Clinical trials: Low Birth Weight
Bronchopulmonary Dysplasia, Apnea of Prematurity
Early Versus Late Caffeine for ELBW Newborns
Caffeine is routinely used in the management of apnea of prematurity. Extremely low birth weight (ELBW) infants are at higher risk of mortality and various neonatal morbidities such as bronchopulmonary dysplasia (BPD) for which…
- Trial name
- NCT02524249
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Wayne State University
Infant, Very Low Birth Weight
Oropharyngeal Administration of Colostrum to Very Low Birth Weight Infants
The purpose of this study is to explore the effects of Oropharyngeal administration of colostrum to very low birth weight infants on sIgA and lactoferrin, in order to explore the protect immune function of colostrum to very low…
- Trial name
- NCT02389478
- Testing
- Oropharyngeal administration of colostrums, Oropharyngeal administration of Normal saline
- Volunteers
- 64 people
- Sponsor
- Children's Hospital of Fudan University
Overweight, Pregnancy
A Low Glycemic Load Diet During Pregnancy in Overweight Women
This study will compare the effects of a low glycemic load versus standard diet for pregnancy on outcomes related to risk for obesity, diabetes, and heart disease in both mother and infant.
- Trial name
- NCT00364403
- Testing
- Low glycemic load, Low fat diet
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Boston Children's Hospital
Neonatal Respiratory Distress, Very Low Birth Weight Infant
PRICO: OPTI Target Range
The aim of the study is to determine if a narrower SpO2 Target Range setting automated control of FiO2 (A-FiO2) is more effective than a wider SpO2 Target Range
- Trial name
- POSTR (NCT06207994)
- Testing
- Narrow TR, Shifted TR
- Where
- Czechia
- Volunteers
- 11 people
- Sponsor
- Czech Technical University in Prague
Low Birth Weight
Probiotics-Supplemented Feeding in Extremely Low Birth Weight Infants
The overall purpose of this research is to test whether adding a supplement to the feeding of extremely low birth weight infant (infants weighing less than 2 pound 2 oz at birth) will help him/her achieve full feeding faster and…
- Trial name
- PAS (NCT01164124)
- Testing
- Probiotic supplementation (Lactobacillus rhamnosus GG and Bifidobacterium infantis)
- Where
- 3 sites in United States
- Volunteers
- 101 people
- Sponsor
- Vermont Oxford Network
Low Birth Weight Infants, Preterm Infants
Predictors and Outcomes of Kangaroo Mother Care: A Quasi-Experimental Study in Pakistan
This quasi-experimental study evaluated the impact of Kangaroo Mother Care (KMC) versus Conventional Care (CC) on the growth, developmental milestones, breastfeeding, vaccination, and mortality of low birth weight infants in…
- Trial name
- NCT06559020
- Testing
- Kangroo mother care
- Where
- Pakistan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Very Low Birth Weight Infant
Comparison of Early Versus Late Trophic Feeding
Local data on the neonatal outcomes in early versus late trophic feeding in preterm very low birth weight neonates in terms of mean hospital stay is scarce.
- Trial name
- NCT07229885
- Testing
- Early trophic feeding, Late trophic feeding
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- RESnTEC, Institute of Research
Intervention
Effect of Developmental Care on Very Low Birth Weight Infants
The goal of this clinical trial is to learn if developmental care works when implemented in very low birth weight infants. The main questions it aims to answer are: Does developmental care shorten the length of hospital stay in…
- Trial name
- NCT06515574
- Testing
- developmental care
- Where
- 2 sites in China
- Volunteers
- 1,600 people
- Sponsor
- Children's Hospital of Fudan University
ROP, Jaundice, Neonatal
Hyperbilirubinemia and Retinopathy of Prematurity in Preterm Infants: a Retrospective Study.
The goal of this retrospective observational study is to [learn about the correlation between hyperbilirubinemia and retinopathy of prematurity in preterm infants.
- Conditions
- ROP, Jaundice, Neonatal, Premature, Very Low Birth Weight Infant
- Trial name
- biliROP (NCT05806684)
- Testing
- ROP
- Where
- Italy
- Volunteers
- 1,586 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Pregnancy, Premature Birth
A Trial of Micronutrients and Adverse Pregnancy Outcomes
The purpose of this study is to examine the efficacy of multivitamin supplementation on fetal loss, low birth weight and severe preterm birth in healthy (HIV negative) women.
