Clinical trials: Low-Level Light Therapy
Osteoarthritis, Osteoarthritis Finger
Effects of Using Custom Photobiomodulation Therapy for the Treatment of Osteoarthritis of the Fingers and Rhizarthrosis
Osteoarthrosis (OA), a multifactorial degenerative process, is responsible for joint pain and functional limitation. In the hand, more specifically in the proximal and distal interphalangeal joints of the fingers, it is one of…
- Conditions
- Osteoarthritis, Osteoarthritis Finger, Osteoarthritis Hand, Osteoarthritis Both Hands
- Trial name
- NCT05041231
- Testing
- Photobiomodulation therapy (PBT)
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- Vita Care
Myopia
Effect of Low-level Red-light on Ultra-high Myopia
100 eyes of ultra-high myopia were treated with daily low-level red-light. The age of children ranged from 3 to 16.3 years. The follow-up duration was one year.
- Trial name
- NCT06738095
- Testing
- daily low-level red-light
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Beijing Tongren Hospital
Multiple Sclerosis, Relapsing-Remitting
Photobiomodulation Therapy in Persons With Multiple Sclerosis
This study will test whether photobiomodulation therapy improves muscle endurance and decreases inflammation in persons with relapsing-remitting multiple sclerosis. We will also investigate mechanisms for any improvements.
- Trial name
- NCT03691766
- Testing
- Photobiomodulation Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Marquette University
Muscle; Fatigue, Heart, Skeletal Muscle Recovery
Infrared Low-level Laser Therapy Before Intense Progressive Running Test of High-level Soccer Players
Photobiomodulation therapy (PBMT) has recently been used to alleviate postexercise muscle fatigue and enhance muscle recovery, demonstrating positive results.
- Trial name
- NCT03803956
- Testing
- Active PBMT
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Myopia, Refractive Errors
Effect of Repeated Low-Level Red-Light Therapy on Retinal Function and Structure
The purpose of this clinical trial is to evaluate the effect of repeated low-level red-light (RLRL) therapy on the retinal function and structure among myopic teenagers.
- Conditions
- Myopia, Refractive Errors, Eye Diseases, Retina; Change
- Trial name
- NCT05597397
- Testing
- RLRL
- Where
- China
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Head and Neck Cancer, Head and Neck Neoplasms
Photobiomodulation Therapy Plus M-health in Head and Neck Cancer Patients: LAXER Study
The Photobiomodulation therapy could have positive effects on quality of life and oral health in head and neck cancer survivors post-radiotherapy. The improvement in quality of life will be maintained after a follow-up period.
- Conditions
- Head and Neck Cancer, Head and Neck Neoplasms, Xerostomia
- Trial name
- LAXER (NCT05106608)
- Testing
- Energy density photobiomodulation (7.5), Energy density photobiomodulation (3)
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Granada
AMD - Age-Related Macular Degeneration
Repeated Low-Level Red-Light Therapy in Dry Age-Related Macular Degeneration
This prospective, double-blind, randomized controlled trial aims to evaluate the efficacy and safety of repeated low-level red-light (RLRL) therapy in patients with dry age-related macular degeneration (AMD).
- Trial name
- NCT07409389
- Testing
- RLRL device
- Where
- China
- Volunteers
- 94 people
- Sponsor
- The Hong Kong Polytechnic University
Head and Neck Cancer, Head and Neck Neoplasms
Photobiomodulation Therapy in Patients With Head and Neck Cancer Post-Radiotherapy
Patients with head and neck cancer post-radiotherapy may improve their perceived and amount of saliva after a 3-month Photobiomodulation (PBM) therapy focuses on three main salivary glands (parotid, submandibular and sublingual…
- Conditions
- Head and Neck Cancer, Head and Neck Neoplasms, Xerostomia
- Trial name
- NCT05614843
- Testing
- Energy density photobiomodulation (7.5)
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Universidad de Granada
Muscle; Fatigue, Heart, Skeletal Muscle Recovery
Low Level Laser Therapy in Muscle Fatigue and Muscle Recovery
Muscle fatigue and muscle recovery after exercise are recent areas of research involving Low Level Laser Therapy (LLLT) and many factors remain unknown, such as optimal doses, power and application parameters, mechanisms of…
- Trial name
- LLLT (NCT01844271)
- Testing
- Low Level Laser (LLL)
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- University of Nove de Julho
Autism, Attention Deficit Hyperactivity Disorder
Transcranial Photobiomodulation Therapy for the Treatment of Autistic Traits in Children and Adolescents With ADHD
An open label trial to assess the safety and efficacy of transcranial photobiomodulation (tPBM) in improving autistic traits in ADHD youth.
