Clinical trials: Low-Level Light Therapy
Myopia, Refractive Error - Myopia
Minimum Power and Frequency of Repeated Low-level Red-light to Effectively Control Myopia Progression
To explore the minimum power and frequency of Repeated Low-level Red-light (RLRL) to control myopia progression in low-myopic children aged 8-10 years, and the rebound effect of low-myopic children after discontinuation of RLRL…
- Conditions
- Myopia, Refractive Error - Myopia, Choroidal Thickness, Retina
- Trial name
- NCT06717048
- Testing
- Repeated Low-level Red-light, Red LED
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Chronic Low Back Pain, After Lumbar Spine Surgery
Efficacy of Cognitive Functional Therapy in Individuals With Chronic Low Back Pain After Spinal Surgery
Chronic low back pain after spinal surgery is a complex and disabling condition influenced by biopsychosocial factors. Cognitive Functional Therapy (CFT) is a promising intervention targeting these multidimensional aspects.
- Conditions
- Chronic Low Back Pain, After Lumbar Spine Surgery, Failed Back Surgery Syndrome (FBSS)
- Trial name
- NCT07576062
- Testing
- CFT
- Volunteers
- 90 people
- Sponsor
- Centro Universitário Augusto Motta
Burning Mouth Syndrome
Comparison Between Two Treatments for Burning Mouth
Introduction: The management of patients with chronic burning mouth is a challenge in clinical dentistry. Objective: To compare the effect of Low Level Laser Therapy (LLLT) and Transcutaneous Electrical Nerve Stimulation (TENS)…
- Trial name
- NCT05816200
- Testing
- Low-Level Light Therapy, Transcutaneous Electric Nerve Stimulation
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Mild Cognitive Impairment (MCI), Mild Alzheimer Disease
Efficacy and Safety of Photobiomodulation Therapy in Patients With Mild Cognitive Impairment and Mild Alzheimer's Disease
The goal of this clinical trial is to learn if photobiomodulation therapy (PBMT) can help treat mild cognitive impairment and mild Alzheimer's disease in adults aged 50 to 85 years. It will also learn about the safety of PBMT.
- Conditions
- Mild Cognitive Impairment (MCI), Mild Alzheimer Disease, Dementia
- Trial name
- PBMT in MCI (NCT07835399)
- Testing
- Photobiomodulation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Jun Xu
High-level Rugby Athletes, Performance
Photobiomodulation Therapy in a Field Test With High-level Rugby Players
Background/Aim: While growing evidence supports the use of photobiomodulation therapy (PBMT) for performance and recovery enhancement, there have only been laboratory-controlled studies.
- Conditions
- High-level Rugby Athletes, Performance, Recovery
- Trial name
- NCT02588768
- Testing
- Photobiomodulation therapy (Phototherapy)
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Demodex Blepharitis, Meibomian Gland Dysfunction (MGD)
Effectiveness of Low Level Light Therapy and Intense Pulse Light on Mite Count as Adjuntive Therapies in Demodex Blepharitis Using Artificial Intelligent Program (Ai-Demodex)
Primary Objective: To evaluate the efficacy of LLLT, IPL, and IPL + LLLT in re ducing demodex count in patients with Demodex Blepharitis.
- Trial name
- Ai-Demodex (NCT07169461)
- Testing
- The blue MY MASK-E, IPL, Mechanical with pharmacological treatment
- Where
- Thailand
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Diabetic Foot Ulcer
High Intensity LED Photobiomodulation Therapy for Chronic Leg and Foot Ulcers
Diabetic and venous ulcers affect many people, and severe cases can end up in amputation and even death because of infection. In 2011, the total cost for care of diabetic foot ulcers alone, to the Canadian health care system, was…
- Trial name
- NCT04300205
- Testing
- High intensity LED light device
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Illumacell Inc.
Myopia, Progressive
Clinical Study of Light Therapy to Control Myopia Progression in Children
Low-lever red light therapy (LLLT) has been used to control myopia progression in China for a few years besides amblyopia therapy for a few decades.
- Trial name
- NCT05761379
- Testing
- Photobiomodualtion Therapy, Single vision spectacles for correction myopia
- Where
- China
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Myopia
Effects of Low-Level Red Light and Distant-Image Screen for Myopia Control in Children
This study aims to assess the efficacy and safety of daily exposure to 650-nm low-level red light (RL) and distant-image therapy (DIT) for myopia treatment.
- Trial name
- NCT06683287
- Testing
- red light and distant image screen, red light, distant image screen
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Tongren Hospital
Aging
Revitalize Cognition: Near Infrared Stimulation in Older Adults
Changes in mood and cognition are common in older adulthood. Some studies have suggested that transcranial application of near-infrared (NIR) light may have enhancing effects on cognitive and mood status in young adults and…
- Trial name
- NCT02582593
- Testing
- MedX 1116 Rehab Console
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Florida
Menstrual Cycle Disorder
Physical Performance of Women at Different Stages of the Menstrual Cycle, and Photobiomodulation Therapy
Hormonal fluctuations present during the ovarian cycle may have a strong influence on physiological and psychological aspects on physical performance in women.