- Conditions
- Pregnancy, Premature Birth, Infant, Low Birth Weight, Pregnancy Outcomes
- Trial name
- NCT00197548
- Testing
- Multivitamins-vitamins B-complex, C, and E
- Volunteers
- 8,468 people
- Sponsor
- Harvard School of Public Health (HSPH)
Infant, Very Low Birth Weight, Infant, Premature, Diseases
Regulation of Cerebral Blood Flow in Very Low Birth Weight Infants
Advances in newborn intensive care have lead to dramatic improvements in survival for the most premature infants-often weighing 1 pound at birth.
- Conditions
- Infant, Very Low Birth Weight, Infant, Premature, Diseases, Cerebral Hemorrhage
- Trial name
- NCT00579943
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Arkansas
Breast-milk
Breast-milk Enema Administration to Stimulate Passage of Meconium
Lack of passage of meconium in preterm infants delays feeding advancement and may represent a risk factor for necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP).
- Trial name
- BEAM (NCT07661992)
- Testing
- breast milk
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wake Forest University Health Sciences
Hypoxia Neonatal, Premature
Pulse Oximetry Measurement and Transfusions
The primary purpose of this observational study was to determine if pRBC transfusions decrease the frequency of intermittent hypoxia events in very low birth weight infants (VLBW) during the first six weeks of life.
- Conditions
- Hypoxia Neonatal, Premature, Blood Transfusion
- Trial name
- POMAT (NCT04249193)
- Testing
- Transfusion
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- Christiana Care Health Services
Preterm, Low Birthweight
Low-Cost and Reusable Thermal Jacket for Managing Preterm or Low Birth Weight Neonates.
Globally, over 15 million neonates are born preterm each year. They account for approximately 30% of global neonatal deaths and 19% of total neonatal deaths in Bangladesh.
- Conditions
- Preterm, Low Birthweight, Hypothermia Neonatal
- Trial name
- NCT06277843
- Testing
- Thermal Jacket
- Where
- Bangladesh
- Volunteers
- 10 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Infant, Premature, Nutrition, Enteral
Aspiration of Residual Gastric Contents
The primary purpose of this study is to determine nutrition outcomes and risks to gastrointestinal integrity and function of aspirating for routine gastric contents prior to each feeding in very low birth weight premature infants.
- Trial name
- NCT01863043
- Testing
- No aspiration of gastric contents, Routine aspiration of gastric contents
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- University of Florida
Pregnancy, Weight Gain
Grocery Delivery and Healthy Weight Gain Among Low-income Pregnant Young Women
This project will increase knowledge about how a simple intervention, grocery delivery, impacts weight gain and diet among low-income pregnant young women. Results can then be used to support other pregnant young women.
- Trial name
- NCT05000645
- Testing
- Grocery delivery, Unsweetened beverage delivery
- Where
- United States
- Volunteers
- 570 people
- Sponsor
- University of Michigan
Low Birth Weight Baby, Small for Gestational Age (SGA)
Biological Impacts of Rising Temperatures on Maternal, Fetal, and Newborn Health: A Cohort Study (BIRTH Cohort)
The goal of this study is to learn how being exposed to high environmental temperatures during pregnancy affects the health of pregnant women and their babies.
- Conditions
- Low Birth Weight Baby, Small for Gestational Age (SGA), Preterm Birth, Pregnancy Complications
- Trial name
- BIRTH (NCT06957769)
- Testing
- heat stress
- Where
- 3 sites in Pakistan
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Gastric Residual Volume, Preterm Infant
Routine Versus no Assessment of Gastric Residual Volumes in Preterm Infants
The practice of checking gastric residuals is not evidence based. The amount of gastric residual volume (GRV) does not correlate with either feeding intolerance or development of NEC.
- Conditions
- Gastric Residual Volume, Preterm Infant, Feeding Disorder Neonatal
- Trial name
- NCT04062851
- Testing
- No Gastric residual volume monitoring
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- AdventHealth
Pulmonary Hypertension, Infant, Premature
Novel Echocardiographic Methods for Early Identification of Neonates at Risk for Chronic Pulmonary Hypertension
Chronic pulmonary hypertension (cPHT) is a serious cardiopulmonary disorder that causes low oxygen levels in the blood, difficulty in breathing and ultimately heart failure.
- Trial name
- NCT04402645
- Where
- 6 sites in United States, Canada and 2 more
- Volunteers
- 350 people
- Sponsor
- Mount Sinai Hospital, Canada
Vitamin D Deficiency
Effect of Vitamin D Supplementation on Health of Low Birth Weight Infants
The purpose of this study is to determine whether a weekly supplement of vitamin D to low birth weight term infants will reduce their mortality and hospital admissions and improve their immunity.
- Trial name
- DIVIDS (NCT00415402)
- Testing
- Vitamin D3
- Where
- India
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Delhi University