Clinical trials: Low Back Dysfunction
Chronic Non-Specific Low Back Pain, Cognitive Decline
The Impacts of Chronic Non-specific Low Back Pain on Cognitive Functions of Older Adults
Chronic non-specific low back pain (CNSLBP) is a prevalent condition among older adult and has been associated with an increased risk of executive function impairment.
- Conditions
- Chronic Non-Specific Low Back Pain, Cognitive Decline, Cross-Sectional Study, Older Adults
- Trial name
- NCT06704425
- Testing
- For observational studies, participants are not assigned an intervention as part of the study.
- Where
- 3 sites in Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Female Sexual Dysfunction (FSD)
Impact of Tibial Nerve Stimulation on Lumbopelvic Mechanics and Sexual Function in Females With Sexual Dysfunctions
This study will be conducted to examine the effects of Transcutaneous Tibial Nerve Stimulation (TTNS) on lumbopelvic mechanics and sexual function in females with sexual dysfunctions and low back pain
- Trial name
- NCT07764445
- Testing
- Pelvic floor exercise, transcutaneous tibial nerve stimulation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Chronic Low-back Pain, Sacroiliac Joint Dysfunction
The Effects of Sacroiliac Joint Dysfunction on Gait and Disability
It has been reported that gait coordination changes in patients with chronic low back pain, walking slower, taking shorter steps and having asymmetrical stride lengths compared to their healthy peers.
- Conditions
- Chronic Low-back Pain, Sacroiliac Joint Dysfunction, Gait, Unsteady, Disability Physical
- Trial name
- NCT05786118
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Kutahya Health Sciences University
Low Back Pain
Prevention of Chronic Low Back Pain in Female Nurses
NURSE-RCT is a randomized controlled trial which aims at prevention of evolution of chronic low back pain (LBP) and related disability in female nurses.
- Trial name
- NURSE-RCT (NCT01465698)
- Testing
- Exercise, Counseling, Exercise and counseling
- Where
- Finland
- Volunteers
- 219 people
- Sponsor
- UKK Institute
Chronic Low Back Pain, Type 2 Diabetes Mellitus
OMT of Somatic Dysfunction and Chronic Low Back Pain in Patients With Type 2 Diabetes Mellitus
The study hypothesis is based on osteopathic medical philosophy that: 1) the body is a unit; 2) the body has inherent self-regulatory mechanisms; 3) structure and function are interrelated; and 4) rational treatment is based on…
- Trial name
- NCT02054650
- Testing
- Osteopathic Manual Treatment (OMT)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of North Texas Health Science Center
Sexual Dysfunction, Low Back Pain
The Effect of Physical Therapy on Sexual Function
Sexual function in low back pain and after lumbar surgery has been evaluated in many studies In a few studies, sexual function problems after surgery have also been reported.
- Trial name
- NCT06017830
- Testing
- Physical treatment agents
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Chronic Pain, Low Back Pain
Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain
The purpose of this study is to investigate, in two phases: (1) the feasibility and safety of Virtual Embodiment Therapy in treating chronic pain of lower back and upper limbs and (2) the efficacy of Virtual Embodiment Therapy on…
- Conditions
- Chronic Pain, Low Back Pain, Fibromyalgia, Upper Extremity Dysfunction
- Trial name
- NCT04060875
- Testing
- Karuna Labs Virtual Reality Software
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Karuna Labs Inc.
Temporomandibular Joint Disorder, Low Back Pain
Myofascial Release Therapy for TMD Pain: A Randomized Trial
We aim to compare the effectiveness of MFR and exercise therapy on mobility and function by investigating the effectiveness of the Myofascial Release Technique (MFR), which we will apply to the muscles we choose related to the…
- Conditions
- Temporomandibular Joint Disorder, Low Back Pain, Myofascial Release
- Trial name
- NCT05673642
- Testing
- Myofascial Release Techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Chronic Low Back Pain (CLBP), Heart Rate Variability
Autonomic Differences in Heart Rate Variability Between Healthy and Chronic Low Back Pain Subjects
This study aims to evaluate the autonomic differences in heart rate variability (HRV) between healthy individuals and those with chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Heart Rate Variability, Autonomic Nervous System Dysfunction
- Trial name
- NCT06760390
- Where
- Spain
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Low Back Pain
Influence of a Educational Internet-based Intervention in Chronic Low Back Pain Patients: A Mixed Methods Approach
Aim: The aim of this project is to identify chronic low back pain patients´ beliefs about the origin and meaning of pain for developing a biopsychosocial web-based educational intervention.
- Trial name
- NCT02369120
- Testing
- Educational intervention, Normal care by GP
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Universitat de Lleida
Sacroiliac Joint Dysfunction
Radiofrequency Nerve Ablation Versus Sham to Treat Chronic Low Back Pain Caused by Sacroiliac Joint Dysfunction
Trial will enroll qualified subjects at a 2:1 ration to receive radiofrequency ablation or sham. At six weeks follow up they will be unblinded; sham subjects will then be given option to receive treatment.
