Clinical trials: Lower Back Pain Chronic
Back Pain Lower Back Chronic
Evaluation of the Short-term Effectiveness of Spinal Manipulation to Treat Acute and Subacute Low Back Pain.
Low back pain is the second most common reason for medical consultation in France and affects 60 to 80% of the working population.
- Trial name
- MeLoPe (NCT07403500)
- Testing
- Spinal or peripheral manipulation of the lower back to treat lower back pain
- Where
- France
- Volunteers
- 416 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Back Pain, Back Pain Lower Back
Use of Ultrasound Imaging in Confirming Osteopathic Spinal Diagnosis
In the field of Osteopathic Medicine, diagnosis of potential areas of dysfunction are diagnosed by the physician using their hands and expertise in noticing subtle differences in symmetry, tone, swelling etc..
- Conditions
- Back Pain, Back Pain Lower Back, Back Pain Lower Back Chronic, Back Pain With Radiation
- Trial name
- NCT07858071
- Testing
- Spinal Ultrasound
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- The Touro College and University System
Chronic Lower Back Pain (CLBP)
Mechanistic Evaluation of Polypharmacy Effects for Pain
This is a single-group, within-subject, double-blind, double-dummy, placebo-controlled study evaluating whether gabapentin (Neurontin) changes the analgesic, safety, and subjective effects of the opioid hydromorphone (Dilaudid)…
- Trial name
- PAT (NCT07846020)
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Maryland, Baltimore
Back Pain Lower Back Chronic, Spinal Cord Stimulation
EVOKE ECAP-Controlled Lead Placement and Programming in Chronic Pain Patients
This study is designed to evaluate the feasibility of using intra-operative ECAP and Late-Response (LR) recordings for confirmation of activating the neuronal target of the dorsal column in a single-stage SCS lead placement…
- Trial name
- ECAP (NCT05704751)
- Testing
- spinal cord stimulation
- Where
- United Kingdom
- Sponsor
- Barts & The London NHS Trust
Low Back Pain, Back Pain Lower Back Chronic
The Forgotten Role of Back Muscle Characteristics to Tailor Exercise Therapy for Recurrent Non-specific Low Back Pain
Patients with non-specific low back pain will be compared to healthy, age- and sex-matched controls to determine the most discriminating back muscle characteristics and to delineate possible phenotypes of patients with…
- Trial name
- Back-to-Back (NCT05851196)
- Testing
- Proprioceptive training
- Where
- 2 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Low Back Pain, Chronic Low-back Pain
YOga for Patients With Chronic BACK Pain and Poor PROgnosis
The goal of this clinical trial is to investigate the effectiveness of yoga for patients with chronic low back pain and high risk of poor prognosis.
- Conditions
- Low Back Pain, Chronic Low-back Pain, Back Pain, Back Pain Lower Back Chronic
- Trial name
- YOBACK-PRO (NCT05953155)
- Testing
- Control, Yoga
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Federal University of Minas Gerais
Back Pain Lower Back Chronic
A Comparative Study of Erector Spinae Fascia (ESF) Injection and Dry Needling Combined With Functional Rehabilitation (FR) in Patients With Chronic Low Back Pain Who Have Undergone Spinal Surgery (SPIN-NEED)
Chronic low back pain represents a major public health issue, with an estimated prevalence of up to 23% in the adult population and a significant impact on quality of life and functional capacity.
- Trial name
- SPIN-NEED (NCT07555496)
- Testing
- infiltration of the erector spinae fascia, Dry needling
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Clinique de la Côte d'Emeraude
Chronic Lower Back Pain (CLBP)
Brief Pain Reprocessing Therapy in Veterans
This research is studying whether a Zoom-based behavioral intervention may have an impact as a treatment for Veterans with Chronic Low Back Pain (CLBP).
- Trial name
- NCT06771713
- Testing
- Brief Pain Reprocessing Therapy (BPRT)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Chronic Lower Back Pain
Assessment of Usability and Satisfaction With a Take-home Device Presenting Sound and Body Stimulation for Back Pain
Pain symptoms can have a variety of ways to be treated, from medications to physical therapy, with several options being available to patients.
- Trial name
- NCT06619418
- Testing
- TENS device, Integrative health modalities
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Chronic Pain, Chronic Back Pain
Virtual Reality Treatment for Adults With Chronic Back Pain (VRNT)
Participants with chronic back pain will complete an online Qualtrics eligibility survey. After signing a consent form, eligible participants enter a two-week baseline period ("Baseline Period"), during which they complete two…
- Conditions
- Chronic Pain, Chronic Back Pain, Chronic Lower Back Pain (CLBP)
- Trial name
- NCT07033195
- Testing
- Skills-based Virtual Reality Therapy, Distraction-based Virtual Reality Therapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- CognifiSense Inc.
Substance Use Disorders, Chronic Pain
IMPOWR-ME Project 1: Trial of Yoga and Physical Therapy Onsite at Opioid Treatment Programs
This is a pragmatic, open label, randomized controlled trial with 1:1:1 allocation to 12 weeks of: (1) onsite yoga at opioid treatment programs (OTPs), (2) onsite physical therapy (PT) at OTPs, or (3) treatment as usual (TAU).
- Conditions
- Substance Use Disorders, Chronic Pain, Opioid Use Disorder, Back Pain Lower Back Chronic
- Trial name
- NCT05492825
- Testing
- Yoga, Physical Therapy, Treatment As Usual
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Albert Einstein College of Medicine
Lower Back Pain, Obesity (BMI>30)
Semaglutide for Low Back Pain
Low back pain is the leading cause of disability in the United States, and obesity is a major risk factor for its development. GLP-1 receptor agonists such as Semaglutide have emerged as effective weight loss agents that may also…
- Conditions
- Lower Back Pain, Obesity (BMI>30), Chronic Lower Back Pain, glp1 Agonist
- Trial name
- NCT07731256
- Testing
- Semaglutide (administered by PDS290 pen-injector)
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Washington University School of Medicine
Persistent Spinal Pain Syndrome Type 2 (PSPS-T) Lower Spine, Chronic Low Back Pain
SPINE-RISK VE: Multimodal Predictive Model for Failed Back Surgery Syndrome in Venezuelan Surgical Patients
SPINE-RISK VE is a prospective multicenter cohort study designed to develop and internally validate a multimodal preoperative predictive model for Failed Back Surgery Syndrome (FBSS), now classified as Persistent Spinal Pain…
- Conditions
- Persistent Spinal Pain Syndrome Type 2 (PSPS-T) Lower Spine, Chronic Low Back Pain, Postoperative Pain, Lumbar Spine Surgery
- Trial name
- SPINE-RISK VE (NCT07693517)
- Testing
- SPINE-RISK VE multimodal preoperative assessment
- Where
- Venezuela
- Volunteers
- 150 people
- Sponsor
- juan jose valero quintero,MD
Chronic Lower Back Pain (CLBP), Lumbar Facet Joint Pain
Lumbar Facet Platelet-Rich Plasma Injection Versus Medial Branch Radiofrequency Ablation for Chronic Lumbar Facet-Mediated Pain
The first clinical research effort under this initiative is a pilot randomized controlled trial comparing intra-periarticular lumbar facet platelet-rich plasma (PRP) injection to standard-of-care medial branch radiofrequency…
- Trial name
- NCT07692737
- Testing
- Platelet Rich Plasma Joint Injection, Medial branch radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- The New England Baptist Hospital
Lower Back Pain
Improving Access to Chiropractic Care in Community Health Centers
The goal of this study is to evaluate the feasibility of new implementation strategies designed to increase the number of Primary Care Providers (PCPs) referrals to chiropractic care for lower back pain (LBP) in underserved…
- Trial name
- NCT06104605
- Testing
- Institutional interventions, PCPs interventions, Patient interventions
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Boston Medical Center
Chronic Mechanical Lower Back Pain, Lower Back Pain
Adia Med of Winter Park LLC Lower Back Pain Research Study
The goal of this clinical study is to evaluate the safety and preliminary efficacy of an investigational umbilical cord blood-derived stem cell and exosome infusion in adults with chronic lower back pain associated with…
- Conditions
- Chronic Mechanical Lower Back Pain, Lower Back Pain, Chronic Lower Back Pain
- Trial name
- NCT07587047
- Testing
- Umbilical Cord Blood-Derived Stem Cells and Exosomes
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Adia Med of Winter Park LLC
Lower Back Pain Chronic
Trial to Test the Efficacy of Using Magnetic Fields to Stimulate the Back to Treat Chronic Lower Back Pain.
The goal of this study is to see if a new way to treat back pain without the use of medications is effective. We plan use Transcranial Magnetic Stimulation (TMS), a wand-like device, to excite the nerves of people with lower back…
- Trial name
- NCT07652944
- Testing
- peripheral magnetic stimulation, Home exercise
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Joe X. Zhang
Lower Back Pain Chronic
The Potential of Transcutaneous Electrical Nerve Stimulation to Improve Pain Experienced During Posterior Branch Blocks in Patients With Lumbar Posterior Joint Syndrome
Procedural pain is inadequately managed in two-thirds of patients undergoing invasive medical procedures. Several techniques exist for managing procedural pain, but they all present implementation challenges and are not without…
- Trial name
- TENS-INFIDOL (NCT07627490)
- Testing
- Stimulation with TENS, which allows the release of endorphins, Stimulation with TENS does not allow the release of endorphins, Questionnaires
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Toulouse
Sciatica, Lumbar Radiculopathy
Brain Mechanisms Supporting Cannabis-induced Pain Relief
Chronic low back pain is a common and disabling condition that affects millions of people in the United States. Many people with chronic low back pain do not get enough relief from current treatments.
- Conditions
- Sciatica, Lumbar Radiculopathy, Lower Back Pain, Degenerative Disc Disease
- Trial name
- NCT04982965
- Testing
- Active Cannabis
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Low Back Pain, Chronic Pain
Non-pharmacological Treatment for Pain After Spine Surgery
This study will compare the effectiveness of two pain management pathways (standard vs. enriched) for patients undergoing lumbar spine surgery in the Military Health System (MHS).
- Conditions
- Low Back Pain, Chronic Pain, Surgery, Back Pain, Low
- Trial name
- NCT04770480
- Testing
- Standard Care (SC), Enriched Pain Management Pathway (EPM)
- Where
- 3 sites in United States
- Volunteers
- 267 people
- Sponsor
- Dan Rhon