Clinical trials: Low Back Pain (LBP)
Low Back Pain
Orphenadrine and Methocarbamol for LBP
Low back pain is a common cause of visit to emergency department. It is not clear if skeletal muscle relaxants are of benefit for patients with acute low back pain.
- Trial name
- NCT02665286
- Testing
- Orphenadrine, Methocarbamol, Naproxen
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Montefiore Medical Center
Low Back Pain
Management of LBP With Radiculopathy.
This study is to determine the effectiveness of Neural mobilization(NM) technique compared with lumbar stabilization exercise (LSE) and Radial Extracorporeal Shock Wave Therapy (rESWT) in the physical therapy management of…
- Trial name
- NCT04022798
- Testing
- Exercise, manual therapy
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Tabuk
Chronic Low Back Pain (CLBP)
Clinical Investigation to Assess the Clinical Effect of the LumbaCure® Intervention on Patients Suffering From Chronic Low Back Pain
Low Back Pain (LBP) is one of the common causes of morbidity worldwide, with a one-month prevalence of 23.3 %. Number of people with LBP reached 577 million people in 2020.
- Trial name
- LumbaCure2302 (NCT06662032)
- Testing
- LumbaCure®, Rehab program
- Where
- 2 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Odix
Pain, Musculoskeletal Manipulations
Effects of a Protocol of Hip Flexor Stretching on Chronic Mechanical, Non-specific LBP.
The goal of this clinical trial is to compare the effectiveness of a stretching, exercise and education protocol versus usual care in improving pain, function and disability in patients with non-specific mechanical chronic low…
- Conditions
- Pain, Musculoskeletal Manipulations, Low Back Pain, Mechanical
- Trial name
- HipFlexinCLBP (NCT06975345)
- Testing
- Multicomponent intervention. Hip flexors stretching, Strengthening exercises and education and medical treatment (Medication and medical counselling), Medical treatment.
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Low Back Pain (LBP)
Telerehabilitation in Managing Chronic Low Back Pain
The purpose of this study is to determine whether telerehabilitation is as effective as in-person rehabilitation in treating patients with chronic back pain in actual clinical practice settings.T he study will recruit eighty-four…
- Trial name
- NCT06844825
- Testing
- Tele rehabilitation, usual care only
- Volunteers
- 84 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Low Back Pain
The Efficacy of Zoledronic Acid in Modic Changes-related Low Back Pain (LBP)
Modic changes are associated with low back pain (LBP) both in clinical and general population-based samples. Type I changes are regarded as more likely to be painful than type II changes.
- Trial name
- NCT01330238
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- University of Oulu
Non-specific Low Back Pain
Effects of ELDOA on Hamstring Tightness
The purpose of this study is to find the effects of ELDOA in increasing hamstring length in patients with nonspecific low back pain.This research will bring awareness about the concept of ELDOA exercises among clinicians and…
- Trial name
- NCT04757441
- Testing
- Group A: Conventional Treatment + Elongation Longitudinaux Decoaption of Osteo-Articulaire, Group B: Conventional treatment
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Low Back Pain
Efficacy of the Combination of Ibuprofen and Paracetamol in Acute Non-specific Low Back Pain
The aim of the present study is to assess the efficacy and safety of paracetamol/ibuprofen Fixed Dose Combination (FDC) compared to ibuprofen in patients with uncomplicated non-specific acute low back pain after a 3-day treatment…
- Trial name
- NCT05222724
- Testing
- Tachifene, Brufen
- Where
- 11 sites in Italy, Poland
- Volunteers
- 176 people
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Discogenic Low Back Pain
PRP Versus NP Injections for Chronic Discogenic Low Back Pain
The purpose of this randomized, single-blind comparative-effectiveness pilot study is to compare the effectiveness of two types of injections on pain and function over 6 months in patients with chronic discogenic (originating…
- Trial name
- NCT07895225
- Testing
- Platelet-Rich Plasma (PRP) Injection, Nucleus Pulposus (NP) Injection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Walter Reed National Military Medical Center
Low-back Pain
Markers of Outcome - a Cohort Study of LBP in Primary Health Care
Low-back pain (LBP) is a complex and heterogeneous disorder commonly seen in primary health care. Despite a variety of treatment options available, it seems that few of these prevent recurrent LBP and chronicity.
- Trial name
- MOS (NCT03108339)
- Testing
- Guideline recommended physiotherapy care
- Where
- Sweden
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Low Back Pain, Lumbar Radiculopathy
Predictive Factors for LBP Interventional Treatment Outcomes
In this study, we are attempting to determine which factors are associated with interventional treatment outcome for LBP (and to what extent).
