Clinical trials: Lower Extremity Function
Anterior Cruciate Ligament Injury
Conditioning Brain Responses to Improve Thigh Muscle Function After Anterior Cruciate Ligament Reconstruction
The purpose of this study is to examine if thigh muscle weakness and the lack of muscle activation that accompanies ACL injury can be improved through a form of mental coaching and encouragement, known as operant conditioning.
- Trial name
- NCT03209531
- Testing
- Operant Conditioning, Control, Single Pulse Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Michigan
Diabetic Neuropathies, Peripheral Nervous System Diseases
Effect of Physical Therapy in Improving the Health of Patients With Diabetic Peripheral Neuropathy
People with diabetes can have nerve damage in their extremities (peripheral neuropathy), and this can lead them to being less able to maintain their balance when they are standing, walking or performing complex movement tasks in…
- Trial name
- DPN-QoL (NCT02115932)
- Testing
- Strength & Balance Training
- Where
- Singapore
- Volunteers
- 143 people
- Sponsor
- National University Health System, Singapore
Heart Failure
Neuromuscular Versus Resistance Training on Functional Capacity in Patients With Heart Failure.
This randomized controlled trial will compare the effects of neuromuscular training and resistance training on functional capacity, cardiorespiratory fitness, and lower limb performance in patients with chronic heart failure.
- Trial name
- NCT07519473
- Testing
- Resistance Training, Neuromuscular Training
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
ACL Injury, Muscle Weakness
Nordic Hamstring Exercise After ACL Reconstruction Reconstruction
Anterior cruciate ligament (ACL) injuries constitute a significant portion of major knee joint injuries sustained by young, active individuals, and significantly increase risk for long-term disability.
- Conditions
- ACL Injury, Muscle Weakness, Neuromuscular Manifestations
- Trial name
- NCT05738200
- Testing
- Nordic Hamstring Exercise
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Toledo
Asthma
Effects of Inhaled Ciclesonide Versus Fluticasone Propionate Versus Placebo on Lower Leg Growth in Prepubertal Children With Mild Persistent Asthma (6 to 12 y) (BY9010/M1-208)
The aim of the study is to compare the effects of ciclesonide inhaled at one dose level twice daily versus fluticasone propionate inhaled at one dose level twice daily versus placebo, on short-term lower leg growth in prepubertal…
- Trial name
- NCT00163371
- Testing
- Ciclesonide
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- AstraZeneca
Aged, Muscle Strength
Strengthening in Functional Mobility of Active Elderly
Aging is characterized by functional losses among which, the related to mobility and balance may be highlighted. Regular physical activity, including muscle strengthening exercises, is beneficial to a healthy elderly.
- Trial name
- NCT02968030
- Testing
- Muscle strength
- Where
- Brazil
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Lislei Jorge Patrizzi
Stroke, Spasticity, Muscle
Analysis of the Correlation Between Ultrasound Imaging and Functional Parameters in the Medial Gastrocnemius Muscle in Post-stroke Patients With Spasticity in the Lower Limb
The goal of this observational study is to understand the impact of spasticity on muscle changes and functional performance in stroke patients with lower limb spasticity in comparison to non-stroke individuals.
- Trial name
- US-function (NCT06411587)
- Testing
- Ultrasound imaging and functional assessment
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
ACL Injury
Functional Movement Training Versus Functional Stability Training in Post-ACL Surgery
This randomized controlled trial study will include 32 athletes aged 18-35 who had ACL surgery. After surgery, participants will be selected and assigned randomly to the Functional Movement Training or Functional Stability…
- Trial name
- NCT07725016
- Testing
- Functional Movement training, Functional stability training
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Cystic Fibrosis (CF)
Exercises' Effect on Muscle Strength, Aerobic Capacity and Respiratory Functions in Cystic Fibrosis
This research aims to evaluate the effects of upper and lower limb exercises on muscle strength and pulmonary function in children diagnosed with CF.