- Trial name
- NCT04281446
- Testing
- Photobiomodulation
- Where
- 2 sites in Brazil
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Androgenetic Alopecia, Hair Loss
Low Level Light Device as a Primary Therapy for Androgenetic Alopecia
The purpose of this research is to study the safety and effectiveness of a light therapy device for human hair growth. This device, called the GENIX, is a type of cold, or non-heat producing light emitting diode (LED) that will…
- Conditions
- Androgenetic Alopecia, Hair Loss, Thinning Hair, Balding
- Trial name
- NCT04558242
- Testing
- Genix
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kiierr International, LLC
Myopia, Refractive Errors
Efficacy of Repeated Low-Level Red-Light Therapy in Myopia Control
The purpose of this study is to determine if repeated low-level red-light therapy can slow myopia progression in Chinese schoolchildren.
- Conditions
- Myopia, Refractive Errors, Eye Diseases
- Trial name
- NCT04073238
- Testing
- Low-level Red-light Therapy
- Where
- 4 sites in China
- Volunteers
- 264 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Low Back Pain (LBP)
Effects of Laser Therapy and Exercise in Participants With Chronic Low Back Pain
The objective of this clinical trial is to evaluate the additional effects of Laser Therapy in participants with chronic non-specific low back pain in the short and long term.
- Trial name
- NCT04287725
- Testing
- exercise + photobiomodulation therapy
- Volunteers
- 130 people
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Alopecia
LLLT for Alopecia of the Eyebrow in Women
The purpose of this research is to study the ongoing effectiveness of a light therapy device for human hair growth. This device, called the iRestore Eyebrow Device, is a type of cold, or non-heat producing light therapy system…
- Trial name
- NCT04897555
- Testing
- LLLT
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Freedom Laser Therapy, Inc.
Melasma
Treatment of Melasma With Yellow Light Compared to Tranexamic Acid
Photobiomodulation (PBM) has been suggested as an alternative treatment for Melasma, showed by the in vitro data, inhibition of the tyrosinase enzyme and reduction in the pigment content by autophagy.
- Trial name
- NCT05326997
- Testing
- Photobiomodulation group, Group control (Tranexamic acid)
- Where
- 2 sites in Brazil
- Volunteers
- 21 people
- Sponsor
- University of Nove de Julho
Orthodontic Pathological Resorption of External Root, Orthodontic Appliance Complication
Photobiomodulation and Root Resorption
Objectives: The aim of this study is to investigate the effect of photobiomodulation therapies on root resorption compared with the placebo group. Materials and Methods: 30 patients, who were admitted to the ………….
- Conditions
- Orthodontic Pathological Resorption of External Root, Orthodontic Appliance Complication, Orthodontic Tooth Movement
- Trial name
- NCT04044989
- Testing
- Laser, light-emitting diode (LED)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Myopia, Progressive, Refractive Errors
Repeated Low-Level Red-Light Therapy and Orthokeratology in Fast-progressing Myopia Control
The purpose of this multicenter randomized clinical trial is to evaluate the adjunctive effect of repeated low-level red-light therapy (RLRL) and orthokeratology (ortho-k) on myopia control in ortho-k non-responders who have…
- Conditions
- Myopia, Progressive, Refractive Errors, Eye Diseases
- Trial name
- NCT04722874
- Testing
- Ortho-k lenses, RLRL
- Where
- 3 sites in China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Head and Neck Neoplasms
Evaluation of Two Methods of Administration of Photobiomodulation in the Context of the Prevention and Treatment of Mucositis Induced by Radiotherapy, During the Treatment of Head and Neck Cancers
The aim of this feasibility, prospective, single-center trial is to compare an intra-oral Photobiomodulation (PBM) via the Caremin650TM device (NeoMedLight) and a transcutaneous PBM via the ATP 38® device (Swiss Bio Innov) in…
- Trial name
- RADIO-PBM (NCT06458517)
- Testing
- Photobiomodulation session - intraoral, Photobiomodulation session - transcutaneous
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Paul Strauss
Chemotherapy-induced Peripheral Neuropathy
Photobiomodulation Therapy in the Management of Chemotherapy-Induced Peripheral Neuropathy
This study aims to investigate the effectiveness of photobiomodulation therapy (PBM) in the management of chemotherapy-induced peripheral neuropathy (CIPN).
- Trial name
- NeuroLight 2 (NCT05763706)
- Testing
- Multiwave Locked System® (M6 laser, ASA srl, Arcugnano (VI), Italy)
- Where
- Belgium
- Volunteers
- 172 people
- Sponsor
- Jessa Hospital