Clinical trials: Low Mood
Depression, Mood
Intern Health Study 2022 and 2023
The aim of this trial is to evaluate the efficacy of an intervention (delivered through a smartphone) for improving the mood, physical activity, and sleep of medical interns.
- Conditions
- Depression, Mood, Sleep, Physical Activity
- Trial name
- IHS (NCT05436145)
- Testing
- Intern Health Study behavioral change mobile notification
- Where
- United States
- Volunteers
- 2,562 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Anxiety Depression
Development of the Neuroimaging Biomarker-based Prediction Model of Anxiety-related Disorders: Effect of Mindfulness-based Cognitive Therapy Using Neuroscience on the Brain
The purpose of this study designed a randomized clinical trial is to determine the efficacy of an 8-week mindfulness-based cognitive therapy using neuroscience (NMBCT) to reduce anxiety or depressive symptoms among adult…
- Trial name
- NCT05911412
- Testing
- Mindfulness-based cognitive therapy using neuroscience (NMBCT)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- CHA University
Major Depressive Disorder, Schizophrenia
Disorder-tailored Transcranial Direct Current Stimulation (tDCS) of the Prefrontal Cortex
Major depressive disorder (MDD) is a common, recurrent, and frequent chronic disorder. Among others, deficient cognitive control over emotional distraction is a central characteristic of MDD (Ochsner \& Gross 2005; Disner et al.
- Trial name
- MRSDC1 (NCT02715128)
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Stress, Emotional, Stress-related Mental Disorders
School-Based Intervention to Enhance Resilience and Stress Coping in Rural Chinese Adolescents
This study aims to evaluate the effectiveness of school-based psychological interventions in improving stress resilience and coping skills among adolescents in rural China.
- Trial name
- EASY (NCT07115186)
- Testing
- Psychoeducation, guided written therapy, wait-list condition
- Where
- China
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Peking University
Covid19, Post Traumatic Stress Disorder
Post-traumatic Stress, Signs of Depression and Burnout Syndrome Among Nursing Home Staff in Occitanie During the COVID-19 Pandemic
Nursing home staff face multiple stresses during the Covid-19 pandemic including personal risk of infection, risk of transmission of the virus to residents and relatives, and risk of witnessing end-of-life scenarios under…
- Conditions
- Covid19, Post Traumatic Stress Disorder, Anxiety, Depressive Disorder
- Trial name
- PSY-COEHPAD-OC (NCT04916275)
- Testing
- Cognitive tests
- Where
- 3 sites in France
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Major Depressive Disorder
Magnetic Resonance Imaging Study of Geriatric Depression
The purpose of this study was to use Magnetic Resonance Images to further our understanding of predictors and markers of treatment response and non-response in geriatric depression.
- Trial name
- NCT00245557
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Bipolar Depression
Lamotrigine Therapy in Geriatric Bipolar Depression
We propose to study the efficacy and tolerability of lamotrigine in the treatment of older adults with bipolar depression and to compare measures of brain energy metabolism between older subjects with bipolar depression and…
- Trial name
- NCT00720473
- Testing
- Lamotrigine
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Compare Diabetes Distress and Depression
Comparative Study About the Influence of Diabetes Diatress and Depression on Treatment Adherence in Chinese Type 2 Diabetes Patients
An effective treatment adherence was a key to make the treatment success, some reports had shown that psychologicl factors impact patients adherence seriously,however, in China, the researches were only limited to depression and…
- Trial name
- NCT01755351
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shandong Provincial Hospital
Depression, Postpartum
Prevention of Postpartum Depression in Low-Income Women
This study will determine whether a prevention program reduces the incidence of postpartum depression in pregnant women who receive public assistance and are at risk for postpartum depression.
- Trial name
- NCT00053651
- Testing
- Survival Skills for Moms with New Babies
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
T2DM
The Imaging Genetic Study of Type 2 Diabetes and Depression
To investigate the structural/functional abnormalities and the possible genetic endophenotypes of in the Type 2 Diabetes Patient With Depression.
