Clinical trials: Low Vision
Age-related Macular Degeneration
Visual Remapping to Aid Reading With Field Loss
Reading performance in patients with Central Vision Loss and age matched controls with artificial scotomas will be measured with and without different kinds of remapping of missing text to different parts of the visual field.
- Trial name
- NCT03848663
- Testing
- Traditional Remapping, Personalized Remapping
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Open-angle Glaucoma, Low Tension Glaucoma
Waveform Analysis of the Doppler Curve of Ophthalmic Arteries in Glaucoma Patients
Color Doppler Imaging (CDI) has been providing information about ocular blood flow over the past decades. This non-invasive procedure based on ultrasound technique has identified increased resistance and decreased systolic blood…
- Trial name
- NCT01487655
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stroke, Ischemic, Hemianopia, Homonymous
Statistical Learning as a Novel Intervention for Cortical Blindness
This project aims to develop a novel visual training paradigm for use in visually-intact participants and those sufferings from stroke-induced visual impairments.
- Conditions
- Stroke, Ischemic, Hemianopia, Homonymous, Hemianopsia, Occipital Lobe Infarct
- Trial name
- NCT06578117
- Testing
- Vision Training and Learning Task
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Low Vision in Children
Research and Development of Reading Visual Aids for Low-Vision Individuals Based on Virtual Reality Technology
Low vision substantially impairs reading ability and educational participation in adolescents. Existing assistive technologies, including optical magnifiers and electronic visual aids, are often limited by fragmented system…
- Trial name
- NCT07703449
- Testing
- VR-Based Intelligent Reading Aid, Natural Vision Reading (No Assistive Device)
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Macular Degeneration, Age-Related, Diabetic Retinopathy
Visual Enhancement Device in Low Vision Patients
This study will be a prospective, non-randomized study of low-vision individuals diagnosed with either age-related macular degeneration (AMD) or diabetic macular edema with ETDRS visual acuity from 20/60 to 20/400 in both eyes…
- Trial name
- Evergaze (NCT03794752)
- Testing
- Head-Mounted Visual Enhancement Device
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Dry Age-related Macular Degeneration, Vision Impairment and Blindness
Vision Improvement for Legally Blind Dry AMD Patients
This retrospective observational study is intended to assess the feasibility of using a nonsignificant risk device for vision improvement for legally blind dry AMD patients.
- Trial name
- NCT04875234
- Testing
- Clear-K Low Vision Aid Treatment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Optimal Acuity Corporation
Visual Impairment
Validity of at Home Visual Acuity Measurements for Telemedicine During Corona Virus (COVID-19) Pandemic
Prompted by the current COVID-19 pandemic, the American Academy of Ophthalmology has recommended the use of telemedicine to continue ophthalmic care while maintaining patient and provider social distancing.
- Trial name
- NCT04391166
- Testing
- Non invasive visual acuity testing
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Amyotrophic Lateral Sclerosis
Relationship Between Neurological Disability and Visual Impairment in Patients With ALS or Friedreich's Ataxia
The aim of this study is to obtain an early biomarker of amyotrophic lateral sclerosis and Friedreich's Ataxia which allows to diagnose the disease in an initial stage and to follow up the patient with optic coherence tomography…
- Trial name
- NCT03285204
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Jose Luis Urcelay Segura
Refractive Error - Myopia Axial, Astigmatism
Refractive Accuracy of "2WIN" and Portable Autorefractors
Youth and some adults have photoscreening refractions and hand-held auto refraction before cycloplegia refraction during new and follow up eye examinations.
- Conditions
- Refractive Error - Myopia Axial, Astigmatism, Accomodation, Visual Impairment
- Trial name
- NCT04249505
- Testing
- "2WIN" Photoscreener, "Plusoptix A12", "Retinomax"
- Where
- United States
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- Alaska Blind Child Discovery
Mean Blur Ratio
Isometric Exercise in NTG
Glaucoma is the second leading cause of blindness worldwide. Literature shows increasing evidence that dysfunction of ocular microcirculation in the optic nerve influences the progression of glaucoma.
