Clinical trials: Lower Back Pain
Sciatica, Low Back Pain
Physiotherapy for Sciatica; Is Earlier Better?
This study aims to evaluate the whether receiving physiotherapy early after onset of the problem is better than waiting a few weeks to see if it gets better before starting physiotherapy.
- Conditions
- Sciatica, Low Back Pain, Radiculopathy
- Trial name
- POLAR (NCT02618278)
- Testing
- Physiotherapy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Michael Reddington
Chronic Pain
Neurophysiological Basis of Rehabilitation in Complex Regional Pain Syndrome, Type I and Chronic Low Back Pain
Complex Regional Pain syndrome Type I (CRPS-I) is a chronic progressive disease. Patients experience dramatic decline of overall well-being, despite the absence of any apparent physical cause.
- Trial name
- BrainEXPain (NCT02347579)
- Where
- Netherlands
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Chronic Pain
Can Therapy Alter CNS Processing of Chronic Pain: A Longitudinal Study
The purpose of this study is to investigate whether a psycho-therapeutic approach, group Cognitive Behavioral Therapy (CBT) plus a relapse prevention program, Therapeutic Interactive Voice Response (TIVR), modifies the…
- Trial name
- NCT01794988
- Testing
- Group Cognitive Behavioral Therapy, Pain Education, Therapeutic Interactive Voice Response
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Low Back Pain, Rehabilitation Program
Oxygenation of Paravertebral Muscles During Exercise in Chronic Low Back Pain Patients
The study evaluate paraspinal aerobic metabolism of chronic low back pain patients and healthy people during an original and standardized isokinetic protocol.
- Conditions
- Low Back Pain, Rehabilitation Program, Muscular Weakness
- Trial name
- OXYLOM (NCT03055182)
- Testing
- Physical rehabilitation program
- Where
- France
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Chronic Low Back Pain
Prevalence of Potential Cytochrome P450 Pharmacokinetic Incident Drug-Drug Interactions Among Chronic Low Back Pain Patients Taking Opioid Analgesics and Associated Economic Outcomes
This study explored the prevalence of DDEs in a chronic pain population with cLBP and associated healthcare utilization and costs using a healthcare claims database.
- Trial name
- NCT01177280
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- NEMA Research, Inc.
Low Back Pain, Core Stability
Lumbar School Training or Core Stabilization Exercises on Pain, Mobilization and Quality of Life Low Back Pain
Chronic low back pain (CLBP) is defined as low back pain lasting longer than three months. CLBP is one of the most common and expensive diseases in terms of both labour loss and treatment costs, and it is very important to treat…
- Conditions
- Low Back Pain, Core Stability, Core-based Exercise, Back School
- Trial name
- Lowbackpain (NCT06203340)
- Testing
- Core stabilizasyon and lumbal back school
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Chronic Low-back Pain
The Effect of Physiotherapy on Chronic Low Back Pain
Demographic data of patients diagnosed with chronic low back pain and planned for medical treatment (n:30) and physical therapy in addition to medical treatment (n:30), as well as before and after treatment; Visual analog scale…
- Trial name
- NCT06234891
- Testing
- Nsaid, Phsiotheraphy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Low Back Pain
Reformer Pilates vs Conventional Physiotherapy in Chronic Low Back Pain
Non-specific chronic low back pain is one of the most prevalent musculoskeletal disorders worldwide and is associated with functional limitations and reduced quality of life.
- Trial name
- NCT07543952
- Testing
- reformer Pilates exercises, conventional physiotherapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Low Back Pain
Worksite Exercise Interventions for Low Back Injury Prevention in Firefighters
Purpose and Aims: The purpose of this study is to assess the clinical effectiveness of back and core exercise interventions for low back injury prevention in firefighters. Aim 1.
- Trial name
- NCT02362243
- Testing
- Experimental Intervention
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Low Back Pain
The Effect of Exercise on Motion Perception and Fear in Low Back Pain
Nonspesific low back pain (NLBP), which negatively affects functionality, activity participation, and financial situation, is now one of the leading causes of disability in the world.