- Trial name
- NCT07508904
- Testing
- Arm Cycle Ergometry, Leg Cycle Ergometry
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Osteoarthritis of the Knee, Degenerative Osteoarthritis
Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee Osteoarthritis
The primary research purpose is to determine if the use of a drug therapy intervention (each study participant will be randomly assigned to receive one of 3 study medications which will be blinded from everyone, including the…
- Conditions
- Osteoarthritis of the Knee, Degenerative Osteoarthritis, Knee Pain Chronic
- Trial name
- PRPNSAIDsKOA (NCT05742763)
- Testing
- Ibuprofen and PRP, Acetaminophen and PRP
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- QC Kinetix LLC
Anterior Cruciate Ligament Injury
Psychological Readiness and Return to Sport After ACL Reconstruction
The goal of this observational study is to evaluate psychological readiness, kinesiophobia, subjective knee function, sport activity level, and return-to-sport status in athletes who have undergone primary anterior cruciate…
- Trial name
- NCT07733895
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Biruni University
Neuromodulatory Effects of TSCS and FES in Lower Limbs
Ultrasound for Quantifying Muscle Activation Elicited by Spinal Cord Stimulation and Functional Electrical Stimulation
Transcutaneous (non-invasive) spinal cord stimulation (tSCS) has been shown to facilitate volitional motor activity in patients with spinal cord injury.
- Trial name
- NCT07206797
- Testing
- Functional Electrical Stimulation, Transcutaneous (Non-Invasive) Spinal Cord Stimulation, Ultrasound
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Hip Fractures
Long vs Extended-short Nail When Treating Proximal Femur Fractures
Fractures of the upper part of the femur may be treated with intramedullary nails. There are different designs to choose from. The intention of this RCT is to compare two nails with some of the same properties, but with different…
- Trial name
- NCT04652310
- Testing
- TFNA extended-short nail (235 mm), TFNA long nail (260-480mm)
- Where
- 2 sites in Norway
- Volunteers
- 800 people
- Sponsor
- Vestre Viken Hospital Trust
Anterior Cruciate Ligament Injury, Knee Injury
Optimizing Plyometric Training for Functional Recovery Post-ACL Reconstruction
While surgical anterior cruciate ligament reconstruction (ACLR) of the knee restores passive stability, studies are showing consistently poor long-term outcomes.
- Trial name
- NCT02148172
- Testing
- Standard Plyometric Training, Plyometric Training with BWS
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Montana
Burns, Gait Training
Gait Training in Patients With Burn Injury
Twenty-four individuals with burn injury will be included in this study. Participants with burn injury will evaluate with the following assessment tools: Demographic datas; age, gender, height, body mass index; burn…
- Conditions
- Burns, Gait Training, Physical Functions
- Trial name
- NCT03217526
- Testing
- Gait Training
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Reconstruction
Effect of Intraoperative Live Video Viewing on Kinesiophobia After ACL Reconstruction
The purpose of this randomized controlled trial is to investigate whether intraoperative live arthroscopic video viewing improves postoperative psychological and functional outcomes in patients undergoing primary anterior…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Reconstruction, Kinesiophobia, Anxiety
- Trial name
- VIDEO-ACLR (NCT07540715)
- Testing
- Intraoperative Live Video Viewing, Standard ACL Reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Konya City Hospital
Aging, Asymmetry
Fall Risk in Adults Over 65: The Relevance of Morphological and Functional Lower Limb Asymmetries.
Falls among older adults represent a major public health burden. Approximately 30% of individuals aged 65 and older experience at least one fall each year.
- Conditions
- Aging, Asymmetry, Fall Risk Factors, Fall Prevention
- Trial name
- ASY&FALL (NCT07742397)
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Hand Injuries
Comparison of Upper Extremity and Lower Extremity Function and Quick DASH
Patient reported outcome measure (PROM) are a method by which to assess outcomes from a patient perspective. The QuickDASH is a commonly used PROM.
- Trial name
- NCT04291170
- Testing
- QDASH, KOOSJR
- Sponsor
- Stanford University
Child, Only
Effects of Bulgarian Exercises on Lower Limb Function in Children
The objective of this study is to investigate the Effect of Bulgarian bag exercises on lower limb function, posture and balance among school going students.
- Trial name
- NCT07248501
- Testing
- Bulgarian Bag Exercises
- Where
- Pakistan
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Limb Salvage
Outcomes in Lower Extremity Soft Tissue Sarcoma Patients After Limb Salvage
This study aims to: 1. validate the Finnish version of the Musculoskeletal Tumor Society scale and the Toronto Extremity Salvage Score lower extremity sections and to 2.
- Trial name
- NCT02536053
- Testing
- Limb salvage
- Where
- Finland
- Volunteers
- 141 people
- Sponsor
- Helsinki University Central Hospital