- Trial name
- NCT03921372
- Testing
- Isometric exercise
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Augenabteilung Allgemeines Krankenhaus Linz
Visual Impairment, Age-Related Macular Degeneration
A Virtual Reality Platform Simulating Visual Impairment for Testing of Electronic Travel Aids and Performing Orientation and Mobility Training
In this study, the study team utilize virtual reality (VR) to simulate visual impairments of different types and severity in healthy subjects.
- Conditions
- Visual Impairment, Age-Related Macular Degeneration, Diabetic Retinopathy, Glaucoma
- Trial name
- NCT05135195
- Testing
- In-House Developed VR Platform - AMD, DR, Glaucoma, In-House Developed VR Platform - Glaucoma
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Corneal Astigmatism
Treatment of Vision Disturbances Due to Corneal Irregularities by Trans-epithelial Optical Phototherapeutic Keratectomy (TE-oPTK)
This study sets out to evaluate the EpiMaster application software for use in predicting the refractive change induced by a trans-epithelial phototherapeutic keratectomy (TE-PTK) procedure in eyes with irregularly irregular…
- Trial name
- NCT03841253
- Testing
- Trans-epithelial PTK, Trans-epithelial PTK (retrospective data collection), EpiMaster Application Software
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- London Vision Clinic
Choroideremia
The Dark-Adapted Retinal Function Response in Choroideremia (DARC) Study
Choroideremia (CHM) is an inherited retinal disorder that causes progressive vision loss, ultimately leading to complete blindness.
- Trial name
- DARC (NCT05045703)
- Testing
- Vitamin A palmitate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Low Vision
Community Access Through Remote Eyesight (CARE) Study
Study is a randomized clinical trial evaluating the efficacy of novel mobile application technologies (including Seeing AI, Aira, and Supervision+) to improve quality of life in older adults with low vision by expanding community…
- Trial name
- CARE (NCT04926974)
- Testing
- Low Vision Rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- New England College of Optometry
Low Vision, Age Related Macular Degeneration
Early Feasibility Study Using IOPCL MAG to Improve Near Vision in ARMD Subjects
This early feasibility study aims to improve near vision in subjects 55 years or older who have a clinical diagnosis of Age-Related Macular Degeneration.
- Trial name
- NCT04984590
- Testing
- IOPCL AMD MAG
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- OnPoint Vision Inc
Amblyopia, Child
Early Vision Screening in High-risk Children
To evaluate the effect of early vision screening with automated photorefraction device in high risk children
- Trial name
- NCT02678468
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Primary Open Angle Glaucoma, Ocular Hypertension
Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor Imaging
Glaucoma is among the leading causes for blindness in the western world. Elevated intraocular pressure (IOP) has been identified as the most important risk factor.
- Conditions
- Primary Open Angle Glaucoma, Ocular Hypertension, Normal Tension Glaucoma
- Trial name
- NCT01864317
- Testing
- 7-Tesla MRI, Optical Coherence Tomography, Heidelberg Retina Tomography
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Vision Loss Partial, Vision; Loss, Both Eyes
Effect of Visual Retraining After Stroke
This project is intended to collect data using standard clinical tests and psychophysics to quantify the effect of visual cortical damage on the structure of the residual visual system, visual perception, spatial awareness, and…
- Conditions
- Vision Loss Partial, Vision; Loss, Both Eyes, Hemianopia Homonymous, Hemianopia
- Trial name
- urochester (NCT06121219)
- Testing
- Training in the Blind Field
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Presbyopia, Low Vision
Development and Validation of a Digital Optotype for Near Vision in Greek Language.
Primary objective of our study is to develop and validate a computer-based digital near-vision optotype based on the Greek version of the print MNREAD.
- Conditions
- Presbyopia, Low Vision, Near Vision
- Trial name
- DeDART (NCT04242836)
- Testing
- MNREAD testing
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
AI (Artificial Intelligence), Mammary Cancer
Experiment on the Use of Innovative Computer Vision Technologies for Analysis of Medical Images in the Moscow Healthcare System
It is planned to integrate various services based on computer vision technologies for analysis of the certain type of x-ray study into Moscow Unified Radiological Information Service (hereinafter referred to as URIS).
- Conditions
- AI (Artificial Intelligence), Mammary Cancer, Lung Cancer, X-Rays; Lesion
- Trial name
- NCT04489992
- Where
- Russia
- Volunteers
- 133,000 people, healthy volunteers welcome
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department