- Trial name
- NCT02329951
- Testing
- Facet intervention, Sacroiliac joint injection, Epidural steroid injection
- Where
- United States
- Volunteers
- 346 people
- Sponsor
- Johns Hopkins University
Mechanical Low Back Pain
Influence of Patient-Informed Choice in a Novel Treatment Model for LBP
1. (Primary) To compare the effectiveness of a patient guided choice of care using a patient decision support tool to clinical guided care within a novel care process for non-specific low back pain.
- Trial name
- NCT01744015
- Testing
- Patient Decision Making tool, Standard of care
- Where
- United States
- Sponsor
- Walsh University
Low Back Pain, Paraspinal Muscles
Transcutaneous Electrical Nerve Stimulation (TENS) for the Treatment of Low Back Pain (LBP) in Adults
The goal of this clinical trial is to assess the effects and safety of transcutaneous electrical nerve stimulation (TENS) in adults with myofascial low back pain.
- Conditions
- Low Back Pain, Paraspinal Muscles, CLBP - Chronic Low Back Pain
- Trial name
- NCT07368920
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xijing Hospital
Low Back Pain
Different Dosage Regimens of Methocarbamol/Paracetamol in Acute Non-specific Low Back Pain. MioPain Study
The aim of the study is to evaluate the efficacy and safety of different dosage regimens of the combination methocarbamol/paracetamol in the treatment of patients with acute non-specific Low Back Pain.
- Trial name
- MioPain (NCT05204667)
- Testing
- 380 mg/300 mg comprimidos metocarbamol/paracetamol - 4 times daily, 380 mg/300 mg comprimidos metocarbamol/paracetamol - 6 times daily
- Where
- 3 sites in Italy
- Volunteers
- 172 people
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Lumbar Disc Herniation With Radiculopathy, Low Back Pain (LBP)
"Effectiveness of Physical Therapy Added to Transforaminal Injection in Lumbar Radicular Pain"
The purpose of this study is to investigate whether adding conventional physical therapy modalities to transforaminal epidural steroid injection (TFESE) provides additional benefits in patients with acute radicular pain due to…
- Trial name
- NCT07467421
- Testing
- TFESE, TFESE+ CONVENTIONAL PHYSIOTHERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Training and Research Hospital
Chronic Pain
PNE Delivered With a VR Headset in Outpatient LBP Patients
The primary objective of this study is to explore the feasibility and acceptability of the delivery of educational content using a virtual reality headset in the setting of an outpatient physical therapy (PT) course of care for…
- Trial name
- NCT04777877
- Testing
- Pain Neuroscience Education delivered via a Virtual Reality Headset
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Spaulding Rehabilitation Hospital
Low Back Pain
Photobiomodulation Therapy (PBMT) in Patients With Low Back Pain (LBP)
Low back pain (LBP) is a highly prevalent condition worldwide and the leading cause of years lived with disability. In most cases, the specific pathological cause remains unidentified; therefore, the term non-specific low back…
- Trial name
- NCT04476095
- Testing
- Active PBMT
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- University of Nove de Julho
Low Back Pain
Implementation of P3C-LBP in Swedish Primary Care
The goal of this observational study is to evaluate the implementation of a patient centered coordination care (P3C) pathway for the management of patients with low back pain (LBP) in primary care, in Östergötland health care…
- Trial name
- P3C-LBP (NCT06240533)
- Where
- Sweden
- Volunteers
- 300,000 people
- Sponsor
- Linkoeping University
Low Back Pain
Thera-Band® HEP for LBP Secondary Prevention
The purpose of this study is to determine the effectiveness of a Thera-Band based home exercise program (HEP) on LBP and disability 4 weeks post treatment discharge.
- Trial name
- TBKT_HEP (NCT02355275)
- Testing
- Home Exercise Program
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Sport and Spine Rehab Clinical Research Foundation
Low Back Pain, Chronic Low-back Pain
Transcranial Direct Current Stimulation (tDCS) Combined With Aerobic Exercise in Chronic Nonspecific Low Back Pain (LBP)
The goal of this clinical trial is to learn about the effects of transcranial direct current stimulation (tDCS) combined with aerobic exercise in non-specific low back pain patients.
- Trial name
- tDCS (NCT05830851)
- Testing
- real tDCS and aerobic exercise
- Where
- 2 sites in Spain
- Volunteers
- 38 people
- Sponsor
- European University of Madrid