- Trial name
- NCT04569058
- Testing
- Transcranial Photobiomodulation
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Massachusetts General Hospital
High Myopia
Efficacy and Safety of Low-Level Monochromatic Red-Light for High Myopia Control in Adults
The purpose of this clinical study is to confirm the effectiveness and safety of low-level monochromatic red-light for high myopia control in adults
- Trial name
- NCT05947019
- Testing
- Myopic amblyopia comprehensive treatment instrument, Glasses
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Incontinence Associated Dermatitis, Diaper Rash
Adjuvant Effect of Photobiomodulation in the Treatment of Incontinence-associated Dermatitis in Adults
Incontinence-associated dermatitis (IAD) is an inflammation of the skin that occurs as a result of urine or feces contact on the perineal or perigenital region in adults.
- Conditions
- Incontinence Associated Dermatitis, Diaper Rash, Photobiomodulation Therapy
- Trial name
- DAI (NCT05471180)
- Testing
- protective spray film, photobiomodulation therapy
- Where
- Brazil
- Sponsor
- University of Nove de Julho
Post-stroke Aphasia
The Effect of PBM on the Electrical Activity of the Brain in Stroke Patients
The Effect of Low-Level Light Therapy on the Electrical Activity of the Brain in Stroke Patients
- Trial name
- PBM (NCT07323823)
- Testing
- photobiomodulation (PBM), control group-receive speech therapy
- Volunteers
- 66 people
- Sponsor
- Pusan National University Yangsan Hospital
Xerostomia, Chronic Renal Failure
Effects of Photobiomodulation in Salivary Analysis of Chronic Renal Failure Patients
End-stage renal disease patients undergoing hemodialysis can present alteration in flow, concentrations and composition of saliva affecting oral health.
- Trial name
- NCT03647813
- Testing
- Photobiomodulation
- Volunteers
- 44 people
- Sponsor
- University of Nove de Julho
Pathologic Myopia
LED Red Light in Modulating Choroidal Microcirculation to Retard Retinal Atrophy in Pathological Myopia
The goal of this clinical trial is to learn if LED repeated low-level red light (RLRL) therapy works to treat pathologic myopia in adults. It will also learn about the safety of LED-RLRL.
- Trial name
- NCT07312214
- Testing
- LED red light
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Radiation
Photobiomodulation to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Head & Neck Cancer Patients
The overall purpose of this clinical study is to evaluate safety and efficacy of the MuReva Phototherapy System with a light delivery mouthpiece to reduce the severity of oral mucositis (OM) in adult patients with squamous cell…
- Conditions
- Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Radiation, Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy, Head and Neck Cancer
- Trial name
- NCT03972527
- Testing
- Photobiomodulation, Routine Oral Care and Analgesia
- Where
- 12 sites in United States
- Volunteers
- 85 people
- Sponsor
- MuReva Phototherapy Inc.
Temporomandibular Disorder, Anxiety State
Low-Level Laser Auriculotherapy in the Treatment of Myogenic Temporomandibular Disorders and Anxiety
Summary: Low-level laser auriculotherapy (LLLT-AT) is a non-invasive technique that has gained attention for managing musculoskeletal pain and anxiety.
- Trial name
- NCT07125404
- Testing
- Low-level laser auriculotherapy (LLLT-AT), Myofascial release
- Where
- Chile
- Volunteers
- 32 people
- Sponsor
- Quiropraxia y Equilibrio
Depression
Augmenting Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder With Low-Level Light Therapy
The purpose of this study is to better understand how low-level light therapy (LLLT) can be used to augment the antidepressant effects of Deprexis, an internet-based treatment program for depression, for participants with current…
- Trial name
- CBT/LLLT (NCT02898233)
- Testing
- Deprexis, Active low-level light therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas at Austin
PARKINSON DISEASE (Disorder)
Whole-Body Photobiomodulation for Motor and Cognitive Changes in Parkinson's Disease
This study aims to exploratorily evaluate the extent of motor and cognitive changes, as well as the safety, resulting from approximately 10 weeks of whole-body photobiomodulation (PBM) therapy (about three sessions per week, once…
- Trial name
- PBM (NCT07271927)
- Testing
- Photobiomodulation
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Pusan National University Yangsan Hospital
Muscle Damage
Effect of Low-level Laser Therapy on Exercise-induced Muscle Damage
Introduction: The effects of Low Level Laser Therapy (LLLT) on exercise-induced muscular damage have been studied over the last years.
- Trial name
- NCT02493556
- Testing
- LLLT before muscle damage, LLLT after muscle damage
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre