Clinical trials: Low Cardiac Output
Cardiac Output, Low, Cardiac Output, High
Continous Cardiac Output - Non-Invasive Evaluation (CONNIE)
The capnodynamic method non-invasively calculates effective pulmonary blood flow (EPBF) continuously during surgery. In this study EPBF is compared to cardiac output (CO) measured with Transpulmonary Thermodilution (TPTD) att…
- Trial name
- CONNIE (NCT03444545)
- Testing
- Capnodynamic method, Transpulmonary thermodilution
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Karolinska Institutet
Low Cardiac Output
Hemodynamic Survey Cardiac Surgical Scenarios
The purpose of this study is to find out the Lidco Rapid ( monitoring tool gives cardiac output) is as equivalent in determining the hemodynamic assessment in cardiac surgical scenarios as the most often used pulmonary artery…
- Trial name
- NCT02529033
- Testing
- LIDCO Rapid, Pulmonary artery catheter
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Shock, Cardiac Output, Low
Comparison of Allows Measurement of Cardiac Output Between Clearsight System and Transpulmonary Thermodilution
Correlation study between the data provided by two measurement systems, trans- pulmonary thermodilution and ClearSight © (non invasive), to determine the interest in routine use (cardiac output, cardiac index, stroke volume and…
- Trial name
- CONDUCT (NCT02728791)
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Brest
Congenital Heart Disease, Perioperative/Postoperative Complications
Central Venous to Arterial CO2 Difference and Low Cardiac Output Syndrome Related Outcomes in Children After Cardiac Surgery
The goal of this clinical trial is to compare the capability of 3 different bedside surrogates in children who underwent cardiac surgery and were admitted in intensive care unit.
- Conditions
- Congenital Heart Disease, Perioperative/Postoperative Complications, Lactate Blood Increase
- Trial name
- VACO2 (NCT06292910)
- Testing
- arterial and central venous blood gas analysis, lactate
- Where
- Thailand
- Volunteers
- 136 people
- Sponsor
- Prince of Songkla University
Surgery, Cardiac Output, Low
Reliability of a New Pulse Contour Technique for Diagnosing an Increase in Stroke Volume During a Fluid Challenge for Hemodynamic Optimization in Patients Scheduled for High-risk Abdominal Surgery: Comparison With Transthoracic Echocardiography: COMPARE Study
The present study aims at assessing the ability of a new pulse contour device for diagnosing a >15% stroke volume (SV) increase during patient hemodynamic optimization by fluid challenge in high risk abdominal surgery.
- Trial name
- COMPARE (NCT04871620)
- Testing
- >15% SV increase during fluid challenge
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Respiratory Failure Chronic, Obesity Hypoventilation Syndrome
Myocardial Effects of NIV in OHS Patients
Chronic effects of noninvasive ventilation on myocardial function in patients with obesity hypoventilation syndrome (OHS) are scarcely understood.
- Conditions
- Respiratory Failure Chronic, Obesity Hypoventilation Syndrome, Obstructive Sleep Apnea, Cardiac Output, Low
- Trial name
- NCT06486129
- Testing
- Noninvasive ventilation volume targetted
- Where
- Slovakia
- Volunteers
- 13 people
- Sponsor
- Pavol Jozef Safarik University
Cardiac Output, Low
Evaluation of the Impact of Ejection Fraction on Clinical Outcomes in Patients Undergoing Cardiovascular Surgery
This study evaluates the impact of ejection fraction (EF) on clinical outcomes in patients undergoing cardiovascular surgeries, specifically coronary artery bypass grafting (CABG) and heart valve replacement.
- Trial name
- NCT06468657
- Testing
- mortality rates
- Where
- Turkey (Türkiye)
- Volunteers
- 610 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Cardiac Output, High, Cardiac Output, Low
Pulse Contour Analysis and Tissue Oxymetry in Changing Vascular Tone
The purpose of this study is to compare changes of minimally invasive arterial pulse contour cardiac output with changes of intermittent and continuous thermodilution cardiac output by pulmonary artery catheter in hemodynamic…
- Conditions
- Cardiac Output, High, Cardiac Output, Low, Vasodilation, Vasoconstriction
- Trial name
- NCT00583687
- Testing
- Vigileo TM / Flotrac TM (Minimally invasive cardiac output system consisting of arterial line sensor and cardiac output monitor), Passive leg raising, Volume challenge / Change of vasoactive drugs or inotropics
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Acute Heart Failure, Low Cardiac Output Syndrome
Exogenous Ketones for Acutely Decompensated HEart Failure
This study will evaluate whether supplementation of exogenous ketones in patients with severe left ventricular dysfunction and acutely decompensated heart failure requiring inotropic therapy would improve the patient's…
- Conditions
- Acute Heart Failure, Low Cardiac Output Syndrome, Hemodynamic Instability, Ketosis
- Trial name
- KADHEF (NCT04698005)
- Testing
- 25g Ketone monoester without added salts
- Where
- Czechia
- Volunteers
- 24 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Cardiac Output, Low
Cardiac Output Autonomic Stimulation Therapy for Heart Failure (COAST-HF) - Human NeuroCatheter Study
A single-center feasibility study in patients undergoing cardiac catheterization, to investigate the acute hemodynamic effects of transvenous cardiac autonomic nerve stimulation.
- Trial name
- COAST-HF HNrCS (NCT02880683)
- Testing
- NeuroTronik CANS Therapy System
- Where
- Paraguay
- Volunteers
- 16 people
- Sponsor
- NeuroTronik Inc.
Cardiac Output, Low
Comparison Studies Comparing Hemodynamic Parameters Provided by the Caretaker Against Respective Gold Standard References
Comparison studies comparing hemodynamic parameters provided by the Caretaker against respective Gold Standard references.
- Trial name
- NCT05035719
- Testing
- non-invasive cardiac output monitor
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CareTaker Medical LLC
Very Low Birth Weight Infant, Very Preterm Maturity of Infant
USCOM Parameters in Preterm Infants: Reference Ranges
The goal of this observational study is to learn about the feasibility of hemodynamic measurement by the UltraSonic Cardiac Output Monitor (USCOM) in very preterm or very-low-birth-weight infants.
- Trial name
- NCT05961657
- Testing
- Hemodynamic measurements by USCOM
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione IRCCS San Gerardo dei Tintori
Low Cardiac Output
Comparison of Cardiac Output With LiDCO Rapid and TEE Against Thermodilution Technique in Cardiac Surgery
Measurement of the cardiac output is one of the important hemodynamic monitoring tools in cardiac surgery. It helps determine the type of medications needed to maintain optimal hemodynamic status in the entire perioperative…
- Trial name
- NCT02511457
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Iowa
Liver Transplantation (LT), End-stage Liver Disease (ESLD)
Restrictive Fluid Management In Liver Transplantation (REFIL)
The goal of the REFIL-2 study is to evaluate the effectiveness of a low splanchnic blood volume restrictive fluid management strategy (a strategy that involves limiting fluid administration and prioritizing the use of medications…
- Trial name
- REFIL-2 (NCT07695363)
- Testing
- Low splanchnic blood volume restrictive fluid management strategy, Phlebotomy, Optimized cardiac output liberal fluid management strategy
- Where
- 4 sites in Canada
- Volunteers
- 866 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Cardiac Output, Low
Effects of Inspiratory Flow Waveforms on Preload
The clinical usefulness of inspiratory flow pattern manipulation during mechanical ventilation remains unclear. The aim of this study was to investigate the effects of different inspiratory flow waveforms, i.e.
- Trial name
- NCT01892696
- Testing
- varying inspiratory flow waveforms
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- Military Hospital of Tunis
Cardiac Failure, Low Cardiac Output Syndrome
Landiolol in Mitral Valve Surgery
Chronic mitral regurgitation is the most common valvular abnormality worldwide, it occurs in 10% of the general population and its prevalence increases with age.
- Trial name
- LUNA (NCT06793670)
- Testing
- Landiolol
- Where
- 13 sites in Italy
- Volunteers
- 1,500 people
- Sponsor
- Università Vita-Salute San Raffaele
Cardiac Surgery, Low Cardiac Output
Is There a Correlation of Natriuretic Propeptide Type B With an Intraoperative Low Cardiac Output?
Low output syndrome is a common complication in patients undergoing cardiac surgery. Its incidence was reported to be 2 to 6%. Morbidity and mortality of low output syndrome is high and the costs for treating the disease are…
- Conditions
- Cardiac Surgery, Low Cardiac Output, Natriuretic Peptide B
- Trial name
- NCT00586027
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Klinikum Ludwigshafen
Fluid Overload, Fluid Loss
Atrial Natriuretic Peptide in Assessing Fluid Status
Biomarkers can play a significant role in fluid status assessment intraoperatively.
- Conditions
- Fluid Overload, Fluid Loss, Volume Overload, Cardiac Disease
- Trial name
- NCT05070819
- Testing
- pro-ANP
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Petrovsky National Research Centre of Surgery
Coronary Artery Disease, Low Cardiac Output Syndrome
Anesthesia Standard Operating Procedure During On-pump Coronary Artery Bypass Grafting
Background: Despite improvements in surgical and anesthesia procedures over the past 15 years complications during cardiac surgery still remain high. Bridgewater B et al.
- Conditions
- Coronary Artery Disease, Low Cardiac Output Syndrome, Atrial Fibrillation, Postoperative Complications
- Trial name
- NCT05514652
- Testing
- Low opioid anesthesia
- Where
- Ukraine
- Volunteers
- 120 people
- Sponsor
- Heart Institute, Ministry of Health of Ukraine
Shock, Cardiogenic, Surgery
Validity of Cardiac Output Measurement Using Niccomo Device After Cardiac Surgery
Cardiac surgery is at high risk of low cardiac output syndrome after procedure. Monitoring cardiac function, and especially cardiac output, is important to identify cardiovascular dysfunction and to introduce and adjust optimal…
- Conditions
- Shock, Cardiogenic, Surgery, Output, Low Cardiac
- Trial name
- Niccomo-Card (NCT04643509)
- Testing
- Niccomo
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Rouen