Clinical trials: Lower Abdominal Pain
Cesarean Section Complications
Quality of Life and Pain Pressure Threshold in Response to Scar Release Techniques for Chronic Transverse Abdominal Scar
Postoperative scarring is one of the most common concerns among surgical patients. The incidence of abnormal scarring, i.e. keloid or hypertrophic scar formation after caesarean section (CS) is reported to be 41% .That can lead…
- Trial name
- NCT05937217
- Testing
- myofascial induction and direct scar release techniques, therapeutic ultrasound
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Other Acute Postoperative Pain
Paracetamol Versus Dipyrone After Pediatric Lower Abdominal Surgery in Children With Spinal Anesthesia
We conducted a prospective, randomized double-blind study to compare the effectiveness of intravenous paracetamol and dipyrone for preventing pain during early postoperative period in school-age children undergoing lower…
- Trial name
- NCT01858402
- Testing
- Paracetamol, Dipyrone
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Baskent University
Stress Urinary Incontinence, Surgical Incision
Use of a Dual-agent Local Analgesic (Bupivacaine-meloxicam) for Abdominal Incisions in Patients Undergoing Retropubic Mid-urethral Sling Surgery
This study will compare the use of a dual-agent local analgesic (bupivacaine-meloxicam) for abdominal incisions in patients undergoing retropubic mid-urethral sling surgery to see if narcotic usage and pain are impacted.
- Conditions
- Stress Urinary Incontinence, Surgical Incision, Pain Vulva
- Trial name
- NCT05702827
- Testing
- Bupivacaine-Meloxicam
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- TriHealth Inc.
Postoperative Pain, Acute
Combined Ketorolac Bupivacaine Versus Bupivacaine Alone for TAP Block in Children Undergoing Lower Abdominal Surgeries
Control of of pain in children is fundamental. TAP block is associated with less side effects compared with other neuraxial techniques especially when done under ultrasound guidance.
- Trial name
- NCT06267820
- Testing
- Bupivacain, Ketorolac
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Sohag University
Anesthesia, Recovery Period
TAPB vs. Caudal for Lower Abdominal Surgery in Children: A Double-Blinded Randomized Controlled Trial
Transversus abdominis plane block (TAPB) has emerged as a safe and effective regional anesthesia technique for providing postoperative lower abdominal analgesia.
- Trial name
- NCT02160821
- Testing
- Caudal Epidural, Transversus Abdominis Plane Block
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Nemours Children's Clinic
Post-Dural Puncture Headache
Trans-nasal Sphenopalatine Ganglion Block Versus Ultrasound-guided Bilateral Greater and Lesser Occipital Nerve Block for Management of Post-Dural Puncture Headache.
Post-Dural Puncture Headache (PDPH) is a complication associated with spinal anesthesia. While conventional treatments are available, the Epidural Blood Patch (EBP) is considered the gold standard.
- Trial name
- TNSPGB /GALONB (NCT06705244)
- Testing
- Trans-nasal sphenopalatine nerve block, Greater and lesser occipital nerve block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Pain After Surgery
RISS Versus Lower Thoracic ESP Block for Analgesia After Laparoscopic Abdominal Surgery: A Randomized Trial
The goal of this clinical trial is to investigate the analgesic efficacy of ultrasound-guided Romboid Intercostal and Subserratus (RISS) block versus lower thoracic Erector Spinae Plane (ESP) block after laparoscopic abdominal…
- Trial name
- NCT07593300
- Testing
- Group A (n=35): Ultrasound-guided RISS block (RISS):, Group B (n=35): Ultrasound-guided lower thoracic ESP block
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Post-operative Pain
Dexmedetomidine Added to Bupivacaine for ESP Block in Children Undergoing Lower Abdominal Surgeries
This study aims to evaluate the effect of adding dexmedetomidine to bupivacaine in erector spinae plane (ESP) blocks on the duration of postoperative analgesia in pediatric patients undergoing lower abdominal surgery.
- Trial name
- NCT07023991
- Testing
- Bupivacaine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain
EXPAREL Administered by Infiltration Into the TAP for Prolonged Postsurgical Analgesia in Lower Abdominal Surgeries
The purpose of this prospective, blinded assessor, randomized trial is to assess opioid use and patient-reported outcomes of EXPAREL as a foundation in postsurgical pain therapy in Transversus Abdominis Plane (TAP) infiltration…
- Trial name
- TRANSCEND (NCT01919190)
- Testing
- EXPAREL
- Where
- 13 sites in United States
- Volunteers
- 67 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Postoperative Pain
Erector Spinae vs TAP in Lower Abdominal Surgery
The aim of this study is to compare the analgesic effect and safety profile of erector spinae plane block with transverses abdominis plane block in controlling peri-operative pain for lower abdominal cancer surgery.