- Trial name
- NCT01104051
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Coastal Orthopedics & Sports Medicine
Chronic Low Back Pain (CLBP), Sacroiliac Joint Dysfunction
Connective Tissue Dry Needling for Low Back Pain Related to Local Posterior Superior Iliac Spine Pain
This single-blind randomized controlled trial will aim to determine the effectiveness of a connective tissue dry needling (CTDN) technique, in reducing pain and improving function in individuals with chronic mechanical low back…
- Conditions
- Chronic Low Back Pain (CLBP), Sacroiliac Joint Dysfunction, Mechanical Low Back Pain
- Trial name
- NCT07345871
- Testing
- Connective tissue dry needling, Exercise therapy
- Volunteers
- 42 people
- Sponsor
- University of Social Welfare and Rehabilitation Science
Cognitive Dysfunction, Low Back Pain
Frequency of Cognitive Dysfunction in Patients With Chronic Low Back Pain
This study evaluates cognitive dysfunction status and related factors in patients with chronic low back pain over the age of 60.
- Trial name
- NCT06278467
- Testing
- visual pain scale (VASpain/fatigue), Beck depression index (BDI),, Pain catastrophizing scale, sleep quality with a single Likert type question in the Pittsburgh questionnaire, Roland Morris Disability Questionnaire, quality of life with Short Form-36 ( SF-36),
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Konya Beyhekim Training and Research Hospital
Osteoarthritis, Rheumatoid Nodule
Cellular & Biocellular Regenerative Therapy in Musculoskeletal Pain, Dysfunction,Degenerative or Inflammatory Disease
Musculoskeletal disorders and degeneration represent injuries or pain in the body's joint ligaments, tendons, muscles, nerves, and skeletal elements that support extremities, spine and related tissues.
- Conditions
- Osteoarthritis, Rheumatoid Nodule, Degenerative Joint Disease, Tendinopathy
- Trial name
- BRT (NCT03090672)
- Testing
- Normal Saline, Tissue Stromal Vascular Fraction, Platelet Rich Plasma
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Robert W Alexander, MD
Non-specific Low Back Pain, Low Back Pain
Correlation Between Hip Mobility and Thoracic Flexion in Patients With Non-Specific Low Back Pain
This cross-sectional observational study investigates the relationship between hip joint mobility and thoracic flexion in patients diagnosed with non-specific low back pain.
- Conditions
- Non-specific Low Back Pain, Low Back Pain, Musculoskeletal Disorders, Thoracic Spine Dysfunction
- Trial name
- NCT07429279
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Deraya University
Low Back Pain, Recurrent
Treatment of Veterans With Chronic Low Back Pain
The purpose of this study is to assess the effectiveness of hypnosis in the treatment of chronic low back pain.
- Trial name
- CLBP (NCT00361270)
- Testing
- Hyp-8, Hyp-2 w recordings, Hyp-8 w recordings
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- VA Office of Research and Development
Lower Back Pain
Post Isometric Relaxation and Core Stability Exercises in Sacroiliac Joint Dysfunction
There is growing evidence on the effects of post isometric relaxation exercises and core stability exercises on pain and disability secondary to various disorders.
- Trial name
- NCT05529602
- Testing
- conventional physical therapy, relaxation exercise
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Low Back Pain, Functional Motor Disorder
Ultrasound-guided Percutaneous Electrical Stimulation for Gluteus Muscle Dysfunction After Low Back Pain Episode
Percutaneous ultrasound-guided neuromodulation (US-guided PNM) is the electrical stimulation of a peripheral nerve at some point along its pathway or at a muscular motor point under the guidance of an ultrasound probe with a…
- Trial name
- NCT06873386
- Testing
- Valera & Minaya protocol, High-frequency US-guided PNM
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Marc Badia
Pelvic Floor Dysfunction, Low Back Pain
Sacral Stimulation in Women With Low Back Pain: Effects on Pelvic Functions and Daily Life
Pelvic floor dysfunction is a term used to describe a variety of disorders involving moderate to severe impairment of the pelvic floor muscles.
- Trial name
- NCT07094698
- Testing
- sacral stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uskudar University
Multi-Organ Disorder
Pulsed RF Neuromodulation and Leukocyte-Rich PRP for Refractory Low Back Pain
This clinical trial aims to check the safety and efficacy profile of pulsed radiofrequency (RF) neuromodulation combined with leukocyte-rich platelet-rich plasma (PRP) injections for the treatment of refractory low back pain due…
- Trial name
- Multifidus (NCT06524531)
- Testing
- Pulsed RF Neuromodulation, Leukocyte-Rich PRP Injection, Physiotherapy Alone
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Iffat Anwar Medical Complex