Clinical trials: Lower Extremity Function
Ankle Sprain
Effect of Joint Mobilization in the Treatment of Chronic Ankle Instability
The purpose of this study is to examine the effects of a gentle pressure movement performed at the ankle by a physical therapist on muscle function and ankle motion in individuals who frequently twist (sprain) their ankle.
- Trial name
- NCT01438905
- Testing
- Small amplitude (Grade IV) mobilization, High velocity, low amplitude (Grade V) mobilization
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Creighton University
Unilateral Lower Limb Suspension (Simulated Microgravity)
Unloaded Minds - How Prolonged Unloading Shapes Human Performance in Lunar Gravity
During spaceflight and lunar missions, reduced gravitational loading causes the muscles and nervous system to decondition rapidly.
- Trial name
- UnloadedMinds (NCT07607340)
- Testing
- Unilateral lower limb suspension
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Patella, Joint Instability
Development of a Test Battery for Measurement of Knee Function in Patients With Patellar Instability
About six months after patella stabilizing surgery postoperative restrictions are commonly lifted and patients may consider whether a return to activity/sports is feasible.
- Conditions
- Patella, Joint Instability, Patellofemoral Joint Dislocation
- Trial name
- NCT05119088
- Testing
- Return to Sport testbattery
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Haraldsplass Deaconess Hospital
Fatigue, Muscle Injury
Immediate and Short-term Effects of Low-level Laser
Athletes experience an exhaustive routine of training, associated with the reduced time of rest, facilitates the appearance of muscle fatigue, which increases the risk of muscle injuries, especially during the execution of the…
- Trial name
- NCT05344183
- Testing
- Low-level laser
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Amapá
Neuromuscular Electrical Stimulation
Effects of Lower Extremity Functional Exercise Program and Neuromuscular Electrical Nerve Stimulation in Older Adults
The aim of this study was to investigate and compare the effects of lower extremity functional exercise program and neuromuscular electrical nerve stimulation on muscle thickness, muscle strength, gait and fall risk in the…
- Trial name
- NCT07076797
- Testing
- EXERCISE TRAINING, NMES
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Biruni University
ACL Reconstruction, Cognitive Function
Test of Return to Sport After ACL Reconstruction and Cognitive Task.
After reconstruction of the anterior cruciate ligament, the aim for the vast majority of sportspeople is to return to the field.
- Conditions
- ACL Reconstruction, Cognitive Function, Single Leg Hop Firm Surface, Testing Effect of Intervention
- Trial name
- AQQSHTATC (NCT06768957)
- Testing
- Single leg hop for distance, Single leg hop for distance plus cognitive task
- Where
- 4 sites in France
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Simon VALOT
Pain in Leg, Unspecified, Knee Sprain
Efficacy of Instrumental Chiropractic Treatment Using Activator Methods for Pain and Dysfunction in Juvenile Athletes
The goal of the study is to prove efficacy of instrumental chiropractic treatment for leg pain in juvenile athletes. A randomized placebo controlled clinical trial including juvenile athletes with functional impairment and pain…
- Trial name
- NCT01449994
- Testing
- Activator IV (Activator Methods Int. Phoenix, Arizona)
- Where
- Austria
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Aging, Athletic Injuries
Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health
Competitive sport increases risk for musculoskeletal injury (e.g., traumatic knee injury) and may position former athletes for early onset of chronic diseases, chronic pain, poor health-related quality of life, and disability.
- Conditions
- Aging, Athletic Injuries, Physical Inactivity, Knee Injuries and Disorders
- Trial name
- NCT05344001
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Marquette University
Obesity, Adolescent
Comparison of the Effects of Two Different Exercise Programs in Obese Adolescents
Obesity is one of the most important health problems of developed and developing countries. Especially in children and adolescents, the prevalence of obesity is increasing at an alarming rate.
- Trial name
- NCT04491019
- Testing
- Balance exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Lipedema, Hypermobility Syndrome (Disorder)
Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema
Lipedema is a chronic adipose tissue disorder that commonly leads to joint laxity, hypermobility, and functional limitations, yet its impact on foot morphology has not been systematically examined.