- Trial name
- NCT04555993
- Testing
- lower abdominal surgery, Erector spinae plane block, Transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- National Cancer Institute, Egypt
Anesthesia
Dexmedetomine vs Dexamethasone in TAB Block for Abdominal Surgries
Randomized controlled clinical Trial to compare the efficacy and duration of postoperative analgesia achieved after adding dexmedetomidine or dexamethasone to bupivacaine in TAP block for lower open abdominal surgeries.
- Trial name
- NCT05323565
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Ain Shams University
Post Operative Pain
Two Doses of Dexmedetomidine as Adjuvent to Bupivacaine in Tap Block
The aim of this study to determine the optimal dose of dexmedetomidine as an adjuvant to bupivacaine in U.S guided TAP block for preemptive analgesia In patients undergoing lower abdominal cancer surgeries.
- Trial name
- Dexmed/tap (NCT06624319)
- Testing
- Dexmedetomidine as adjuvent to bupvacaine in tap block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Local Analgesia Via Infiltration, Caudal Epidural Anesthesia
Perioperative Analgesia Using Ultrasound Guided Erector Spinae Block vs Ultrasound Guided Caudal Block for Pain Control in Children Aged 2-7 Years Undergoing Lower Abdominal Surgery
The goal of this prospective study is to is to evaluate the perioperative pain management of Erector Spinae Block versus Caudal Block using the Face, Legs, Activity, Cry, Conceal ability (FLACC) Pain Scale inn children aged 2 to…
- Conditions
- Local Analgesia Via Infiltration, Caudal Epidural Anesthesia, Caudal Block, Caudal Block for Postoperative Analgesia
- Trial name
- NCT07281235
- Testing
- Ultrasound Guided Bilateral single shot Erector Spinae Plane Block, Caudal Block Anesthesia
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Postoperative Pain
Dexmedetomidine Versus Magnesium Sulfate Infusion During Spinal Anesthesia
The aim of this work is to compare the hemodynamic and analgesic properties of Dexmedetomidine and Magnesium sulphate infusion in lower abdominal surgery.
- Trial name
- NCT03640390
- Testing
- Dexmedetomidine, Magnesium Sulphate, Normal saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Pain, Postoperative
Magnesium Sulfate as an Adjuvant to Caudal Bupivacaine in Lower Abdominal Surgeries in Paediatrics.
Intravenous magnesium has been studied in pediatrics to reduce agitation after sevoflurane anesthesia in children undergoing adenotonsillectomy, reduce intraoperative rocuronium requirements, prevent laryngospasm and coughing…
- Trial name
- NCT03322878
- Testing
- Magnesium SO4
- Volunteers
- 90 people
- Sponsor
- Cairo University
Emergence Agitation, Postoperative Pain
Caudal Versus Intravenous Magnesium Sulfate on Emergence Agitation After Sevoflurane In Children.
Sevoflurane is the agent of choice for induction and maintenance of day care anesthesia in children and has a wide acceptance among pediatric anesthesiologists.
- Trial name
- NCT03846284
- Testing
- Bupivacaine, Magnesium sulfate 50mg, Magnesium sulfate 30 mg
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Mansoura University
Pain Relief to the Patient Following Abdominal Surgeries
Comparative Evaluation of Quadratus Lumborum and Transverses Abdominis Plane Block for Postoperative Pain Relief in Lower Abdominal Surgeries
Two ultrasound guided techniques to give postoperative pain relief to the patients following abdominal surgeries would be compared using scoring systems for pain relief and scientific methods.
- Trial name
- NCT02910947
- Testing
- ultrasound guided quadratus lumborum or Transversus Abdominis plane block
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Postoperative Pain, Postoperative Nausea and Vomiting
Analgesic Effect of Preoperative Dexamethasone in Gynecological Laparotomies - a Dose-ranging Study
The objective of the study is to examine the effect of the addition of intravenous dexamethasone 1.5 hours prior to induction of anesthesia on the post-operative opioid consumption, pain scores, fatigue, and recovery in patients…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Fatigue
- Trial name
- NCT01022528
- Testing
- Dexamethasone (0.1 mg/kg), Dexamethasone (0.2 mg/kg), Saline
- Where
- Canada
- Volunteers
- 138 people
- Sponsor
- Women's College Hospital
Postoperative Pain
intrathecaم Ketamine, Morphine and Both for Lower Abdominal Cancer Surgery Pain
this study investigates the analgesic efficacy and other possible effects of ketamine, morphine, and both together when administered intrathecally for control of postoperative pain following lower abdominal cancer surgeries.
- Trial name
- NCT02726828
- Testing
- intrathecal morphine, intrathecal ketamine, intrathecal morphine + ketamine
- Volunteers
- 90 people
- Sponsor
- Assiut University
Pain
Postoperative Analgesic Effects of Dexmedetomidine for Transversus Abdominis Plane Block
the aim of this study is evaluate postoperative analgesic effects of dexmedetomidine added to bupivacaine on TAP block in patients undergoing lower abdominal surgery.
- Trial name
- TAP (NCT02064530)
- Testing
- Bupivacaine, Dexmedetomidine, serum physiologic
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- TC Erciyes University