Clinical trials: Low Vision
Blindness, Visual Impairment
iReach: a Rehabilitative Medical Device
The broad goal of this clinical trial is to demonstrate whether a one-month rehabilitative training with our medical device, iReach, can promote the recovery of spatial and sensorimotor abilities and the cortical reorganization…
- Trial name
- NCT06334614
- Testing
- iReach
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Istituto Italiano di Tecnologia
Normal Tension Glaucoma
IOP Lowering Effects of Topical Anesthetics Used Frequently in the Ophthalmology Clinic
The primary purpose of this study is to determine whether topical ophthalmic anesthetics lower the intraocular pressure in the eye.
- Trial name
- NCT01254149
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Normal-Tension Glaucoma
Pilot Study on Ambulatory Intraocular Pressure and Blood Pressure Monitoring in Glaucoma
Purpose: To study the feasibility of a larger study by determining the tolerability of measuring blood pressure (BP) and intraocular pressure (IOP) over 24 hours in an ambulatory fashion with automatic devices.
- Trial name
- NCT01912599
- Testing
- Sensimed Triggerfish, Blood Pressure
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Macular Degeneration
Investigating Optical and Neural Causes of Vision Loss
With the aging of the population, the prevalence of age-related macular degeneration (AMD) eye disease has resulted in a large number of people suffering from central vision loss.
- Trial name
- NCT00926913
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Central Vision Loss From Macular Diseases
Training to Modify Fixational Eye Movements for Optimizing Visual Performance in People With Central Vision Loss
People with central vision loss almost all have exaggerated fixational eye movements when compared with people with normal vision (e.g. larger amplitudes of microsaccades and ocular drifts).
- Trial name
- NCT06670989
- Testing
- Fixation training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Visual Impairment, Age-Related Macular Degeneration
A Virtual Reality Platform Simulating Visual Impairment for Testing of Electronic Travel Aids and Performing Orientation and Mobility Training
In this study, the study team utilize virtual reality (VR) to simulate visual impairments of different types and severity in healthy subjects.
- Conditions
- Visual Impairment, Age-Related Macular Degeneration, Diabetic Retinopathy, Glaucoma
- Trial name
- NCT05135195
- Testing
- In-House Developed VR Platform - AMD, DR, Glaucoma, In-House Developed VR Platform - Glaucoma
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Near Infrared Spectroscopy
Cerebral Oximetry in Newborns - Comparing INVOS 5100 and FORE-SIGHT Cerebral Oximeters
Regional tissue oxygenation (rStO2) can be monitored by near infrared spectroscopy. The commercial devices FORE-SIGHT (CASMED) and INVOS (COVIDIEN) will be used simultaneously to test for their relative sensitivity for low oxygen…
- Trial name
- NCT01665287
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Vision Impairment
Providing Access to the Visual Environment
Providing Access to the Visual Environment is a pediatric low vision grant which has the ability to provide comprehensive, interdisciplinary low vision rehabilitation services to every child in Tennessee with a vision impairment.
- Trial name
- NCT00341744
- Where
- United States
- Volunteers
- 795 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Retinal Disease, Visual Impairment
Repeatability of Electroretinogram and Visual Evoked Potential
To assess repeatability of electroretinogram and visual evoked potential in clinical practice
- Conditions
- Retinal Disease, Visual Impairment, Vision Disorders
- Trial name
- NCT05334875
- Testing
- Electroretinogram (ERG), Visual evoked potential (VEP)
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Benha University
Sensory Integration Disorder
Sensory Integration for Infants With Cortical Visual Impairment
Our study examines the effect of sensory integration training on sensory, motor and oculomotor skills in infants with cortical vision impairment .
- Trial name
- NCT05431647
- Testing
- Sensory integration therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder)
24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring
The goal of this clinical trial is to learn if a new contact lens device can record patterns in eye pressure for 24 hours in adults with glaucoma and in healthy participants.