- Conditions
- Lipedema, Hypermobility Syndrome (Disorder), Pes Planus, Joint Hypermobility
- Trial name
- NCT07294014
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Marmara University
Movement, Abnormal, Lower Extremity Problem
Hip Activation vs. Hip Activation + Core Stabilization
The purpose of this investigation is to compare the effects of a combined hip activation and core stabilization training home exercise program (HEP) versus a hip activation training HEP alone on lower extremity (LE) frontal plane…
- Trial name
- NCT06260306
- Testing
- Hip activation home exercise program, Hip activation plus core stabilization home exercise program
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Distal Femoral Musculoskeletal Tumors
Functional Outcomes and Quality of Life in Musculoskeletal Tumor Patients With Distal Femoral Megaprostheses
This study aims to evaluate the functional outcomes of patients with distal femur tumor prostheses in comparison to a matched control group.
- Trial name
- FOQ-DFP (NCT06282198)
- Where
- Spain
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Recurrent Patella Dislocation
MPFL vs Campbell in Recurrent Patella Dislocation
This study will compare anatomic Medial Patellofemoral Reconstruction from Hamstring graft with non anatomic reconstruction according to Campbell.
- Trial name
- NCT05488275
- Testing
- Surgery
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre of Postgraduate Medical Education
Healthy
Impact of Foot Mobility Techniques on Balance and Pressure in Young Adults
This study aims to evaluate the effectiveness of specific foot mobility techniques on functional and biomechanical parameters of the foot in young adults aged 18 to 24 years.
- Trial name
- NCT06817798
- Testing
- Specific foot mobility
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cooperativa de Ensino Superior, Politécnico e Universitário
Sports Physical Therapy, Physical Functional Performance
Outdoor Horseback Riding and Its Effects on Muscle Strength, Balance, Sleep, and Movement
This study aims to investigate the effects of regular outdoor horseback riding on lower extremity muscle strength, core stabilization, balance, functional movement capacity, sleep quality, and overall well-being in healthy…
- Conditions
- Sports Physical Therapy, Physical Functional Performance, Horseback Riding
- Trial name
- NCT07286864
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Istinye University
Knee Osteoarthritis
Comparison of Functional Outcomes of Three Surgical Approaches in Knee Arthroplasty
A functional outcomes comparison study of three surgical techniques using minimally invasive surgery mini-incision (MIS) for total knee arthroplasty (TKA), standard para-patellar TKA and the unicompartmental knee arthroplasty…
- Trial name
- NCT00983762
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Sports Physical Therapy
Comparative Effects of Heavy Slow Resistance Training and Eccentric Overload Training in Runners
Patellar Tendinopathy (PT) also known as Jumper's knee, is characterized by multifaceted activity-related pathology causing anterior knee pain and patellar-tendon dysfunction.
- Trial name
- NCT06877741
- Testing
- Group A (Heavy Slow Resistance exercises), : Group B (Eccentric exercises)
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Disuse Atrophy (Muscle) of Lower Extremities, Muscle Function
The Impact of Bed Rest, Aging and NMES on Skeletal Muscle
Loss of muscle mass is common phenotypic trait of muscular disuse and ageing. The loss of muscle mass affects, among others, the ability to maintain homeostasis of glucose metabolism and the energy reservoir in catabolic…
- Conditions
- Disuse Atrophy (Muscle) of Lower Extremities, Muscle Function, Neuromuscular Electrical Stimulation, Myofibrillar Protein Synthesis
- Trial name
- NCT05617222
- Testing
- Bed rest, Neuromuscular electrical stimulation
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Child Development, Upper Motor Neurone Lesion
Validity and Reliability of the PROprioception Measurement Tool (PROMT)
This project assesses the feasibility, reliability, and validity of the PROMT in children with a UMN lesion. The study questions are: is the newly developed PROMT a feasible, reliable, and valid tool to assess lower limb…
- Conditions
- Child Development, Upper Motor Neurone Lesion, Cerebral Palsy, Proprioceptive Disorders
- Trial name
- PROMT (NCT05405881)
- Testing
- Proprioception measurement tool
- Where
- Switzerland
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Mobility Limitation
Lower Extremity Muscle and Function in the Elderly: Study 2
This research study is looking to compare the effects of two uniquely different power training interventions (high force, lower velocity versus low force, high velocity) on changes in mobility status among older individuals at…
- Trial name
- NCT01614392
- Testing
- High velocity low force Power Training, Low velocity high force Power Training
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tufts University