- Trial name
- NCT05433311
- Testing
- Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Low Back Pain, Recurrent, Healthy
Effects of Sleep Disruption on Drug Response
The central scientific premise of the proposed study is that sleep disruption (SD) will influence individuals' subjective response to blinded medication administration.
- Trial name
- NCT03680287
- Testing
- Within-Subject test of blinded study medication
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Oxygen Metabolism, Muscle Spasticity
Hemodynamic Changes During Dry Cupping Therapy on Low Back Pain
This study aims to investigate the hemodynamic changes during dry cupping therapy (DCT) on low back pain. 50 patients with low back pain as experimental group and 50 healthy people as control group are treated by DCT.
- Trial name
- NCT03816787
- Testing
- Negative pressure therapy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Chronic Low-back Pain, Facet Joint Pain
Cryoneurolysis Outcome on Pain Experience (COPE) in Patients With Low-back Pain
This study will provide information on the effectiveness of cryoneurolysis for patients with facet joint pain syndrome, and help to establish whether cryoneurolysis should be implemented in clinical practice for this patient…
- Conditions
- Chronic Low-back Pain, Facet Joint Pain, Degeneration Lumbar Spine, Facet Joint Syndrome
- Trial name
- COPE (NCT04786145)
- Testing
- Cryoneurolysis, Radiofrequency ablation
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Low Back Pain, Guideline Adherence
Understanding How Physiotherapists in Türkiye Follow Low Back Pain Guidelines and What Affects Their Use of Research in Practice
The goal of this observational study is to understand how physiotherapists and physiotherapy students in Türkiye manage low back pain and how closely they follow clinical practice guidelines and use research evidence.
- Conditions
- Low Back Pain, Guideline Adherence, Physiotherapist, Physiotherapist Students
- Trial name
- NCT07178548
- Testing
- Online Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Medipol University
Low Back Pain, Mechanical
Dry Needling to the Multifidus Muscle in Subjects With Low Back Pain
To examine for differences in contraction thickness of the transversus abdominis muscle in symptomatic subjects with mechanical lower back pain following the application of dry needling to the lumbar multifidus muscles.
- Trial name
- NCT02284724
- Testing
- Dry Needling
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Chronic Pain, Lower Back Pain Chronic
Lumbar Injectrode Feasibility Evaluation
The goal of this non-significant risk study is to determine whether stimulation with transcutaneous waveforms applied on the outside of the body and subcutaneously conducted to the lumbar medial branch nerve elicits visible (via…
- Trial name
- LIFE (NCT06206356)
- Testing
- PNS Injectrode F1
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Neuronoff, Inc
Low Back Pain, Mechanical
Battlefield Acupuncture for Acute/Subacute Back Pain in the Emergency Department
The randomized controlled study aims was to investigate the pain control of Battle Field Acupuncture as Primary or Adjunctive Treatment in Back Pain (Acute Musculoskeletal pain) in the (acute pain setting) Emergency Department vs…
- Trial name
- NCT03996564
- Testing
- Battlefield Acupuncture, Acetaminophen, Diclofenac
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- San Antonio Military Medical Center
Low Back Pain
Pain Resilience and Spiritual Health in Low Back Pain
In the management of chronic pain, it is very important to reaffirm the patient's self-worth and ability through psychological support and spiritual care.
- Trial name
- NCT05148364
- Testing
- interview
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Changhua Christian Hospital
Chronic Low Back Pain
Tolerability, Safety and Pharmacokinetics of a Topical AB001 Patch in Healthy Subjects
The study evaluates the safety, tolerability and pharmacokinetics of single and repeated doses of topical AB001 patch and the bioavailability relative to the oral capsule and topical positive comparative patch.
- Trial name
- NCT03997734
- Testing
- AB001, oral capsule, positive comparative patch
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Frontier Biotechnologies Inc.
Chronic Low-back Pain, Healthy
Detection of EEG-Based Biomarkers of Chronic Low Back Pain
Chronic low back pain (CLBP) is a pervasive disorder affecting up to one-fifth of adults globally and is the single greatest cause of disability worldwide.
- Trial name
- NCT06025201
- Testing
- Resting State EEG, Picture Viewing EEG, Stop Signal EEG
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Stanford University