Clinical trials: Low Bone Density
Sickle Cell Disease, Sickle Cell Anemia
Sickle Cell Disease (SCD) Bone Pain Study
A prospective study to determine how low bone mineral density and/or vertebral compression fractures associate with pain in adults with sickle cell disease
- Conditions
- Sickle Cell Disease, Sickle Cell Anemia, Low Bone Density, Osteoporosis
- Trial name
- NCT05283148
- Testing
- Dual-energy X-ray absorptiometry, Vertebral fracture analysis, Adult Sickle Cell Quality of Life Measurement System pain impact questionnaire
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of California, Davis
Low Bone Mineral Density, Muscle Oxygenation
Bone and Muscle Oxygenation in Military Test Pilots
This prospective, single-group interventional pilot study will evaluate the effects of a 12-week resistance and core stabilization exercise program on bone mineral density and resting muscle oxygenation in male military test…
- Trial name
- BMO-MTP (NCT07787143)
- Testing
- Supervised Resistance and Core Stabilization Exercise Program
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Emine Merve Ersever
Iron Deficiency, Iron Deficiency Anemia (IDA)
Collegiate Athlete Study
The purpose of this study is to determine what percentage of Black collegiate athletes have low energy availability. It will also determine the percentage of Black collegiate athletes who have iron deficiency, suboptimal or low…
- Conditions
- Iron Deficiency, Iron Deficiency Anemia (IDA), Vitamin D Deficiency, Vitamin D Insufficiency
- Trial name
- NCT07631312
- Testing
- Iron and Vitamin D Deficiencies Correction
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Down Syndrome (DS), Low Bone Mineral Density
The Impact of Core Stability Versus Respiratory Muscle Strengthening Exercises on Bone Mineral Density in Children With Down Syndrome
Children with Down syndrome often exhibit diminished physical fitness levels and lower bone mass. Numerous factors contribute to this decrease in bone mass density, including decreased levels of leptin, reduced muscle mass and…
- Trial name
- NCT07328165
- Testing
- Core Stability Exercise Group, Respiratory Muscle Strengthening Group, Control /Conventional Physiotherapy Group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Asthma, Bone Density, Low
CT-Based Changes in Bone and Marrow Among Patients on Oral Steroids
The goal of this study is to assess the feasibility of emerging CT-based tools to measure changes in central and peripheral bone density, micro-structure, and marrow adipose tissue (MAT) among patients treated with oral steroids.
- Conditions
- Asthma, Bone Density, Low, Oral Steroid-Dependent Asthma (Disorder)
- Trial name
- NCT04518722
- Testing
- CT Scan, DXA Scan, Steroid Intake Questionnaire
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Iowa
Low Bone Density
Comparing Between Osseodensification Burs Versus Osteotome in Low Bone Density Areas.
The objective of this study is to compare the primary stability of implant sites prepared using conventional drilling, osseodensification (Densah bur), and osteotome preparation techniques, and to evaluate the influence of these…
- Trial name
- NCT07378020
- Testing
- Conventional Osteotomy, Densah Bur drilling, osteotome bone condensation
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Future University in Egypt
Osteoporosis, Postmenopausal, Bone Density, Low
The Effect of the Probiotic Strains on Bone Mineral Density in Postmenopausal Women
Osteoporosis is a systemic condition characterized by low bone mass and altered bone tissue microarchitecture, with the resulting greater bone fragility leading to fractures.
- Trial name
- NCT06375668
- Testing
- Probiotic
- Where
- 3 sites in Poland
- Volunteers
- 170 people
- Sponsor
- Nordic Biotic Sp. z o.o.
Trochanteric Fracture of Femur, Osteoporotic Fracture of Femur
FARE Augmentation of Proximal Femoral Fractures With CaS/HA and Systemic ZA
The goal of this clinical trial is to investigate the new bone formation around a metal device in the femoral head in patients with osteoporotic hip fractures undergoing surgical treatment with nails.
- Conditions
- Trochanteric Fracture of Femur, Osteoporotic Fracture of Femur, Hip Fractures, Bone Density, Low
- Trial name
- NCT06135298
- Testing
- OSTEOSYNTHESIS, Zoledronic acid, CERAMENT BONE VOID FILLER (BVF)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Aksaray University
Bone Density, Low, Bone Loss
Effects of Romosozumab on Bone Density in Women With Anorexia Nervosa
This protocol is a randomized, double-blind, placebo-controlled clinical trial which aims to investigate the effect of romosozumab on BMD in women with anorexia nervosa.