- Trial name
- NCT03564431
- Testing
- Magnetic resonance
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kunming Medical University
PostPartum Depression
The Effect of Exercise on Preventing PostPartum Depression
The purpose of this study is to examine the feasibility and efficacy of an exercise intervention for the prevention of postpartum depression.
- Trial name
- NCT00961402
- Testing
- Wellness Control, Exercise Intervention
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Psychological Stress, Anxiety
Mindfulness Training in U.S. Army Cohorts
This project aims to contextualize delivery of mindfulness training to U.S. Army personnel, evaluate its effectiveness on measures of executive functions and psychological well-being, and determine best practices for its delivery.
- Conditions
- Psychological Stress, Anxiety, Post Traumatic Stress Disorder, Depression
- Trial name
- NCT03310112
- Testing
- 4-week MBAT, 2-week MBAT
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami
Anxiety, Depression
Attention Training Technique and Mindful Self-Compassion
The design of the study is a randomized controlled trial. A total of 80 students with self-reported symptoms of stress/anxiety/depression will be invited to take part in a 3-session course consisting of either attention training…
- Conditions
- Anxiety, Depression, Stress, Psychological
- Trial name
- NCT03332381
- Testing
- Attention training technique, Mindful self-compassion
- Where
- Norway
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Depression Disorder
Study on the Antidepressant Effects and Mechanism of Action of Cang-ai Volatile Oil Based on Near-Infrared Functional Brain Imaging and the NT-Trk Signalling Pathway
This project plans to recruit 60 patients with depression, randomly assigning them to either the CAVO group or the bergamot essential oil group, with 30 participants in each.
- Trial name
- NCT07384312
- Testing
- Cang-ai Volatile Oil, Bergamot Essential Oil
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dongdong Qin
Adolescent Depression
Adolescent Mood During Puberty and Testosterone
Starting at puberty, female adolescents are nearly three-times more likely to develop internalizing disorders, like depression, while male adolescents are two-times more likely to develop externalizing disorders, like attention…
- Trial name
- AMPT (NCT06072677)
- Testing
- Healthy Minds Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Depression, Senile Dementia
Short-term Effects of an Inpatient Geriatric Consultation Team on Geriatric Syndrome Patients
Patients admitted to acute ordinary wards in a medical center in Southern Taiwan from an elder-integrated outpatient department or emergency room from January 2017 to December 2017 were included if they met the following…
- Trial name
- NCT03840759
- Testing
- inpatient geriatric consultation team
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Perinatal Depression
A Chinese Version of the Thinking Health Program for East Asian Pregnant Immigrant People in Canada
The goal of this study is to determine the feasibility of using a psychosocial intervention culturally adapted in China to support perinatal mental well-being of Chinese immigrant pregnant women in Canada.
- Trial name
- NCT06446089
- Testing
- THP: cognitive behavior therapy and behavioral activation
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Shahirose Sadrudin Premji
Depression Relapse in Women Undergoing Fertility Treatment
Symptom Tracking in Assisted Reproductive Technologies
This study assesses risk factors for depressive relapse in women undergoing fertility treatment with histories of major depressive disorder (MDD) or bipolar disorder.
- Trial name
- START (NCT01746797)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Stress, Psychological Stress
Examine the Effects of Mindfulness in Woman With a History of Child Adversity
The aim of this pilot Randomized Controlled Trial (RCT) is to test whether brief mindfulness-based practices will improve well-being and health in women (age 30-50) with a history of early life adversity.
- Conditions
- Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms
- Trial name
- EMMA (NCT05255380)
- Testing
- Mindfulness and compassion-based practices; approximately 5-10 minutes two times/day, Mindful awareness and reporting of current thoughts and feelings, 2 times/day
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Depression, Postpartum
The Correlation Between Prelabor Analgesic Plan and Actual Labor Analgesia With Satisfaction, Postpartum Depression, and Breast Feeding Success
In this study the investigators would like to evaluate how prelabor analgesic plan and actual labor analgesia effects the labor satisfaction, breastfeeding success, and whether or not it reduces postpartum depression.
- Trial name
- NCT02495350
- Testing
- Questionarie
- Where
- Israel
- Volunteers
- 1,954 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
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