Clinical trials: Low-Level Laser Therapy
Malocclusion
OrthoPulse 2.0 and 2.1 Feasibility Evaluation
OrthoPulse is a device that uses near-infrared light therapy in order to decrease orthodontic treatment time. The aim of this study is to evaluate OrthoPulse products modified with extended arrays, OrthoPulse 2.0 and OrthoPulse…
- Trial name
- BX13 (NCT03683017)
- Testing
- OrthoPulse 2.0, OrthoPulse 2.1, Invisalign 3.5 Day Wear
- Where
- 7 sites in United States, Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Oral Lichen Planus
Low Level Laser Therapy With Injectable Platelet Rich Fibrin in Management of Oral Lichen Planus
The Injectable PRF (i-PRF) is a variant of PRF, which is a liquid blood derivative rich in leukocytes and acts as a growth factor release, with its potential anti-inflammatory role, it may alleviate the symptoms of OLP.
- Trial name
- NCT07846891
- Testing
- Injectable Platelet Rich Fibrin, Low Level Laser Therapy, Triamcinolone acetonide (injection)
- Where
- 2 sites in Egypt
- Volunteers
- 39 people
- Sponsor
- Ain Shams University
Photoaging
Combination Versus Laser Treatment Only
Our objective is to determine the effects of (1) basic skin care regimen + "active" (Lytera 2.0) vs. (2) basic skin care regimen only, both groups combined with laser, on the appearance of skin tone and photo-aging on the face.
- Trial name
- NCT03661697
- Testing
- Laser Therapy, Basic Skin Care Regimen, Lytera
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Miami
Insomnia, Anxiety
Evaluation of Physiological Effects Induced by Low Level Light Irradiation on the Acupoints of the Hand
The goal of this clinical trial is to determine if low-level laser therapy (LLLT) and LED-based low-level light therapy (LLLT) are effective in inducing relaxation and improving sleep quality and anxiety levels in individuals…
- Conditions
- Insomnia, Anxiety, Acupuncture, Low-level Laser Therapy
- Trial name
- Acupuncture (NCT07190417)
- Testing
- LEDs and laser light
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Photobiomodulation Therapy, Low Level Laser Therapy
Photobiomodulation Therapy on Pain and Range of Motion Following Flexor Tendon Repair
The purpose of the study was to evaluate the therapeutic effect of low-level laser in improving pain and ROM following flexor tendon repair surgery.
- Conditions
- Photobiomodulation Therapy, Low Level Laser Therapy, Flexor Tendon Rupture, Flexor Tendon Repair
- Trial name
- NCT06761950
- Testing
- Low Level laser therapy, medical treatment, physical therapy program
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Cairo University
Subacromial Impingement Syndrome
Physical Therapy in Shoulder Impingement Syndrome
The aim of this study is to evaluate the effects of low-level laser therapy (LLLT) and therapeutic ultrasound combined with home-based exercise in comparison with home-based exercise alone in patients with subacromial impingement…
- Trial name
- NCT04779190
- Testing
- Low-level laser therapy, Therapeutic ultrasound, Home-based exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Diabetes
Effects of Electromagnetic Therapy Versus Laser Therapy on Peripheral Diabetic Neuropathy
This study are to: Evaluate effect of magnetic therapy on peripheral neuropathy in diabetic patients. Evaluate effect of laser therapy on peripheral neuropathy in diabetic patients.
- Trial name
- NCT03049605
- Testing
- Magnetic therapy, laser therapy, Only medical treatment
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Wounds
Low-level Laser Therapy in Enhancing Wound Healing and Preserving Tissue Thickness
Objective: The aim of this study was to determine the effects of Low Level Laser Therapy (LLLT) on wound healing at Free Gingival Graft donor sites (FGGDS).
- Trial name
- NCT02865902
- Testing
- Low-Level Laser Therapy by Ezlase; Biolase®
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Low Level Laser and Occlusal Splint
Prospective Investigation of the Effects of Different Treatment Techniques on Myofascial Trigger Points in Patients With Temporomandibular Dysfunction (TMD)
In the literature, there are no studies comparing the use of occlusal splint and Low Level Laser (LLL) in the treatment of Temporomandibular Disfunction (TMD) and including Ultrasonography (USG) in these parameters.
- Trial name
- NCT04456946
- Testing
- Low Level Laser Therapy, Occlusal Splint Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Prosthesis-Related Infections, Equipment Failure
Medico-economic Evaluation of Strategies for the Lead Extraction of Implantable Defibrillator and Pacemakers
The growing use and the expanding indications for cardiovascular implantable electronic devices (CIEDs) have been associated to an increase of device removal.