- Conditions
- Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder), Ocular Hypertension, Ocular Hypertension (OH)
- Trial name
- NCT06689696
- Testing
- miLens system
- Where
- 3 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Smartlens, Inc.
Blindness
Virtual Reality Mobility Training System for Veterans With Vision Loss
This is a two-year proof-of-concept study to evaluate a new Virtual Reality (VR) "holographic" sound system for use as an audiological Orientation and Mobility (O\&M) training tool
- Trial name
- NCT00333879
- Testing
- Virtual Sound System
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Quality of Life (QOL), Depression
Body-Mind-Spirit Action Group on the Well-being
Primary Purpose: To evaluate the effectiveness of a culturally adapted BMS group intervention on holistic well-being, depressive symptoms, sleep parameters, and quality of life in individuals with visual impairment.
- Trial name
- BMS (NCT07105761)
- Testing
- Body-Mind-Spirit
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Taipei City Hospital
Normal Tension Glaucoma
Magnetic Resonance Imaging of Patients With Normal Tension Glaucoma
The purpose of this study is to study the occurrence rate of masses such as brain tumors in patients with newly diagnosed Normal Tension Glaucoma.
- Trial name
- NCT00175786
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Stroke, Visual Defects
Differentiation of Human Body Balance Disorders
Our research aims to analyze the possibilities of functional assessment of imbalances in the human body. Using the available, commonly known and used tests and devices for objective examination of static and dynamic body balance…
- Conditions
- Stroke, Visual Defects, Labyrinth Diseases, Cervical Spine Degenerative Disease
- Trial name
- NCT07395180
- Testing
- Patients after stroke, Patients with posterior columns of the spinal cord, Patients with labyrinth diseases
- Where
- Poland
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Military Institute od Medicine National Research Institute
Pituitary Adenoma, Visual Impairment
Clinical Study of Structural and Functional Evaluation of the Visual Pathway
Sellar area tumors such as pituitary adenoma, craniopharyngioma and meningioma, etc, commonly lead to visual impairment symptoms.
- Conditions
- Pituitary Adenoma, Visual Impairment, Sellar Tumor, Neuroimaging
- Trial name
- NCT03591315
- Testing
- resting state fMRI, visual tasking state fMRI, diffusion tensor imaging
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Visual Impairment
Virtual Assistance for Daily Living: Neurophysiological and Functional Effects in Low Vision
This study aims to investigate how visual impairment affects neurophysiological and biomechanical responses during real-world navigation and daily activities, with a focus on the rehabilitative feasibility and impact of assistive…
- Trial name
- NCT07442461
- Testing
- VIS4ION Platform
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Low Vision Aids
Tactile Low Vision Labeling of Ophthalmic Drops
The purpose of this study is an evaluation of a tactile labeling strategy developed in the Ophthalmology Clinical Research Center at University of Texas Medical Branch (UTMB) in collaboration with the UTMB Maker Space to improve…
- Trial name
- NCT04483882
- Testing
- Tactile Labels for Drug identity and dose frequency
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Visual Impairment
Artificial Intelligence (AI) - Assisted Visual Impairment Screening Model: Community-based Implementation and Evaluation of Performance, Feasibility and Costs.
The goal of this observational study is to evaluate the performance, operational efficiency, acceptability, feasibility, and cost-effectiveness of an AI-assisted screening model for visual impairment in a community setting.
- Trial name
- NCT06877988
- Testing
- AI
- Where
- Singapore
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Singapore Eye Research Institute
Primary Open Angle Glaucoma, Ocular Hypertension
Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor Imaging
Glaucoma is among the leading causes for blindness in the western world. Elevated intraocular pressure (IOP) has been identified as the most important risk factor.
- Conditions
- Primary Open Angle Glaucoma, Ocular Hypertension, Normal Tension Glaucoma
- Trial name
- NCT01864317
- Testing
- 7-Tesla MRI, Optical Coherence Tomography, Heidelberg Retina Tomography
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna