Clinical trials: Lower Extremity Function
Atherosclerosis, Stable Angina
Remote Ischemic Preconditioning as a Method Against Subclinical Renal Injury and Contrast-induced Nephropathy
Contrast-induced nephropathy (CIN) has remained significant and severe complication of angiographic procedures despite the increasing use of preventative methods.
- Conditions
- Atherosclerosis, Stable Angina, Peripheral Artery Disease, Contrast-induced Nephropathy
- Trial name
- NCT02700958
- Testing
- Remote ischemic preconditioning
- Where
- Estonia
- Volunteers
- 160 people
- Sponsor
- Tartu University Hospital
Spinal Cord Injury
Transcutaneous Electrical Spinal Cord Stimulation for Lower Limbs
This study is to determine if non-invasive electrical stimulation of the spinal cord can be used to: 1) assess spared function following a spinal cord injury; and 2) be use for rehabilitation.
- Trial name
- NCT01949285
- Testing
- Transcutaneous Electrical Spinal Cord Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- NeuroEnabling Technologies, Inc.
ACL - Anterior Cruciate Ligament Rupture
Description of Return to Sport in Amateur Athletes Who Underwent Several Functional Tests (K-STARTS, Vertical Jumps and Soleus Muscle Strength) After Initial ACL Reconstruction
ACL injuries are incapacitating for both professional and amateur athletes, with long-term repercussions on performance and return to sport (RTS). Surgical reconstruction of the ACL is the main treatment option.
- Trial name
- K-STARTS + (NCT07249645)
- Testing
- Physical tests
- Volunteers
- 230 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Lower Extremity Biomechanics, Gastrocnemius Tightness
The Effect of Physiotherapy on Lower Extremity Function and Gait in Children with Isolated Gastrocnemius Muscle Tightness
Since the gastrocnemius muscle crosses both joints, the joint kinematics of the ankle are affected by knee flexion. According to the Kendall \& McCreary assessment of normal joint motion angles, the generally accepted normal…
- Conditions
- Lower Extremity Biomechanics, Gastrocnemius Tightness, Pes Planovalgus
- Trial name
- NCT06678139
- Testing
- physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bezmialem Vakif University
Mobility Limitation
Lower Extremity Muscle and Function in the Elderly: Study 2
This research study is looking to compare the effects of two uniquely different power training interventions (high force, lower velocity versus low force, high velocity) on changes in mobility status among older individuals at…
- Trial name
- NCT01614392
- Testing
- High velocity low force Power Training, Low velocity high force Power Training
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tufts University
Chronic Stroke, Sensory Impairments
Plantar Sensation, Position Sense, and Weight-Bearing Asymmetry Related to Balance and Mobility Post-Stroke
This study aims to examine how sensory deficits and weight-bearing asymmetry affect posture, balance, and mobility in individuals with chronic stroke.
- Conditions
- Chronic Stroke, Sensory Impairments, Postural Control, Balance
- Trial name
- NCT07065292
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Afyonkarahisar Health Sciences University
Healthy
Combining Resting Blood Flow Restriction with Neuromuscular Electrical Stimulation: Effects on Blood Lactate Levels and Lower Limb Muscle Function
The current research landscape shows studies indicating increased muscle strength and hypertrophy through neuromuscular electrical stimulation combined with blood flow restriction.
- Trial name
- NCT06196099
- Testing
- Blood Flow Restriction, Neuromuscular Electrical Stimulation, Squat exercise
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hyunjoong Kim
Spinal Cord Injuries
Lower Extremity Outcome Measures in SCI
Lower extremity (LE) function of patients with a spinal cord injury (SCI) will be assessed in an observational project with a cross-sectional and a longitudinal study design.
- Trial name
- NCT04032314
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hip Fracture, Post Surgery Recovery, Muscle Resilience
Hip Fracture and Muscle Resilience
The aging of the population is a major public health problem, particularly with regard to the quality of life and the maintenance of autonomy.
- Trial name
- HIPRESM (NCT04167020)
- Testing
- High definition surface electromyography (HD-sEMG)
- Where
- 4 sites in France
- Volunteers
- 67 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Physical Activity, Exercise
Comparison of the Effects of Two Different Exercise Programs in Office Workers
The aim of our study is to compare the effects of functional exercises and posture exercises on lower extremity functions, posture and physical activity in office workers.
- Conditions
- Physical Activity, Exercise, Office Worker, Lower Extremity Function
- Trial name
- NCT04726462
- Testing
- Functional exercises, Posture exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Aging
Effect of Ankle Splinting on Vascular Function in Aging
Endothelial function of the skeletal muscle vasculature declines with advancing age. Although aerobic exercise training is commonly prescribed to combat loss of endothelial function in the elderly, the rate of compliance to…
- Trial name
- NCT02144896
- Testing
- Ankle splinting
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Florida
Brain Injuries, Brain Injuries, Traumatic
Visual Feedback in Lower Limb Rehabilitation
Severe Acquired Brain Injury (sABI) is defined as "an encephalic impairment that occurs after birth and is not related to a congenital or degenerative disease.
- Conditions
- Brain Injuries, Brain Injuries, Traumatic, Brain Injuries, Vascular
- Trial name
- NCT05179330
- Testing
- OMEGO®
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Diplegic Cerebral Palsy With Spasticity, Cerebral Palsy, Spastic, Diplegic
Impact of rTMS Combined With Neurorehabilitation on Lower Extremity Motor Function and Spasticity in Children With Spastic Diplegic Cerebral Palsy
Cerebral palsy (CP) is widely recognized as the most prevalent cause of lifelong physical disability emerging in childhood across most global populations.
- Conditions
- Diplegic Cerebral Palsy With Spasticity, Cerebral Palsy, Spastic, Diplegic, Transcranial Magnetic Stimilation, Cerebral Palsy (CP)
- Trial name
- NCT07488429
- Testing
- TMS
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ankara City Hospital Bilkent
Asthma
Effects of Inhaled Ciclesonide Versus Fluticasone Propionate Versus Placebo on Lower Leg Growth in Prepubertal Children With Mild Persistent Asthma (6 to 12 y) (BY9010/M1-208)
The aim of the study is to compare the effects of ciclesonide inhaled at one dose level twice daily versus fluticasone propionate inhaled at one dose level twice daily versus placebo, on short-term lower leg growth in prepubertal…
- Trial name
- NCT00163371
- Testing
- Ciclesonide
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- AstraZeneca
Spinal Cord Stimulation
New Markers to Assess the Efficacity of Spinal Cord Stimulation for the Treatment of Chronic Lower Limb Pain (MOTIVE)
By combining the usual care of patients eligible for spinal cord stimulation (SME) with measurements of the HRV index (Heart Rate Variability), objective measurements of activity (number of steps, quality of sleep) and…
- Trial name
- NCT04785001
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Malleolus Fracture, Lateral
Comparing Function, Pain and Return to Work in Conservative Versus Surgical Treated Stable Lateral Malleolar Fractures
Ankle fractures are one of the most common fractures in adults resulting in hospital stays and inability to work. Instable or dislocated ankle fractures are mostly treated by surgery.
- Trial name
- NCT03587571
- Testing
- Surgical intervention
- Where
- Switzerland
- Volunteers
- 3 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Knee Injuries
Clinical Trial Comparing Three Anterior Cruciate Ligament Reconstructive Procedures
The objective of this prospective study is to assess the clinical, functional and radiological outcomes of three different ACL reconstruction procedures: Bone Patella Bone graft, Single bundle hamstring graft and anatomical…
- Trial name
- NCT00418964
- Testing
- Single bundle hamstring, Double bundle hamstring, Bone patellar tendon bone
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Chinese University of Hong Kong
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Comparative Evaluation of Functional Results and Survival Rate of Peroneus Longus Tendon - PLT and Hamstring Tendon - HT Used for Reconstruction of the Anterior Cruciate Ligament.
Comparative evaluation of functional results and survival rate of peroneus longus tendon - PLT and hamstring tendon - HT used for reconstruction of the anterior cruciate ligament.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Knee Injuries
- Trial name
- NCT05579067
- Testing
- ACL Reconstruction using an autograph of the peroneus longus tendon, folded twice., ACL Reconstruction using an autograph of Hamstrings muscle tendons.
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- eMKa MED Medical Center
Anterior Cruciate Ligament Injuries
Comparative Study of Functional Outcomes Between Peroneus Longus and Hamstring Tendon Autografts in Arthroscopic ACL Reconstruction
This is a prospective, single-blinded, randomized controlled trial. Sixty patients (≥18 years) with an isolated ACL injury will be randomly assigned to receive an ACL reconstruction using either a Peroneus Longus Tendon (PLT)…
- Trial name
- NCT07346326
- Testing
- Hamstring Tendon Autograft Harvest and ACL Reconstruction, Peroneus Longus Tendon Autograft Harvest and ACL Reconstruction
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Khyber Medical University Peshawar
Knee Injuries, Sport Injury, Knee Injuries
Effects of Mulligan Mobilization With Movement Versus Kinesiotaping and Placebo on Knee Function and Injury -Related Outcomes in Basketball Players
This is a randomized RTC study where the KOS-ADLS score of athletes' functionality and the OSTRC score of sports overuse injuries were used as outcomes, which were measured before the start of treatment, 1 hour and 2 weeks after…
- Trial name
- Sport _MWM_RTC (NCT07510243)
- Testing
- Mulligan Mobilization with movement MWM, Kinesiotaping
- Where
- Albania
- Volunteers
- 60 people
- Sponsor
- University Aleksander Moisiu Durres