Clinical trials: Low Back Pain, Chronic
Non Specific Chronic Low Back Pain, Exercise Therapy
Effect of Video-based Stabilization Exercises on Pain, Function, Adherence, Kinesiophobia & QoL in NSCBP Patients
This randomized controlled study aims to evaluate the effectiveness of a 6-week home-based stabilization exercise program in individuals with non-specific chronic low back pain.
- Trial name
- NCT07005765
- Testing
- Video-Based Stabilization Exercise Program, Brochure-Based Stabilization Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Serra Sürel
Chronic Pain, Chronic Low-back Pain
Ultra Low Frequency Spinal Cord Stimulation for Chronic Low Back Pain
The Presidio Medical Ultra Low Frequency (ULF™) Spinal Cord Stimulation (SCS) System is intended to provide pain relief to participants who have been clinically diagnosed with chronic low back pain with or without leg pain.
- Trial name
- NCT05837234
- Testing
- ULF SCS
- Where
- 3 sites in Australia
- Volunteers
- 55 people
- Sponsor
- Presidio Medical, Inc
Chronic Low Back Pain (Non-specific, Uncomplicated)
Evaluation of the Effectiveness and Safety of Mesotherapy in the Treatment of Chronic Low Back Pain Syndrome
The aim of this study is to evaluate the effectiveness of collagen mesotherapy in the treatment of chronic low back pain (CLBP) in the lumbosacral spine.
- Trial name
- NCT07675304
- Testing
- Tropocollagen type I, Lignocaine 1% concentration solution
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Chronic Low Back Pain, Self-Management
Physical Activity on Neurophysiologic Gene Expression Profiles of Chronic Low Back Pain
This pilot project will provide an understanding of the contextual variables responsible for chronic low back pain. These variables include, genetic variation, pain sensitivity, reactivity, pain catastrophizing, perceived stress…
- Trial name
- PROPEL (NCT03637998)
- Testing
- Problem-solving Pain to Enhance Living Well (PROPEL)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Connecticut
Fibromyalgia (FM), Chronic Low Back Pain (CLBP)
Pain Neuroscience Education for Chronic Pain
Chronic pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, with a high prevalence in Spain (25.9%) and an average duration of 6.83 years, highlighting its significant health…
- Conditions
- Fibromyalgia (FM), Chronic Low Back Pain (CLBP), Chronic Pain
- Trial name
- PNE (NCT07693998)
- Testing
- Therapeutic Exercise and Education in Pain Neuroscience
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- University of Valencia
Chronic Pain, Low Back Pain
High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System
Study designed to compare the conventional stimulation programming versus the high frequency stimulation programming of the spinal cord stimulator for subjects who already have a spinal cord stimulator.
- Conditions
- Chronic Pain, Low Back Pain, Radiculopathy, Complex Regional Pain Syndrome (CRPS)
- Trial name
- HFSCS (NCT02265848)
- Testing
- High frequency stimulation, Low frequency stimulation
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The Center for Clinical Research, Winston-Salem, NC
Chronic Low-back Pain
The Effectiveness of Kinesio Taping in Patients With Chronic Low Back Pain
The objective of this study is to determine the effectiveness of Kinesio taping (KT) with Conventional Physical therapy (CPT) - Transcutaneous Electrical Nerve Stimulation (TENS) and Supervised Exercise therapy and CPT in the…
- Trial name
- NCT05173948
- Testing
- Kinesio taping, Conventional physical therapy
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- University of Tabuk
Gluteus Medius, Ultrasonography, NSCLBP
Gluteus Medius Strengthening n Non Specific Chronic Low Back Pain
To study the effect of adding selected G Med muscle strengthening exercises to the APTA-guided program on pain, disability level, and G Med macromorphology in patients with NSCLBP.
- Trial name
- NCT05521165
- Testing
- therapeutic exercises
- Volunteers
- 58 people
- Sponsor
- Cairo University
Low Back Pain
Potential of Virtual Reality in Primary Chronic Low Back Pain
This is a single-case experimental design study enrolling individuals with chronic low back pain who will be receiving pain science education and virtual reality over 3 weeks.
- Trial name
- NCT07742111
- Testing
- Pain science education and virtual reality
- Where
- Portugal
- Volunteers
- 12 people
- Sponsor
- Aveiro University
Chronic Low-back Pain (cLBP)
Virtual Reality Based High-intensity Interval Training in Chronic Low Back Pain
One of the most prevalent causes of pain on a global scale is chronic musculoskeletal pain. Low back pain is a prevalent manifestation of chronic musculoskeletal pain.