- Conditions
- Bone Density, Low, Bone Loss, Anorexia Nervosa, Eating Disorders
- Trial name
- NCT04779216
- Testing
- Romosozumab Prefilled Syringe, Zoledronic acid 5 mg
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Karen Klahr Miller, MD
Low Bone Density
Clinical Deployment and Validation of Rho
Osteoporosis is a widespread disease characterized by the loss of bone mineral density (BMD). 16 Bit has developed software, called RhoTM, that analyzes various x-rays, performed in patient age 50 and above for any clinical…
- Trial name
- NCT05245851
- Testing
- Opportunistic screening for low BMD
- Where
- 2 sites in Canada
- Volunteers
- 1,146 people
- Sponsor
- 16 Bit Inc.
Vitamin D Deficiency, Cystic Fibrosis
Efficacy of Intensive Cholecalciferol Monitoring and Supplementation on Serum vitD Levels in Pediatric Patients With CF
Cystic fibrosis (CF) is an autosomal recessive disease caused by alterations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, characterized by multisystemic alterations, mainly in the lung, intestine…
- Conditions
- Vitamin D Deficiency, Cystic Fibrosis, Bone Density, Low, Inflammation Chronic
- Trial name
- NCT05276960
- Testing
- Cholecalciferol Pill
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Low Bone Density, Osteoporosis
Effects of DHEA and Exercise on Bone Marrow Fat in Postmenopausal Women
Bone strength -the main determinant of bone fracture- is a function not only of bone mineral density (BMD) and microstructure, but also of its microenvironment, including bone marrow fat (BMF).
- Trial name
- NCT05316272
- Testing
- Exercise, DHEA
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Colorado, Denver
Low Bone Density
Evaluation of Implant Stability in Low Quality Bone Following the Use of Osseodensifiers Versus Ridge Expanders
the use of osseodensification technique compared to ridge expansion screws in low bone quality
- Trial name
- NCT05330546
- Testing
- Densah burs, Ridge expansion screws
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteopenia, Low Bone Density
Evaluation of the Effect of Spry Belt Treatment on Bone Turnover Marker Profile
To conduct a sham-controlled study to rigorously evaluate the effect of Spry Belt treatment on key bone turnover markers (BTMs) over a 12-week period.
- Trial name
- NCT05457036
- Testing
- Spry Belt
- Where
- 2 sites in United States
- Volunteers
- 94 people
- Sponsor
- Bone Health Technologies, Inc.
Low Bone Mineral Density, Postmenopausal Osteoporosis
Eldecalcitol and Calcitriol in Postmenopausal Women With Low Bone Mineral Density or Mild Osteoporosis
To investigate the efficacy and safety of eldecalcitol in postmenopausal women with low bone mineral density (BMD) or mild osteoporosis through a randomized, open-label, parallel controlled trial with calcitriol as the control.
- Trial name
- EFFECT (NCT05902078)
- Testing
- Eldecalcitol capsules, Calcitriol capsules
- Where
- 21 sites in China
- Volunteers
- 300 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Bone Density, Low, Bone Mineral Density in Children With Graves' Disease
Bone Mineral Density in Children With Graves' Disease
to evaluate bone mineral density in children with graves' disease
- Trial name
- NCT06375096
- Testing
- evaluate bone mineral density
- Volunteers
- 100 people
- Sponsor
- Assiut University
Osteoporosis, Osteopenia
Effects of OsteoStrong vs. Individually Adapted and Combined Training on Bone Health
The aim of this clinical trial is to investigate the effect of the OsteoStrong training method and the Individually Adapted and Combined Training on the bone health of older women with high fracture risk.
- Conditions
- Osteoporosis, Osteopenia, Bone Density, Low, Bone Loss
- Trial name
- NCT05721014
- Testing
- OsteoStrong, Individually Adapted and Combined Physical Training
- Where
- Sweden
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Bone Density, Low
Comparing the Hydrodynamic Piezoelectric Technique With Osseodensification for the Assessment of Internal Sinus Iift-ing
Successful osseointegration considered the cornerstone in implant stability which predict the highest implants success outcomes.
- Trial name
- RCT (NCT06285903)
- Testing
- internal sinus lift surgery
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Cerebral Palsy, Bone Density, Low
Relation Between Bone Mineral Density, Gross Motor Function and Quality of Life In Children With Cerebral Palsy
studying the relationship between Bone Mineral Density, Gross Motor Function and, Quality of Life with CP can provide valuable insights into the musculoskeletal consequences of motor impairments and guide interventions to improve…
- Conditions
- Cerebral Palsy, Bone Density, Low, Gross Motor Development Delay
- Trial name
- NCT06180395
- Testing
- Group 1, Group 2
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Mental Wellbeing, Depression, Anxiety
Effects of Vitamin D on the Behaviours, Mental, and Physical Health of Prisoners
This study aims to understand how vitamin D (VD) affects human health. Typically, prisoners are low on vitamin D, as it is difficult to receive through diet, and is mostly obtained via exposure to the sun.
- Conditions
- Mental Wellbeing, Depression, Anxiety, Bone Density, Low, Vitamin D Deficiency
- Trial name
- NCT05724316
- Testing
- Vitamin D supplement
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University