- Conditions
- Prosthesis-Related Infections, Equipment Failure, Heart Failure, Arrhythmias
- Trial name
- GAINE LASER (NCT03121183)
- Testing
- Laser sheath, Implantable Cardiac Device lead extraction
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Clermont-Ferrand
Low Level Laser Therapy, Performance
Photobiomodulation in Different Doses on Strength Capacities and Functional Performance
Background: Photobiomodulation has been explored for years, with wide clinical use for wound healing and analgesia in varied orthopedic conditions, but the number of research and clinical use has increased during the last decade.
- Conditions
- Low Level Laser Therapy, Performance, Sport
- Trial name
- NCT03860766
- Testing
- Photobiomodulation
- Where
- Brazil
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hashimoto Thyroiditis, Thyroiditis
Effect of Photobiomodulation Therapy in Patients With Hashimoto's Thyroiditis
The standard lifelong treatment for Hashimoto's thyroiditis (HT), a chronic autoimmune disease, is levothyroxine (LT4) therapy. Despite LT4 replacement therapy, patients continue to experience persistent fatigue, deterioration in…
- Trial name
- NCT06735040
- Testing
- Photobiomodulation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Temporomandibular Joint Disorder
The Effect of Low Level Laser Therapy on Improvement of Temporomandibular Joint Osteoarthritis
Temporomandibular disorder (TMD) is the major cause of nondental pain in orofacial area. Laser therapy can be considered as one of the most popular methods of pain relief in TMD patients.
- Trial name
- NCT01417650
- Testing
- Low level laser therapy
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
Cervical Disc Herniation
Efficacy of High-intensity Laser Therapy (HILT) in the Patients With Cervical Disc Herniation
The worldwide prevalence of neck pain is between 16.7-75.1%, it has been seen at an increasing rate in recent years due to sedentary living conditions.
- Trial name
- NCT05474625
- Testing
- High Intensity Laser Therapy, Ultrasound, Transcutaneous nerve stimulation (TENS)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Baskent University Ankara Hospital
Hematologic Malignancy
Efficacy of Prophylactic Low Level Laser Therapy (LLLT) Performed by Nurses for Decreasing Severity of Oral Mucositis During Hematopoietic Stem Cell (HSC) Transplantation
The LLLT has an anti-inflammatory, analgesic effect and accelerates the healing of ulcerated lesions. There are little data in the literature showing its efficacy in prevention of mucositis in cohorts of patients with…
- Trial name
- STOP MUCITES (NCT02696408)
- Testing
- Laser treatment
- Where
- 3 sites in France
- Volunteers
- 234 people
- Sponsor
- Institut de Cancérologie de la Loire
Cervicogenic Headache
Therapeutic Efficacy of Different Wavelengths of Low-Level Laser Therapy in the Treatment of Cervicogenic Headache
This study tests if low-level laser therapy (LLLT) with different light wavelengths can help people with cervicogenic headache, a type of headache caused by neck problems.
- Trial name
- WELL (NCT07163208)
- Testing
- Low-Level Laser Therapy (LLLT), Routine Physical Therapy (RPT)
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- University of Lahore
Acceleration of Tooth Movement
The Effect of Low-Level Laser Therapy on Accelerating Tooth Movement and Reducing Pain During Orthodontic Treatment
Orthodontic treatment is a common and effective approach to correcting dental malocclusions and improving oral function and aesthetics.
- Trial name
- LLLT (NCT07591948)
- Testing
- Low level laser therapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Oral Lichen Planus
Different Treatment Modalities for Oral Lichen Plan
The goal of applications of Low-Level Laser and Topical Steroid in the Management of Oral Lichen Planus is to learn if intervention can by relieve pain, decreasing inflammation, and facilitating tissue healing in20 patients who…
- Trial name
- NCT06681090
- Testing
- 0.1% topical triamcinolone Acetonide preparation "Kenacourt-A Orabase", 980 nm diode laser
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Dentinal Hypersensitivity
Comparison of LASER Therapy and Desensitizing Agents in Dentinal Hypersensitivity
This study evaluates the effectiveness of laser therapy versus desensitizing agents in reducing pain among participants with dentinal hypersensitivity conducted in Saidu College of Dentistry.
- Trial name
- NCT06759454
- Testing
- Glutaraldehyde-Based Desensetizing Agent, Low Level Laser Therapy
- Where
- Pakistan
- Volunteers
- 172 people
- Sponsor
- Kemia Gul
Circumference Reduction
Study of Low Level Laser Light Therapy on Circumference Reduction
The purpose of this study is to determine whether low level laser light therapy is effective in reducing circumference of the waist, hips, thighs and upper abdomen over a 6 week period.
- Trial name
- NCT02109107
- Testing
- Erchonia EZ6 Laser
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Erchonia Corporation