Clinical trials: Low Dose
Seborrhea, Seborrheic Dermatitis
Efficacy and Safety of Low-dose Oral Isotretinoin for Seborrhea
Oral isotretinoin is the gold standard drug to treat moderate to severe acne. Other indications like seborrhea, seborrheic dermatitis have been suggested.
- Conditions
- Seborrhea, Seborrheic Dermatitis, Quality of Life
- Trial name
- NCT01139749
- Testing
- oral isotretinoin, salicylic acid and ciclopirox olamine
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Follicular Lymphoma
A Phase II Trial of Intermediate Radiation Dose For Lymphoma
The purpose of this study is to determine the optimal radiation dose fractionation regimen for low grade follicular lymphoma. It is hypothesized that the complete response rate with the use of 12 Gy in 6 daily fractions is 80%…
- Trial name
- NCT05284825
- Testing
- 12 Gy in 6 daily fractions
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Measles
Early Two-dose Measles Vaccination Trial
The specific aims are to examine in Guinea-Bissau: whether the standard titre Schwarz (SW) or standard-titre Edmonston-Zagreb (EZ) measles vaccine will be the best vaccine strain for use in a routine one-dose measles vaccination…
- Trial name
- NCT00168558
- Testing
- Measles vaccine
- Where
- Guinea-Bissau
- Volunteers
- 5,879 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Lung Cancer
National Lung Screening Trial (NLST) Screening
RATIONALE: Effective screening tests should help doctors detect lung cancer early and plan curative treatment. It is not yet known whether low-dose helical computed tomography (LDCT) screening is more effective than chest…
- Trial name
- NLST (NCT00047385)
- Testing
- low-dose helical computed tomography, chest radiography
- Where
- 33 sites in United States
- Volunteers
- 53,454 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Risk Factors, Polypharmacy
Telecommunication Technology-based Online Survey
The aim of this study is to identify and assess new health-associated risk factors, including clinical-pharmacological risk factors. The cohort is built using telecommunication approaches.
- Conditions
- Risk Factors, Polypharmacy, Drug Interactions, Self Medication
- Trial name
- NCT06159699
- Testing
- Online Survey, Genetic Testing
- Where
- Russia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Genotoxicity, Cytotoxicity
Assessment of Cytotoxicity, Genotoxicity
Goal: The goal of this observational study is to evaluate the genotoxic and cytotoxic effects of OPG and CBCT on exfoliated buccal mucosal cells Main question: Does CBCT cause greater genotoxic and cytotoxic effects on buccal…
- Conditions
- Genotoxicity, Cytotoxicity, Ionizing Radiation Exposure, Dental X-Ray Exposure
- Trial name
- NCT07330401
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yaxin Wang
BRCA Mutation, PALB2 Gene Mutation
Low Dose TamOxifen and LifestylE Changes for bReast cANcer prevenTion
Circulating levels of Sex Hormone Binding Globulin (SHBG) are significantly associated with a decreased risk of breast cancer. The main aim of this clinical trial is to verify whether Low Dose Tamoxifen (LDT) increases…
- Conditions
- BRCA Mutation, PALB2 Gene Mutation, Ductal Carcinoma in Situ, Lobular Carcinoma in Situ
- Trial name
- TOLERANT (NCT06033092)
- Testing
- Tamoxifen 10 mg Tablet, Intermittent caloric restriction, Step counter Device
- Where
- 4 sites in Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- European Institute of Oncology
Anesthetic, Sedative or Analgesic Complications in Labor or Delivery
Trial of Onset of Epidural Pain Relief With Low Dose Bupivacaine and Different Doses of Fentanyl in Laboring Women
Epidural analgesia is the most effective form of labor pain relief. Low doses of local anesthetic (freezing solutions) in combination with opioids (narcotics) are commonly used as epidural solutions to provide pain relief.
- Trial name
- NCT02004899
- Testing
- Fentanyl
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lung Cancer (Diagnosis), Non-Small Cell Lung Cancer
Lung Cancer Screening in Population Who Had Never Smoked
Study design: prospective, single arm. Objectives: survey lung cancer detection rate of low-dose computed tomography (LDCT) screening in individuals who had never smoked.
- Conditions
- Lung Cancer (Diagnosis), Non-Small Cell Lung Cancer, Small Cell Carcinoma of Lung, Screening Strategy
- Trial name
- NCT07383454
- Testing
- Low dose computed tomography
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Low-Dose High-Frequency CPR Training
Low-Dose, High-Frequency CPR Training in Pediatric Emergency Nurses
Life-threatening conditions such as respiratory failure, shock, and cardiac arrest require rapid recognition and timely intervention in pediatric emergency settings.
- Trial name
- LDHF CPR Peds (NCT07508085)
- Testing
- Low-Dose High-Frequency CPR Training, Massed CPR Training
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara University
Post-Traumatic Headache, Acute Pain
Titrated Versus High and Low Dose Nebulized Morphine to Reduce Pain in Emergency Settings
The investigators test a different technique using morphine to improve pain relief in patient visiting the emergency department with acute trauma pain, for this we are comparing three different methods of morphine administration…
- Trial name
- TIMORNEB (NCT02200185)
- Testing
- IV titrated morphine, Low dose nebulised morphine, High dose nebulised morphine
- Where
- Tunisia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Monastir