- Trial name
- NCT07388134
- Testing
- Virtual reality based high intensity interval training (VR-HIIT) group, High intensity interval training (HIIT) group
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Universidad de Granada
Chronic Low Back Pain, Opioid-induced Hyperalgesia
Opiate-Induced Tolerance & Hyperalgesia in Pain Patients
Opiates such as morphine are the cornerstone medications for the treatment of moderate to severe pain. Recent evidence suggests that pain patients on chronic opioid therapy become more sensitive to pain (hyperalgesia) over time.
- Trial name
- NCT00246532
- Testing
- Morphine
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Major Depressive Disorder, Back Pain
Duloxetine Treatment of Major Depression and Chronic Low Back Pain For Older Adults
The following primary hypotheses will be tested: 1. During Step 1: Major Depressive Disorder (MDD) or Chronic Low Back Pain (CLBP) in < 40% of the initial 60 subjects treated with duloxetine (DUL) + Clinical Management(CM) during…
- Conditions
- Major Depressive Disorder, Back Pain, Aged
- Trial name
- ACHIEVE2 (NCT00696293)
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Peptic Ulcer
Efficacy and Safety Study of HZT-501 in Reducing the Risk of Ibuprofen-associated Ulcers
The purpose of this study is to evaluate whether HZT-501 is effective in reducing the rate of development of ibuprofen-associated ulcers in patients who require long-term daily use of ibuprofen.
- Trial name
- NCT00450658
- Testing
- HZT-501, Ibuprofen
- Volunteers
- 627 people
- Sponsor
- Amgen
CRPS (Complex Regional Pain Syndromes), Radiculopathy
Intermittent Dosing of Dorsal Root Ganglion Stimulation as an Alternate Paradigm to Continuous Low-Frequency Therapy
This study seeks to evaluate the use of intermittent dosing as an alternative paradigm for patients with DRG stimulation in place for at least 1 year and minimum 50% pain relief in the targeted area.
- Conditions
- CRPS (Complex Regional Pain Syndromes), Radiculopathy, Peripheral Neuropathy
- Trial name
- NCT04909138
- Testing
- DRG stimulation 20 Hz 30/90, DRG stimulation 5 Hz 30/90
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Rush University Medical Center
Chronic Low Back Pain
Chronic Low Back Pain Graded - Exposure Psychoeducation Intervention
This study will examine the effectiveness of one of two psychoeducation treatments on chronic low back pain.
- Trial name
- VRGE (NCT03909048)
- Testing
- Interactive - Psychoeducation, Non-interactive Psychoeducation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Chronic Low Back Pain
Bright Light Treatment At Home To Manage Chronic Pain In U.S. Veterans
Nearly 50% of U.S. veterans report they experience pain on a regular basis. This chronic pain often co-occurs with other disorders including post-traumatic stress disorder (PTSD), depression, anxiety and insomnia.
- Trial name
- NCT02373189
- Testing
- Bright light
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Rush University Medical Center
Chronic Low Back Pain, Neck Pain
The Healing Context in Complementary and Alternative Medicine (CAM): Initial Validation Study
The overall objective of this study is to develop and test an efficient set of self-report instruments to measure Complementary and Alternative Medicine(CAM)-relevant contextual factors important in healing.
- Trial name
- HEAL (NCT02161887)
- Where
- 3 sites in United States
- Volunteers
- 207 people
- Sponsor
- University of Pittsburgh
Chronic Low-back Pain
Effects of Pain Neuroscience Education With Conventional Physical Therapy in Patients With Chronic Low Back Pain
Low back pain is currently considered to be the most common cause of disability.When low back pain occurs sensitivity of body increases which decreases overall body activity.Physical inactivity negatively effects recovery from…
- Trial name
- NCT05680506
- Testing
- Pain neuroscience education, Standard Therapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Foundation University Islamabad
Chronic Low Back Pain
Effect of Passive Versus Active Aquatic Therapy Compared With Conventional Physiotherapy for Chronic Low Back Pain
This study is designed to help people with chronic low back pain, which is pain in the lower back that persists for more than three months and can affect daily life, including sitting, standing, walking, lifting, and other…
- Trial name
- AQUA-LBP (NCT07196826)
- Testing
- Active Aquatic Therapy, Passive Aquatic Therapy, Conventional Physiotherapy
- Where
- United Arab Emirates
- Volunteers
- 12 people
- Sponsor
- Gulf Medical University
Chronic Low-back Pain
Virtual Reality Based Physical Therapy for Patients With Lower Back Pain
The goal of this clinical trial is to compare chronic low back patients. The main question[s] it aims to answer are: pain and disability fear avoidance belief Participants will perform virtual reality exercises virtual reality…
- Trial name
- NCT05859321
- Testing
- Virtual reality Exercises, Routine Physiotherapy
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- University of Lahore