post COVID-19 Fatigue)
The health care is faced by a growing challenge in the years to come: increasing age and chronic morbidity raising the costs, combined with decreased work participation.
- Conditions
- Mixed Anxiety Depression, Diabetes Mellitus, Type 2, Low Back Pain, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05234281
- Testing
- Interdisciplincary concentrated group rehabilitation
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- Helse i Hardanger
Low Back Pain (LBP), Low Back Disorder
Investigation of the Effect of Spine Health Training and Lumbar Region Support on Back Pain and Discomfort in City Bus Drivers: a Randomized Controlled Trial
The World Health Organization (WHO) classifies driving as a function of daily activities and social participation. Professional bus drivers have an important place in society for transportation.
- Trial name
- NCT06841107
- Testing
- Training was provided on spinal health., Training on spinal health was provided and lumbar region support was applied for 3 months.
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Pamukkale University
Fibromyalgia, Low Back Pain
Effects of Instrument Assisted Soft Tissue Mobilization and Bowen Technique in Fibromyalgia
To compare the effects of Bowen's and Graston Technique in patients of chronic low back pain for reducing pain, enhancing lumbar range of motion and physical functioning and reducing depression.
- Trial name
- NCT05969912
- Testing
- Graston Technique (Instrumented assisted soft tissue mobilization), Bowen's Technique(Soft tissue technique)
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Chronic Low Back Pain
Chronic Low Back Pain Patients' Expectations Toward Physiotherapy
Non-specific chronic low back pain guidelines recommend rehabilitation along with a biopsychosocial approach. However, though psychological and social issues address important needs of professionals and patients, they have been…
- Trial name
- CLBPEXPECT (NCT02123680)
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Haute Ecole de Santé Vaud
Radiculopathy, Low Back Pain, Mechanical
Efficacy of Ultrasound Versus Short Wave Diathermy in the Treatment of a Slipped Disc of the Lower Back
Chronic low back pain is a common problem which results in reduced functionality, quality of life and general well being. Conservative treatment includes patient education, exercise, maintaining a healthy body mass index and…
- Conditions
- Radiculopathy, Low Back Pain, Mechanical, Herniated Disk Lumbar
- Trial name
- NCT03835182
- Testing
- Ultrasound group, Short wave diathermy group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Baskent University
Intervertebral Disc Degeneration, Chronic Low-back Pain
Efficacy of Intradiscal Injection of Autologous BM-MSC in Worker Patients Affected by Chronic LBP Due to Multilevel IDD
ACTIVE is a phase II B efficacy monocenter, prospective, randomized, controlled double blinded trial, in which intra-discal autologous adult BM-MSC therapy will be compared with sham treated controls.
- Trial name
- ACTIVE (NCT04759105)
- Testing
- Autologous BM-MSC
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Pain, Chronic, Musculoskeletal Pain
Complementary Management of Chronic Neck and/or Low Back Pain With a Pain Relief Kit
The purpose of this project is to determine the effect of a multimodal non-pharmacological Pain Relief Kit on the pain, functioning, patient satisfaction, and opioid consumption of individuals suffering from an acute pain episode…
- Conditions
- Pain, Chronic, Musculoskeletal Pain, Low Back Pain, Neck Pain
- Trial name
- NCT03157544
- Testing
- multimodal non-pharmacological Pain Relief Kit
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- Sport and Spine Rehab Clinical Research Foundation